• Twenty-four male Sprague-Dawley rats weighing 240-280 g and aged 7 weeks were housed individually in an animal resources facility in a room at a controlled temperature (20-22.8°C) and under a 12 h light/dark cycle. (hindawi.com)
  • In vivo neural recordings were performed in male Sprague Dawley rats. (dovepress.com)
  • Male Sprague-Dawley rats underwent creation of a previously validated ischemic flap. (nih.gov)
  • r\nMethods: Thirty-six 12-month-old adult female Sprague-Dawley rats were used in this study. (aott.org.tr)
  • Male Sprague-Dawley rats were randomly divided into six groups consisted of 3-5 animals. (scialert.net)
  • Adult male Sprague-Dawley rats, 200-230 g purchased from Faculty of Veterinary Medicine, Universiti Putra Malaysia and acclimatised at the animal house of the Faculty of Medicine and Health Sciences, Universiti Putra Malaysia. (scialert.net)
  • Methods: A rat model (Sprague Dawley) of PS-HypoPT was obtained by the surgical removal of parathyroids at 5 weeks of age and treated with gluconate calcium 1% in drinking water to maintain normocalcemia. (endocrine-abstracts.org)
  • An experimental group of 15 PS-HypoPT rats and 15 healthy Sprague Dawley controls (WT) underwent biochemical testing (serum calcium) and behavioural testing namely Morris Water Maze MWM-to assess spatial learning and memory at 9 weeks of age. (endocrine-abstracts.org)
  • Healthy adult Sprague‑Dawley (SD) male rats were used to establish a control group, sham‑operated group, middle cerebral artery occlusion (MCAO) group, empty virus group and lentivirus group. (spandidos-publications.com)
  • Methods: Female Sprague-Dawley rats underwent BPNI or sham surgery and were evaluated 3, 7, 14, and 30 days post-BPNI (n = 8/group). (lu.se)
  • A total of 72 male Sprague Dawley rats (215±15 g) were randomly divided into three groups (n=24/group): The sham operation, model and exercise intervention groups, with the latter undergoing 4 weeks of swimming training. (iasp-pain.org)
  • Adult male Wistar rats were exposed to predator odor stress in a conditioned place avoidance paradigm and indexed for high (Avoiders) and low (Non-Avoiders) avoidance of predator odor-paired context, or were unstressed Controls. (nature.com)
  • Sixteen virgin female Wistar rats were mated with eight males (2: 1) for approx 12 h to obtain first-generation rats. (fluoridealert.org)
  • Wistar rats) [155], failed to influence food intake during a 1 h ad libitum feeding period, moderate to high doses of CBD (4.4 mg·kg −1 , i.p. [58]. (researchgate.net)
  • METHODS: Male Wistar rats underwent anterior cruciate ligament transection (ACLT) or sham operation of the right knee. (usp.br)
  • The laparotomy was preformed under general anesthesia (Xylazin and Ketamin) using Wistar rats. (nel.edu)
  • Materials and Methods: Twenty Wistar rats underwent enterotomy, ileoileal anastomosis and divided into four groups (A: complete anastomosis-no FG, B: complete anastomosis-FG, C: incomplete anastomosis-no FG, D: incomplete anastomosis-FG). (iiarjournals.org)
  • Twenty female Wistar rats with mean body weight of 244 g were used for our study. (iiarjournals.org)
  • CRF by a 7/8 nephrectomy was carried out in male Wistar rats fed with a diet rich in phosphorous (0.9%) and normal calcium (0.6%) for a period of 12 weeks until sacrifice. (bvsalud.org)
  • The fourth group underwent a sham surgery in which no reproductive organs were removed. (sciencedaily.com)
  • Four groups of rats (n = 10) were used, guide cannula was implanted into the PVN and adrenalectomy (ADX) was performed into three groups, a fourth group underwent a sham surgery (Sham group). (bvsalud.org)
  • Methods: MS-818 at 1.0 or 10 mg/kg or the vehicle was intraperitoneally injected into rats daity. (iospress.com)
  • Therefore, TNF-α and IL-1 gene expression on the abdominal aorta of obese and DM rats that went through SG procedure were evaluated.METHODS: Fifteen rats were divided into 3 groups: lean-non-DM rats model (C1 group), obese-DM rats model (C2 group), and obese-DM rats model underwent SG (T group). (researchgate.net)
  • Non-treated ischemic (n=8) animals formed the control group. (erowid.org)
  • This regionally specific protection implies that either the hippocampus undergoes suprathreshold ischemic injury or that mechanisms of ischemic injury vary in different brain regions. (erowid.org)
  • When combined with an HS, an UCCAO is associated with ischemic neuronal injury in the ipsilateral hemisphere of adult rat brain, which can be attenuated by therapeutic hypothermia. (medsci.org)
  • A study has shown that neurons in the ischemic penumbra may undergo apoptosis hours or days after ischemia and alleviating ischemia reperfusion injury is an achievable therapeutic goal in the early intervention of ischemic stroke aimed at limiting the amount of infarction ( 4 ). (spandidos-publications.com)
  • Rats were divided into 3 equal groups and sacrificed in groups of 4 at the 4th, 8t, and 12th weeks postoperatively and the lumbar spine excised en bloc, fixed and decalcified. (aott.org.tr)
  • r\nConclusion: Endogenous estrogen could have an effect on epidural fibrosis formation after lumbar laminectomy in rats. (aott.org.tr)
  • Thirty-eight female rats underwent posterolateral lumbar spinal fusion. (wright.edu)
  • Effects of swimming on pain and inflammatory factors in rats with lumbar disc herniation. (iasp-pain.org)
  • The aim of the present study was to identify the effect of swimming on nerve root pain in rats with lumbar disc herniation (LDH). (iasp-pain.org)
  • Adult male cynomolgus-monkeys and Fischer-344-rats of both sexes were used in a chronic inhalation toxicity study designed to evaluate the nature of the lung response to inhalation of fibrous glass , with respect to the prevailing federal standard. (cdc.gov)
  • Adult rats were injected with LPS and GTE was administered intra-gastrically at 2, 8, 26 and 32 hours post-injection. (nature.com)
  • Ocular inflammation was induced in adult rats by injecting 1 mg/kg LPS into the left footpad. (nature.com)
  • The researchers use several surgical approaches that are actually used for women who undergo oophorectomy, hysterectomy, or both. (sciencedaily.com)
  • Objective: The aim of this study was to examine the effect of oophorectomy in the formation of epidural fibrosis in a rat laminectomy model. (aott.org.tr)
  • Bilateral oophorectomy was performed on the 18 rats in the oophorectomized group. (aott.org.tr)
  • Three weeks after oophorectomy, rats in both groups underwent complete bilateral laminectomy at the L2 and L3 vertebral levels. (aott.org.tr)
  • The aim of this study was to investigate the protective effect of necrostatin-1 on myocardial tissue of acute myocardial infarction (AMI) rats and to provide a basis for necrostatin-1 for the treatment of acute myocardial infarction. (geneticsmr.com)
  • Patients with known coronary artery disease undergoing surgery should be monitored for evidence of myocardial ischemia and provided therapy to prevent and treat ischemia in the perioperative period. (medscape.com)
  • We experimentally induced neuropathic pain - a type of chronic pain caused by damage or disease of nerves - in the rats by loosely constricting the sciatic nerve in the thigh. (iflscience.com)
  • As we expected, the neuropathic pain due to sciatic nerve constriction continued for another four weeks in the rats that had received the saline control. (iflscience.com)
  • A group of sham control rats underwent surgery, but the sciatic nerve was not constricted. (iflscience.com)
  • A rat model of SNI was established, with the injury group subjected to compressive injury of the right sciatic nerve exposed at the midpoint of the thigh and the sham surgery group undergoing the same surgical procedure. (techscience.com)
  • My colleagues and I have just published a new paper in the Proceedings of the National Academy of Sciences USA showing that morphine can persistently exacerbate pain in rats. (iflscience.com)
  • We found that rats with HDAC5 overexpression in DS responded faster and chose higher value reward more often during the first block of trials but were less able to reverse those contingencies in the second block of trials. (jneurosci.org)
  • In this study, we found that local BoTA preconditioning yielded significant protection against IR injury in a rat musculocutaneous flap model. (hindawi.com)
  • In this study, a rat model of wound ischemia was used to test the hypothesis that HBO enhances wound healing by modulating hypoxia-inducible factor-1alpha (HIF-1alpha) signaling. (nih.gov)
  • Rat posterolateral arthrodesis model. (wright.edu)
  • In the present study, we showed that LPS could be used to establish a retinal inflammatory model on SD rats as well. (nature.com)
  • The aim of this study was to evaluate the effects of PTH deprivation on CNS in an animal model (rat) of post-surgical hypoparathyroidism, by a cognitive/behavioural assessment approach. (endocrine-abstracts.org)
  • These results suggested that HSP90β is involved in the process of cerebral ischemia‑reperfusion injury in rats and that inhibition of HSP90β expression increases EAAT2 levels, conferring a neuroprotective effect in MCAO model rats. (spandidos-publications.com)
  • Inspired by this surface, researchers reporting in ACS Nano have developed a treatment for osteoarthritis that enhances lubrication and reduces friction and inflammation in a rat model of the disease. (ptproductsonline.com)
  • In the present study, epigastric arteries of kidney transplant recipients, a rat model of VC, and an in vitro model of VC exhibiting catalase (Cts) overexpression were analysed. (bvsalud.org)
  • In the rat model, advanced aortic VC concurred with lower levels of the H2O2-scavenger glutathione peroxidase 3 compared to controls. (bvsalud.org)
  • We studied the effect of a hybrid compound, GGN1231 (derived from losartan in which a powerful antioxidant was attached), on the prevention of cardiovascular damage, cardiac hypertrophy, and fibrosis in a rat model of severe chronic renal failure (CRF). (bvsalud.org)
  • The spontaneously hypertensive rat (SHR) is the most widely studied animal model of essential hypertension. (jci.org)
  • The rats were randomly divided into the model group and necrostatin-1 low-dose and high-dose groups. (geneticsmr.com)
  • The results demonstrated that, in the model group, the threshold of hind paw withdrawal was decreased, and that the sPLA2 expression, IL-6 and TNF-α content, PLA2, IL-6 and TNF-α mRNA and NF-κBp65 protein expression levels in the nucleus pulposus were increased. (iasp-pain.org)
  • In the exercise intervention group, the hind paw withdrawal threshold increased and the TNF-α and IL-6 content, sPLA2 expression and PLA2, IL-6 and TNF-α mRNA and NF-κBp65 protein expression levels were decreased from day 14 following surgery, and the apoptotic nucleus pulposus cells were decreased from day 7 following surgery, as compared with the model group. (iasp-pain.org)
  • Three days postoperatively, five rats from group A were sacrificed. (thieme-connect.de)
  • Microangiography was performed on five rats in Group A, revealing neovascularization of the hydroxyapatite. (thieme-connect.de)
  • Pregnant rats were divided into two experimental groups (control and fluoride-supplemented), each containing five rats. (fluoridealert.org)
  • Anesthetized (isoflurane) Long-Evans rats underwent unilateral circumlimbal suture implantation while the fellow eyes served as untreated controls ( n = 15). (arvojournals.org)
  • We therefore investigated the impact of global brain hypoxia-ischemia on the thalamic circuit function in the somatosensory system of young rats. (cdc.gov)
  • Finally, intra-CeA infusion of tetrodotoxin produced thermal hyperalgesia in unstressed rats and blocked the anti-hyperalgesic effect of systemic CRFR1 antagonist in stressed rats. (nature.com)
  • This study examines rat models of penetrating ballistic-like brain injury (PBBI) and HX+HS to assess whether the blood levels of brain and systemic response biomarkers phosphorylated neurofilament-heavy protein (pNF-H), neurofilament-light protein (NF-L), αII-spectrin, heat shock protein (HSP70), and high mobility group box 1 protein (HMGB1) can distinguish pTBI from systemic insults and guide in pTBI diagnosis, prognosis, and monitoring. (quanterix.com)
  • The time taken for fluorescence to peak in the systemic circulation was 20 +/- 1 min in the treated group in contrast with 15 +/- 1 min in the control group. (blogspot.com)
  • We previously demonstrated that GTE is a potent anti-inflammatory and anti-oxidative agent in the eye, alleviating the endotoxin-induced acute anterior uveitis and sodium iodate-induced retinal degeneration in rats 13 , 14 , suggesting a potential treatment for ocular diseases. (nature.com)
  • The basic level of hydroxyl radicals and singlet oxygen were measured and the effects of antioxidants on their levels were studied in the tail of living anaesthetized rats after acute postoperative pain. (nel.edu)
  • The animals in the sham group underwent surgical procedures except partial IR. (hindawi.com)
  • A sham group ( n = 8) received the same procedure except that the suture was loosely tied. (arvojournals.org)
  • The experimental subjects (rats) were assigned to one of four treatments: to Sham group saline was given, to group ADX saline was applied, the group 8-OH-DPAT was provided with 8-OH-DPAT (5-HT 1A agonist) and the pretreated group received 5-HT 1A antagonist WAY100635 + 8-OHDPAT. (bvsalud.org)
  • The rats in the IR group underwent 45 min partial kidney ischemia, and the animals in the IPC + IR group underwent two 5 min cycles of partial kidney ischemia followed by 10 min reperfusion and partial kidney ischemia for 45 min. (hindawi.com)
  • On histologic examination, new bone formation was confirmed in 15 of the remaining 20 rats in Group A, and in three of the 20 rats in Group B. These experiments demonstrated that the prefabricated vascularized periosteal graft, which has good osteogenic capacity, could be carried out using a fascial flap transfer. (thieme-connect.de)
  • To make this discovery, Baker and colleagues conducted experiments involving three groups of rats. (sciencedaily.com)
  • Researchers in the Arizona State University Department of Psychology have found rats that underwent the surgical removal of the uterus with ovaries left intact had a memory deficit, suggesting the uterus might have functions beyond reproduction. (sciencedaily.com)
  • The rats were divided into four groups based on the type of menopause surgical intervention. (sciencedaily.com)
  • The surgical removal of just the uterus had a unique and negative effect on working memory, or how much information the rats were able to manage simultaneously, an effect we saw after the rats learned the rules of the maze" said Stephanie Koebele, ASU psychology graduate student and first author on the paper. (sciencedaily.com)
  • In this study, we performed an ileoileal anastomosis on rats using a specific surgical technique and applying FG on the suture line. (iiarjournals.org)
  • "We thought that if any group is able to change their hippocampus through language learning, it would be the prospective interpreters within the Armed Forces, as they undergo intensive language learning of 350-400 words a week. (lu.se)
  • Once the neuropathic pain was fully established 10 days later, the rats received morphine or saline control (salt water) for five days via injections under the skin. (iflscience.com)
  • Rats were divided into two groups: normal saline control and pantroprazole, which was administered by daily intraperitoneal injections. (wright.edu)
  • Rats were trained to self-administer oxycodone (8 days, training phase), after which we examined oxycodone self-administration behaviors for an additional 14 days under three conditions in male and female rats: short access (ShA, 1 h/d), long access (LgA, 6 h/d), and saline self-administration. (frontiersin.org)
  • Histological section of the eye showed that LPS induced substantial accumulation of infiltrating cells in the vitreous humor 48 hrs after injection (n = 7) (Fig. 1b ), which was not detected in the saline-injected rats (n = 7, Fig. 1a ). (nature.com)
  • To understand the mechanism underlying death receptor- and ER-mediated apoptosis during rat liver regeneration, we used the Rat Genome 230 2.0 Array to determine the changes in gene expression. (geneticsmr.com)
  • Hepatocyte death by apoptosis occurs in alcoholic fatty liver and has been demonstrated in rats and mice after ethanol feeding. (medscape.com)
  • This study delves into the intricate exploration of potential toxic effects resulting from subchronic exposure to fenpropathrin (FNP) on the reproductive system of male SD rats. (medworm.com)
  • The study involved a cohort of sixty male SD rats (six groups): vehicle control, CUR, Cs.CUR.NPs, FNP, and two combination groups (FNP with CUR or Cs.CUR.NPs). (medworm.com)
  • At the end of the 4-mo experimental period, nine randomly chosen male rats (F1) were sacrificed, and the kidneys were removed for the histological and lipid peroxidation examinations. (fluoridealert.org)
  • After the lactation period, the young male rats (second-generation male rats [F2]) were also treated similarly for 4 mo. (fluoridealert.org)
  • We asked whether biological sex contributes to behaviors comprising self-administration of the prescription opioid oxycodone in rats, and we calculated the relative contribution of these behavioral measures to reinstatement in male and female rats. (frontiersin.org)
  • Both male and female rats in LgA and ShA conditions escalated oxycodone intake to a similar extent. (frontiersin.org)
  • In addition, both male and female offspring of rats exposed to stress showed a more rapid acquisition of fear relative to the descendants of the control group. (jpost.com)
  • Rectangular flap (6 × 1.5 cm) was created on the right hemiabdomen of each rat using the costal margins as the superior border (Figure 1 ). (hindawi.com)
  • In Group B, the fascial flap was immediately wrapped around the hydroxyapatite cube. (thieme-connect.de)
  • The researchers then injected drug-loaded HA-MPC particles into the knee joints of rats with early-stage osteoarthritis. (ptproductsonline.com)
  • In two models of partial renal IR with and without ischemia preconditioning (IPC) and using Mas receptor (MasR) blockade, A779 or its vehicle, the renal vascular responses to angiotensin II (Ang II) administration in two-kidney-one-clip (2K1C) hypertensive rats were determined. (hindawi.com)
  • These data revealed the important role of MasR after partial kidney IR in the responses of RBF and RVR to Ang II administration in 2K1C hypertensive rats. (hindawi.com)
  • Genetic isolation of a region of chromosome 8 that exerts major effects on blood pressure and cardiac mass in the spontaneously hypertensive rat. (jci.org)
  • Chronic inhalation toxicity of fibrous glass in rats and monkeys. (cdc.gov)
  • This experiment was designed to investigate the lipid peroxidation and histological effects of chronic fluorosis on first- and second-generation rat kidney tissues. (fluoridealert.org)
  • To induce chronic intraocular pressure (IOP) elevation in rat eyes by circumlimbal suture. (arvojournals.org)
  • Circumlimbal suture provides a simple and cost-effective way to induce mild chronic ocular hypertension in rat eyes. (arvojournals.org)
  • It was found that the plasma fluoride and kidney TBARS levels of fluoride-supplemented F1 and F2 rats were higher than controls. (fluoridealert.org)
  • This approach is designed to impede aqueous outflow and has been used in rats, 11 mice, 12 and nonhuman primates. (arvojournals.org)
  • DNA adducts of propylene oxide are formed in various organs of mice, rats and dogs. (who.int)
  • In this study, we tested this hypothesis by examining the mechanoenergetic response of the atrophied LV to RV hypertrophy in rats treated with monocrotaline. (frontiersin.org)
  • AMI rats (45) were established by ligating the anterior descending branch of the left coronary artery. (geneticsmr.com)
  • We measured pain in the rats by assessing their hind paw sensitivity to a poke from a plastic filament that is not normally painful. (iflscience.com)
  • The rats in the control groups underwent the same procedure without NaF supplementation. (fluoridealert.org)
  • Before and 10 days after the SG procedure, rats' body weight and fasting blood glucose (FBG) were measured. (researchgate.net)
  • Jericho, the centre of tors and fat sand rats of the species Psam- the study area, is between 260-400 m be- momys obesus are the natural animal low sea level. (who.int)
  • We then recorded neural correlates from dorsolateral striatum (DLS) as rats performed two reward-guided choice tasks, in which we manipulated either the size of or delay to reward. (jneurosci.org)
  • Thirty rats were randomly assigned to sham, PBBI, HS+HX, and PBBI+HS+HX groups. (quanterix.com)
  • The research team used female rats to systematically test the role of the uterus and ovaries in learning and memory. (sciencedaily.com)
  • As in previous studies, they again exposed female adolescent rats to minor stress involving changes in temperature and routine for a week. (jpost.com)
  • Forty female rats were distributed equally into the following groups: control (CG), alcohol+stress+ligature (ASLG), stress+ligature (SLG), alcohol+ligature (ALG), ligature (LG). (bvsalud.org)
  • The BoTA group had higher expression of CD34, HIF-1 α , VEGF, and NF-kB comparing to control group in qRT-PCR analysis. (hindawi.com)
  • A positive control group received meloxicam 6 mg/kg s.c. for antinociceptive evaluation comparisons. (usp.br)
  • The joints of treated rats were more lubricated and had less cartilage destruction, joint friction and inflammation compared with a control group. (ptproductsonline.com)
  • The GLC-82 cells were randomly divided into the ERGIC3i group and the negative control group. (techscience.com)
  • The control group rats (15) underwent the sham operation. (geneticsmr.com)
  • As a control group, the researchers had access to medical and cognition students at Umeå University. (lu.se)
  • The overall intelligence among the prospective interpreters was not higher than that of the control group, but they were distinguished by their exceptional talent for languages. (lu.se)
  • The results from the MRI scanner showed that the language students' brains developed in some parts, while there was no change in the brains of the control group. (lu.se)
  • In several language areas, the thickness of the cerebral cortex increased among the student interpreters compared to the control group. (lu.se)
  • NGF peptide levels retained in the crushed nerves of rats 5 days after surgery and in the culture medium of IMS32 cells, a mouse Schwann cell line, incubated for 24 h with high or low doses of MS-818, were measured by enzyme immunoassay. (iospress.com)
  • Group I was administered with 0.2% zerumbone for 14 days prior to 3 g kg -1 paracetamol administration. (scialert.net)
  • TH nerve terminals surrounding the detrusor decreased in all BPNI groups, whereas VAChT and nNOS terminals decreased 14 and 30 days post-BPNI. (lu.se)
  • In the first day, the animals of ALG and ASLG were exposed to the ingestion of water and 20% alcohol solution (v/v). The animals of ASLG and SLG underwent stress testing through physical restraint for 4 daily hours, during 60 days until their euthanasia. (bvsalud.org)
  • In this report, we describe the construction and hemodynamic characterization of a congenic strain of SHR (SHR-Lx) that carries a defined segment of chromosome 8 from a normotensive strain of Brown-Norway rats (BN-Lx strain). (jci.org)
  • These findings demonstrate that BP regulatory gene(s) exist within the differential chromosome segment trapped in the SHR-Lx congenic strain and that this region of chromosome 8 plays a major role in the hypertension of SHR vs. BN-Lx rats. (jci.org)
  • Purpose: We evaluated the effects of the drug MS-818 (2-piperadino-6-methyl-5-oxo-5,6-dihydro-(7H) pyrrolo-[3,4-d] pyrimidine maleate), a synthesized pyrimidine compound, on regeneration in crush-injured sciatic nerves of rats. (iospress.com)
  • There is some research showing that women who underwent hysterectomy but maintained their ovaries had an increased risk for dementia if the surgery occurred before natural menopause. (sciencedaily.com)
  • Six weeks after surgery, the researchers taught the four groups of rats how to navigate a maze. (sciencedaily.com)
  • The other kinds of surgery did not affect how many mistakes the rats made in the maze. (sciencedaily.com)
  • The rats that underwent the removal of just the ovaries or the removal of the ovaries plus the uterus navigated similar to the group that had the sham surgery. (sciencedaily.com)
  • In addition, this research suggests probiotics may be able to protect the heart in patients undergoing heart surgery and angioplasty. (sciencedaily.com)
  • The apoptotic rate of the nucleus pulposus cells was increased from day 7 following surgery, as compared with the sham operation group. (iasp-pain.org)
  • Here we investigated the anti-inflammatory effect of GTE on lipopolysaccharides (LPS)-induced retinal inflammation in rats and explored the underlying mechanism. (nature.com)
  • Conversely, the treatment up-regulated inflammatory enzyme activities, TNF-alpha levels and gene expression of NOS2 and IFN-gamma (23 and 7 fold, respectively), and of FIZZ1 and YM1 (8 and 2 fold) when compared with the untreated group. (blogspot.com)
  • Axonal injury-linked biomarkers pNF-H and NF-L serum levels in PBBI groups were higher than those in sham and HX+HS groups at D1 and D2 post-injury. (quanterix.com)
  • This study aimed to evaluate the effects of TQ on spatial memory and hippocampal long-term potentiation (LTP) in rats with thioacetamide (TAA)-induced liver injury and hepatic encephalopathy. (magiran.com)
  • The aim of the study was to demonstrate that direct measurement of hydroxyl radicals and singlet oxygen in the tail of living rats is possible. (nel.edu)
  • This study aimed to investigate whether fibrin glue (FG) (a fibrin sealant containing human factor XII and fibrinogen) has a positive effect on the healing and the integrity of the ileoileal anastomosis in rats. (iiarjournals.org)
  • It was confirmed in this study that there was a decrease of TNF-α in the obese and DM rats who underwent SG compared to the obese and DM rats group. (researchgate.net)
  • To address this issue, we examined the role of dorsal striatal HDAC5, a class II HDAC, in reward-guided decision-making and associated neural encoding in rats. (jneurosci.org)
  • Here, we expanded on these functions and found that overexpression of HDAC5 produced faster and more automatic behavior, and related changes in dorsolateral striatal neural firing in rats performing a value-based decision-making task. (jneurosci.org)
  • At least 11 weeks after weaning, thirty selected F1 rats/sex/ group were bred within their respective treatment groups to produce F2 litters, following the same regime. (europa.eu)
  • The remaining 45 rats were sacrificed 5 weeks postoperatively. (thieme-connect.de)
  • The P1 generation was exposed for at least 10 weeks prior to mating within their respective treatment groups, and allowed to deliver and rear their offspring until weaning (postpartum day 25). (europa.eu)
  • But for the rats that had received morphine, the neuropathic pain continued for 10 weeks. (iflscience.com)
  • Rats underwent the same exposure for 72 weeks. (cdc.gov)
  • Rats self-administered either cocaine or nicotine with contingent cues for weeks, and were then divided into two groups. (vu.nl)
  • Histological examinations of rat brain after 3-week icEEG intracerebral electroencephalography (icEEG) recordings were performed. (dovepress.com)
  • These rats were identified as pregnant and included in this experiment. (fluoridealert.org)
  • The pregnant rats in the fluoride-supplemented group were exposed to 30 mg/L sodium fluoride (NaF) in commercial drinking water containing 0.07 mg/L NaF throughout the gestation and the lactation periods. (fluoridealert.org)
  • In previous studies, they found that exposing rats to stress during adolescence, before they ever become pregnant, causes behavioral changes among their direct offspring when the latter reach adulthood. (jpost.com)
  • EGEEA and EGEE for pregnant rats and humans. (cdc.gov)
  • The Effect of Proton Pump Inhibitors on Bone Formation in a Rat Spinal" by Kevin Sonn, Stephen Wallace et al. (wright.edu)
  • By contrast, for nicotine seeking, the retrieval group exhibited resistance to extinction, an effect that persisted on the spontaneous recovery test. (vu.nl)
  • The effect of laparotomy on hydroxyl radicals, singlet oxygen and antioxidants measured by EPR method in the tails of rats. (nel.edu)
  • The objective of this research was to evaluate the effect of 5HT1A receptor stimulation of the hypothalamic paraventricular nucleus (PVN) on food intake and microstructural analysis in adrenalectomized rats. (bvsalud.org)
  • The group treated with the antibiotic had decreased levels of leptin (a protein hormone that plays a key role in appetite and metabolism), which resulted in smaller heart attacks, and improved recovery of mechanical function as compared to the group fed a standard diet. (sciencedaily.com)
  • Like those fed the antibiotic, these rats also had decreased leptin levels, resulting in smaller heart attacks and greater recovery of mechanical function as compared to the first group. (sciencedaily.com)
  • However, pNF-H and NF-L levels in PBBI+HX+HS groups were not different than their PBBI counterparts. (quanterix.com)
  • At D1, αII-spectrin levels in the HX+HS and PBBI+HS+HX groups were higher than the sham groups. (quanterix.com)
  • αII-spectrin levels in the HX+HS group were higher than the PBBI group. (quanterix.com)
  • The treated rats also expressed higher levels of collagen II and aggrecan, two markers of healthy cartilage. (ptproductsonline.com)
  • Hydroxyproline levels were higher in group D compared to C, but did not reach significance (p=0.098). (iiarjournals.org)
  • The findings indicate that the effects of stress on the first-generation mother rat continue to influence her grandchildren on all three levels - behavioral, hormonal and the manifestation of the CFR1 gene. (jpost.com)
  • The three experimental groups were: removal of the uterus with ovaries left intact, removal of the ovaries with uterus left intact and removal of both the uterus and ovaries. (sciencedaily.com)
  • One of the beauties of this experimental design was the sampling of different measures from the same rat, allowing for within-animal comparisons across multiple systems. (sciencedaily.com)
  • Performance comparisons were made using microelectrode recordings from rat cortex and subdural/depth recordings from epileptic patients. (dovepress.com)
  • The classical three-point bending and impact tests were carried out for three rat bone groups: control (SHO), the humerus of animals under the conditions of established osteopenia (OVX), and bones of rats receiving nesfatin-1 after ovariectomy (NES). (mdpi.com)
  • New bone formation identified on microCT imaging of bilaterally fused specimens demonstrated a lower average volume of newly generated bone in the PPI group, but this difference was not significant. (wright.edu)
  • The HFNC failure group was defined as patients with respiratory support upgraded to non-invasive ventilation, endotracheal intubation or death within 48 h, and the indicators for predicting the HFNC failure were analyzed.Results:The failure rate of HFNC was 24.13%(42/174). (bvsalud.org)
  • Tablets is not recommended in patients undergoing haemodialysis (see sections 4.4 and 5.2). (who.int)
  • 0.0001) that was not different significantly between the groups. (hindawi.com)
  • Average fusion scores were significantly lower in the pantoprazole group. (wright.edu)
  • Results: Angiogenesis was significantly higher in group B compared to group A (p=0.019). (iiarjournals.org)
  • We used single neuron recordings and controlled whisker deflections to examine responses of thalamocortical neurons to sensory stimulation in rat survivors of 9 min of asphyxial cardiac arrest incurred on post-natal day 17. (cdc.gov)