• Wistar rats) [155], failed to influence food intake during a 1 h ad libitum feeding period, moderate to high doses of CBD (4.4 mg·kg −1 , i.p. [58]. (researchgate.net)
  • It was observed that in male Wistar rats, the administration of asiaticoside derivatives of Centella asiatica caused the restoration of 40% of the damaged liver cells to normal state [ 4 ]. (ijpsonline.com)
  • To test this hypothesis, basal extracellular concentrations of dopamine (DA) and serotonin (5-HT) in the nucleus accumbens as well as the effects of repeated ethanol pretreatment on the basal release of these transmitters were examined in alcohol-preferring (P), alcohol-nonpreferring (NP), and genetically heterogeneous Wistar rats. (aspetjournals.org)
  • In ethanol-naive rats, significant line differences were observed with high basal 5-HT release in P rats, low 5-HT release in NP rats, and intermediate 5-HT levels in Wistar rats. (aspetjournals.org)
  • Ethanol pretreatment decreased basal extracellular 5-HT levels in P rats whereas increasing 5-HT efflux was seen in the Wistar and NP lines. (aspetjournals.org)
  • In addition, ethanol pretreatment increased extracellular DA concentrations in Wistar and P rats, but not in NP rats. (aspetjournals.org)
  • No association between periodontitis, preterm birth, or intrauterine growth restriction: experimental study in Wistar rats. (bvsalud.org)
  • The present study was then conducted to verify the biologic plausibility of such association by experimentally inducing periodontitis in Wistar rats . (bvsalud.org)
  • Forty female Wistar rats were included in 2 groups a periodontally healthy (without ligatures ) and an experimentally induced periodontitis group (test, with ligatures ). (bvsalud.org)
  • The induced periodontitis in Wistar rats did not result in adverse outcomes of pregnancy . (bvsalud.org)
  • The present research aims to examine a periodontal disease model in which specific pathogen-free Wistar rats are orally exposed to Porphyromonas gingivalis associated with Fusobacterium nucleatum . (bvsalud.org)
  • Twenty adult male Wistar rats were divided into two groups. (bvsalud.org)
  • Our study showed that four weeks following infection with Porphyromonas gingivalis and Fusobacterium nucleatum bone loss in Wistar rats could be identified. (bvsalud.org)
  • Thirty-nine male Sprague-Dawley rats (Charles River, Wilmington, MA) were used in this study. (hindawi.com)
  • Thirty-two male Sprague-Dawley (SD) rats were randomly divided into four groups ( n = 8): normal control group, UC control group, UC+ST36 group and UC+non-acupoint group. (wjgnet.com)
  • Thirty adult male Sprague-Dawley rats were randomly divided into five experimental groups (6 rats per group). (researchgate.net)
  • Male rats of Jcl:Sprague-Dawley strain were purchased from CLEA Japan, Inc. (Osaka, Japan). (aspetjournals.org)
  • Sprague Dawley rats were treated with alcohol extract of Centella asiatica orally in two doses (20 and 40 mg/kg/day) for 3 mo along with intraperitoneal injection of carbon tetrachloride (1 ml/kg). (ijpsonline.com)
  • Male Sprague Dawley rats weighing 250-280 g were used for the experiment. (ijpsonline.com)
  • In this experiment, Sprague-Dawley rats were randomly divided into 4 groups: control, chronic unpredictable mild stress (CUMS), acupuncture, and fluoxetine groups. (medscimonit.com)
  • meats, biological trials were conducted on Albino rats of the Sprague-Dawley albino rats. (who.int)
  • The purpose of this study was to determine the effects of insulin and of endurance exercise on skeletal muscle sorbitol levels in streptozotocin-induced diabetic rats. (hindawi.com)
  • Here, we examined in male rats whether acute exposure (7-9 days) to HFD during juvenility [from postnatal day (PND) 21 to PND 28-30] or adulthood (from PND 60 to PND 67-69) is sufficient to affect hippocampal functions and whether it is also dependent on GRs activation. (nature.com)
  • To test whether AMPA or NMDAR subunits undergo activity-dependent modifications in adult hippocampal synapses, we induced LTP at perforant path-dentate gyrus (DG) synapses in anesthetized adult rats, using high frequency stimulation (HFS), verified layer-specific Arc induction, and analyzed the distribution of postsynaptic AMPA and NMDAR subunits, using immunogold electron microscopy. (unboundmedicine.com)
  • Thyroid deficiency can impair hippocampal neurogenesis, differentiation, and maturation in developmental and adult rat brains, suggesting a similar mechanism in humans. (medscape.com)
  • The results demonstrated that propofol-induced impairment in spatial learning and memory of rats and promoted oxidative stress, neuronal injury and apoptosis in rat hippocampal tissues. (degruyter.com)
  • After behavioral tests were completed, serum, feces, and hippocampal tissue of rats were collected. (medscimonit.com)
  • In this study, proteomics and metabonomics techniques were used to analyze the tissue and plasma of DOX-induced heart failure (HF) in rats and to clarify the molecular mechanism of the harmful effects of DOX on cardiac metabolism and function in rats from a new point of view. (frontiersin.org)
  • This study was aimed at investigating the effects of quercetin on mRNA expression and activity of critical enzymes in homocysteine metabolism in rats fed a methionine-enriched diet. (hindawi.com)
  • Most interestingly, gender-specific proteome comparison showed that male and female rats displayed differential regulation of proteins involved in muscle contraction, carbohydrate, and lipid metabolism, as well as oxidative phosphorylation and cellular stress. (karger.com)
  • These findings suggest that vitamin C significantly reduced the severity and incidence of fluoride-induced embryo toxicity in rats. (fluoridationaustralia.com)
  • See also ⇓ Ameliorative Effects of Quercetin on Sodium Fluoride - Induced Oxidative Stress in Rat's Kidney These findings suggest that vitamin D significantly reduced the severity and incidence of fluoride-induced embryo toxicity in rats. (fluoridationaustralia.com)
  • 21-Day repeated exposure inhalation toxicity in the rat. (cdc.gov)
  • There is also evidence of variation in toxicity between rat species. (unodc.org)
  • Rats were assigned to one of five experimental groups (control sedentary, control exercise, diabetic sedentary, diabetic exercise, diabetic sedentary no-insulin). (hindawi.com)
  • Diabetic rats received daily subcutaneous insulin. (hindawi.com)
  • Diabetic sedentary rats receiving insulin had similar sorbitol levels to control sedentary rats. (hindawi.com)
  • Interestingly, when sorbitol formation was inhibited by giving an aldose reductase inhibitor (ARI) to streptozotocin- (STZ-) induced diabetic rats, skeletal muscle sorbitol levels were lowered, and muscle contractile properties significantly improved [ 2 ]. (hindawi.com)
  • Our goal was to mimic the conditions observed in clinical settings by administering insulin to the STZ-induced diabetic rats. (hindawi.com)
  • To examine gender-dimorphic regulation of skeletal muscle proteins between healthy control and STZ-induced diabetic rats of both genders, we performed differential proteome analysis using two-dimensional electrophoresis combined with mass spectrometry. (karger.com)
  • Proteomic analysis of skeletal muscle identified a total of 21 proteins showing gender-dimorphic differential expression patterns between healthy controls and diabetic rats. (karger.com)
  • The current proteomic study revealed that impaired protein regulation was more prominent in the muscle tissue of female diabetic rats, which were more susceptible to STZ-induced diabetes. (karger.com)
  • Aim: Find an efficient way to enhance fracture healing by applying gene therapy to a diabetic rat model. (bl.uk)
  • 2) Build a fracture model in diabetic rats and investigate the relation between BMP-6 and impaired fracture healing. (bl.uk)
  • Radiological, histological and biomechanical comparison was made between fracture healing in diabetic and non-diabetic rats. (bl.uk)
  • 3) Carry out local BMP-6 gene delivery to fractured rats with diabetes and investigate effects of gene therapy on fracture and diabetic metabolic disorders. (bl.uk)
  • A significant inhibition in the expression of endogenic BMP-6 was found related to the impaired fracture healing in diabetic rats. (bl.uk)
  • Achievements & Benefits: A stable and repeatable fracture model in diabetic rats was built and optimized during this study. (bl.uk)
  • Impaired fracture healing was found in diabetic rats. (bl.uk)
  • It was the first time that BMP-6 gene therapy was applied to a fracture model in diabetic rats. (bl.uk)
  • Diabetic GK rats and control animals were randomly assigned to receive E4 or vehicle by intravitreal injection. (molvis.org)
  • In young postnatal day 12 (P12) rats, at least 4 d of deprivation were required to significantly weaken L4-L2/3 synapses. (jneurosci.org)
  • When whiskers are deprived by trimming or plucking in adolescent rats [postnatal day 7 (P7) to P60], L2/3 neurons in deprived barrel columns lose responsiveness to their deprived principal whisker, whereas L4 neuronal responses are unaffected. (jneurosci.org)
  • Rat pups were treated on the first postnatal day with a single intraperitoneal dose of T-2 toxin (0.2 mg/bwkg). (akjournals.com)
  • Animal experiments revealed that STZ treatment rendered female rats more susceptible to induction of diabetes than their male littermates with significantly lower plasma insulin levels due to hormonal regulation. (karger.com)
  • Non-Status Epilepticus female rats show seizure-like behaviors in the chronic phase of Pilocarpine experimental model. (scielo.br)
  • They then tested the effects of different dosages of spironolactone injections on operant alcohol self-administration in alcohol-dependent and nondependent male and female rats, also testing blood alcohol levels and motor coordination. (medscape.com)
  • Based on our recent silibinin efficacy studies in human colorectal cancer cells, we investigated the effects of its dietary feeding on azoxymethane (AOM)-induced aberrant crypt foci (ACF) formation and associated biomarkers in male Fisher 344 rats. (nih.gov)
  • Five-week-old male Fisher 344 rats were fed control or silibinin-supplemented (0.033%, 0.1%, 0.33%, or 1%, w/w) diet. (nih.gov)
  • The team placed 10-month-old male rats in cages with enriched environments and gave them plenty of space, a large running wheel and objects to explore. (medicalnewstoday.com)
  • By oral route, LD 50 is greater in female than in male rats. (unodc.org)
  • The experiment used groups of male weanling Fisher-344 rats (N=7- -8/group) fed a basal torula yeast, Se-deficient diet supplemented with 0, 0.02, 0.05, or 0.1 mg Se (as sodium selenite)/kg diet. (usda.gov)
  • 1992) that chloroquine treatment of rats eventually would lead to infertility by resulting in late germ cell developmental with depletion of spermatids (Abayomi O, 1992).This suggested the requirement for the quinine to occupied a place as a male contraceptive agent in humans (Osinubi et al. (researchgate.net)
  • In the present work, we describe the effects of dopamine depletion after the administration of 6-hidroxidopamine (6-OHDA) into the substantia nigra pars compacta of male rats submitted to the pilocarpine model of epilepsy. (scielo.br)
  • In order to test it, we placed adult male rats in a square open-field and recorded their position as a function of the number of circumscribing walls. (bvsalud.org)
  • Rats were each intratracheally instilled with 0, 1, 2.5, or 7.5mg of a test dust. (cdc.gov)
  • An experimental study on an animal model by the induction of periodontitis in 50% of sites and assessment of the presence of cytokines in the gingival tissue , serum , placenta , cord, and amniotic fluid was designed to test the null hypothesis that experimental periodontitis that is induced on rats does not result in adverse pregnancy outcomes . (bvsalud.org)
  • Plasma Hcys concentration and the activities of glutathione peroxidase (GPx) and BHMT decreased with decreasing dietary selenium with values from the 0 Se group being markedly lower, especially compared to values from the rats fed 0.05 0.1 Se. (usda.gov)
  • Since then, this rat HEVhas been detected in multiple wild rat species in the United States, Vietnam, Germany, and Indonesia ( 3 - 7 ). (cdc.gov)
  • The red rock rat, or red veld rat, (Aethomys chrysophilus) is a species of rodent in the family Muridae native to southern Africa. (wikipedia.org)
  • Although red rock rats can be distinguished from most other species of the genus Aethomys by their size or bodily proportions, they appear essentially identical to Tete veld rats, and can only be reliably distinguished from them by genetic analysis or examination of the shape of their spermatozoa. (wikipedia.org)
  • Sarah Gregory] You found that host species show manifestations of illness from the rat lungworm. (cdc.gov)
  • And then there is rat HEV, which is the species Rocahepevirus ratti genotype C1, and it's genetically highly divergent from other HEVs and a number of rodent species can carry rat HEV. (cdc.gov)
  • The fertility rate was reduced significantly in the group with periodontitis . (bvsalud.org)
  • Periodontitis that is induced in rats is not a risk factor for preterm birth or low birthweight . (bvsalud.org)
  • This study aimed to investigate the molecular mechanisms of protective effects of curcumin against cisplatin-induced kidney inflammation and apoptosis in rats. (thieme-connect.com)
  • Pre-treatment with curcumin significantly ameliorated inflammation and apoptosis induced by cisplatin. (thieme-connect.com)
  • A synthetic catalase-superoxide dismutase mimetic (EUK-134) significantly blunted lung inflammation and respiratory function decline confirming the role of oxidant imbalance. (cdc.gov)
  • Group I as control, Group II as sham-treated with WS by 62.5mg/g per diet, Group III fructose-fed rats received 10%W/V fructose, and Group IV fructose- and WS-fed rats. (nih.gov)
  • Rats were fed for 6 weeks the following diets, that is, control, 0.5% quercetin, 1.0% methionine, and 1.0% methionine plus 0.5% quercetin diets. (hindawi.com)
  • At young adulthood, behavior was tested in the open field, and no difference was observed between treated and control rats. (akjournals.com)
  • Group 1 (control) were given clean drinking water and rat chow, group 2 were given intra-muscular (IM) quinine injection 10mg/kg body weight + water + rat chow. (researchgate.net)
  • Lymphocyte numbers were significantly higher in the control group than in the dust treated group. (cdc.gov)
  • No specific precipitating antibodies were noted on counterimmunoelectrophoresis of random serum samples from control and exposed rats. (cdc.gov)
  • In the first experiment, 62% (15/24) of 6-OHDA pre-treated rats and 45% (11/24) of those receiving ascorbic acid as control solution progressed to motor limbic seizures evolving to SE, after the administration of pilocarpine. (scielo.br)
  • The aim of this study was to investigate the effect of dietary thylakoids on the gut microbiota composition, mainly the taxa of lactobacilli and bifidobacteria, in rats fed either a thylakoid-enriched diet or a control diet for 10 d. (lu.se)
  • Food intake was significantly decreased in the thylakoid-fed rats compared with the control-fed rats over the 10-d study. (lu.se)
  • An oral glucose tolerance test after 10 d of thylakoid- or control-food intake resulted in significantly reduced plasma insulin levels in the thylakoid-fed rats compared with the control-fed rats, while no difference was observed for blood glucose levels. (lu.se)
  • Analysis of gut bacteria showed a significant increase of lactobacilli on the ileal mucosa, specifically Lactobacillus reuteri, in the rats fed the thylakoid diet compared with rats fed the control diet, while faecal lactobacilli decreased. (lu.se)
  • The changes in gut microbiota in NAFLD rats are mainly reflected in their diversity and composition, while QHD treated rats restored these changes. (frontiersin.org)
  • Studies have shown that rat HEV failed to infect rhesus monkeys and pigs, suggesting that rat HEV is restricted to its natural host ( 6 , 8 ). (cdc.gov)
  • In the present article, we perform cortical type analysis of the neocortex of adult rats, Rhesus macaques, and humans to propose hypotheses on homology of cortical areas applying the principles of the Hypothesis on the Dual Origin of the Neocortex. (springer.com)
  • Immunohistochemistry was used to examine the reactivity of microglia (ionized calcium-binding adapter molecule 1, IBA-1) and astroglia (glial fibrillary acidic protein, GFAP), as well as blood vessel density (rat endothelial cell antigen 1, RECA-1) and albumin extravasation. (lu.se)
  • Direct antigen detection kits (ie, rapid antigen tests [RATs], strep screens) have been proposed to allow immediate diagnosis and prompt administration of antibiotics. (medscape.com)
  • We tested the serum samples for the presence of HEV IgG and IgM antibodies by using an ELISA based on rat HEV-like particles, as described ( 3 ). (cdc.gov)
  • Serum homocysteine was significantly increased after methionine treatment and decreased after the addition of quercetin. (hindawi.com)
  • It is concluded that quercetin reduces serum homocysteine by increasing remethylation and transsulfuration of homocysteine in rats exposed to a methionine-enriched diet. (hindawi.com)
  • How the rats detect vertical surfaces and what environmental stimulus trigger this behavior still remains a problem to be solved. (bvsalud.org)
  • Furthermore, silibinin significantly decreased AOM-induced inducible nitric oxide synthase- and cyclooxygenase-2-positive cells in colon tissues. (nih.gov)
  • Effects of exercise training on in vivo insulin action in individual tissues of the rat. (jci.org)
  • Bolus intravenous doses (5 mg/kg) of radiolabeled rosuvastatin, pravastatin, and simvastatin were administered to rats, and initial uptake clearance (CL uptake ) in various tissues was calculated. (aspetjournals.org)
  • Signaling between neurons was also better in the treated rats, suggesting enhanced learning and memory function. (medicalnewstoday.com)
  • Demonstration of inflammatory cell population changes in rat lungs in response to intratracheal instillation of spring wheat dust using lung enzymatic digestion and centrifugal elutriation. (cdc.gov)
  • The response of inflammatory cells in the lung and peripheral blood was determined during short term time course exposures to inhaled grain dust in specific pathogen free Lewis-rats. (cdc.gov)
  • Significantly elevated numbers of granulocytes were present in the dust exposed lung and airways surfaces as determined by bronchoalveolar lavage. (cdc.gov)
  • The 13C retained in the lung at 0.5 h postexposure was about 70% less than predicted by rat deposition models for ultrafine particles, and did not change significantly during the 24-h postexposure period. (cdc.gov)
  • We also represent the topological distribution of cortical types in simplified flat maps of the cerebral cortex of monotremes, rats, and primates. (springer.com)
  • The present study was conducted to evaluate the hepatoprotective effects of the Centella asiatica extract in carbon tetrachloride-induced liver injury in rats. (ijpsonline.com)
  • A study conducted in rats found that the administration of Centella asiatica leaf powder prevented mortality rate due to gross protein deficiency, increased blood protein nitrogen and prevented fatty infiltration of liver [ 2 ]. (ijpsonline.com)
  • The present study reports the protective effects of a water-dispersable extract of Centella asiatica leaves in CCl 4 -induced liver injury in rats. (ijpsonline.com)
  • Separate pre-treatments with STS (150 mg/kg), 4MP (100 mg/kg) and l-NAC (4 x 400 mg/kg) all dramatically reduced blood CN levels, but only l-NAC significantly protected GSH levels in both the liver and the cochlea. (cdc.gov)
  • The objective of our pilot study was to determine whether ultrafine elemental carbon particles translocate to the liver and other extrapulmonary organs following inhalation as singlet particles by rats. (cdc.gov)
  • The mRNA expression of methionine synthase was significantly increased after methionine or methionine plus quercetin supplementation, while its enzymatic activity was significantly increased after methionine plus quercetin supplementation. (hindawi.com)
  • The mRNA expression and enzymatic activity of cystathionine β -synthase and cystathionine γ -lyase were upregulated after quercetin, methionine, or quercetin plus methionine treatment and a more significant increase was observed for hepatic cystathionine β -synthase in the methionine plus quercetin treated rats, suggesting an interaction between methionine and quercetin. (hindawi.com)
  • On examination of enzymatic digestion of rat lungs a significantly higher number of neutrophils was found in the dust exposed animals at both 6 and 24 hours than was seen for the controls. (cdc.gov)
  • We show that areas in the outer rings of the neocortex have comparable laminar elaboration in rats and primates, while most 6-layer eulaminate areas in the innermost rings of primate neocortex lack homologous counterparts in rats. (springer.com)
  • When rats are put into a new environment, they normally spend a lot of time randomly exploring before settling into predicable patterns of activity. (medicalnewstoday.com)
  • However, it is not known whether animals other than rats are susceptible to rat HEV. (cdc.gov)
  • Rat hepatitis E virus (HEV), a member of genus Hepevirus in the family Hepeviridae , was first detected in Norway rats in Germany in 2010 ( 1 , 2 ). (cdc.gov)
  • Phylogenetic analysis of rat hepatitis E virus (HEV) isolated from Asian musk shrews ( Suncus murinus ) in Zhanjiang City, China. (cdc.gov)
  • When an adult rat gains access to a new environment the amount and intensity of exploratory behavior is related to the amount of similarity of such environment to familiar ones (Montgomery, 1955). (bvsalud.org)
  • Previous studies have demonstrated that curcumin at a dose of 100 mg/kg orally in mice and 60 mg/kg in rats reduced concentration of tumor necrosis factor (TNF)-α and inhibited oxidative stress in cisplatin-induced nephrotoxicity [ 7 ] [ 8 ]. (thieme-connect.com)
  • Whisker deprivation weakens excitatory layer 4 (L4) inputs to L2/3 pyramidal cells in rat primary somatosensory (S1) cortex, which is likely to contribute to whisker map plasticity. (jneurosci.org)
  • Sanides developed this hypothesis based on his observations of the cortex of humans, non-human primates, cats, and rats and on the works of Raymon Dart ( 1934 ) on the cortex of reptiles and Andrew A. Abbie ( 1940 , 1942 ) on the cortex of marsupials and monotremes [see Table 2 in García-Cabezas et al. (springer.com)
  • In contrast, the concentration of plasma total free glutathione (GS increased significantly in the 0 Se animals. (usda.gov)
  • None of these markers were significantly upregulated in animals treated with L-DOPA-ropinirole or ropinirole alone. (lu.se)
  • Rats are territorial animals which use their territory to get food, water, nest material and sexual mates, being guided in their activities by environmental cues (Fowler, 1966). (bvsalud.org)
  • To determine whether Asian musk shrews are a reservoir for rat HEV, we examined 260 shrews (112 males, 148 females) that were trapped in Zhanjiang City during December 2011-September 2012. (cdc.gov)
  • Males are not significantly larger than females. (wikipedia.org)
  • All rats were sacrificed at 16 weeks of age, and colon samples were evaluated for ACF, followed by proliferation, apoptosis, and inducible nitric oxide synthase and cyclooxygenase-2, by immunohistochemistry and/or immunoblotting. (nih.gov)
  • Conclusions These data indicate that curcumin has nephroprotective properties against cisplatin-induced kidney damage in rats and this effect is associated with its anti-inflammatory and anti-apoptosis profiles, in addition to its antioxidant. (thieme-connect.com)
  • Moreover, knocking down BDNF partially reversed esketamine-mediated activation of the mBDNF/TrkB/PI3K signaling pathway and inhibition of neuronal apoptosis in propofol-induced rats. (degruyter.com)
  • Our data suggest that WS normalizes hyperglycemia in fructose-fed rats by reducing inflammatory markers and improving insulin sensitivity. (nih.gov)
  • Whole body insulin sensitivity was significantly increased in ET. (jci.org)
  • The red rock rat is a rat-sized murine rodent. (wikipedia.org)
  • Don't put it off any longer, dump your rat tail hairdo and bring a new form of radical rodent into your life with the soul nourishing Lib Tech Jamie Lynn Rat Tail FundaMENTAL C3 BTX Snowboard. (evo.com)
  • First, a dose-response study revealed that all doses of AET tested (5, 10, 20 mg/kg) significantly increased locomotor activity. (erowid.org)
  • A solution containing ethanol and 2,4,6-trinitrobenzenesulfonic acid (TNBS) was instilled into the distal colon in the rat (at a dose of 100 mg/kg) to set up UC rat model. (wjgnet.com)
  • In conclusion, T-2 toxin did not significantly affect basic nervous system functions at this dose. (akjournals.com)
  • The Behavioral Pattern Monitor, which quantifies locomotor and investigatory responses of rats, was used to characterize the effects of AET in a paradigm that distinguishes between the effects of traditional hallucinogens, amphetamine-like stimulants, and MDMA-like drugs. (erowid.org)
  • After 10 d treatment, all rats were sacrificed simultaneously. (wjgnet.com)
  • Intracerebral disulfide HMGB-1 mimicked the effect of the stressor, because microglia isolated from HMGB-1-treated rats expressed exaggerated NLRP3 and proinflammatory cytokine expression after LPS treatment, whereas fully reduced HMGB-1 had no effect. (jneurosci.org)
  • A rat model of propofol-induced brain injury was established with or without the treatment of esketamine. (degruyter.com)
  • With no current effective treatment, possibility of range expansion by the rat lungworm, in combination with increased consumption of raw or undercooked food, will increase the likelihood of infections. (cdc.gov)
  • Endurance exercise did not significantly affect sorbitol levels. (hindawi.com)
  • The size, calcification ratio and mechanical endurance of calluses increased significantly (p (bl.uk)
  • Co-exposure induced a significantly greater respiratory function decline compared to individual exposure. (cdc.gov)
  • Before in vivo experiment, cadavers were used to calibrate the system so that it was able to produce stable and repeatable transverse fracture in rats' femurs. (bl.uk)
  • First, to date, evidence on monoaminergic differences between high and low P rats is based largely on ex vivo, whole-tissue measures of DA and 5-HT rather than extracellular measures of transmitter release. (aspetjournals.org)
  • The results showed that a total of 278 proteins with significant changes were identified by quantitative proteomic analysis, of which 118 proteins were significantly upregulated and 160 proteins were significantly downregulated in myocardial tissue. (frontiersin.org)
  • The results showed that all values obtained were significantly greater in the infected group. (bvsalud.org)
  • Here, we used ultra-high performance liquid chromatography-tandem quadrupole time-of-flight mass spectrometry (UPLC-Q-TOF/MS) to analyze DOX-induced HF in rats, to explain the toxicological pathways of DOX to the heart, especially the combined proteomic technology, to provide more information for the study of its pathogenesis. (frontiersin.org)
  • Rats with unilateral 6-hydroxydopamine lesions were treated with therapeutic-like doses of L-DOPA (6 mg/kg), an equipotent L-DOPA-ropinirole combination (L-DOPA 3 mg/kg plus ropinirole 0.5 mg/kg), or ropinirole alone. (lu.se)
  • Post hoc comparisons showed that spironolactone at doses of 50, 100, and 200 mg/kg significantly reduced alcohol intake ( P s = .007, .002, and .0001, respectively). (medscape.com)
  • Co-author Gary Lynch notes that the treated rats had developed strategies for exploration, and they demonstrated a better memory of the environment. (medicalnewstoday.com)
  • However, the rats that received ampakine had established predictable patterns by the second day in the new arena, while the placebo group continued their random exploration. (medicalnewstoday.com)
  • O'Shaughnessy and Moreau de Tours administered large amounts of hashish extracts to mice, rabbits and rats without producing any lethal effects. (unodc.org)
  • Additionally, AET significantly decreased measures of investigatory behavior. (erowid.org)
  • Exploratory behavior seems to be limited by thigmotaxis, a tendency to remain close to vertical surfaces the probable function of which is to protect rats from predation. (bvsalud.org)
  • We attempted to assess the influence of thigmotaxis on the exploratory behavior of rats, leaving open the question of its sensory basis. (bvsalud.org)
  • The aim of the present study was to investigate, and compare with pravastatin and simvastatin, the tissue-specific distribution of rosuvastatin in rats. (aspetjournals.org)
  • Initially, they studied rodents and found that spironolactone reduced binge drinking in mice and reduced self-administration of alcohol in rats without adversely affecting food or water intake or causing motor or coordination problems. (medscape.com)
  • We previously showed that rat HEV infection frequently occurs in wild rats in Zhanjiang City, Guangdong Province, China ( 9 ). (cdc.gov)
  • Fennel honey, propolis and bee venom significantly improve the immune response of rats to staphylococcal infection. (greenmedinfo.com)
  • As public awareness of the rat lungworm increases, we stand a better chance at preventing human infection. (cdc.gov)
  • Meanwhile, hepatic ratio of S-adenosylmethionine to S-adenosylhomocysteine was significantly decreased in response to methionine supplementation and normalized after the addition of quercetin. (hindawi.com)
  • Cmin∞ ${C}_{min}\hat{\infty }$ imatinib was found to be significantly associated with BCR-ABL ratio. (degruyter.com)
  • E4 significantly prevented the reduction of the b-wave and oscillatory potential amplitudes and retinal cell loss and maintained the Bcl-2/Bax and Bcl-xL/Bax ratio balances in GK rats. (molvis.org)
  • Museum of Natural History, about her article on the rat lungworm expansion in North America. (cdc.gov)
  • In the second experiment, the frequency of seizures in the model's chronic phase did not significantly change between groups. (scielo.br)
  • Knowledge and practice performance of the videotape group was better than the lecture group and in both groups the improvement of knowledge scores after training was significantly higher than that of practice scores. (who.int)
  • To this end, power output was measured in rat cardiac myocyte fragments that expressed {approx}12% {alpha}-MyHC and in myocyte fragments that expressed {approx}0% {alpha}-MyHC, as determined in the same cells by SDS-PAGE analysis after mechanical experiments. (umsystem.edu)
  • Title : Thalamocortical Dysfunction and Thalamic Injury after Asphyxial Cardiac Arrest in Developing Rats Personal Author(s) : Shoykhet, Michael;Simons, Daniel J.;Alexander, Henry;Hosler, Christina;Kochanek, Patrick M.;Clark, Robert S. B. (cdc.gov)
  • The rats were then put on stock diet for 7 from the local market and dried in a hot days prior to the experiment. (who.int)
  • In a first experiment, we examined the hypothesis that rats avoid the open arms of an elevated plus-maze because, in such places, they cannot stay close to vertical surfaces (Treit and Fundytus,1989). (bvsalud.org)
  • Motivation to explore a novel environment appears around the 21st day of life, three or four days after the rats' eyes open, but even at this early age, pups are responsive to thigmotaxis stimuli. (bvsalud.org)