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  • mucinous
  • Microscopic description revealed a lepidic (mucinous) adenocarcinoma in all five cases. (edoriumjournals.com)
  • Type-I cystic adenomatoid malformation (CAM) has recently been identified as a precursor lesion for the development of mucinous BAC, but these cases are rare. (wikipedia.org)
  • Microscopic characteristics of rhabdoid cells include: Oval to polygonal cell shape Eosinophilic, hyaline-like perinuclear agglomerations of intermediate filaments Compressed, eccentric nuclei Prominent central macronucleoli (one or two) Abundant eosinophilic cytoplasm Reticular chromatin pattern The differential diagnosis of LCLC-RP includes secondary metastatic lesions, melignant melanoma of the lung with rhabdoid phenotype, mucinous adenocarcinomas (particularly those featuring signet-ring cells), rhabdomyosarcoma, epitheloid angiosarcoma, pleural mesothelioma, and plasmacytoma. (wikipedia.org)
  • smokers
  • Inhibitor of EML4-ALK crizotinib shows benefit in a subset of non-small cell lung cancer that is characterized by the EML4-ALK fusion oncogene, found in some relatively young, never or light smokers with adenocarcinoma. (wikipedia.org)
  • metastatic
  • Sarcomas metastatic to the lung outnumber primary pulmonary sarcomas and, depending on one's index of suspicion, the pathologist may need to take a more active role in prompting clinical colleagues to consider an occult or remote soft tissue primary. (redorbit.com)
  • EGFR
  • Mutations of the EGFR gene are relatively rare (0/23). (wikipedia.org)
  • 4,5 SCLC transformation is a relatively rare acquired drug resistance mechanism in EGFR-mutant LADC that has been treated with TKI therapy. (targetedonc.com)
  • exceptionally
  • FA is exceptionally rare in children, with only a handful of cases reported to date, However, several case reports have involved FA's in pregnant women or the early postnatal period. (wikipedia.org)
  • malignant
  • The whorled eosinophilic inclusions in LCLC-RP cells give it a microscopic resemblance to malignant cells found in rhabdomyosarcoma (RMS), a rare neoplasm arising from transformed skeletal muscle. (wikipedia.org)
  • BAC is considered a pre-invasive malignant lesion that, after further mutation and progression, eventually generates an invasive adenocarcinoma. (wikipedia.org)
  • detection
  • Accordingly, detection of elevated pulmonary artery pressure should not immediately result in treatment, but instead lead to an additional and careful diagnostic workup, including confirmation of the presence of pulmonary hypertension. (oncologynurseadvisor.com)
  • A CT scan of the chest (Fig. 1 ) was indicated following detection of a pulmonary nodule in the right upper field on routine chest -x-ray. (biomedcentral.com)
  • particularly
  • In a study of 408 consecutive patients with SCLC, Quoix and colleagues found that presentation as a solitary pulmonary nodule (SPN) is particularly indicative of a c-SCLC - about 2/3 of their SPN's were pathologically confirmed to be c-SCLC's containing a large cell carcinoma component. (wikipedia.org)
  • cells
  • al have proven that curcumin causes apoptosis or cell death in lung adenocarcinoma cells and this was accompanied by changes in oxidative stress levels (balance between prooxidant and antioxidant agents). (turmericforhealth.com)
  • Another study also proves that curcuminoid prevents the proliferation of lung adenocarcinoma cells by inducing formation of reactive oxygen species and damaging cancer cells. (turmericforhealth.com)
  • Despite
  • Despite advances in echocardiography, pulmonary hypertension still requires a right heart catheterization (RHC) demonstrating mean pulmonary arterial pressure ≥ 25 mm Hg at rest for confirmation. (oncologynurseadvisor.com)
  • Despite the stability of persistent lesions in the liver and lymph nodes, this medication was discontinued, due to the appearance of a discrete pulmonary infiltrate, which suggested gemcitabine toxicity. (biomedcentral.com)
  • include
  • Typically, markers expressed in LCLC-RP include those seen in "generic" NSCLC's, such as epithelial membrane antigen (EMA, 61%), various cytokeratins (CK's, 80%), and markers associated with the underlying "parent" pulmonary carcinoma. (wikipedia.org)
  • central
  • A second critical information from the RHC that is central to the diagnosis is the pulmonary arterial occlusion or wedge pressure (Pawp). (oncologynurseadvisor.com)
  • In a review of literature compiled by Kallenburg and co-workers, less than 30% of GCCLs arose in the hilum or other parts of the "central" pulmonary tree. (wikipedia.org)