Cross-reactivitySpeciesRecombinantNeutrophilCytokinesEndothelial cellsLymphocytesVascularChemokinesMonocytesReceptorAssayAntibodyThymidine phosphorylaseCytokineMitogensImmuneExpressionGeneTumorPotentProteinHumanAntibodiesSignificantCellsTrigger factorsDifferentiationTranscriptionDiabetesRiskApplicationsTransforming growtStudiesProliferation
Cross-reactivity7
- No significant cross-reactivity or interference between Monocyte Chemotactic Protein 1 (MCP1) and analogues was observed. (uscnk.com)
- Species cross-reactivity detected in product development may not have been confirmed on every format and/or application. (bdbiosciences.com)
- HSP-65, found in high concentrations in oral ulcers and active skin lesions in patients with Behçet disease, has also been demonstrated to stimulate production of antibodies that exhibit cross-reactivity with streptococcal species present in the mouth. (medscape.com)
- Monoclonal antibodies were used to determine immune cross-reactivity between phylogenetically similar antigens. (asu.edu)
- Meanwhile, the cross-reactivity of CD8+ and CD4+ T cells response to Dengue and Zika viruses provide important clues for further development of potential treatments. (frontiersin.org)
- Consideration of the genetic identity of both the Dengue and Zika flaviviruses as well as the cross-reactivity of relevant T cells along with the actions of CD4+ cytotoxic cells in these infections are also presented. (frontiersin.org)
- There is no detectable cross-reactivity with other relevant proteins. (rockland.com)
Species2
- Human and murine IL-16 show significant cross-species reactivity. (reliatech.de)
- with no significant corss-reactivity with analogues from other species. (gkts.net)
Recombinant1
- Matrices listed below were spiked with certain level of recombinant Monocyte Chemotactic Protein 1 (MCP1) and the recovery rates were calculated by comparing the measured value to the expected amount of Monocyte Chemotactic Protein 1 (MCP1) in samples. (uscnk.com)
Neutrophil3
- Receptor for interleukin-8 which is a powerful neutrophil chemotactic factor. (joplink.net)
- Previous nomenclature for IL-8 includes neutrophil activating protein 1 (NAP-1), granulocyte chemotactic protein 1 (GCP-1), monocyte-derived neutrophil-activating peptide (MONAP) and protein 3-10C. (thermofisher.com)
- Characterization of a class of nonformylated Enterococcus faecalis-derived neutrophil chemotactic peptides: the sex pheromones. (google.no)
Cytokines7
- Background CXCL12a and CXCL12b, also known as Stromal Cell-Derived Factor 1a and 1b (SDF-1a and SDF-1b), are small cytokines that belong to the intercrine family. (qedbio.com)
- The activation and aggregation of immune cells in the gastric mucosa and submucosa includes epithelial-derived chemotactic peptides (chemokines), such as interleukin IL-8 and growth-regulated oncogene (GRO) -α, bacterial chemotaxis, and proinflammatory cytokines released by mononuclear phagocytes, such as tumor necrosis factor-alpha (TNF-α), IL-1, and IL-8 [ 16 , 17 ]. (biomedcentral.com)
- Among the important functions of the clot are its role as a reservoir of growth factors and cytokines that are released by the degranulation of activated platelets. (dentistryiq.com)
- The growth factors and cytokines present in the fibrin clot provide some of the start signals for wound repair. (dentistryiq.com)
- Macrophages continue cleansing the wound and releasing cytokines and growth factors. (dentistryiq.com)
- It is a reservoir of cytokines and growth factors, as well as signaling molecules, mitogens, and chemotactic factors. (dentistryiq.com)
- The inflammatory process in asthma involves the increased expression of various pro-inflammatory chemokines, cytokines, growth factors, lipid mediators, adhesion molecules, enzymes, and receptors for the same inflammatory mediators 21 . (ersjournals.com)
Endothelial cells2
- The expression of thymidine phosphorylase (TP), a potent chemotactic factor for endothelial cells, was studied in 60 adenocarcinomas of the gallbladder, by use of immunohistochemical techniques. (ox.ac.uk)
- It is both chemotactic and mitogenic for endothelial cells and a non-heparin binding angiogenic factor present in platelets. (thermofisher.cn)
Lymphocytes4
- Furthermore, CD31+ lymphocytes, frequently seen in carcinomas with high-fibroblastic TP reactivity, were connected with an improved survival. (ox.ac.uk)
- CXCL12 is strongly chemotactic for T- lymphocytes and monocytes, and it plays an important role in angiogenesis by recruiting endothelial progenitor cells (EPCs) from the bone marrow through a CXCR4 dependent mechanism. (qedbio.com)
- A CXC chemokine that is chemotactic for T-LYMPHOCYTES and MONOCYTES. (lookformedical.com)
- MPIF1 has chemotactic activity on resting T lymphocytes and monocytes, lower activity on neutrophils. (rockland.com)
Vascular5
- Postprandial lipemia and hyperglycemia suppress vascular reactivity and induce endothelial dysfunction. (encyclopedia.pub)
- Moreover, both postprandial lipemia and hyperglycemia are associated with reduced vascular reactivity and impaired endothelial function [ 12 ] [ 13 ] . (encyclopedia.pub)
- The synthesis of specific extracellular matrix molecules by fibroblasts in the wound is regulated by transforming growth factor-b1 and other factors such as insulin-like growth factor, interleukin 1a and 1b, interleukin-4, and vascular endothelial growth factor. (dentistryiq.com)
- The main factor in increasing systemic blood pressure is central and regional hemodynamic disorders: an increase in peripheral vascular resistance, a decrease in pulse blood supply to the brain, and hemodynamic disturbances in the pulmonary circulation. (artery-diseases-info.com)
- 12(S)-HETE is chemotactic and chemokinetic for polymorphonuclear leukocytes and vascular smooth muscle cells. (enzolifesciences.com)
Chemokines1
- Interleukin 8 (IL-8, CXCL8) is a 72 amino acid pro-inflammatory factor which belongs to the CXC subfamily of chemokines, and are bound by the cell surface receptors IL-8RA and IL-8RB. (thermofisher.com)
Monocytes2
- Description: Description of target: IL-8 is a chemotactic factor that attracts neutrophils, basophils, and T-cells, but not monocytes. (stainingkit.com)
- M-CSF affects macrophages and monocytes in several ways, including stimulating increased phagocytic and chemotactic activity, and increased tumour cell cytotoxicity. (m-csf.com)
Receptor5
- However, only the multimeric form appears to possess chemotactic activity, suggesting that receptor cross-linking may be required for activity. (reliatech.de)
- the opportunity for improved upon specialized medical benefits ought to be justified against logistical and also fiscal factors.Initial of the receptor with regard to sophisticated glycation endproducts (Anger) through it's ligands brings about mobile destruction causing diabetic issues. (mdmsignaling.com)
- Description: The APB5 monoclonal antibody reacts with the mouse CD140b molecule, the beta chain of the platelet derived growth factor receptor (PDGF receptor). (thermofisher.com)
- PDGFRb is a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. (thermofisher.com)
- The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. (thermofisher.com)
Assay3
- Intra-assay Precision (Precision within an assay): 3 samples with low, middle and high level Eosinophil Chemotactic Factor (ECF) were tested 20 times on one plate, respectively. (bioprodhub.com)
- Inter-assay Precision (Precision between assays): 3 samples with low, middle and high level Eosinophil Chemotactic Factor (ECF) were tested on 3 different plates, 8 replicates in each plate. (bioprodhub.com)
- This assay has high sensitivity and excellent specificity for detection of Monocyte Chemotactic Protein 1 (MCP1). (uscnk.com)
Antibody4
- The microtiter plate provided in this kit has been pre-coated with an antibody specific to Monocyte Chemotactic Protein 1 (MCP1). (uscnk.com)
- Standards or samples are then added to the appropriate microtiter plate wells with a biotin-conjugated antibody specific to Monocyte Chemotactic Protein 1 (MCP1). (uscnk.com)
- After TMB substrate solution is added, only those wells that contain Monocyte Chemotactic Protein 1 (MCP1), biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. (uscnk.com)
- Multiple procedures of freezing and thawing influence the specifity and reactivity of the antibody in a negative way. (m-csf.com)
Thymidine phosphorylase1
- A platelet-derived endothelial growth factor (PD-ECGF), same as thymidine phosphorylase (TP) or gliostatin. (thermofisher.cn)
Cytokine1
- This contrasts with findings from other body compartments that suggested that TGF-beta is a powerful chemotactic cytokine and increases microbial clearance. (uni-muenchen.de)
Mitogens1
- These growth factors are mitogens for cells of mesenchymal origin. (thermofisher.com)
Immune4
- In one of the subprojects, the influence of transforming growth factor-P (TGF-P) on the immune reactivity of the CNS was investigated. (uni-muenchen.de)
- The immune system is constituted by a very complex network of cells, tissues, and organs that through soluble factors and direct cell-to-cell contacts interact among themselves and with cells belonging to other (organ) systems. (frontiersin.org)
- If the organism is exposed to these factors during early life, when the maturing immune system is particularly susceptible, damages may be immediate, but can also emerge only late in life ( 4 ). (frontiersin.org)
- The innate immune system mainly comprises innate immune cells (macrophages: neutrophils, dendritic cells) and complement factors. (biomedcentral.com)
Expression2
- Sequence accessibility is an important factor affecting gene expression. (emerginginvestigators.org)
- In a PCR array analysis of 84 transcription factors, either overexpressing DEFB1 or siRNA silencing of DEFB1 expression significantly modulated the expression of signal transducer and activator of transcription 3 (STAT3). (cdc.gov)
Gene1
- There are many potential factors that affect the accessibility of a gene. (emerginginvestigators.org)
Tumor1
- It is this function of CXCL12 that makes it a very important factor in carcinogenesis and the neovascularisation linked to tumor progression. (qedbio.com)
Potent1
- IL-8 functions as a chemoattractant and potent angiogenic factor. (thermofisher.com)
Protein1
- The linearity of the kit was assayed by testing samples spiked with appropriate concentration of Monocyte Chemotactic Protein 1 (MCP1) and their serial dilutions. (uscnk.com)
Human1
- Human and non-human primate reactivity was determined by testing samples with the BD CBA Human IL-8 Flex Set. (bdbiosciences.com)
Antibodies1
- METHODS: Ninety eight patients with Acute myeloid leukemia (AML), Acute Lymphoblastic Leukemia (ALL) and lymphoma, selected from patients referring to Imam Reza Hospital of Tabriz (38°04'N 46°18'E), in terms of the presence of anti-Toxoplasma IgM, IgG, IgG avidity antibodies and the major risk factors were evaluated. (bvsalud.org)
Significant3
- High angiogenesis, assessed as microvessel density (MVD), was the most significant prognostic factor. (ox.ac.uk)
- With this method they identified several traits such as blood pressure readings, LDL cholesterol and BMI as significant risk factors. (emerginginvestigators.org)
- While other traits were not found to be significant risk factors. (emerginginvestigators.org)
Cells4
- Description: Description of target: Factor that induces terminal differentiation of late-developing B-cells to immunoglobulin secreting cells. (stainingkit.com)
- In the present review, we describe and discuss the effects of extremely low frequency (ELF)-EMF and pulsed EMF on cell signals and factors relevant to the activation of danger signals and innate immunity cells. (frontiersin.org)
- Complement factors circulate in the blood and are activated by the membrane of the microorganism to directly destroy the pathogen or activate phagocytic cells indirectly to eliminate the pathogen. (biomedcentral.com)
- M-CSF (or CSF-1) is a hematopoietic growth factor that is involved in the proliferation, differentiation, and survival ofmonocytes, macrophages, and bone marrow progenitor cells. (m-csf.com)
Trigger factors2
- On query, patient gives history of some trigger factors for breathlessness such as tree and grass pollen, cat and dog dander, cold air exposure, perfumes, and bleaches and food allergens. (pdfhost.io)
- This cough also aggravated in exposure to above mentioned trigger factors. (pdfhost.io)
Differentiation2
- Through various knock-out models, several transcription factors have been found to be essential in this differentiation, such as RUNX1 and TAL1 (also known as SCL). (wikipedia.org)
- MEP differentiation was found to be contingent upon the transcription factor GATA1, whereas GMP differentiation needs SPI1. (wikipedia.org)
Transcription1
- GRs), which ultimately alter transcription through direct DNA binding 31 or transcription factor inactivation 32 . (ersjournals.com)
Diabetes1
- Once a definitive diagnosis of Type II diabetes is established, physicians make a determination to control the glycemic level based on a number of factors including comorbidities affecting the cardiac, renal, ophthalmic and other physiological systems [4] The relationship between diabetes and periodontitis is not as clearly understood. (oatext.com)
Risk5
- It was concluded that H. pylori infection, as a chronic infection, can be considered a risk factor in developing WML in subjects with migraine. (biomedcentral.com)
- Role of Exposure and Risk Factors adult-onset nonoccupational asthma. (cdc.gov)
- Therefore, the purpose of this study is to use publicly available GWAS summary statistics to examine the causal relationship between coagulation factors and the risk of endometriosis. (biomedcentral.com)
- To investigate the causal relationship between coagulation factors and the risk of endometriosis, a two-sample Mendelian randomization (MR) analytic framework was used. (biomedcentral.com)
- Our two-sample MR analysis of 11 coagulation factors in the UK Biobank suggested a reliable causal effect of genetically predicted plasma ADAMTS13 level on decreased endometriosis risk. (biomedcentral.com)
Applications1
- The authors hypothesized that CDK5 would be able to overcome these barriers of Brownian motion and developed a quantitative model using Michaelis-Menten kinetics to define the necessary parameters to confirm and characterize CDK5's chemotactic behavior to establish its utility in drug delivery and other applications. (emerginginvestigators.org)
Transforming growt1
- Among these factors are epidermal growth factor, transforming growth factor alpha, heparin-binding epidermal growth factor, and keratinocyte growth factor. (dentistryiq.com)
Studies1
- Studies have shown that when purified growth factors were deposited in granulation tissue, the wounds showed accelerated granulation tissue formation and wound healing (Lynch et al. (dentistryiq.com)
Proliferation1
- Several growth factors seem to be key players in regulating the proliferation of keratinocytes in healing wounds. (dentistryiq.com)