Benzylamine is degraded biologically by the action of the monoamine oxidase B enzyme, resulting in benzaldehyde. (wikipedia.org)
We describe the development of quinolylnitrones (QNs) as multifunctional ligands inhibiting cholinesterases (ChEs: acetylcholinesterase and butyrylcholinesterase-hBChE) and monoamine oxidases (hMAO-A/B) for the therapy of neurodegenerative diseases. (bvsalud.org)
This aberrant astrocytic GABA is synthesized by the enzymatic action of monoamine oxidase B (MAOB), whose pharmacological inhibition and gene-silencing are reported to significantly alleviate parkinsonian motor symptoms in animal models of Parkinson's disease. (en-journal.org)
Semicarbazide-sensitive1
Methylamine and benzylamine induced hypophagia in mice: modulation by semicarbazide-sensitive benzylamine oxidase inhibitors and aODN towards Kv1.1 channels. (ncats.io)
Lysyl1
Lysyl oxidases (LOX and LOX-likes [LOXLs] isoenzymes) are copper-dependent enzymes involved in the covalent cross-linking of collagen and elastin, which allows extracellular matrix (ECM) assembly and influences the structural properties of connective tissues. (mdpi.com)
Enzyme1
Benzylamine occurs biologically from the action of the N-substituted formamide deformylase enzyme, which is produced by Arthrobacter pascens bacteria. (wikipedia.org)
Amine2
It was first produced accidentally by Rudolf Leuckart in the reaction of benzaldehyde with formamide in a process now known as the Leuckart reaction, a general process in which reductive amination of aldehydes or ketones yields the corresponding amine. (wikipedia.org)
The reaction takes place in a two-phase solvent system (here water and diethyl ether) so that the hydrogen chloride by-product is sequestered in the aqueous phase (and sometimes neutralised with a dissolved base) and thus prevented from protonating the amine and impeding the progress of the reaction. (wikipedia.org)
These conditions are often called Schotten-Baumann reaction conditions and are applicable more generally. (wikipedia.org)
It was found that screen-printed gold electrodes and a very low pH value (pH 1) are well-suited to perform the electrochemical detection of TMB, due to the reversible character of the redox reaction under these conditions. (kobv.de)
Role1
These reactions play an important role for the development, elasticity and extensibility of connective tissue. (expasy.org)
Derivatives2
Other derivatives of benzylamine and its salts have been shown to have anti-emetic properties, including those with the N-(3,4,5-trimethoxybenzoyl)benzylamine moiety. (wikipedia.org)
Commercially available motion-sickness agents including cinnarizine and meclizine are derivatives of benzylamine. (wikipedia.org)