• Immune checkpoint inhibitors in lung tumors with rare histologies and other thoracic malignancies. (figshare.com)
  • Testicular germ cell tumors (TGCT), evenly divided into two histologic types, seminomas and nonseminomas, are the most common malignancy among males between ages 15 to 44 years [1, 2]. (utrgv.edu)
  • Malignant tumors of the salivary glands are rare, comprising from 1 to 6% of all head and neck tumors and the parotid is most commonly affected, accounting for 70% of the lesions 1 . (bvsalud.org)
  • V. G. McDermott, S. Mackenzie and G. M. Hendry, "Case Report: Primary Intrathoracic Rhabdomyosarcoma: A Rare Childhood Malignancy," British Journal of Radiology, Vol. 66, No. 790, 1993, pp. 937-941. (scirp.org)
  • Rare Childhood Malignancy. (bvsalud.org)
  • The differential diagnosis when encountering a high-grade B-cell malignancy at a cutaneous site is broad and includes primary cutaneous follicle center lymphoma (PCFCL), primary cutaneous diffuse large B-cell lymphoma, leg type (PCDLBCL-LT), high-grade B-cell lymphoma with MYC and BCL2 rearrangements (HGBCL- MYC/BCL2 ), and other potential entities which must all be carefully considered before rendering a final diagnosis. (hindawi.com)
  • Gynecological cancers are characterized by rare entities more frequently than any other system. (ejgo.net)
  • For example, all epithelial and non-epithelial neoplasms of the ovary are designated as rare cancers, with the exception of High Grade Serous carcinomas. (ejgo.net)
  • Under this perspective, the scope of this special issue is to comprehensively present novel data regarding rare gynecological cancers and to disseminate experts' opinions that could assist in the appropriate managemen of these patients. (ejgo.net)
  • In this guide, this group of cancers is referred to as "ovarian/fallopian tube cancer" because peritoneal cancer is relatively rare. (cancer.net)
  • Over the last 17 years, stereotactic body radiation therapy (SBRT) has shown a high degree of safety and local control for stage I lung cancers and other localized malignancies. (frontiersin.org)
  • Epithelial ovarian cancers (EOC) are the second-most common gynecologic malignancy. (thieme-connect.de)
  • Primary urethral cancer is an extremely rare and aggressive malignancy. (bjmo.be)
  • The standardized incidence ratios (SIRs) of the overall and site-specific malignancies were estimated and compared with the incidence of cancer in the general population retrieved from the National Cancer Registry. (nature.com)
  • We present the case of a 62-year-old male with squamous cell carcinoma of the posterior urethra treated at our institution followed by an in-depth discussion on presentation, diagnosis and treatment of this rare cancer. (bjmo.be)
  • However, there exists controversies about whether PNI has prognostic significance toward cancer malignancy. (wikipedia.org)
  • This is only one of many examples demonstrating the power of technology and its ability to bring together rare cancer populations in a meaningful and impactful way. (flatiron.com)
  • Technology can also be helpful in connecting rare cancer populations to generate real-world evidence for research questions that are not easily answered in clinical trials, and even improve recruitment of patients onto prospective clinical studies. (flatiron.com)
  • We want to improve treatment efficacy for patients with this rare, incurable blood cancer. (janssen.com)
  • These can be caused by bacterial or viral infections, cancer ( malignancy ), or other rare causes. (medlineplus.gov)
  • One hundred years ago, lung cancer was a rare malignancy ( 1 ). (frontiersin.org)
  • Conclusion MOC is a challenging and rare subtype of ovarian cancer requiring special attention and recognition. (thieme-connect.de)
  • 1 ] Mucinous ovarian cancer (MOC) is a rare subtype of malignant ovarian cancer. (thieme-connect.de)
  • However, intussusception due to a jejunal metastasis of combined lung cancer is extremely rare [ 3 ]. (hindawi.com)
  • Fallopian tube cancer is the least common of gynaecological malignancies. (annals.edu.sg)
  • Ovarian cancer is the most common gynaecological malignancy with over 5000 new cases diagnosed every year in the UK and 22 000 in the. (annals.edu.sg)
  • Iris melanoma is the rarest cancer in this family, making up only 2% to 3% of cases. (eyecancer.com)
  • Reports of cancer from expo- sure to malignant cells are quite rare. (cdc.gov)
  • Diffuse large B-cell lymphoma, not otherwise specified (DLBCL NOS) is the most common lymphoid malignancy in the Western world and classically presents as a rapidly enlarging nodal or extranodal mass. (hindawi.com)
  • Primary pleural rhabdomyosarcoma is an extremely rare intrathoracic malignancy. (scirp.org)
  • Malignant pleural mesothelioma (MPM) is a rare malignancy with few treatment options. (medpagetoday.com)
  • Pathological mandibular fractures are rare and account for up to 2% of mandibular fractures. (bmj.com)
  • Although pathological fractures through a primary bone malignancy are rare, these should be recognised quickly in order to achieve better outcomes. (lu.se)
  • Primary tumours associated with nerve cells are exceptionally rare whereupon the majority of these tumours present as benign. (hilarispublisher.com)
  • Rarely, malignancies may arise intrinsic to otherwise incidental benign nodal inclusions. (hindawi.com)
  • Pathologists should carefully evaluate lymph node inclusions to ensure that intrinsic malignancies are not missed within rare otherwise benign appearing incidental epithelial rests. (hindawi.com)
  • Analogously, rare carcinomas are encountered among uterine and cervical carcinomas. (ejgo.net)
  • They were observed until the diagnosis of malignancy, death, or end of the observational period, December 2020. (nature.com)
  • In 2020, haematological malignancies were attributed to approximately 294,000 diagnoses and approximately 148,000 deaths in Europe. (janssen.com)
  • Carcinoma of the vulva is an uncommon malignancy, but one that is amenable to early diagnosis if symptoms and signs are appropriately investigated. (annals.edu.sg)
  • Neurolymphomatosis (NL) is a rare disease characterized by malignant lymphocytes infiltrating various structures of the nervous system. (researchgate.net)
  • Clinical case description of a papillary mucinous cystadenocarcinoma, extremely rare malignant tumor in the salivary gland and difficult to diagnose, in geriatric patient. (bvsalud.org)
  • We are committed to advancing the science and treatment of hematologic malignancies and look forward to presenting the latest research from our robust portfolio and pipeline during ASH 2021," said Peter Lebowitz, M.D., Ph.D., Global Therapeutic Area Head, Oncology, Janssen Research & Development, LLC. (jnj.com)
  • Why primary tumours/malignancies of the nerve cells are so rare? (hilarispublisher.com)
  • myeloma involves the mandible more commonly than metastatic disease (breast, lung, prostate), whereas primary malignancy (osteosarcoma) is rare. (bmj.com)
  • Moreover, primary signet ring cell carcinomaof the appendix is an exceedingly rare entity. (wjgnet.com)
  • In the present report, we describe a rare case of primary signet ring cell carcinoma of the appendix with ovarian metastasesand unresectable peritoneal dissemination occurring in a 45-year-old female patient. (wjgnet.com)
  • Uveal melanoma is the most common primary intraocular malignancy in adults. (eyecancer.com)
  • Vulvar dermatofibrosarcoma is a rare fibrous tumor of intermediate grade malignancy, with a tendency for local recurrence, and rarely metastasizes. (imrpress.com)
  • It is very rare disease in USA and Europe, seen rarely in tropical and subtropical countries in persons with poor personal hygiene. (atmph.org)
  • Papillary cystadenocarcinoma, in turn, comprises an extremely rare lesion, accounting for 0.5% of all epithelial lesions affecting the salivary glands 2 and according to the second largest survey on cystadenocarcinomas described in the literature, the highest prevalence is also observed in the major salivary glands 3 . (bvsalud.org)
  • The presence of lymph node inclusions can pose a challenge in assessment of benignity and malignancy, on frozen and permanent histologic sections. (hindawi.com)
  • Lymph node inclusions of different types, including nevoid, squamous, and glandular, are rare but have been reported in multiple different anatomic locations including the axilla. (hindawi.com)
  • Paraganglioma is a rare type of neuroendocrine tumor with the ability of neuropeptide and catecholamine secretion. (springermedizin.at)
  • Background : Phaeochromocytoma is a rare neuroendocrine tumour with highly variable clinical presentation including serious and potentially lethal cardiovascular complications. (bvsalud.org)
  • Finding other patients that share similar journeys, connecting with physicians who have the expertise in managing these diseases, locating all available clinical trial options, answering important research questions using real-world data, even designing prospective clinical trials to recruit enough patients with hematologic malignancies have barriers -- because it is hard to navigate and find all the right needles within a national haystack. (flatiron.com)
  • At this year's ASH Annual Meeting, Flatiron Health's research contributions reflect ways in which we've used technology to open opportunities and answer difficult research questions for patients with rare diseases. (flatiron.com)
  • National Organization for Rare Diseases: "Multiple Myeloma. (webmd.com)
  • rare hereditary diseases, hazardous environmental conditions, unusual toxic exposures, or unsafe consumer products may only be suspected or identified after a complete, detailed and through autopsy rules out more likely causes. (medscape.com)
  • In this post, we explore how new research on rare genetic diseases is contributing to our understanding of COVID-19 occurrence and outcomes and discuss potential clinical and public health implications. (cdc.gov)
  • Rare Disease PHGKB is an online, continuously updated, searchable database of published scientific literature, CDC and NIH resources, and other information that address the public health impact and translation of genomic and other precision health discoveries into improved health outcomes related to rare diseases. (cdc.gov)
  • We can strengthen connections for patients with hematologic malignancies and open opportunities for research and patient care. (flatiron.com)
  • It is important to recognize the condition as it is often misdiagnosed for a malignancy, putting the younger patient at risk of over-treatment with the resultant loss of hormo-nal function and fertility. (who.int)
  • Patient with 86 years old was referred for treatment with nodular lesion on the inner side of left lower lip extending to the bucal mucosa, without any clinical appearances of malignancy. (bvsalud.org)
  • The location of this infestation at genital region is, however, an extremely rare occurrence. (atmph.org)
  • The report shows an extremely rare case of an extra-adrenal abdominal paraganglioma, successfully managed with a laparoscopic approach. (springermedizin.at)
  • The finding of a neoplasm in a hernia sac is extremely rare and is reported to occur in less than 0.5% of examined hernia sacs. (ispub.com)
  • Pancreatic TB is an extremely rare was referred for endo-ultrasonography and clinical entity [ 5 ]. (who.int)
  • The Europeans have looked into this and have issued several guidance documents both broadly, you know, the European Medicines Agency and also, individual countries have issued documents stating their findings about a possible link between this rare condition and vaccination with AstraZeneca's COVID-19 vaccine. (cdc.gov)
  • Mutations are rare in nerve cells due to their inability to proliferate and regenerate. (hilarispublisher.com)
  • In rare cases, a definitive cause of death may not be identified following a complete and thorough autopsy. (medscape.com)
  • We've leveraged technology to learn from patients with hematologic malignancies in order to break these barriers rare populations have to advance research and improve access to clinical trials. (flatiron.com)
  • stated that massive oedema of the ovary is a rare entity affecting mainly young women [2]. (who.int)
  • The authors present here one case of genital myiasis affecting a village woman with genital prolapse and advanced vaginal malignancy. (atmph.org)
  • We present a rare case of a large hepatic cyst causing syncope. (bvsalud.org)
  • This study aimed to evaluate the relative risk of malignancy in patients with Takayasu's arteritis compared to that in the general population. (nature.com)
  • An increased risk of malignancy was observed in patients with Takayasu's arteritis compared to that in the general population in this large-scale nationwide population study of Korean health insurance data. (nature.com)
  • However, information regarding the risk of malignancies in patients with large-vessel vasculitis remains scarce. (nature.com)
  • therefore, cohort studies have limited ability to reveal the risk of malignancies. (nature.com)
  • Here, we evaluated the relative risk of malignancies in patients with TAK and compared them with the general population using the medical insurance data of South Korea. (nature.com)
  • Patients with PI are at increased risk of recurrent infections, certain malignancies, and death. (cdc.gov)
  • Reports on long term results of rhinoplasty are rare. (egms.de)
  • So, the discussion around this issue or awareness of this issue originated from reports of a rare but serious condition following AstraZeneca's COVID-19 vaccine, and this condition initially recognized was CVST in the presence of thrombocytopenia, so, blood clots in the brain with low platelets. (cdc.gov)
  • Home Article A rare case of genital myiasis in a woman with genital prolapse. (atmph.org)
  • Auerback reviewed evidence of malignancy (Figure 2). (who.int)
  • Although these fusions are rare overall, they are most commonly detected in those with NSCLC. (cancernetwork.com)
  • In addition, many european countries organize centres of excellence in order to provide optimal care for the patients with rare gynecological malignancies. (ejgo.net)