• Methods: Male Wistar rats aged 8 10 weeks were orchiectomized and put on a low- (diet 0.03% NaCl+tap water) or high-salt diet (diet 4% NaCl+trinking water 0.09% NaCl) over 5 weeks. (endocrine-abstracts.org)
  • However, all the processing methods were ineffective when compared to the performance of rat fed casein based diets. (ajol.info)
  • Methods: Thirty-day-old female Wistar rats were submitted to IF for three months. (endocrine-abstracts.org)
  • Materials and Methods: A total of twenty five (25) male Wistar rats were divided into five groups as follows: Group 1 (Control) received distilled water (0.2 ml/100 g i.p.) for 5 consecutive days and thereafter left untreated for 28 days. (scopemed.org)
  • Methods and results: We determined the effect of piperine, quercetin, and polysorbate 80 coadministered with losartan on plasma levels in rats by HPLC assay. (eurekaselect.com)
  • Methods: The following oral treatments were given to diabetic rats for 30 days: (1) metformin 500 mg/kg, (2) baicalin 120 mg/kg, and (3) metformin 500 mg/kg & baicalin 120 mg/kg, with vehicle-treated diabetic and non-diabetic groups serving as controls. (nus.edu.sg)
  • H. Illnerova, J. Vaneek and K. Hoffmann, "Regulation of the Pineal Melatonin Concentration in the Rat (Rattus norvegicus) and the Djungarian hamster (Phodopus sungorus)," Comparative Biochemistry and Physiology, Vol. 74, No. 1, 1983, pp. 155-159. (scirp.org)
  • The histological effect of oral administration of sildenafil citrate (Viagra), commonly used as an aphrodisiac and for the treatment of erectile dysfunction on one of the visual relay centres namely the lateral geniculate body (LGB) of adult Wistar rat was carefully studied. (cogprints.org)
  • Significant increase in left testis weight and liver weight was observed in male and female rats, respectively. (hindawi.com)
  • Some of the liver drug metabolizing and detoxifying enzymes were depleted under toxic conditions compared with non-toxic rats. (mdpi.com)
  • This study demonstrates that streptozotocin, even in a dose of 30 mg/kg of body weight, has an exceedingly marked tumorigenic action on the rat pancreas, while it has little effect on the kidney and no effect on the liver. (aacrjournals.org)
  • In this study liver nodules were produced in Wistar rats by intermittent feeding with dietary 2-acetylaminofluorene, and the lipid compositions of isolated microsomes, mitochondria, and lysosomes were examined. (aacrjournals.org)
  • This study is designed to elucidate the chemopreventive properties of 18β-GA against 2-AAF-induced liver toxicity in Wistar rats and evaluated its effect on inflammatory and tumour promotion marker and activities of different oxidative stress enzymes. (sigmaaldrich.com)
  • Coriander extracts protect liver and lower lead concentration in rats intoxicated with lead in contrast to the positive control group. (nih.gov)
  • Effect of electromagnetic radiofrequency radiation on the rats' brain, liver and kidney cells measured by comet assay. (emf-portal.org)
  • The feeding trial lasted for 28 days after which four rats per treatments were sampled to evaluate haematological and serum biochemical indices while three rats per treatment were sacrificed by cervical decapitation and the heart, liver, kidneys and the lungs removed and weighed separately. (ajol.info)
  • Rats on control diet had the lowest relative weight for liver (3.74), lungs (1.03), kidney (0.92) and heart (0.49). (ajol.info)
  • Rats on T3 and T5 had the highest value for heart weight (0.75) and liver weight (5.67)while rats on T4 had the highest value for lungs (1.59).Rats fed dehulled jack bean seed soaked in ogi liquor showed slight improvement on haematological, serum profile and organ weight changes over those fed lye soaked jack bean and boiled for 15minutes. (ajol.info)
  • Innovative Grade US Origin Rat Sprague Dawley Liver from Innovative Research was used i. (innov-research.com)
  • Chronic symptoms include induction of hepatomas in rats, pulmonary tumours in mice, renal lesions and alterations in the liver and kidneys of African Green monkeys. (wikipedia.org)
  • Rats fed 5-10 mg/kg of sterigmatocystin for two years showed a 90% incidence of liver tumours. (wikipedia.org)
  • Collectively, the data describe decreased adrenomedullary response to cholinergic stimulation in spontaneously diabetic rats as early as 2 weeks after the onset of diabetes and that a similar, although more severe, hyposecretion occurs after acute, severe hypoglycemia. (diabetesjournals.org)
  • To determine the effect of vagotomy in early stages of experimental acute pancreatitis induced by occlusion of pancreatic duct in Wistar rats. (medigraphic.com)
  • Use of vagotomy improves the course of experimental acute pancreatitis in early stages in Wistar rats. (medigraphic.com)
  • The purpose of this study was to evaluate the acute toxicity and sedative effect of the ethylic extract of Thymelaea lythroides ( Tl ) on Wistar rats. (scirp.org)
  • In this study, we hypothesized that acute and prolonged conditional microglial ablation in a rat model would lead to improvements in learning and memory and that this would be associated with changes in synaptic pruning and neuronal maturation. (springer.com)
  • The result of the acute toxicity test showed that up to 5,000 mg/kg body weight of the extract did not cause any mortality of the wistar rats. (sciepub.com)
  • Therefore, the metabolism of myosmine has been studied in Wistar rats treated with single oral doses of [pyridine-5-3H]myosmine at 0.001, 0.005, 0.5, and 50 micromol/kg body weight. (biomedsearch.com)
  • The rats were tested in the open field prior to the Y-maze and then given voluntary intermittent access to alcohol or water in the home cage for 6 weeks, where after, naltrexone in three different doses or saline was administered in a Latin square design over 4 weeks and alcohol intake and preference was measured. (diva-portal.org)
  • Rats were divided into 5 groups (n=12,8 rat in each group),three group of rats gavaged with doses of 200,400 and 600μg/kg B.W Tamoxifen dissolved in solvent(ethanol 60% and physiological solution) for 30 days. (sid.ir)
  • Three groups of rats (200-250gr range) gavaged with doses of 200, 400 and 600ug/kg B.W Tamoxifen dissolved in solvent (ethanol 60% and physiological solution) for 30 days. (sid.ir)
  • The results of the present study showed that in spite of resistance training, use of TE in high doses can cause significantly alterations in some of hematologic factors in male rats. (springermedizin.de)
  • On days 1and 30 after the end of treatment, 6 ovarectomized rat from each group selected randomly and sections of uterus stained with H&E method were investigated histological and also 4 intact female rat from each group with male rats mate and the number of offspring's of them determined. (sid.ir)
  • In the major aim of this study is to investigate the effect of Tamoxifen on the histological structure of uterus estrogen, progesterone and LH concentration in the female Wistar rats. (sid.ir)
  • To evaluate the haematopoietic property of citrullus lanatus seed extract by determining the phytochemical, cytological and histological profiles on the bone marrow of wistar rats. (sciencedomain.org)
  • The present study aimed to evaluate the chronic effects in bone tissue of energy-protein restriction in rats during lactation period through a histological and morphometric analysis of the cortical mass of the femur. (jcdr.net)
  • LCDP was also tested in normotensive rats and results obtained from chemistry analysis revealed slight variations in the levels of creatinine kinase (CK), serum glutamate oxaloacetic transaminase (SGOT), and alanine transaminase (ALT) levels. (hindawi.com)
  • Rats were killed on PND 53, organ weights were recorded and serum was collected for subsequent analysis. (nih.gov)
  • We have recently shown that ozone exposure induces significant hyperglycemia together with elevated serum leptin and epinephrine in the Wistar Kyoto (WKY) rats, suggesting that neurohumoral mediators may be responsible for the ozone-induced metabolic impairment. (epa.gov)
  • Furthermore, after ozone exposure, serum triglycerides were decreased only in sham-operated but not BA rats. (epa.gov)
  • The Roux-en Y Gastric Bypass showed neither epsilon cell increase nor basal serum changes in ghrelin release. (medworm.com)
  • To study the effects of electromagnetic fields generated by mobile phones on serum testosterone levels in rats . (emf-portal.org)
  • The data showed that exposure to mobile phones for 60 minutes/day for the total period of 3 months significantly decreased the serum testosterone level in rats compared to the control group . (emf-portal.org)
  • Effects of simultaneous combined exposure to CDMA and WCDMA electromagnetic fields on serum hormone levels in rats. (emf-portal.org)
  • The present study was aimed at investigating the safety of Lacidipine (LCDP) loaded nanostructured lipid carriers (NLCs) in Wistar rats. (hindawi.com)
  • Here we provide a temporal course on lipid profile of cholesterol, triglycerides, HDL and LDH in Wistar rats treated with CED and FAD diet that can be useful as reference for future studies. (scirp.org)
  • Cortés-Ortiz, M. , Leal-Galicia, P. , Chávez-Álvarez, B. , Cárdenas-Aguayo, M. and Meraz-Ríos, M. (2014) Effect of Cholesterol Enriched or Fatty-Acid Diets on Cholesterol and Lipid Levels in Young Wistar Rats. (scirp.org)
  • However, in Gr.II rats,there was an increase in protein content, glutathione and antioxidant enzyme levels,tryptophan-fluorescence and inhibition in AGE-fluorescence and lipid peroxidation.In the tryptohan deficient animals the enzymatic degradation of tryptophan by IDO has been significantly reduced and therefore, it decreased the anti-oxidative effects of IDO itself. (arvojournals.org)
  • The present study was aimed at evaluating the mitigating effect of vitamin C on chronic CPF-evoked alteration in lipid profiles in Wistar rats. (thescipub.com)
  • The rats in group A (Control) were administered with 0.9% physiological saline, while rats in groups B, C, D, and E were administered with the extract of 1000, 2000, 4000 and 8000 mg per Kg body weight, respectively, once daily for 14 days. (academicjournals.org)
  • This study employed immunologic factors analysis, GC-TOFMS based metabolomics and 16S-rRNA-sequencing microbiome profiling technologies to explore the effects of E. purpurea on young rats, a physiological insufficient immunity status, by compared with pidotimod treatment on young rats and adult animals. (ccsenet.org)
  • The present study was designed to investigate the pharmacodynamics and oral toxicity of PartySmart, a herbal formulation in rats. (redorbit.com)
  • It is evident that the percentages of oxidative stress and immunity-related proteins were up-regulated in toxicity-induced rats as compared with nontoxic and control rats. (mdpi.com)
  • Vara Prasad WLNV, Srilatha Ch, Sailaja N, Raju NKB, Jayasree N (2016) Amelioration of gamma-hexachlorocyclohexane (lindane) induced renal toxicity by Camellia sinensis in Wistar rats, Veterinary World, 9 (11): 1331-1337. (veterinaryworld.org)
  • Cadmium-Induced Testicular Toxicity, Oxidative Stress and Histopathology in Wistar Rats: Sustained Effects of Polyphenol-Rich Extract of Vernonia Amygdalina (Del. (scopemed.org)
  • Aim: To determine the effects of polyphenol-rich extract of the leaf of Vernonia amygdalina (PEVA) on Cd-induced testicular toxicity, oxidative stress, and histopathology in Wistar rats. (scopemed.org)
  • These findings suggest that MON810 has negligible effects on the small intestine of rats at the cellular level compared with the well-documented toxicity observed in susceptible insects. (dtu.dk)
  • This text provides a complete account of this particular rat strain. (booktopia.com.au)
  • As controls for experiments utilizing SHRs, many scientists have employed normotensive descendants of Wistar rats that NIH investigators obtained in 1971 from a colony in Kyoto from which the SHR strain was originally derived (Wistar-Kyoto rats, WKY). (scielo.br)
  • Although it was previously reported that some normotensive Sprague Dawley rats spontaneously exhibit lower baroreflex sensitivity, 7,10 no previous study investigated whether there is difference in baroreflex sensitivity among other types of rats from the same parent strain. (scielo.br)
  • 11 Thus, in this study we aimed to compare baroreflex function among adult WKY rats from the same laboratory in order to identify any intra-strain differences. (scielo.br)
  • Overall these findings render RccHan™:WI rats more suitable for studies of individual differences in voluntary alcohol intake and response to naltrexone and further highlight the inherent heterogeneity of the Wistar strain. (diva-portal.org)
  • Wistar rats, an animal strain widely used in the research have been employed to study the effects of dietary interventions due to their metabolic characteristics, which are closer to the human compared to mice. (scirp.org)
  • however, this effect was small (~30%), within the normal range of sperm counts for this strain of rat, was not reflected in testicular spermatid counts nor PND70 data, and is therefore postulated to have no biological significance. (nottingham.ac.uk)
  • Complement/sera from mouse (CD1 and C57BL/6 strains), rat (Wistar strain), guinea pig and human were purchased from Innovative Research (Novi, MI) . (innov-research.com)
  • 0.05) difference in the mean values of semen volume of rats in the control and test groups. (academicjournals.org)
  • 0.05) decreased the gastric volume, total acidity, free acidity and increase in the pH of the gastric fluid in pylorus-ligated rats. (ijpsonline.com)
  • 0.05) decrease in number of ulcers, ulcers score and ulcer index in pylorus ligated and indomethacin treated rats. (ijpsonline.com)
  • Decrease in body weight and organ development in the deficient animals was noticied and these changes were not seen in the rats that recevived 0.05% tryptophan. (arvojournals.org)
  • 0.05) different from rats on T1, T2, T3, and T5 with rats on T3 having the highest value (3.42). (ajol.info)
  • Wistar rats of 60 days of life underwent stereotactic surgery and were divided into two groups: control (infusion of saline 0.9%) and hypoxanthine (10 μM). (springer.com)
  • Male WKY rats (11 week old) underwent sham-operation or bilateral adrenalectomy (BA), thus removing further secretion of glucocorticoids, mineralcorticoids, and catecholamines. (epa.gov)
  • Twelve adult male, Wistar rats underwent SG and were reoperated 30 or 60 days after the initial surgery. (scielo.br)
  • The objective of this study is to look for preoperative predictors of early T2DM relapse/no remission in patients with obesity and diabetes who underwent Roux ‐en‐Y gastric bypass (RYGB) or loop duodeno‐jejunal bypass with sleeve gastrectomy (LDJB‐SG). (medworm.com)
  • All rats underwent occlusion of pancreatic duct. (medigraphic.com)
  • Adult Wistar rats were instrumented to record ABP via telemetry, and then underwent CSD (n = 9) or sham CSD (n = 9) 5 weeks after renal artery clipping, in comparison with normal Wistar rats (n = 5). (ox.ac.uk)
  • Moreover, when compared to the control rats, the animals treated with 5000 mg/kg of the extract exhibited significant reduction in appetite for food and water in the first week. (scirp.org)
  • Ethanol extract was evaluated at dose levels of 100, 250, 500 mg/kg on fertility, implantation, decidualization and local cytokine signaling during decidualization in female Wistar rats with artificially induced decidualization. (ijpsonline.com)
  • The present study revealed that Moringa oleifera ethanol extract at dose level 250 and 500 mg/kg produced antifertility activity by inhibiting the implantation in female rats, which required further evaluation for potential contraceptive action. (ijpsonline.com)
  • It was concluded that extract of L. breviflora exerts toxic effect on the seminiferous tubular epithelium with concomitant reduction in the reproductive potential of the male rats. (academicjournals.org)
  • The objective of the present study was to investigate the antiulcer activity of methanol extract of Oxalis corniculata (whole plant) using pylorus ligation and indomethacin-induced gastric ulceration in Wistar rats. (ijpsonline.com)
  • Hence, the present work was designed to investigate the antiulcer potential of methanol extract of Oxalis corniculata in pylorus ligation and indomethacin-induced rat ulceration model. (ijpsonline.com)
  • As a step in this direction, this study was carried out on effects of aqueous leaf extract of Citrus medica on Neurobehavioral study of the Prefrontal cortex of hyperglycemic Wistar rats. (omicsonline.org)
  • Aqueous leaf extract of Citrus medica showed ameliorative potentials on the Prefrontal cortex of adult male Wistar rats against the damage initiated by hyperglycemia. (omicsonline.org)
  • The purpose of this research is to evaluate the chelating effect of methanol extract of coriander and its fractions on Wistar rats intoxicated with lead. (nih.gov)
  • In this research, male Wistar rats were poisoned with 50 mg/kg of lead acetate and treated with 50 mg/kg of methanol extract and its fractions. (nih.gov)
  • Male wistar rats (n = 24) were randomly divided into four groups, including Group I (control), Group II (250 mg kg 1 ), Group III (500 mg kg 1 ) and Group IV (1000 mg kg 1 ) and they were administered the extract for 28 days. (scialert.net)
  • Ikpeazu O.V., Elekwa I., Ugbogu A.E., Arunsi U.O., Uche-Ikonne C.. Preliminary Evaluation of Anti-ulcer Potential of Aqueous Extract of Fermented Unripe Musa paradisiaca in Wistar Rats. (sciepub.com)
  • The highly elevated aldosterone levels in rats on low salt diet with spironolactone or flutamide treatment were reduced by androgen treatment. (endocrine-abstracts.org)
  • To test these hypotheses, plasma glucose and insulin levels were measured in obese prediabetic Wistar-Fatty rats after two episodes of diet switching, with and without concomitant weight loss. (nih.gov)
  • After 7 weeks of experimental feeding, the rats were euthanized for blood collection and plasma recovery. (springer.com)
  • Effects of Opium Dependency on Testicular Tissue in a Rat Model: An Experimental Study. (harvard.edu)
  • This study aims to establish an experimental model of correction for large diaphragmatic defect with PB and GT patches to compare histologically the tissue interaction between them and diaphragm in young Wistar rats. (scirp.org)
  • To investigate the potential therapeutic effect of this broad-spectrum chemokine antagonist, we studied the antiinflammatory activity of vMIP-II in a rat model of experimental glomerulonephritis induced by an antiglomerular basement membrane antibody. (rupress.org)
  • Twenty-two-month-old Wistar rats and SAMP8 (senescence prone) mice of 10 months of age were used as experimental models. (eurekaselect.com)
  • After 72 hours, rats were killed, and (P)RR protein levels in plasma, urine and kidney were examined by using Western blot. (ahajournals.org)
  • To better understand the role that water and urea fluxes play in the urine concentrating mechanism, we determined transepithelial osmotic water permeability (Pf) and urea permeability (Purea) in isolated perfused Munich-Wistar rat long-loop descending thin limbs (DTLs) and ascending thin limbs (ATLs). (sigmaaldrich.com)
  • On days 3 and 5, 24-h rat urine excretion was collected. (rupress.org)
  • leaf (MOGL) on urine proteincreatinine ratio (UPC) was determined in rats with GEN-induced kidney injury. (ajol.info)
  • Male Wistar rats were fed with two different diets [control (C) and high-cholesterol diet (HC)-containing 2 % cholesterol and 0.5 % cholic acid]. (springer.com)
  • Greenwood, C.E. and Winocur, G. (1996) Cognitive Impairment in Rats Fed High Fat Diets: A Specific Effect of Saturated Fatty-Acid Intake. (scirp.org)
  • To address this important knowledge-gap and to gain insights into the underlying molecular responses in rat to MON810, differential gene expression in the epithelial cells of the small intestine of rats fed formulated diets containing MON810, its near isogenic line, two conventional corn varieties, and a commercial (Purina™) corn-based control diet were investigated using comparative proteomic profiling. (dtu.dk)
  • No adverse clinical or behavioural effects, or biomarkers of adverse health, were observed in rats fed GM corn compared to the other corn diets. (dtu.dk)
  • Initially the animals (newborn male Wistar rats) consumed the diets containing MSG for a period of 70 days. (scirp.org)
  • This study substantiated that MOGL has therapeutic potentials that becomes deleterious after sub-chronic administration in rat model of GEN-induced kidney injury. (ajol.info)
  • The experiments were performed on 16-week-old male WKY rats from the same initial laboratory. (scielo.br)
  • At day 0, male WKY rats (Charles River Laboratories, Wilmington, MA), 10-12 weeks of age and 200-220 g of body weight, were given one intravenous injection of anti-GBM antibody (( 7 )) at a dose of 25 μl/100 g body weight. (rupress.org)
  • Animals: Laboratory bred Wistar rats of either sex were used for the experiments. (redorbit.com)
  • There is variability regarding baroreflex sensitivity among WKY rats from the same laboratory. (scielo.br)
  • Rats were housed individually in plastic cages under standard laboratory conditions. (scielo.br)
  • Laboratory rats are the most popular animals in toxicology, neurobehavioral, or cancer research. (mdpi.com)
  • In this study, we exposed 30 laboratory-raised Wistar rats, a suitable model for the infestation, at six different places characterized by different microenvironments in a hyperendemic fishing village in northeastern Brazil. (ajtmh.org)
  • Apomorphine, an unselective dopamine Dl and D2 receptor agonist, induces in laboratory animals (mice and rats), several behavioural phenomena such as stereotyped behaviour, hyperlocomotion, aggressiveness, etc 1-3 . (springer.com)
  • Four groups of rats with 18 each were maintained under standard laboratory hygienic conditions and provided feed and water ad libitum . (veterinaryworld.org)
  • Finally, both CED and FAD induced a decrease in HDL as compared to control levels in treatments of more than 6 weeks, whereas LDL transiently increased in animals treated with FAD from 10 to 12 weeks, but after this period LDL levels returned to baseline, suggesting that young rats have a compensatory effect at least for the period of time analyzed here. (scirp.org)
  • Development of the muscular saphenous artery and the effect of surgical denervation on normal development was investigated in young rats at 3 and 6 weeks of age. (ahajournals.org)
  • Both the immunologic factors and the global metabolome of E. purpurea treated young rats were close to the status of mature individuals. (ccsenet.org)
  • Results: Transmission electron microscopy imaging of pancreatic β-cells revealed loss of integrity of the inner membrane of the mitochondria in the diabetic rats, which was not observed in the baicalin-treated group. (nus.edu.sg)
  • BACKGROUND A previous study indicated that selectively bred alcohol-preferring (P) rats self-administered ethanol (EtOH) directly into the ventral tegmental area (VTA), whereas the alcohol-nonpreferring line did not. (semanticscholar.org)
  • The effects of triclosan on puberty and thyroid hormones in male Wistar rats. (nih.gov)
  • The purpose of this study was to determine effects of triclosan on pubertal development and thyroid hormone concentrations in the male rat. (nih.gov)
  • Beneficial effects of dapsone on ischemia/reperfusion injury following torsion/detorsion in ipsilateral and contralateral testes in rat. (harvard.edu)
  • Based on this claim, the present study investigated the effects of Citrus sinensis (sweet orange) essential oil on Wistar, male rats evaluated in the elevated plus-maze followed by the light/dark paradigm. (nih.gov)
  • Furthermore, results of the psychotropic test conducted during this study showed visible effects on the exploratory activity of the rats. (scirp.org)
  • Our present study aims to investigate the interaction of melatonin (MEL) with this system by exploring the effects of MEL with or without a facilitator of GABA-ergic neurotransmission, diazepam (DZ) on the levels of depression and anxiety in Wistar rats. (scirp.org)
  • Colonic and systemic effects of extruded whole-grain sorghum consumption in growing Wistar rats. (nextbio.com)
  • Varying dosage and long administration of sildenafil citrate may have some deleterious effects on the neurons of the intracranial visual relay centre and this may probably have some adverse effects on visual sensibilities by its deleterious effects on the cells of the lateral geniculate body (LGB) of adult Wistar rats. (cogprints.org)
  • Arterial wall and smooth muscle cell development in young Wistar rats and the effects of surgical denervation. (ahajournals.org)
  • Two new quinoxalinone derivatives have been synthesized adopting the HONG method, and investigated for some neuropharmacological effects (anxietyand depressive-like responses) in rats. (scirp.org)
  • Effects of electromagnetic field produced by mobile phones on the oxidant and antioxidant status of rats. (emf-portal.org)
  • A study to assess the toxic effects of gamma-hexachlorocyclohexane (γ-HCH) (lindane) and ameliorative effects of Camellia sinensis on renal system has been carried out in male Wistar rats. (veterinaryworld.org)
  • Malgor L, Valsecia M, Verges E et al (1997) Blockade of the in vitro effects of testosterone and erythropoietin on Cfu-E and Bfu-E proliferation by pretreatment of the donor rats with cyproterone and flutamide. (springermedizin.de)
  • The effects of omega 3 fatty acid supplementation on brain tissue oxidative status in aged wistar rats. (semanticscholar.org)
  • Overexpression of hyperpolarization-activated cyclic nucleotide-gated channels into the ventral tegmental area increases the rewarding effects of ethanol in UChB drinking rats. (semanticscholar.org)
  • Maternal malnutrition during lactation has negative effects on femur growth even after normalization of the diet in adult aged Wistar rats. (jcdr.net)
  • However, supplier-dependent differences and concomitant skew subgroup formations, primarily in open field behavior and intermittent alcohol intake, resulted in a shifted focus to instead study voluntary alcohol intake and preference, and the ensuing response to naltrexone in Wistar rats from three different suppliers. (diva-portal.org)
  • Substantial work has shown that rats although identical in stock, sex, age, and housing conditions can differ considerably in terms of behavior and physiology. (biomedsearch.com)
  • In the open field, HRA rats not only showed more rearing behavior, but also more locomotor activity than LRA rats. (biomedsearch.com)
  • In the plus-maze, HRA rats again showed more locomotion, but did not differ in open arm time or percentage of open arm entries, that is, conventional measures of anxiety-related behavior. (biomedsearch.com)
  • Diazepam (1 h before the tests) reduced anxiety-like behavior in rats forced to swim compared to the vehicle stressed group. (srce.hr)
  • The dose-response curve for diazepam indicated that the 0.5 mg kg-1 dose (1 h before the EPM and OFT) was the minimum effective dose in reducing anxiety-like behavior without altering locomotor activity in weaning rats. (srce.hr)
  • These results indicate that weaning rats can develop anxiety-like behavior after a brief, single session of stress, and that rats at this age are seemingly more sensitive to diazepam than adult rats, which may be taken into account for clinical applications. (srce.hr)
  • have reported supplier-dependent differences in alcohol intake, open field and Y-maze behavior, and responsivity to opioid antagonist naltrexone in outbred Wistar rats obtained from three different vendors in Europe. (frontiersin.org)
  • Calvo-Ochoa, E., Hernández-Ortega, K., Ferrera, P., Morimoto, S. and Arias, C. (2014) Short-Term High-Fat-and-Fructose Feeding Produces Insulin Signaling Alterations Accompanied by Neurite and Synaptic Reduction and Astroglial Activation in the Rat Hippocampus. (scirp.org)
  • Marked morphological changes were also observed in the CA(3) region of the hippocampus of the mobile phone-exposed rats in comparison to the control rats. (buergerwelle.de)
  • We therefore undertook this study to evaluate pharmacodynamics and toxicological profile of oral administration of PartySmart in rats. (redorbit.com)
  • Our study compared baroreflex sensitivity among conscious rats of this specific subtype. (scielo.br)
  • In addition, a previous study demonstrated that WKY rats from two different laboratories showed differences in arterial pressure and growth rate. (scielo.br)
  • Our study provides an important insight into sex-specific differences in energy metabolism in rats and indicates that further studies should consider sex as the main aspect in design and data interpretation. (mdpi.com)
  • All rats were sacrificed and submitted to excision of pancreas for histopatologic study. (medigraphic.com)
  • In this study, types of fibers constituting male Wistar rats semitendinous and their myosin heavy chains, as well as influence of intermittent training on hypertrophy of these fibers have been checked through MATPase histochemical technique and electrophoretic proteins separation. (scielo.cl)
  • The present study investigated the sensitivity to stress and diazepam in weaning (21-day old) Wistar rats. (srce.hr)
  • None of rats used in this study developed hepatic tumors. (aacrjournals.org)
  • The aim of this study was to investigate the effect of allopregnanolone on intake of standard chow in male Wistar rats at different time points of the day. (diva-portal.org)
  • In conclusion, even though our study proves both unilateral left and bilateral hot water vestibular stimulation is beneficial in Scopolamine induced dementic rats in improving spatial cognition as well as motor control, unilateral left vestibular stimulation was found to be more beneficial. (alliedacademies.org)
  • Healthy male Wistar rats (weighing 40.0 ± 10.0 g, 21 days), reared in the Animal Facility of the University of Campinas (Unicamp), were used in this study. (scirp.org)
  • This study aimed to evaluate iron (Fe) bioavailability in Wistar rats fed with rice fortified with micronized ferric pyrophosphate (FP) by Ultra Rice® (UR) technology with or without addition of yacon flour as a source of 7.5% of fructooligosaccharides (FOS). (alanrevista.org)
  • We conclude that dietary APP has an anti-adipogenic effect in Wistar rats without any anorectic phenomenon. (go.jp)
  • In this paper, attempts were made to determine the effect of MEin rat stroke model. (magiran.com)
  • The food intake in rats varies diurnally and that may influence the effect of GABA(A)-receptor active compounds. (diva-portal.org)
  • Therefore, it is easy to envisage that allopregnanolone would have a hyperphagic effect, but earlier reports in rat have given ambiguous results. (diva-portal.org)
  • We evaluated the effect of RF-EMR from mobile phones on passive avoidance behaviour and hippocampal morphology in rats. (buergerwelle.de)
  • Davasaztabrizi A, Rakhshiasl A, Mousavi G, Rakhshiasl P (2012) Evaluating the effect of high concentration of testosterone enanthate on some of blood factors in male rat. (springermedizin.de)
  • Swathilatha Rewanthwar and P.K. Lakshmi, "Effect of Piperine, Quercetin, Polysorbate 80 on the Oral Bioavailability of Losartan in Male Wistar Rats", Pharmaceutical Nanotechnology (2014) 2: 49. (eurekaselect.com)
  • amongst others, showed that parenteral (4.0 mg/g b.w.) or oral (2.5 and 5.0 g/day) administration of MSG in newborn rats resulted in an injurious effect on the arcuate nucleus of the hypothalamus. (scirp.org)
  • Effect of sex hormones on plasma phospholipid fatty acid composition in intact rats and rats with bilaterally occluded carotid arteries. (semanticscholar.org)