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  • biochemical
  • After treatment with Livartho drug (206.6 mg/kg body weight) once daily for 16 days to paracetamol treated rats shows significantly lowered the afore mentioned biochemical parameter whereas protein and albumin levels were increased along with significant increased above mentioned antioxidant enzymatic parameters. (omicsonline.org)
  • toxicity
  • Here we investigated the subacute toxicity of 4-week repeated oral doses of YMJ in a Crl:CD (SD) rat model according to guidelines established by the Organization for Economic Cooperation and Development (OECD) for the testing of chemicals in accordance with current Good Laboratory Practice regulations [ 9 ]. (hindawi.com)
  • In the current study the developmental toxicity of sodium molybdate dihydrate as a representative of a broad class of soluble molybdenum(VI) compounds, was given in the diet to Sprague Dawley rats in accordance with OECD Test Guideline 414. (rti.org)
  • In conclusion, cyadox was not carcinogenic to rats with the liver and kidney as the target organs, and the side chain may be involved in toxicity and carcinogenicity mediated by QdNOs. (ovid.com)
  • dose
  • These results revealed that a 14-day repeated oral dose of 1,3-DCP was minimally embryotoxic but not teratogenic at a maternal toxic dose (90mg/kg/day), and was not embryotoxic at a minimally maternal toxic dose (30mg/kg/day) in rats. (sigmaaldrich.com)
  • diet
  • One hundred similar rats on a special fatrich diet developed an 80 per cent tumor incidence. (aacrjournals.org)
  • The rat had been on a 12hour light:dark cycle (lights on at 07:00) and had access ad libitum to drinking water and a diet of commercially available cubes for mice (Epol, South Africa). (scielo.org.za)
  • The no-observed-effect-level (NOEL) for carcinogenicity of cyadox fed to rats was 2000 mg/kg diet (132.18-156.28 mg/kg b.w./day). (ovid.com)
  • days
  • Eighty-seven per cent of all tumors appeared after the rats were 540 days of age, and the mean lifespan after a tumor was first observed was 140 days. (aacrjournals.org)
  • human
  • Our rat hepatocytes are prepared using the same careful isolation and cryopreservation techniques as our human lots. (thermofisher.com)
  • potential
  • Although uterine torsion is a rare condition in rats, it should be considered as a potential complication of gestation in animal breeding units. (scielo.org.za)
  • Developmental toxic potential of 1,3-dichloro-2-propanol in Sprague-Dawley rats. (sigmaaldrich.com)
  • To investigate the potential carcinogenicity of cyadox, an antimicrobial agent, four groups of Sprague-Dawley rats (50 rats/sex/group) were fed diets containing cyadox (0, 200, 600 or 2000 mg/kg) for up to two years. (ovid.com)
  • less
  • The animal attendant indicated that he had not noticed any untoward behaviour or sickness in the rat during the previous cage change 48 hours earlier However, about 12 hours before death the rat was less active than usual. (scielo.org.za)