• This study investigated the effect of black adzuki bean (BAB) extract on body composition and hypothalamic neuropeptide expression in Sprague Dawley rats (Rattus norvegicus) fed a high-fat diet. (nih.gov)
  • Male Sprague Dawley rats were used for this study and were divided into two equal groups. (biomedcentral.com)
  • Gopalan's team was slated to present 'The effects of diet-induced obesity in male Sprague Dawley rats on blood glucose, ketones and markers of mental and physical fatigue' at the APS annual meeting at Experimental Biology. (news-medical.net)
  • Animals (6-week old male Sprague-Dawley rats) were administered a 60% high-fat diet for 6 weeks and adipocyte isolated from apididymal fat [1]. (thieme-connect.com)
  • differential effects in Sprague Dawley and Brown Norway rats. (cdc.gov)
  • Both the inbred Brown Norway and the outbred Sprague Dawley rat strains were included to study the influence of strain on the detection of toxicity. (cdc.gov)
  • GMA-SS exposure lowered daily sperm production compared to air controls in Sprague Dawley rats, but only in GMA-SS Brown Norway rats also fed the HF diet. (cdc.gov)
  • At week 24, bronchoalveolar lavage cell counts had returned to background levels for GMA-SS exposed Sprague Dawley rats but remained elevated in Brown Norway rats. (cdc.gov)
  • GMA-SS did not affect daily sperm production statistically significantly at this time point, but testicular weights were lowered in GMA-SS Sprague Dawley rats. (cdc.gov)
  • Serum testosterone remained lowered in Sprague Dawley rats fed the HF diet. (cdc.gov)
  • Feeding and metabolic consequences of scheduled consumption of large, binge-type meals of high fat diet in the Sprague-Dawley rat. (bvsalud.org)
  • Our data indicate that the reduced obesity development in rats fed a HF diet may be attributed to the low metabolisable energy density of carbohydrates in the spent turmeric, independent of SCFA-mediated factors. (rsc.org)
  • The goal of the current work is to determine whether long-term third ventricular (3V) infusion of oxytocin into the central nervous system (CNS) is effective for obesity prevention and/or treatment in rat models. (nih.gov)
  • We found that chronic 3V oxytocin infusion between 21 and 26 days by osmotic minipumps both reduced weight gain associated with the progression of high-fat diet (HFD)-induced obesity and elicited a sustained reduction of fat mass with no decrease of lean mass in rats with established diet-induced obesity. (nih.gov)
  • We conclude that long-term 3V administration of oxytocin to rats can both prevent and treat diet-induced obesity. (nih.gov)
  • Western style diet, which contains high levels of fat, is also considered to be one of the main factors in the development of obesity and insulin resistance. (biomedcentral.com)
  • Obesity can increase the risk of high blood sugar (glucose), which may develop into type 2 diabetes and other metabolic disorders if untreated. (news-medical.net)
  • Researchers at Southern Illinois University Edwardsville aimed to learn more about the onset of obesity and its impact on both physical and mental abilities by studying two groups of rats. (news-medical.net)
  • Turning 'bad' fat into 'good': A future treatment for obesity? (sciencedaily.com)
  • If we could get the human body to turn 'bad fat' into 'good fat' that burns calories instead of storing them, we could add a serious new tool to tackle the obesity epidemic in the United States," says study leader Sheng Bi, M.D., an associate professor of psychiatry and behavioral sciences at the Johns Hopkins University School of Medicine. (sciencedaily.com)
  • Firstly, I believe obesity begins with a "scavenger" metabolism that is ruthless at extracting calories from carbohydrates (CHO) and storing them as fat, something that had survival value prior to agriculture but is now disadvantageous with the "western diet" (WD). (kevinmd.com)
  • The child with obesity must eat a different diet. (kevinmd.com)
  • I explain to the parents of the child with obesity that his/her metabolism is too efficient at turning CHO into fat and that the solution is to either remove all CHO from the diet (Banting) or at least restrict it (low GI). (kevinmd.com)
  • Recently I wrote a column for the Guardian criticizing Whole Foods for selling ketchup that contains high-fructose corn syrup, or HFCS, the synthetic sweetener that has been linked to a catastrophic rise in obesity and Type II diabetes. (dankennedy.net)
  • Some people have claimed that high-fructose corn syrup is no different than other sweeteners when it comes to weight gain and obesity, but our results make it clear that this just isn't true, at least under the conditions of our tests," said psychology professor Bart Hoebel, who specializes in the neuroscience of appetite, weight and sugar addiction. (dankennedy.net)
  • For instance, zingerone was shown to inhibit obesity-induced inflammation, as well as stimulate the release of catecholamine, a hormone that aids in decreasing fat cells [3]. (discovermagazine.com)
  • Five week old rats were fed a high-fat diet in order to induce obesity and supplemented with capsaicin (10mg per kg of body weight) or saline solution (control) for nine weeks. (nutraingredients.com)
  • "Comparative proteome analysis of a rat model of diet-induced obesity allowed us to outline possible pathways involved in the response to capsaicin," ​ wrote the researchers. (nutraingredients.com)
  • In the 40 years since the introduction of high-fructose corn syrup as a cost-effective sweetener in the American diet, rates of obesity in the U.S. have skyrocketed, according to the Centers for Disease Control and Prevention. (shakesville.com)
  • Consumption of prebiotic fibre early in life could offer some protection from obesity later in life, if they results of a rat study hold true for humans. (foodnavigator.com)
  • Previous research has indicated that early diet could play some role in susceptibility to obesity and type 2 diabetes later in life. (foodnavigator.com)
  • Consumption of a high-fat Western diet (HFWD) contributes to obesity, disrupted adipose endocrine function, and development of metabolic dysfunction (MetDys). (cdc.gov)
  • NIOSH reports that Appalachian coal miners have higher rates of obesity and metabolic dysfunction (MetDys) compared to the general U.S. adult population. (cdc.gov)
  • Consumption of a high-fat Western diet (HFWD) is associated with obesity and MetDys. (cdc.gov)
  • Although a person is at risk for During gestation, risk factors for obesity include maternal obesity throughout his life, we focus on specific develop- diet, overweight, and smoking. (cdc.gov)
  • In early childhood, feed- mental susceptibilities for obesity from gestation through ing practices, taste acquisition, and eating in the absence adolescence (Table). (cdc.gov)
  • glucocorticoids, protein restrictions, and maternal diet and obesity. (cdc.gov)
  • Effects of Long-Term Exposure to [Cr3O(O2CCH2CH3)6(H2O)3]+ in Wistar rats fed normal and high-fat diets. (emporia.edu)
  • The current study evaluates the effects of long-term supplementation on body mass and glucose metabolism in Wistar rats on traditional and cafeteria-style (high fat, high carbohydrate) diets. (emporia.edu)
  • Male Wistar rats were randomly assigned to one of four treatment groups: 1) control diet (milled Harlan Teklad LM-485 rodent diet), 2) control diet + 1 mg Cr3/kg body mass/day, 3) a cafeteria-style (CAF) diet (high fat, high carbohydrate), or 4) CAF diet + 1 mg Cr3/kg/day. (emporia.edu)
  • Methods: This study included 30 male wistar rats and was divided in four groups. (geneticsmr.org)
  • Forty male Wistar rats were randomly divided into four groups. (hindawi.com)
  • Wistar rats) [155], failed to influence food intake during a 1 h ad libitum feeding period, moderate to high doses of CBD (4.4 mg·kg −1 , i.p. [58]. (researchgate.net)
  • To investigate the effect of simvastatin on glucose homeostasis in streptozotocin induced type 2 diabetic rats. (hindawi.com)
  • Diabetic rats were induced by a single intraperitoneal injection of STZ. (hindawi.com)
  • the simvastatin intervention rats had a higher FPG compared to the diabetic rats and were more easily be induced to diabetes at the end of 4 weeks, FPG level of simvastatin treatment rats was increased compared with diabetic model rats after 12 weeks. (hindawi.com)
  • The target of the present study is to investigate the effect of simvastatin on FPG in STZ-induced diabetic rats. (hindawi.com)
  • in streptozotocin-induced diabetic rats. (nparks.gov.sg)
  • These data suggest that long-term Cr3 supplementation does not significantly affect body mass in rats consuming a normal diet or metabolic responses in rats consuming either diet. (emporia.edu)
  • Nonalcoholic fatty liver disease (NAFLD) is a globally observed metabolic disease with high prevalence both in adults and children. (mdpi.com)
  • Higher levels of dietary and serum omega-3 PUFAs, particularly long-chain omega PUFAs (DPA and DHA), might have beneficial effects on metabolic parameters and body composition among PCOS patients. (frontiersin.org)
  • Excessive insulin level is not only a potential cause of hyperandrogenemia but also one of the high-risk factors leading to metabolic syndromes among those with PCOS ( 6 ). (frontiersin.org)
  • reduces the impact of high-fat diet-induced metabolic endotoxaemia and inflammatory disorders. (bmj.com)
  • We previously reported that the gut microbiota is involved in high-fat diet-induced metabolic endotoxaemia, adipose tissue inflammation and metabolic disorders. (bmj.com)
  • 6 - 9 The link between high-fat diet-induced inflammation, oxidative stress, metabolic disorders, and gut microbiota, could be lipopolysaccharide (LPS)-dependent. (bmj.com)
  • Cooney reported that scientists at Princeton University had found that rats fed HFCS gained much more weight than those fed sucrose, packed on abdominal fat (which is considered particularly unhealthy) and had higher levels of fat in their blood. (dankennedy.net)
  • Hoebel's methodology has come under fire, as critics say he and his colleagues were hazy about some key details, including how many calories the HFCS-consuming rats were getting as compared to their sucrose-eating cousins. (dankennedy.net)
  • The rats stayed on these diets until they were 14 weeks of age, at which point they were transferred to a high fat/high sucrose diet for 6 weeks, with 45 per cent of energy coming from fat and 40 per cent from sucrose. (foodnavigator.com)
  • A glucose-stimulated BOLD fMRI study of hypothalamic dysfunction in mice fed a high-fat and high-sucrose diet Mohr, A. A., Alba M Garcia-Serrano, João Pp Vieira, Cecilia Skoug, Davidsson, H. & João MN Duarte, 2020 Aug 5, In : Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. (lu.se)
  • The objective of this work was to evaluate the effects of ethanol feeding with moderate or high fat diets upon hepatic and nonhepatic tissue contents of vitamin A. In the first experiment male rats were fed control or 30% ethanol liquid diets containing retinul acetate and either moderate fat (17% of total calories) or high fat (35% of total calories) for four weeks. (illinois.edu)
  • A krill oil supplemented diet suppresses hepatic steatosis in high-fat fed rats. (bvsalud.org)
  • The investigation of the molecular mechanisms of KO action in high-fat fed animals revealed a strong decrease in the activities of the mitochondrial citrate carrier and of the cytosolic acetyl-CoA carboxylase and fatty acid synthetase , which are both involved in hepatic de novo lipogenesis . (bvsalud.org)
  • The mRNA expression and enzymatic activity of cystathionine β -synthase and cystathionine γ -lyase were upregulated after quercetin, methionine, or quercetin plus methionine treatment and a more significant increase was observed for hepatic cystathionine β -synthase in the methionine plus quercetin treated rats, suggesting an interaction between methionine and quercetin. (hindawi.com)
  • The male rats on the high protein diet tended to have higher hepatic triglyceride content than the control-fed or high fibre rats. (foodnavigator.com)
  • Berry intake changes hepatic gene expression and DNA methylation patterns associated with high-fat diet. (lu.se)
  • Although we were not fully surprised by this finding, this is the first study, to our knowledge, to be reporting mental exhaustion in high-fat diet-induced obese rats. (news-medical.net)
  • We examined the effects of Lancemaside A and aglycon, its acid hydrolysis product from Lancemaside A, isolated from Codonopsis lanceolata water extract on triglyceride and free fatty acid in primary cultured adipocytes from obese rats fed high calorie high fat diet. (thieme-connect.com)
  • The lower energy intake in the TP and STP group was strongly related to the decrease in visceral fat weight. (rsc.org)
  • Recently the effects of high-fat diet (HFD) and/or sugar intake starting at juvenility were examined and showed that the impact of such obesogenic diets for 2-3 months, i.e. covering adolescence, is different from similar exposure but at adulthood. (nature.com)
  • We have selected HFD fed rat model for our study because it is a useful model of the putative effects of excess fat intake in humans and it represents the major sub type of diabetes mellitus, non insulin dependent diabetes mellitus (NIDDM). (biomedcentral.com)
  • By knocking down the expression of a protein in rat brains known to stimulate eating, researchers say they not only reduced the animals' calorie intake and weight, but also transformed their fat into a type that burns off more energy. (sciencedaily.com)
  • Various preclinical studies have investigated the effect of CBD on feeding behaviour in rodents [58, 93, 155,159,195], with results suggesting that higher doses may influence food intake several hours post-treatment. (researchgate.net)
  • Celery is also a good source of fiber, and results of a 2016 Cochrane review suggested that people with a high fiber intake may have lower blood pressure than those on a low fiber diet. (medicalnewstoday.com)
  • We are not adapted to the almost continuous intake of high-GI foodstuffs, and those with this metabolism suffer most. (kevinmd.com)
  • In particular, folic acid, a synthetic provitamin, may have adverse effects at high intake levels on normal transmembrane folate transport, inflammatory and proliferating cells in atherosclerotic lesions [ 12 ]. (hindawi.com)
  • A Princeton University research team has demonstrated that all sweeteners are not equal when it comes to weight gain: Rats with access to high-fructose corn syrup gained significantly more weight than those with access to table sugar, even when their overall caloric intake was the same. (shakesville.com)
  • This study aimed to investigate the effects on sperm production of inhaled metal nanoparticle s from stainless steel welding, and the potential exacerbation by intake of a high fat diet. (cdc.gov)
  • The high protein rats also had higher energy intake, higher plasma glucose and higher leptin. (foodnavigator.com)
  • Further study is needed to elucidate the mechanism(s) behind the effect of Cr3 on body mass in rats consuming a high-fat, high-carbohydrate diet. (emporia.edu)
  • Excess fat deposits in the white adipose tissue affects insulin mediated glucose metabolism in non adipose tissues, causes disordered insulin response and increases lipid deposition [ 2 ]. (biomedcentral.com)
  • There is evidence that manganese (Mn) metabolism is influenced by dietary fat. (usda.gov)
  • These studies were conducted to determine whether saturated fat, as compared to unsaturated fat, affected Mn absorption, retention and metabolism. (usda.gov)
  • The Johns Hopkins study, published in the journal Cell Metabolism , looks at two types of fat made by the body: white and brown adipose tissue. (sciencedaily.com)
  • If your daily calorie expenditure is 2,000 calories, but your diet and metabolism oblige you to lock away 500 calories daily as fat, you need consume 2,500 calories to survive. (kevinmd.com)
  • Many believe that high GI CHO is the problem, causing excessive fat storage, especially in those having the scavenger metabolism. (kevinmd.com)
  • This study was aimed at investigating the effects of quercetin on mRNA expression and activity of critical enzymes in homocysteine metabolism in rats fed a methionine-enriched diet. (hindawi.com)
  • Then, researchers split each of the groups into two, creating four sets of rats. (sciencedaily.com)
  • In the groin area of the NPY rats, researchers discovered not the expected white fat found in adult rats, but the telltale signs of brown fat in its place. (sciencedaily.com)
  • In 2015, researchers behind a study in mice concluded that apigenin and apigenin-rich diets reduced the expression of certain inflammatory proteins. (medicalnewstoday.com)
  • In a 2009 study , researchers gave rats apigenin and found that it stimulated nerve cell generation and improved the ability to learn and remember. (medicalnewstoday.com)
  • Results showed an 8 per cent decrease in body weight in capsaicin-fed animals, compared with controls, said the researchers. (nutraingredients.com)
  • Researchers found that rats given regular multivitamin and mineral supplements showed a significantly lower risk of developing colon cancer - even when exposed to carcinogens. (doctorshealthpress.com)
  • Researchers studied rats fed a high-fat diet (20% fat) over a 32-week period. (doctorshealthpress.com)
  • Despite this self-contained perfection, experimenters have tormented and killed hundreds of mice and rats in painful and pointless tests in order to promote marketing health claims for watermelons. (peta.org)
  • We show that-in both rats and mice-PB contains few GABAergic neurons, and that most of its GABAergic inputs arise from CeA. (iasp-pain.org)
  • In addition, induction of adiponectin, a hormone secreted by adipocytes, has been implicated in the protective action of saturated fat against the development of alcoholic fatty liver in mice. (medscape.com)
  • Hepatocyte death by apoptosis occurs in alcoholic fatty liver and has been demonstrated in rats and mice after ethanol feeding. (medscape.com)
  • Rats in the training groups were subjected to running on the treadmill at a speed of 20 meters per minute for 10 weeks (5 days per week) and their epididymal adipose tissue AQP7 content and insulin were assessed by Elisa. (ac.ir)
  • In addition, the rats fed HFD showed significant elevation in the basal plasma glucose, triglyceride, total cholesterol and insulin levels at the end of four weeks of dietary manipulation as compared to NPD fed control groups (Table 2 ). (biomedcentral.com)
  • This study also shows that low levels of hypothalamic NPY increase spontaneous physical activity, improve blood sugar levels and enhance insulin sensitivity in rats, but it remains undetermined whether this brown fat transformation also contributes to these effects. (sciencedaily.com)
  • The body weights and epididymal fat weights were significantly reduced and the serum lipid profiles were improved in the group fed the diet containing BAB compared to the HD group. (nih.gov)
  • Furthermore, mRNA expression levels of ObRb, a gene related to leptin sensitivity in the hypothalamus, were significantly higher in the BAB groups than in the HD group. (nih.gov)
  • Rats consuming the CAF + Cr3 diet tended to have a significantly higher body mass than rats consuming the CAF diet, but necropsy results showed no difference in visceral fat or body wall thickness between groups. (emporia.edu)
  • A review of 16 studies in 810 people with high blood pressure or an elevated risk of it found that taking 100-2,000 mg of GSE daily significantly reduced systolic and diastolic blood pressure (the top and bottom number) by an average of 6.08 mmHg and 2.8 mmHg, respectively. (healthline.com)
  • Rats were fed for 108 days with a high-fat diet, and at the end of the experiment, they were overweight and had significantly increased serum levels of glucose (2.0-fold), total cholesterol (1.6-fold), and low-density lipoprotein (LDL)-cholesterol (7.7- fold). (uhu.es)
  • We have previously shown that long-term exposure (8-12 weeks) to high-fat diet (HFD) during adolescence (from weaning to adulthood), but not at adulthood, was associated with altered amygdala and hippocampal functions. (nature.com)
  • Here, we examined in male rats whether acute exposure (7-9 days) to HFD during juvenility [from postnatal day (PND) 21 to PND 28-30] or adulthood (from PND 60 to PND 67-69) is sufficient to affect hippocampal functions and whether it is also dependent on GRs activation. (nature.com)
  • An association between dyslipidemia, LDL oxidation, CD36 expression, ROS generation, thioredoxin-interacting protein (TXNIP) upregulation, and NLRP3 inflammasome activation was demonstrated by DSS exposure in HFD-fed rats. (edu.sa)
  • Conclusion: Exposure to GMA-SS welding fumes lowered sperm production in two strains of rats, whereas high fat diet lowered serum testosterone. (cdc.gov)
  • Macondo well surrogate oil) on ventilatory and non-ventilatory functions of the lung in a rat model 1 and 28 d after acute exposure, and 1, 28 and 90 d following sub-chronic exposure. (cdc.gov)
  • In this study, we investigated the effects of, and determine interactions between, HFWD-consumption and silica-exposure on airway epithelial ion transport and smooth muscle reactivity in the F344 rat. (cdc.gov)
  • Babies have ample stores of brown fat at birth as a defense against the cold, but it mostly disappears, as adults have very little of this calorie-burning tissue. (sciencedaily.com)
  • calorie-dense, highly processed, and adulterated products containing unnatural combinations of salt, fat, sugar, and high glycemic index (GI) carbohydrates that overwhelm natural satiety mechanisms. (kevinmd.com)
  • I believe that the best alternative is the low-calorie, high-fat (LCHF) diet, first popularized in 1863 by William Banting, whose short account of his experience, "A Letter on Corpulence, Addressed to the Public," started the first mass dieting craze. (kevinmd.com)
  • Intermittent versus daily calorie restriction: Which diet regimen is more effective for weight loss? (researchgate.net)
  • Some evidence suggests that intermittent calorie restriction may be superior to daily calorie restriction for the retention of lean mass at the expense of fat mass (9) . (researchgate.net)
  • Grummer, MA & Erdman, JW 1986, ' Effect of chronic ethanol consumption and moderate or high fat diet upon tissue distribution of vitamin A in rats fed either vitamin A or β-carotene ', Nutrition Research , vol. 6, no. 1, pp. 61-73. (illinois.edu)
  • The aim of this study was to evaluate the effect of aerobic exercise training on epididymal adipose tissue AQP7 content in rats fed a high fat diet. (ac.ir)
  • Bi says he believes that the transformation from white to brown fat resulting from NPY suppression may be due to activation of brown fat stem cells contained in white fat tissue. (sciencedaily.com)
  • Due to its high antioxidant content, GSE can help prevent disease and protect against oxidative stress, tissue damage, and inflammation. (healthline.com)
  • Furthermore, protein expression in fat tissue showed the up-regulation of 10 proteins and the down-regulation of another 10 proteins following supplementation with capsaicin. (nutraingredients.com)
  • 2016). Characterization of TGF-β expression and signaling profile in the adipose tissue of rats fed with high-fat and energy-restricted diets . (up.pt)
  • concentrations in rat blood, urine, and fetal tissue. (cdc.gov)
  • It is concluded that quercetin reduces serum homocysteine by increasing remethylation and transsulfuration of homocysteine in rats exposed to a methionine-enriched diet. (hindawi.com)
  • Overall, HF diet rats had lower serum testosterone levels compared to rats on regular diet. (cdc.gov)
  • Twenty-eight male Wister rats (4-6 weeks) were randomly divided into two groups: Normal diet (14) and high fat diet (14). (ac.ir)
  • In male rats fed the high the high fibre diet, weight gain was attenuated through to the end of the study. (foodnavigator.com)
  • Accordingly, this review examines the effects of daily CR versus intermittent CR on weight loss, fat mass loss and lean mass retention in overweight and obese adults. (researchgate.net)
  • These findings suggest that these diets are equally as effective in decreasing body weight and fat mass, although intermittent CR may be more effective for the retention of lean mass. (researchgate.net)
  • The high fibre rats had higher lean mass and lower fat mass than the high protein rats, and higher plasma amylin compared to the control rats. (foodnavigator.com)
  • When rats are drinking high-fructose corn syrup at levels well below those in soda pop, they're becoming obese - every single one, across the board. (dankennedy.net)
  • High fructose corn syrup is difficult to avoid in today's diet. (dankennedy.net)
  • The only biochemical change noted was animals fed low manganese and saturated fats, as compared to other diets, had reduced activity of a manganese-containing enzyme in the heart. (usda.gov)
  • In study 1, the TP and STP diet increased the caecal short-chain fatty acid (SCFA) content compared to that of a control diet. (rsc.org)
  • The rats were fed for 8 weeks with a control diet containing 10 kcal% from fat (CD), a high-fat diet containing 60 kcal% from fat (HD), or a high-fat diet with 1% or 2% freeze-dried ethanolic extract powder of BAB (BAB-1 and BAB-2). (nih.gov)
  • One group fed standard diet [control (C)], second group fed standard diet with vitamin D, third group fed hypercaloric diets [obese (Ob], and fourth group fed hypercaloric diets with vitamin D, for 22 weeks. (geneticsmr.org)
  • After 10 weeks of feeding with normal or high-fat food, each of the groups were divided into two groups: control (7) and training (7). (ac.ir)
  • One of the groups was fed with normal pellet diet and they served as the control group, whereas the other group was on a high fat diet for 4 weeks. (biomedcentral.com)
  • Normal control rats were fed with standard diet, others were fed with high-fat diet. (hindawi.com)
  • Both rat groups gained weight during the trial, but the high-fat diet group, not surprisingly, gained more than the control group. (news-medical.net)
  • The high-fat diet group performed poorly on the novel recognition test when compared with the control group. (news-medical.net)
  • For five weeks, two groups of rats were fed a regular diet, with one group also treated with a virus to inhibit NPY expression and the other left as a control group. (sciencedaily.com)
  • One of the treated groups of rats and one of the control groups were fed a regular diet while the other treated and control groups got a high-fat diet. (sciencedaily.com)
  • Of the rats on the regular diet, the control group weighed more at the end of 11 weeks than those rats in which hypothalamic NPY expression was knocked down. (sciencedaily.com)
  • Background and Aims: Weight-loss diets reduce body weight and improve blood pressure control in hypertensive patients. (researchgate.net)
  • Rats were fed for 6 weeks the following diets, that is, control, 0.5% quercetin, 1.0% methionine, and 1.0% methionine plus 0.5% quercetin diets. (hindawi.com)
  • The study involved litters culled to 10 pups, of which the mother was given ad libitum access to a control diet throughout gestation. (foodnavigator.com)
  • At 21 days the pups were weaned and six litters were placed on three experimental diets: a control diet, a high prebiotic fibre diet, and a high protein diet. (foodnavigator.com)
  • This study examined whether the form of dietary fat affects manganese absorption and utilization. (usda.gov)
  • Spent turmeric contains high levels of dietary fibre and resistant starch (RS), which have fermentation potential in vitro . (rsc.org)
  • We further demonstrated that these chronic oxytocin effects result from 1) maintenance of energy expenditure at preintervention levels despite ongoing weight loss, 2) a reduction in respiratory quotient, consistent with increased fat oxidation, and 3) an enhanced satiety response to cholecystokinin-8 and associated decrease of meal size. (nih.gov)
  • The vitamin A levels in lungs and adrenals were higher in ethanol-fed rats, whereas the vitamin A levels of kidneys of ethanol-fed groups were either no different or lower than in controls. (illinois.edu)
  • Feeding normal rats with high dietary levels of saturated fat leads to pathological conditions, which are quite similar to syndrome X in humans. (biomedcentral.com)
  • Toward this goal, we observed the different effect between simvastatin intervention rats and simvastatin treatment rats, especially on FPG levels of various periods. (hindawi.com)
  • The research team measured the rats' weight, blood glucose and ketone levels twice a week. (news-medical.net)
  • Blood glucose levels fluctuated more in the high-fat diet group as well. (news-medical.net)
  • They confirmed this change by looking at levels of mitochondrial uncoupling protein-1, or UCP-1, through which brown fat burns to produce heat. (sciencedaily.com)
  • Higher antioxidant levels in black garlic may also help to prevent complications related to diabetes. (webmd.com)
  • They contain high levels of magnesium, zinc, and protein, so they're actually quite good for you. (peta.org)
  • However, some studies show higher levels of activation of Hedgehog pathways in patients with the most advanced fatty liver disease. (medscape.com)
  • Also, the effects of ethanol consumption are more pronounced in combination with a high fat diet. (illinois.edu)
  • The slimming ingredients market can be divided into five groups based on the mechanisms of action - boosting fat burning/ thermogenesis, inhibiting protein breakdown, suppressing appetite/ boosting satiety (feeling of fullness), blocking fat absorption, and regulating mood (linked to food consumption). (nutraingredients.com)
  • These data suggest that while a long term diet high in protein predisposed to an obese phenotype when rats are given a high energy diet in adulthood, consumption of a high fibre diet during growth may provide some protection. (foodnavigator.com)
  • In experiment I, adult rats were fed diets containing either 0.7 or 100.4 ug/g Mn with the fat source as high-linoleic safflower oil or stearic acid. (usda.gov)
  • The second experiment was similar to the first except that diets contained β-carotene and all rats received a dose of [ 3 H] β-carotene. (illinois.edu)
  • The simvastatin intervention rats were fed with simvastatin during the experiment process, and the simvastatin treatment rats were fed with simvastatin after diabetes rats were induced. (hindawi.com)
  • Bi and his colleagues designed an experiment to see if suppressing the appetite-stimulating neuropeptide Y (NPY) protein in the dorsomedial hypothalamus of the brain would decrease body fat in rats. (sciencedaily.com)
  • The high-fat diet was purchased from standard diet (SD) consists of 6% fat, 64% carbohydrate and 23% protein, and high-fat diet (HFD) consists of 25% fat, 48% carbohydrate, and 20% protein. (hindawi.com)
  • They used this protein as a marker to determine that the fat that should have been white was instead brown. (sciencedaily.com)
  • Capsaicin, the compound gives red chilli pepper its heat, may exert its benefits at the protein level to boost fat burning and energy production, says new research. (nutraingredients.com)
  • In the females, there were early reductions in body weight that moderated until the final two weeks, during which they weighed less than the females on the high protein diet. (foodnavigator.com)
  • In both males and females, final body weight was higher in the high protein group than in the high fibre group. (foodnavigator.com)
  • Feeding low-protein diets to pregnant rats produces a increased more than in children not exposed to tobacco in broad spectrum of disorders in their offspring (7): hyper- utero. (cdc.gov)
  • The initial velocity decreased at enzyme concentrations higher than 0.13 mg protein per 2.0 ml of incubation mixture. (who.int)
  • In the first study, rats were administered 10% turmeric powder (TP) or spent turmeric powder (STP) in a high-fat (HF) diet for 28 d. (rsc.org)
  • In the second study, rats were fed 10% STP in a HF diet with or without antibiotics for 15 d. (rsc.org)
  • In the third study, rats were treated with a STP-containing suspension. (rsc.org)
  • In study 2, after caecal fermentation suppression with antibiotics, STP treatment decreased the visceral fat mass. (rsc.org)
  • The purpose of this study was to evaluate High fat diet fed rats for the development of hypertriglyceridemia, hypercholesterolemia, hyperinsulinemia and hyperglycemia and to assess their vascular responses to 5-Hydroxytryptamine and Angiotensin II. (biomedcentral.com)
  • The aim of this study was to elucidate the contractile responses to 5-HT and Ang II in HFD fed rat thoracic aorta which will provide an avenue for further exploratory studies. (biomedcentral.com)
  • This study demonstrates that the type of fat in a meal influences manganese absorption. (usda.gov)
  • One message from this study is to avoid [a] high-fat diet, which not only makes one become obese, but also has consequences on cognitive capability,' the authors wrote. (news-medical.net)
  • One study looked at the effect of celery seed extracts on blood pressure in rats that either had normal blood pressure and or artificially induced hypertension . (medicalnewstoday.com)
  • Another study in 29 adults with high blood pressure found that taking 300 mg of GSE daily lowered systolic blood pressure by 5.6% and diastolic blood pressure by 4.7% after 6 weeks. (healthline.com)
  • In the present study, it also appeared as though a lower proportion of total fat-free mass was lost in response to IER when compared with CER. (researchgate.net)
  • While the study is on rats, this is where most major health breakthroughs germinate. (doctorshealthpress.com)
  • The colon cancer induced in the study rats had characteristics that mimic human colon cancer. (doctorshealthpress.com)
  • animals remained on their assigned diet for the study duration. (cdc.gov)
  • Recently, the role of inflammation in the central nervous system, particularly the hypothalamus in diet-induced IR progress, has been noted in rodent models and human (Posey et al. (deepdyve.com)
  • Could the use of vitamin and mineral supplements in a regular diet help reduce the risk of colon cancer and protect against carcinogens? (doctorshealthpress.com)
  • Intraperitoneal glucose tolerance test was performed after 4 weeks of feeding. (biomedcentral.com)
  • One group was fed a high-fat diet, and the other ate a standard diet for six weeks. (news-medical.net)
  • Results reveal similar weight loss and fat mass loss with 3 to 12 weeks' intermittent CR (4-8%, 11-16%, respectively) and daily CR (5-8%, 10-20%, respectively). (researchgate.net)
  • Rats were fed regular or high fat (HF) diet for 24 weeks and were exposed to 20 mg/m3 of gas metal arc-stainless steel (GMA-SS) welding fumes or filtered air for 3 h/day, 4 days/week for 5 weeks, during weeks 7-12. (cdc.gov)
  • Conclusion: The cardiac Extrinsic pathways of apoptosis were activated in rats fed with high fat diet. (geneticsmr.org)
  • While brown fat seems to vanish in humans as they emerge from infancy, the brown fat stem cells may never disappear and may just become inactive as people age. (sciencedaily.com)
  • EGEEA and EGEE for pregnant rats and humans. (cdc.gov)
  • In both experiments the amount of vitamin A stored in the liver was lower in ethanol-fed rats, and the amount of liver vitamin A was lower in ethanol-fed rats on the high fat diet compared to those on low fat diet. (illinois.edu)
  • The statistically significant increases in liver malondialdehyde in HFDF rats were reduced after treatment with P farcta. (uwi.edu)
  • Fatty liver is the accumulation of triglycerides and other fats in the liver cells. (medscape.com)
  • These data indicate that simvastatin intervention rats may cause hyperglycemia by impairing the function of islet β cells and have an adverse effect on glucose homeostasis, especially on FPG level. (hindawi.com)
  • However, very little information is available in the literature regarding the vascular contractile responses to vasopressor agents such as 5-HT and Ang II in HFD fed rats. (biomedcentral.com)
  • Animals with pain after chronic constriction injury of the infraorbital nerve (CCI-Pain) displayed higher spontaneous and evoked activity in PB neurons, and a dramatic increase in after-discharges-responses that far outlast the stimulus-compared to controls. (iasp-pain.org)
  • There isn't enough reliable information to know if chia is safe to use when pregnant or breast-feeding. (webmd.com)
  • Individuals with excess fat accumulation that can impair health are called overweight or obese. (frontiersin.org)
  • Rats fed a high-fat and low-fiber diet and exposed to carcinogens developed pre-cancerous lesions. (doctorshealthpress.com)
  • But rats undergoing similar treatment, but given daily multivitamin supplements, showed a significant (84%) reduction in the formation of pre-cancerous lesions. (doctorshealthpress.com)
  • Rats were housed in wire-floored cages under a 12 h light-dark cycle for at least 7 days prior to treatment and were fed with standard laboratory chow and tap water ad libitum. (hindawi.com)
  • Ayerza, R., Jr. and Coates, W. Effect of dietary alpha-linolenic fatty acid derived from chia when fed as ground seed, whole seed and oil on lipid content and fatty acid composition of rat plasma. (webmd.com)
  • Our results indicated that the dietary long-chain omega-3 polyunsaturated fatty acids (PUFA) intakes were negatively associated with HOMA-IR (β = -0.089, P = 0.040), fat mass (β = -0.022, P = 0.047), and body fat percentage (β = -0.026, P = 0.032). (frontiersin.org)
  • There is considerable evidence for a pro- fatty acids in the diet as food additives or tective effect of dietary omega-3 fatty acids as therapeutic substances, it is important in the prevention of heart disease [ 12-15 ], to determine the extent of any effects, and especially in a high-risk population [ 16,17 ]. (who.int)
  • Heart tissues were collected for Quantitative Real-time polymerase chain reaction (qRT-PCR) to detect different genetic markers of apoptosis (FAS, FAS-L). Results: A significant increase in FAS, FAS-L gene expression in rats fed with high fat diet was found. (geneticsmr.org)
  • What was a surprise, however, was what they found after they checked the fat content of rats after death. (sciencedaily.com)
  • GSE supplements have been found to reduce LDL oxidation triggered by high fat diets in several animal studies . (healthline.com)
  • The British Journal of Sports Medicine paper "Evidence that supports the prescription of low-carbohydrate high-fat diets: a narrative review" outlines his position, and his recommendations can be found in the book, The Banting Pocket Guide . (kevinmd.com)
  • It was found that when parasitaemia was high antibody titre was low and as parasitaemia declined antibody titre rose sharply. (who.int)
  • The present work aimed to investigate the possible protective effect of vitamin D on cardiac apoptosis in rats fed with a high fat diet. (geneticsmr.org)
  • A rapid method for the separation of vitamin D and its metabolites by ultra-high performance supercritical fluid chromatography-mass spectrometry. (lu.se)
  • however aerobic exercise training increased AQP7 in both normal and high fat diet groups(P= 0.003). (ac.ir)
  • The rats were divided into six groups, which were exposed to different combinations of supplements and carcinogens. (doctorshealthpress.com)
  • Reducing high blood sugar helps prevent serious health issues, such as diabetes symptoms, kidney dysfunction, and more. (webmd.com)
  • The KO supplemented animals also retained an efficient mitochondrial oxidative phosphorylation , most probably as a consequence of a KO-induced arrest of the uncoupling effects of a high-fat diet . (bvsalud.org)
  • Manganese absorption by animals fed saturated fats was less than 10% that of animals fed unsaturated fats. (usda.gov)
  • Although absorption was lower, animals fed saturated fats retained the absorbed manganese longer than animals fed unsaturated fats. (usda.gov)
  • After two days, the animals were fed a test meal of 54**Mn followed by whole-body counting for ten days. (usda.gov)
  • Biomass of the acidophilic green alga Coccomyxa onubensis may be used as a food source for animals without collateral toxic effects, as diet supplemented the microalga has significant hypoglycemic and hypocholesterolemic effects on healthy animals. (uhu.es)
  • At the end of the final feeding stage, final body weight was measured and body composition was determined under anaesthetic using an x-ray technique for small animals. (foodnavigator.com)