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  • pellets
  • In the radial maze, HRA rats consistently needed less time to consume all pellets than LRA rats, which was due to faster locomotion on the arms and less time spent at the food pits (especially in baited arms) of HRA rats. (biomedsearch.com)
  • behavior
  • Compulsive cocaine-seeking behavior is influenced by cocaine dose but not estrous cycle in the female rats. (springer.com)
  • Substantial work has shown that rats although identical in stock, sex, age, and housing conditions can differ considerably in terms of behavior and physiology. (biomedsearch.com)
  • In the open field, HRA rats not only showed more rearing behavior, but also more locomotor activity than LRA rats. (biomedsearch.com)
  • In the plus-maze, HRA rats again showed more locomotion, but did not differ in open arm time or percentage of open arm entries, that is, conventional measures of anxiety-related behavior. (biomedsearch.com)
  • doses
  • Therefore, the metabolism of myosmine has been studied in Wistar rats treated with single oral doses of [pyridine-5-3H]myosmine at 0.001, 0.005, 0.5, and 50 micromol/kg body weight. (biomedsearch.com)
  • Subsequently, the same rats went on to self-administer intravenous cocaine and the punishment intensity-response effects on cocaine SA reinforced by different doses of cocaine were similarly determined. (springer.com)
  • chemistry
  • LCDP was also tested in normotensive rats and results obtained from chemistry analysis revealed slight variations in the levels of creatinine kinase (CK), serum glutamate oxaloacetic transaminase (SGOT), and alanine transaminase (ALT) levels. (hindawi.com)
  • Study
  • The present study was aimed at investigating the safety of Lacidipine (LCDP) loaded nanostructured lipid carriers (NLCs) in Wistar rats. (hindawi.com)
  • The present study was designed to investigate the pharmacodynamics and oral toxicity of PartySmart, a herbal formulation in rats. (redorbit.com)
  • To study this hypothesis, we isolated adrenal glands from control and spontaneously diabetic BB-Wistar rats, perfused them with ACh, and measured catecholamine secretion. (diabetesjournals.org)
  • The results from this study indicate that L.GG protects the intestinal mucosa of rats from PTG-induced damage, by preventing the reduction of the expression of the intercellular junction proteins. (mdpi.com)
  • alterations
  • A global profiling integrates for the first time pathways affected by high-cholesterol diet intake and allowed us to elucidate some of the associated alterations underlying the hypercholesterolemia event in Wistar rats. (springer.com)
  • Nascimento AR, Machado M, De Jesus N, Gomes F, Lessa MA, Bonomo IT, Tibiriçá E (2013) Structural and functional microvascular alterations in a rat model of metabolic syndrome induced by a high-fat diet. (springer.com)
  • reward
  • In general, working memory errors were more frequent in the arm with the large bait size, but there were no indications that HRA and LRA rats responded differently dependent on reward size. (biomedsearch.com)
  • results
  • The results indicate that developed LCDP loaded NLCs are safe when administered orally in rats. (hindawi.com)
  • made
  • Furthermore, HRA rats visited more arms and made relatively less reference memory errors than LRA rats. (biomedsearch.com)
  • Conversely, nondiabetic BB-Wistar rats made diabetic with streptozocin (STZ) and maintained in a hyperglycemic state did not exhibit catecholamine hyposecretion 2 weeks after STZ administration. (diabetesjournals.org)
  • response
  • We have demonstrated previously that spontaneously diabetic BB-Wistar rats exhibit decreased adrenal medullary catecholamine secretion in response to splanchnic nerve terminal stimulation. (diabetesjournals.org)
  • skin
  • The skin on the back of each rat was punched with two full-thickness wounds and then treated with the corresponding drug. (hindawi.com)
  • To identify the effective constituent in Dragon's blood that favors wound healing, we experimentally determined the mechanism by which DP accelerates wound healing on Wistar rat skin. (hindawi.com)
  • Skin and hepatic tumours are induced in rats by dermal application. (wikipedia.org)
  • oral
  • Weanling rats were exposed to 0, 3, 30, 100, 200, or 300 mg/kg of triclosan by oral gavage from postnatal day (PND) 23 to 53. (nih.gov)
  • less
  • The wires had to be anchored to reduce the probability of the rats' removal of the sensor, but the sensors showed less variation in glucose sensitivity over time than prior biosensors. (pubmedcentralcanada.ca)