Reactive Oxygen SpeciesOxygenOxidative StressPhosphatidylethanolamine Binding ProteinHydrogen PeroxideAntioxidantsNADPH OxidaseMitochondriaFree Radical ScavengersOxygen ConsumptionSuperoxide DismutaseOxidation-ReductionCatalaseAcetylcysteineApoptosisSuperoxidesMitochondria, HeartOxidantsCells, CulturedSignal TransductionEnzyme InhibitorsMembrane Potential, MitochondrialGlutathioneLipid PeroxidationOnium CompoundsReactive Nitrogen SpeciesSinglet OxygenXanthine OxidaseEnzyme ActivationProton-Translocating ATPasesSubmitochondrial ParticlesCyclic N-OxidesCell SurvivalCell Line, TumorProteinsMolecular Sequence DataCell DeathCell LineCattleBlotting, WesternAmino Acid SequenceDose-Response Relationship, DrugFree RadicalsPhosphorylationHydroxyl RadicalNF-kappa BAurovertinsNitric OxideAngioedemaRats, Sprague-DawleyAdenosine TriphosphateMice, Inbred C57BLDNA DamageKineticsGlutathione PeroxidaseTime FactorsRotenoneComplement C1 Inactivator ProteinsRNA, MessengerModels, BiologicalCaspasesProtein BindingAscorbic AcidMice, Knockout1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium SaltCarrier ProteinsLuminescent MeasurementsAcetophenonesRespiratory BurstCytochromes cXanthineAndrogen-Binding ProteinMitochondrial ProteinsPlant ProteinsVitamin K 3Oxygen Inhalation TherapyCalciumGene Expression RegulationMutationUp-RegulationAnoxiaCaspase 3I-kappa B ProteinsElectron Transport Complex IPeroxiredoxinsMetalloporphyrinsCell HypoxiaNeutrophilsEndothelium, VascularProtein CarbonylationDeoxyguanosineCell ProliferationReverse Transcriptase Polymerase Chain ReactionCell RespirationElectron TransportNF-E2-Related Factor 2Spin LabelsParaquatRats, WistarMalondialdehyde