Rapid acting insulin and insulin glargine. Medical search. Frequent questions

The preprandial insulin is either rapid-acting (lispro, aspart, insulin inhaled, or glulisine) or short-acting (regular). (medscape.com)
Patients began a 6-week run-in period and were titrated with first reference insulin glargine and then insulin lispro, as needed, to ensure good diabetes control as determined by the investigator. (semgleehcp.com)
At randomization, there was a 1:1 (unit for unit) conversion of reference insulin glargine to SEMGLEE (100 U/mL of insulin glargine) and of prestudy mealtime insulin to insulin lispro. (semgleehcp.com)
Shortacting insulin (lispro, aspart and glulisine) and long-acting insulin (glargine and detemir) have been developed for the management of diabetes. (viamedica.pl)
Lispro, Humalog, Admelog, Regular Insulin): If your blood sugar is high and you need to take a correction, take ½ or 50% of your usual correction. (gastrorockies.com)
Active substance - insulin lispro. (insulin.store)
Humalog is available as a generic drug called insulin lispro . (howtotrust.com)
The generic drug is known as insulin lispro protamine/insulin lispro. (howtotrust.com)
Admelog is termed a "follow-on" to the common mealtime insulin, Humalog (insulin lispro). (howtotrust.com)
However, both ADMELOG and Humalog are: Mealtime insulins containing insulin lispro. (howtotrust.com)
Humalog is the brand-name version of insulin lispro, and Novolog is the brand-name version of insulin aspart. (howtotrust.com)
Lantus (insulin glargine [rdna origin]) and Humalog (insulin lispro [rDNA origin]) are both forms of insulin used to treat type 1 (insulin-dependent) or type 2 (non insulin-dependent) diabetes. (howtotrust.com)
Examples of short-acting (regular) insulin include Humulin R and Novolin R. Rapid-acting insulin examples are insulin glulisine (Apidra), insulin lispro (Humalog) and insulin aspart (Novolog). (diabeteshealthmatters.com)
Short-acting products like insulin lispro are generally administered just before meals to help control blood sugar levels after eating. (guidetopharmacology.org)
There's now U-200 Humalog® ( insulin lispro ), and this is what the box looks like. (medscape.com)
The current commercial batch includes rapid- and medium-acting recombinant human insulins Rinsulin ® R and Rinsulin ® NPH in vials, as well as ultra-rapid- and long-acting insulin analogues RinLis ® (insulin lispro) and RinGlar ® (insulin glargine) in cartridges. (geropharm.com)
Rapid-acting insulin analogs , insulin aspart and insulin lispro have superior insulin kinestics to regular insulin. (sugarprotalk.com)
Rapid-acting insulin, such as insulin lispro, begins working quickly and is typically taken right before or after meals. (diabetictravelinsurance.com)
Adocia's clinical pipeline includes five novel insulin formulations for the treatment of diabetes: two ultra-rapid formulations of insulin analog lispro (BioChaperone ® Lispro U100 and U200), a combination of basal insulin glargine and rapid acting insulin lispro (BioChaperone ® Combo) and two combinations of a prandial insulin with amylin analog pramlintide (M1Pram and BioChaperone ® LisPram). (fintechnews.org)
Analogs in use - aspart (NovoLog), glulisine (Apidra), and lispro (Humalog) are rapid acting insulin analogs which acts within 5-15 minutes of administration and its peak activity reaches in 30-90 minutes. (findhealthtips.com)

Two new insulin formulations were recently granted FDA approval: Tresiba® (insulin degludec), a long-acting insulin analog that can be administered once daily any time of day, and Ryzodeg®, a combination of insulin degludec and rapid-acting insulin aspart that is taken once or twice per day with any main meal. (cardiometabolichealth.org)
Fiasp - an analog to human insulin with insulin aspart in its base that can be prescribed to patients with type 1 and type 2 diabetes mellitus. (insulin.store)
NovoMix - a brand of short-acting insulins with insulin aspart as an active substance. (insulin.store)
NovoRapid (also known as Novolog) - subcutaneous insulin medication based on insulin aspart for patients with type 2 diabetes mellitus. (insulin.store)
Fiasp Insulin by Novo Nordisk is within the aspart category and found to be slightly faster than other types of insulin such as Novolog and Humalog. (howtotrust.com)
This is to inform you that Biocon Biologics Ltd., (a subsidiary of Biocon Ltd.), and Mylan (a subsidiary of Viatris Inc.) have received a positive opinion from the European Medicines Agency's Committee for Medicinal Products for Human Use (CHMP) recommending approval of the market authorization of Kixelle, a biosimilar Insulin Aspart , which is a rapid acting insulin for the treatment of Type 1 and 2 diabetes. (bioconbiologics.com)
We are extremely pleased to receive a positive opinion from the European Medicines Agency's Committee for Medicinal Products for Human Use (CHMP) for our biosimilar Insulin Aspart co-developed with Mylan. (bioconbiologics.com)
On this occasion, Adocia will be presenting Parts A and B of the Proof-of-Concept Phase I clinical trial with M1Pram, a co-formulation of pramlintide and insulin A21G that improves post-prandial glucose and body weight versus insulin aspart in type 1 diabetes. (fintechnews.org)

The basal insulin is either long-acting (glargine or detemir) or intermediate-acting (NPH). (medscape.com)
Insulin detemir is currently licensed as part of a basal-bolus insulin regimen only (Novo Nordisk, 2005). (diabetesonthenet.com)
The long-acting insulin analogues provide basal insulin levels for 24 h when administered once (glargine) or two (detemir) daily. (viamedica.pl)
Their products are based on insulin detemir for patients with diabetes type 1 and type 2. (insulin.store)
Long-acting insulins include insulin glargine (Lantus, Toujeo Solostar), insulin detemir (Levemir) and insulin degludec (Tresiba). (diabeteshealthmatters.com)
Long-acting insulin products, such as insulin glargine , insulin degludec and insulin detemir are primarily used to maintain a background level of insulin to control blood sugars between meals. (guidetopharmacology.org)
If you put a patient on this insulin, this U-300 insulin glargine or Toujeo, what you're doing is really trying to smooth out that overnight blood sugar level, reducing some of the peaks that you might find with either insulin detemir or with U-100 insulin glargine, to give them less hypoglycemia and give them a smoother basal insulin effect. (medscape.com)
It has actually been approved for use under the brand name Tresiba®, and it's somewhat different from insulin detemir. (medscape.com)
Use of long-acting insulin such as NPH, detemir , glargine will likely be done les soften and selectively. (sugarprotalk.com)
Long-acting insulin, such as insulin glargine or insulin detemir, provides a steady release of insulin and is usually taken once a day. (diabetictravelinsurance.com)
Analogs in use - glargine (brand name Lantus) and detemir (Levemir) are long acting basal insulin analogs and offers peakless background insulin for day and night. (findhealthtips.com)

Insulin glargine-yfgn (Semglee) is biosimilar to and interchangeable with insulin glargine (Lantus), a long-acting insulin analog. (optimot.de)
Semglee (Insulin Glargine-yfgn U-100) is considered interchangeable biosimilar to Lantus as of 2021 in U.S. Allows pharmacists to auto-substitute Semglee (one third Lantus cost) for Lantus (2021) Presc Lett 28(9): 51 Jun 2, 2023 · Very low blood sugar can lead to seizures, passing out, long lasting brain damage, and sometimes death. (optimot.de)
Lantus, Basaglar, Semglee, Toujeo, Insulin Glargine): Do not take any long-acting basal insulins the day before or the day of your procedure. (gastrorockies.com)
Lantus - a brand of long-acting insulins for controlling blood glucose levels in people with diabetes mellitus type 1 and 2. (insulin.store)
Compared to long-acting insulins like Lantus (insulin glargine), rapid-acting insulins are more suitable for controlling blood sugar levels before and after a meal. (howtotrust.com)
Basaglar (insulin glargine)- Basaglar is essentially Lilly's version of Lantus (made by Sanofi-Aventis). (howtotrust.com)
The only difference from Lantus is the Lilly KwikPen delivery system also found on other Lilly short-acting insulins like Humulin and Humalog. (howtotrust.com)
Is there a substitute for Lantus insulin? (howtotrust.com)
What insulin is comparable to Lantus? (howtotrust.com)
Basaglar is biologically similar to Sanofi's basal insulin Lantus (insulin glargine), including the same protein sequence and a similar glucose-lowering effect. (howtotrust.com)
As a visual, it comes in this box, which is this light green color with some black polka dots, and the pen looks quite different compared with that gray glargine or Lantus® insulin that you're used to. (medscape.com)

Humalog is an insulin brand by Eli Lilly and Company manufacturer for patients with type 1 and type 2 diabetes. (insulin.store)
Because Admelog uses the same type of insulin as Lilly's Humalog , it can be thought of as a sort of "me too" version of Humalog. (howtotrust.com)
A difference is that Humalog is usually given together with another long-acting insulin. (howtotrust.com)
Humalog is a fast-acting insulin used to treat type 1 (insulin-dependent) diabetes in adults. (howtotrust.com)

There is another long-acting basal insulin that's going to come on the market called insulin degludec . (medscape.com)
The utilization of long-acting BIs, longer-acting BIs, biosimilar BIs, and insulin degludec (IDeg-100) were informed by IQVIA data and internal forecasting at Sanofi. (bvsalud.org)
However, insulin-based treatments often come with the risk of hypoglycemic episodes, which can lead to increased utilization of healthcare resources (HCRU) and have a negative impact on costs.This study aimed to assess the budgetary impact of higher market shares of longer-acting basal insulins (specifically insulin glargine Gla-300) compared to long-acting basal insulins, insulin glargine biosimilars, and insulin degludec (IDeg) in the treatment of T2D. (bvsalud.org)

Basaglar - long-acting insulin for diabetes mellitus type 1 and type 2. (insulin.store)

Toujeo® (insulin glargine U300) was approved earlier this year and Afrezza®, the only inhaled insulin available in the US, reached pharmacies in February. (cardiometabolichealth.org)
One of the newer insulin products is called Toujeo®, and it's actually insulin glargine , which we're used to, but instead of being U-100, it's U-300. (medscape.com)

Levemir - an insulin medication brand by Novo Nordisk manufacturer. (insulin.store)
Levemir is a long-acting human insulin analog used to treat diabetes in adults and children. (howtotrust.com)

Semglee ( insulin glargine injection) is a long-acting human insulin analog indicated to improve glycemic control in adults and pediatric patients with type 1 diabetes mellitus and in adults with type 2 diabetes mellitus. (rxlist.com)
The dose of Semglee is individualized based on the patient's metabolic needs, blood glucose monitoring, glycemic control, type of diabetes , and prior insulin use. (rxlist.com)
The use of Semglee for this indication is based upon an adequate and well-controlled trial of another insulin glargine product in pediatric patients age 6 to 15 years with type 1 diabetes and additional data in adults with type 1 diabetes. (rxlist.com)
Our Semglee (insulin glargine injection), for Subcutaneous Use Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication. (rxlist.com)
Semglee contains insulin glargine as a sterile solution for subcutaneous use. (rxlist.com)
Semglee consists of insulin glargine dissolved in a clear, colorless, sterile solution. (rxlist.com)
In the INSTRIDE 1 clinical trials, SEMGLEE demonstrated non-inferiority to reference insulin glargine in both adult and pediatric patients with Type 1 Diabetes. (semgleehcp.com)
In the INSTRIDE 1 trial, the mean change in HbA1c from the baseline to week 24 among Type 1 diabetic patients was not non-inferior between SEMGLEE and the reference insulin glargine groups. (semgleehcp.com)
Change in 7-point self-monitored blood glucose (SMBG) profile from baseline to week 24 in all and insulin-naive patients with SEMGLEE and reference insulin glargine. (semgleehcp.com)

Insulin analogs were created to more closely mimic the normal physiology of the pancreas and improve pharmacokinetics. (medpagetoday.com)
But these insulins largely have been supplanted by rapid- or long-acting "analogs," in which the insulin molecule has been modified, leading to patent protections for drug companies. (medpagetoday.com)
Depending on the type of diabetes mellitus you have, you might either need or do not need to take insulin-based medications or their analogs. (insulin.store)
Due to the fact that insulin-based medications and their analogs belong to prescribed preparations, you would need valid prescriptions from your health care practitioner in order to buy them from pharmaceutical companies. (insulin.store)
Since the DCCT was conducted, significant advances in diabetes management have occurred, including newer and more physiologic insulin analogs, sophisticated blood glucose monitoring, and insulin delivery technologies such as continuous subcutaneous insulin pump therapy (CSII) and continuous glucose monitoring (CGM). (cdc.gov)
in fact, most of these longer-acting analogs cause less nocturnal hypoglycemia. (medscape.com)
Also, we briefly mention newer insulin analogs and alternate insulin delivery methods, as this topic is discussed at length by colleagues in chapter 5 of this yearbook. (docksci.com)
Regular insulin, when given SQ, requires at least 30 minutes for onset of action, therefore, use of rapid-acting analogs may be preferable. (sugarprotalk.com)
Adocia preclinical pipeline includes bi-hormonal combinations for diabetes treatment: a combination of rapid acting insulin analogs and pramlintide (BioChaperone ® AsPram), a combination of insulin glargine with GLP-1 receptor agonists (BioChaperone ® Glargine Liraglutide). (fintechnews.org)

The human insulin protein is composed of 51 amino acids, and has a molecular mass of 5808 Da. (wikipedia.org)
Insulin from non-human animal sources differs somewhat in effectiveness (in carbohydrate metabolism effects) from human insulin because of these variations. (wikipedia.org)
Porcine insulin is especially close to the human version, and was widely used to treat type 1 diabetics before human insulin could be produced in large quantities by recombinant DNA technologies. (wikipedia.org)
Insulin glargine differs from human insulin in that the amino acid asparagine at position A21 is replaced by glycine and two arginines are added to the C-terminus of the B-chain. (rxlist.com)
Chemically, insulin glargine is 21 A -Gly-30 B a-L-Arg-30 B b-L-Arg-human insulin and has the empirical formula C 267 H 404 N 72 O 78 S 6 and a molecular weight of 6063. (rxlist.com)
Later, in the 1970s synthetic human insulin was developed, and in 1982 human synthetic insulin hit the market in the form of Eli Lily's Humulin. (medpagetoday.com)
Regular (rapid-acting human insulin) is still available today, as is intermediate-acting Neutral Protamine Hagedorn (NPH) insulin. (medpagetoday.com)
While insulin was originally developed using the pancreas of a pig, synthetic human insulin was developed in the late 1970s using recombinant DNA technology, in which genes are inserted into bacteria to produce the hormone. (medpagetoday.com)
Eli Lilly's Humulin was the first synthetic human insulin available on the market in 1982. (medpagetoday.com)
Regular, rapid-acting human insulin like Humulin R and Novolin R is still available today, as is Neutral Protamine Hagedorn (NPH) insulin, an intermediate-acting formulation (typically branded Humulin N or Novolin N). (medpagetoday.com)
Short-acting insulin analogues are an alternative to regular human insulin before meals. (viamedica.pl)
The active substance is regular human insulin (human genetically engineered). (insulin.store)
Novolin is an insulin medication based on the regular human insulin NPH insulin. (insulin.store)
The structure of approved drug insulin regular (which the link to DrugBank outlines) is identical to native human insulin. (guidetopharmacology.org)
While recombinant human insulin was approved by the FDA in 1982, insulin from pigs was used for several decades prior to this date. (guidetopharmacology.org)
Many recombinant forms of human insulin have been approved for clinical use. (guidetopharmacology.org)
They can be identical in sequence to human insulin or can be modified in ways which affect their speed of action. (guidetopharmacology.org)

Is novolin and NovoLog the same insulin? (howtotrust.com)
The main difference between these two insulins is that Novolog 70/30 - contains an intermediate acting and a very fast acting insulin, whereas Novolin 70/30 contains an intermediate acting insulin and a short acting insulin. (howtotrust.com)

Food and Drug Administration queens da missing 2023 showtimes near regal pavilion and rpx There are multiple types of insulin available. (optimot.de)
Your doctor may prescribe two types of insulin to be injected at once for diabetes . (diabetesprohelp.com)
Basically, there are two main types of insulin pens: disposable and reusable. (insulin.store)
Choose a province below to see coverage of diabetes tech and types of insulin in your province. (arrivalsdepartures.com)
Some are treated with injections of different types of insulin (rapid- or slow-acting), particularly after failure of first-line oral antidiabetic drugs (OADs) alone. (carenity.us)

Glucose production and secretion by the liver is strongly inhibited by high concentrations of insulin in the blood. (wikipedia.org)
Beta cells are sensitive to blood sugar levels so that they secrete insulin into the blood in response to high level of glucose, and inhibit secretion of insulin when glucose levels are low. (wikipedia.org)
Insulin production is also regulated by glucose: high glucose promotes insulin production while low glucose levels lead to lower production. (wikipedia.org)
Insulin enhances glucose uptake and metabolism in the cells, thereby reducing blood sugar level. (wikipedia.org)
The secretion of insulin and glucagon into the blood in response to the blood glucose concentration is the primary mechanism of glucose homeostasis. (wikipedia.org)
But insulin is still secreted into the blood in response to the blood glucose. (wikipedia.org)
The insulin toxin, closer in structure to fishes' than to snails' native insulin, slows down the prey fishes by lowering their blood glucose levels. (wikipedia.org)
Optimal diabetic control requires frequent self-monitoring of blood glucose levels, which allows rational adjustments in insulin doses. (medscape.com)
All patients with type 1 diabetes should learn how to self-monitor and record their blood glucose levels with home analyzers and adjust their insulin doses accordingly. (medscape.com)
Most require 2 or more injections of insulin daily, with doses adjusted on the basis of self-monitoring of blood glucose levels. (medscape.com)
These agents stimulate insulin secretion from pancreatic cells, lowering blood glucose levels. (medscape.com)
It mimics endogenous insulin patterns, restores early insulin secretion, and controls mealtime glucose surges. (medscape.com)
These agents stimulate peripheral use of glucose as stimulated by insulin. (medscape.com)
Activation of PPAR-gamma receptors regulates insulin-responsive gene transcription involved in glucose production, transport, and utilization, thereby reducing blood glucose concentrations and reducing hyperinsulinemia. (medscape.com)
Diabetes mellitus is a metabolic disease characterized by high blood sugar (glucose) levels that result from defects in insulin secretion or the body's ability to use insulin. (medicinenet.com)
Normally, blood glucose levels are tightly controlled by insulin, a hormone produced by the pancreas. (medicinenet.com)
Insulin lowers the blood glucose level. (medicinenet.com)
When the blood glucose elevates (for example, after eating food), insulin is released from the pancreas. (medicinenet.com)
This release of insulin promotes the uptake of glucose into body cells. (medicinenet.com)
Secondary Endpoint: Included changes from baseline in basal insulin dose as well as fasting plasma glucose (FPG), SMBG and immunogenicity. (semgleehcp.com)
Secondary Endpoints: Change from baseline in fasting plasma glucose (FPG), eight-point self-monitored blood glucose (SMBG) profile and insulin dose per unit body weight, and immunogenicity at week 36, in addition to occurrence of hypoglycaemic events (30-day rate), nocturnal hypoglycaemic events, and adverse events (AEs). (semgleehcp.com)
The availability of these new insulin analogues has the potential to significantly improve long-term control over blood glucose in diabetic patients. (viamedica.pl)
Fully automated continuous glucose monitoring systems integrated with insulin pumps operating in closed-loop model, requiring no patient assistance, are still being researched. (viamedica.pl)
The term "sliding scale" refers to the progressive increase in the pre-meal or nighttime insulin dose, based on pre-defined blood glucose ranges. (howtotrust.com)
Insulin is a hormone needed to allow sugar (glucose) to enter cells to produce energy. (diabeteshealthmatters.com)
In type 1 diabetes, there's no insulin to let glucose into the cells, so sugar builds up in your bloodstream. (diabeteshealthmatters.com)
When other treatments prove ineffective in achieving adequate glucose control, insulin-based therapy becomes necessary. (bvsalud.org)
And there are many different rarer forms of diabetes corresponding to type 3c and Latent Autoimmune Diabetes in Adults too Diabetes is a critical situation where your blood glucose degree is simply too high It can occur when your body does not produce enough normal range of blood sugar non diabetic insulin or the insulin it produces is not effective. (scobo.pro)
Sometimes babies of mothers with gestational diabetes develop low blood sugar shortly after birth because their very own insulin production is excessive Prompt feedings and sometimes an intravenous glucose solution can return the infant s blood sugar degree to regular As a world leader in diabetes care, Abbott is constantly working to deliver the very best high quality products and unwavering support to our customers. (scobo.pro)
Hemoglobin A1c Test Hemoglobin A1c or HbA1c is a protein on the floor of pink blood cells The HbA1c take a look at is used to observe blood sugar ranges in What Can A Diabetic With Kidney Disease Eat people with sort 1 and sort 2 diabetes over time HbA1c levels can be affected by insulin use, fasting, glucose consumption , or a mix of these and different components. (musicproductionhq.com)
Type 1 diabetes also referred to as insulin dependent diabetes mellitus In this case, the beta Can Type 1 Diabetes Cause Vertigo cells of the pancreas which produce insulin are destroyed because of autoimmune irregularity Our physique needs glucose because the principal supply of power. (musicproductionhq.com)
those with diabetes and an insulin resistance cannot achieve back the identical power from meals because of the glucose not being able to be damaged down correctly into energy Your yearly doctor s appointment is an excellent time to verify in in your blood glucose levels This is very true if your age , weight, or family historical past put you at larger risk for creating diabetes in general. (esaunggul.ac.id)
Long-acting insulin preparations are used by patients with type 1 and insulin-deficient type 2 DM to provide a low level of background insulin to suppress hepatic gluconeogenesis and prevent hyperglycemia due to excess endogenous glucose production. (sugarprotalk.com)
These insulin preparations wil likely have a limited role in management of acute hyperglycemia but may be needed in cases of newly diagnosed DM where glucose toxicity is present. (sugarprotalk.com)
Other classes of non-insulin glucose-lowering agents such as DDP-4 inhibitors or TZDs are likely best not started in the urgent care setting because of cost, complexity, and side-effect issues. (sugarprotalk.com)
Metformin is a pill that can reduce excess release of glucose from the liver, acting as an "insulin sensitizer," explains Dungan. (everydayhealth.com)
This is the arrangement of administration of different kind of insulin (like basal insulin and bolus insulin) into the body at different time in a day so that the blood glucose level before and after meal can be efficiently controlled. (findhealthtips.com)
Any disturbance in amount of basal insulin at any instant can hike the blood glucose level and increase the production of ketones or the acid by products of fat burning process. (findhealthtips.com)
It happens due the increased production of blood sugar rising hormone at night which leads to high requirement of basal insulin in morning and with daytime activities the blood glucose level comes down which requires needs less insulin. (findhealthtips.com)
We aim to support the T1D community to increase both public and private coverage for advanced glucose monitors (Flash CGM and Continuous Glucose Monitors) and insulin pumps. (arrivalsdepartures.com)
Avoiding hypoglycemia requires familiarity with the patient's daily oral intake and understanding of the insulin's onset of action, peak (when insulin is at its highest glucose lowering effect) and duration of effect. (enclarapharmacia.com)
People with type 1 diabetes require insulin injections and frequent monitoring of glucose levels. (msdmanuals.com)
Monitoring Diabetes Treatment Diabetes mellitus is a disorder in which the body does not produce enough or respond normally to insulin, causing blood sugar (glucose) levels to be abnormally high. (msdmanuals.com)
People can release additional doses of insulin as needed for meals or to correct high blood glucose levels. (msdmanuals.com)
With these systems (sometimes called an artificial pancreas), an algorithm is used to calculate and automatically deliver baseline insulin doses through an insulin pump based on input from a continuous glucose monitor. (msdmanuals.com)

Frederick Banting and Charles Best, working in the laboratory of John Macleod at the University of Toronto, were the first to isolate insulin from dog pancreas in 1921. (wikipedia.org)
Type 1 diabetes is a chronic illness characterized by the body's inability to produce insulin due to the autoimmune destruction of the beta cells in the pancreas. (medscape.com)
Repaglinide is a meglitinide analogue, a secretagogue that acts on the pancreas to stimulate the release of insulin. (medscape.com)
In type 1 diabetes , the pancreas cannot produce insulin. (medicinenet.com)
Insulin was originally identified and isolated in the 1920s, pig pancreas was the original primary source. (medpagetoday.com)
Type 1 diabetes, once known as juvenile diabetes or insulin-dependent diabetes, is a chronic condition in which the pancreas produces little or no insulin. (diabeteshealthmatters.com)
Usually, the body's own immune system - which normally fights harmful bacteria and viruses - mistakenly destroys the insulin-producing (islet, or islets of Langerhans) cells in the pancreas. (diabeteshealthmatters.com)
Insulin is a hormone that comes from a gland situated behind and below the stomach (pancreas). (diabeteshealthmatters.com)
The pancreas secretes insulin into the bloodstream. (diabeteshealthmatters.com)
As your blood sugar level drops, so does the secretion of insulin from your pancreas. (diabeteshealthmatters.com)
These drugs "cause the insulin-producing cells of the pancreas to produce insulin almost constantly, which means they increase the risk of low blood sugar and for weight gain," says Daniel Einhorn, MD , an internist at Scripps Memorial Hospital in La Jolla, California. (everydayhealth.com)
Flexible insulin therapy is mainly aimed at patients with type 1 diabetes who need a daily supply of insulin (a hormone secreted by the pancreas that regulates blood sugar levels). (carenity.us)
The aim of flexible insulin therapy is to mimic the natural insulin production of a healthy pancreas . (carenity.us)

Discharge plans should include appropriate choice and dosing of insulin regimens and interventions to prevent recurrence of DKA. (lww.com)
Learn more about these newest options and how they can help you customize your patients' insulin regimens at the 10th Annual CMHC . (cardiometabolichealth.org)
Among the new treatment regimens that have emerged, the development of rapid- and long-acting insulin analogues using recombinant DNA technology represents a major advance in the treatment of diabetes (Barrio Castellanos, 2005). (diabetesonthenet.com)
Sliding scale insulin regimens approximate daily insulin requirements. (howtotrust.com)
Multiple daily injections that include a combination of a long-acting insulin combined with a rapid-acting insulin more closely mimic the body's normal use of insulin than do older insulin regimens that only required one or two shots a day. (diabeteshealthmatters.com)
To examine the patterns and associations of insulin regimens and change in regimens with clinical outcomes in a diverse population of children with recently diagnosed type 1 diabetes. (cdc.gov)
Insulin regimens and change in regimen compared with the initial visit were categorized as more intensive (MI), no change (NC), or less intensive (LI). (cdc.gov)
We examined relationships between insulin regimens, change in regimen, and outcomes including A1C and fasting C-peptide. (cdc.gov)
Insulin regimens were intensified over time in over half of participants but varied by sociodemographic domains. (cdc.gov)
Current recommendations from the American Diabetes Association (ADA) and International Society for Pediatric and Adolescent Diabetes endorse the use of intensive insulin regimens in most pediatric patients. (cdc.gov)
However, it is unclear whether intensive insulin regimens used in clinical pediatric diabetes care result in different A1C outcomes ( 4 , 5 ). (cdc.gov)
The SEARCH for Diabetes in Youth study has reported that insulin treatment regimens were cross-sectionally associated with sociodemographic, clinical, and metabolic characteristics among youth with type 1 diabetes ( 6 ). (cdc.gov)
Sociodemographic factors were strongly associated with insulin regimen used, with participants more likely to be using intensive regimens, such as CSII, if they were of non-Hispanic white race/ethnicity and from families with higher income and higher parental education, and had private health insurance. (cdc.gov)

Jul 29, 2021 · Article Officials with the FDA have approved the first interchangeable biosimilar insulin product for patients with type 1 or type 2 diabetes mellitus. (optimot.de)
After this, we're going to get biosimilar insulin, and these products will have different names. (medscape.com)
Biosimilar insulin is sort of like generic insulin, but there is no "generic" insulin per se because biosimilars require a lot more testing for regulatory approval. (medscape.com)
There will be biosimilar insulin glargine, for instance, and these insulin products will be coming out in the future, but with different names. (medscape.com)
We will have to wait and see what the pricing structure becomes of the biosimilar insulin products vs the traditional branded insulin products vs these newer, even more stable insulin products that are coming on the market. (medscape.com)

These agents include chlorpropamide and tolbutamide (first-generation), as well as glipizide, glyburide, and glimepiride (second-generation), are secretagogues (ie, medications that stimulate insulin secretion). (medscape.com)

Treated with once-daily insulin glargine for more than 3 months and with HbA1c ≤9.5% at screening. (semgleehcp.com)

In addition, the rapid-acting insulin analogues offer convenience as well as clinical benefits - they are injected immediately before a meal rather than 30-45 minutes in advance (Lepore et al, 2000). (diabetesonthenet.com)
Modern pre-mixes manufactured using rapid-acting insulin analogues offer better postprandial control and are therefore replacing the traditional products (Garber, 2006). (diabetesonthenet.com)
In recent years, insulin analogues are the benefits of the use in functional intensive insulin therapy for the treatment of diabetes. (viamedica.pl)
These new short-acting insulin analogues show more rapid onset of activity and a shorter duration of action. (viamedica.pl)
In addition, these insulin analogues can be administered immediately before a meal. (viamedica.pl)
The use of these long-acting insulin analogues appears to be associated with a reduced incidence of hypoglycemia, especially at night. (viamedica.pl)

The term "sliding scale" refers to the progressive increase in pre-meal or nighttime insulin doses . (howtotrust.com)
Requirement - It is required around mealtime and its doses should be timed so that the insulin peak activity matches the timing of peak time of blood sugar increase. (findhealthtips.com)
Indeed, flexible insulin therapy enables diabetic patients to understand their insulin needs and adapt their insulin doses to their lifestyle (food intake, physical activity, etc. (carenity.us)
Note that in the case of insulin pumps , these are small doses of rapid-acting insulin that are delivered continuously at regular intervals ( basal rate ) throughout the day. (carenity.us)
How are insulin doses determined? (carenity.us)
The goal of flexible insulin therapy is to be as autonomous as possible in order to anticipate insulin doses (for example, according to the activities one plans to do during the day) and to treat hypoglycemia. (carenity.us)
To do this, it is necessary to know how to determine the basal and rapid-acting insulin doses. (carenity.us)
It is therefore this evaluation of the rapid-acting insulin doses administered and blood sugar levels while fasting that makes it possible to estimate the dose of basal insulin required. (carenity.us)
When starting treatment, bolus insulin doses are determined from test meals with a 40g carbohydrate breakfast, an 80g carbohydrate lunch and a 60g carbohydrate dinner. (carenity.us)

Insulin glargine is a recombinant human long-acting insulin analog [see CLINICAL PHARMACOLOGY ]. (rxlist.com)

Low blood potassium may happen with this medicine (insulin glargine vials). (optimot.de)
Insulin analog vials are $150 or more out-of-pocket (GoodRx.com), and pens are more than $300 a pack, out-of-pocket. (medpagetoday.com)
Media reports have detailed other cases of patients who couldn't afford their insulin -- not surprisingly, since some insulin products retail for more than $250 per vial and patients can use several vials per month. (medpagetoday.com)
10ml adaptor for insulin vials. (insujet.com)
Vials, pens, and cartridges are available at Insulin.Store. (insulin.store)

It was formerly known as adult-onset diabetes or non-insulin-dependent diabetes . (medicinenet.com)
These have the most rapid onset of action as well as a shorter duration of action than other insulin categories. (easynotecards.com)

Insulin glargine-yfgn injection is a long-acting type of insulin that works slowly, over about 24 hours. (optimot.de)
Billing the wrong type of insulin for a pump can also result in large audit recoupments. (paasnational.com)
What Type of Insulin Is Best for My Diabetes? (howtotrust.com)
The cost of insulin can vary depending on factors such as the type of insulin, brand name or generic, and the pharmacy where it is purchased. (diabetictravelinsurance.com)

Long-Acting Insulins (ex. (gastrorockies.com)

So, these newer long-acting insulin products give you less hypoglycemia and a longer action. (medscape.com)

Thomas C. Blevins, MD, ECNU, FACE, FNLA, leads the discussion on potential challenges to the adoption of biosimilars in clinical practice, such as for insulin glargine-yfgn in diabetes management, and discusses the importance of patient and provider education. (optimot.de)
Impact of Interchangeable Insulin Biosimilars on Cost of Biologics. (optimot.de)
It's hard to make these insulin products, so the biosimilars have actually been tested more than a routine generic medication would be and have been shown to be similar in activity as the original parent compound. (medscape.com)
In the model base case, 24% of patients switched from long-acting BIs to insulin glargine biosimilars, IDeg-100, and other longer-acting BIs (Gla-300) by projected year 3. (bvsalud.org)

McCormack and McElduff, 2004), such mixes do not closely match the profile of endogenous insulin and studies comparing them with a basal insulin and oral antidiabetic agent (OAD) combination have produced mixed findings (Janka et al, 2005). (diabetesonthenet.com)

the insulin pump . (medicinenet.com)
When used in conjunction with an insulin pump, it adds another layer of complexity. (paasnational.com)
One of the reasons insulin claims for Medicare Part D patients are commonly audited is because the PBMs can't identify if the patient is self-administering (and Part D is responsible) or using in a pump (where Part B may be responsible) at adjudication. (paasnational.com)
The pharmacy should always verify with the patient or prescriber if insulin is being used in a pump. (paasnational.com)
See the tips below for which insulin types should, and should not, be used in an insulin pump. (paasnational.com)
You'll need to receive it either through injections or an insulin pump. (diabeteshealthmatters.com)
An insulin pump. (diabeteshealthmatters.com)
Younger age, continuous subcutaneous insulin pump therapy, and change to MI were associated with higher probability of achieving target A1C levels. (cdc.gov)
The variation of the daily insulin requirements after pump placement was 12.75 units of insulin (p = 0.015), equivalent to a decrease of 0.20 units/kg (p = 0.023). (unboundmedicine.com)
In response to the public, the government will no longer be making changes to the Insulin Pump Therapy Program. (arrivalsdepartures.com)
meet and continue to meet the clinical criteria as set out in the Insulin Pump Therapy Program - Clinical Criteria. (arrivalsdepartures.com)
complete a pre-insulin pump information session. (arrivalsdepartures.com)
complete an insulin pump therapy (IPT) education plan. (arrivalsdepartures.com)
It consists of basal-bolus insulin therapy , administered via multiple injections (usually 4: at breakfast, lunch, dinner and before going to bed) using insulin pens or automatically by an insulin pump at regular intervals throughout the day. (carenity.us)
Another device is an insulin pump, which pumps insulin continuously from a reservoir through a small cannula (hollow plastic tube) left in the skin. (msdmanuals.com)

The pathogenesis of type 2 diabetes is not well understood but reduced population of islet beta-cells, reduced secretory function of islet beta-cells that survive, and peripheral tissue insulin resistance are known to be involved. (wikipedia.org)
Metformin reduces insulin resistance (ie, metformin is an insulin sensitizer). (medscape.com)
Insulin resistance means that although the body can produce insulin, the body's cells do not respond properly to the insulin that is made. (medicinenet.com)
Type 2 diabetes is more a result of insulin resistance (cells not being able to use insulin effectively or at all. (medicinenet.com)
Sugar can be notably harmful to well being when consumed in giant amounts with excess energy and fat This trifecta can lead to insulin resistance, increased belly fats, whole body fat , and fats saved outdoors of fatty how to treat high blood sugar emergency tissues in the liver and muscle Over time, insulin resistance and further fats mass can lead to metabolic syndrome, type 2 diabetes , and heart problems. (musicproductionhq.com)
Frequent testing with your blood sugar meter and taking motion when blood sugar is trending low can stop a severe low and hold your life on observe If you might have prediabetes or diabetes, you could have insulin resistance or an incapability to produce insulin This means your body has issue regulating blood sugar levels on its own. (musicproductionhq.com)
May cause resumption of ovulation and increase risk of pregnancy in premenopausal anovulatory women with insulin resistance. (conduent.com)
Alternatively, for high-risk women or in areas in which the prevalence of insulin resistance is 5% or higher (eg, the southwestern and southeastern United States), a 1-step approach can be used by proceeding directly to the 100-g, 3-hour OGTT. (medscape.com)

Rosiglitazone is an antidiabetic agent (thiazolidinedione derivative) that improves glycemic control by improving insulin sensitivity. (medscape.com)

Decreased or absent insulin activity results in diabetes mellitus, a condition of high blood sugar level (hyperglycaemia). (wikipedia.org)
In diabetes mellitus type 1, the beta cells are destroyed by an autoimmune reaction so that insulin can no longer be synthesized or be secreted into the blood. (wikipedia.org)

Patients with type 1 diabetes require lifelong insulin therapy. (medscape.com)
The best drug treatment for treating hyperglycaemia/diabetes in hospitalised patients is insulin and we make recommendations for adapt the theoretical insulin action to the nutrition infusion regimen. (isciii.es)
It is the longest-acting sulfonylurea, present in blood longer than 24 hour in many patients, and longer in patients with renal insufficiency. (medscape.com)
Now Viewing.For insulin-naïve patients. (optimot.de)
In patients with diabetes, the absence of insufficient production or lack of response to insulin causes hyperglycemia . (medicinenet.com)
In patients with diabetes, insulin is comparable to the oxygen we breath. (medpagetoday.com)
Patients, clinicians, policy makers, and advocates need to continue to put pressure on industry to make insulin affordable to people who need it. (medpagetoday.com)
The disease may be controlled by lifestyle modifications, oral drug therapy, and/or insulin, but patients are not necessarily dependent on insulin therapy. (easynotecards.com)
558 patients with type 1 diabetes, with or without prior insulin use: 336 males and 222 females, aged 18-65 years, BMI 18.5-35kg/m 2 . (semgleehcp.com)
The approvals add to a growing list of insulin options for patients with diabetes. (cardiometabolichealth.org)
In recent years treatment with insulin pumps has been used more frequently in the pediatric patients and in the treatment of diabetes in pregnancy. (viamedica.pl)
This short-acting insulin may be prescribed to patients with diabetes type 1 and type 2 in combination with long-acting insulin. (insulin.store)
My patients get confused if I say this is an extra-concentrated insulin glargine. (medscape.com)
MATERIALS AND METHODS: An economic model for a hypothetical one million U.S. health-plan population was developed to assess the budgetary impact of therapeutic interchanges in either direction between the two long- and longer-acting basal insulins (BIs) for patients with type 2 diabetes over a three-year model horizon. (bvsalud.org)
Budgetary reductions were achieved by switching patients from long-acting BIs to Gla-300. (bvsalud.org)
The exorbitant prices of insulin have had a profound impact on patients across the country. (diabetictravelinsurance.com)
A good insulin program can help you in controlling your diabetes very successfully but many patients are not educated well about how to select the best insulin program which can meet their requirements. (findhealthtips.com)
This method may also be suitable for certain patients with type 2 diabetes (formerly known as insulin-dependent diabetes ). (carenity.us)
How should insulin be adapted for patients with advanced disease? (enclarapharmacia.com)

The basal-bolus insulin regimen is the most common one for people with type 1 diabetes. (diabetesonthenet.com)
It involves long-acting (basal) insulin, which is injected at night, and an additional bolus injection of short-acting insulin before each meal. (diabetesonthenet.com)
An alternative regimen to basal-bolus for people with type 2 diabetes is twice-daily pre-mixed insulin in which traditional short- or rapid-acting insulin and intermediate-acting basal insulin are combined in one syringe. (diabetesonthenet.com)
Each insulin has its benefits and drawbacks and therefore a right combination of basal and bolus insulin is necessary for controlling diabetes. (findhealthtips.com)
Since you are not taking any bolus insulin during lunchtime and the intermediate acting insulin is also wearing off then you can experience high blood sugar level immediately after eating. (findhealthtips.com)

In recent years more and more frequently the method of multiple daily injections (MDI) of insulin is being replaced by the method of continuous subcutaneous insulin infusion (CSII). (viamedica.pl)
If you choose injections, you'll likely need a mixture of insulin types to use throughout the day and night. (diabeteshealthmatters.com)
A regimen of three or more insulin injections a day has been shown to improve blood sugar levels. (diabeteshealthmatters.com)
Continuous subcutaneous insulin infusion (CSII) and multiple daily injections (MDI) represent two strategies of intensive insulin therapy, obtaining a strict metabolic control. (unboundmedicine.com)
An insulin pen, which contains a cartridge that holds the insulin , is a convenient way for many people to carry and use insulin , especially for people who take several injections a day outside the home. (msdmanuals.com)

The Adaptor 10mL is used to transport the insulin from a 10mL vial into the Nozzle. (insujet.com)
The Adaptor must be replaced with each new insulin vial. (insujet.com)
Extremely thin people may need to angle the needle more in order to avoid injecting into the muscle, which can be very painful.Never shake a vial or insulin pen. (diabetesprohelp.com)

The InsuJet needle-free insulin injection system does not include insulin. (insujet.com)
Intermediate-acting insulins include insulin NPH (Novolin N, Humulin N). (diabeteshealthmatters.com)

Improved Pharmacokinetic and Pharmacodynamic Profile of Rapid-Acting Insulin Using Needle-Free Jet Injection Technology. (insujet.com)
This handheld, simple-to-use injection device, is ideal for self-injection of insulin. (insujet.com)
Sterile nozzles are used to temporarily store the required dose of insulin prior to injection. (insujet.com)
Sterile adaptors are needed to transfer insulin from standard containers to the nozzle prior to every injection. (insujet.com)
That adds up to about 5000 injection depending on your insulin therapy. (insujet.com)
Because you will be injecting insulin on a regular basis for diabetes, you need to know where to inject it and how to rotate your injection sites. (diabetesprohelp.com)
If the same injection site is used over and over again, you may develop hardened areas under the skin that keep the insulin from being used properly. (diabetesprohelp.com)
its major disadvantage is that it causes a peak in plasma insulin concentration 1-2 hours after injection, unlike the short-lived prandial response seen in people without diabetes (Kumar and Clark, 1998). (diabetesonthenet.com)
A cartridge is an insulin device that is used together with an insulin pen to perform an insulin injection. (insulin.store)
Intermediate insulin - It is used to cover meals which are consumed after 4-6 hours after the injection. (findhealthtips.com)
It was a standard program which uses regular insulin and it is very simple to use because only two injection were required for the day. (findhealthtips.com)
This afternoon high insulin condition can also arise if your basal insulin dissipates before dinnertime injection. (findhealthtips.com)
This plan overcomes the shortcomings of the beater insulin program and you require three injection for the day. (findhealthtips.com)

In addition, insulin glargine's constant and peakless profile allows its flexible administration - whereas traditional insulins must be injected at bedtime - and it has a lower inter-subject variability than short-acting insulins, making accurate dosing and titration easier (Lepore et al, 2000). (diabetesonthenet.com)
Novolin R and Novolin N are currently the cheapest traditional insulins, with average unit prices of around $0.10. (howtotrust.com)

Humulin - an insulin brand by Eli Lilly and Company manufacturer. (insulin.store)

Adocia (Euronext Paris: FR0011184241 - ADOC) (Paris:ADOC), a clinical-stage biopharmaceutical company focused on the treatment of diabetes and other metabolic diseases with innovative formulations of proteins and peptides, announced today that it will deliver an oral presentation covering proprietary M1Pram (ADO09) pramlintide insulin at the 57th Annual Meeting of the European Association for the Study of Diabetes (EASD), being held virtually during September 27th - October 1st, 2021. (fintechnews.org)

In this article Phillip Pickstock describes a retrospective questionnaire analysis assessing the effect of an insulin regimen change on treatment satisfaction and general wellbeing. (diabetesonthenet.com)
Although intensification of insulin regimen is preferred, choice of insulin regimen must be individualized based on the child and family's ability to comply with the prescribed plan. (cdc.gov)
Flexible insulin therapy (also known as intensive insulin therapy) is a therapeutic regimen for diabetes which is based upon tight management of blood sugar levels so as to keep them closer to the levels of someone who does not have diabetes. (carenity.us)

We as physicians can keep these costs in mind when prescribing insulin, but should also consider the safe utility of older insulin formulations (supported by Lipska et al in an article published in JAMA July 2018) at a fraction of the cost. (medpagetoday.com)
The last few years have seen several new developments in the treatment and management of diabetes, including new insulin formulations and delivery methods, simpler blood sugar tests and people with diabetes taking greater responsibility for the management of their condition (Naess and Eriksen, 2002). (diabetesonthenet.com)
Different insulin formulations have different price points, with newer and more technologically advanced options often coming at a higher cost. (diabetictravelinsurance.com)

TY - JOUR T1 - [Continuous subcutaneous insulin infusion]. (unboundmedicine.com)

3ml adaptor for insulin cartridges and disposable insulin pens. (insujet.com)
This type of long-acting insulin is available at Insulin.Store in the form of pens and cartridges. (insulin.store)
Insulin pens look similar to ink pens and are available in disposable or refillable varieties. (diabeteshealthmatters.com)

If you withdraw too much cloudy insulin, the total dosage in the syringe must be discarded. (diabetesprohelp.com)
Be careful not to push any of the clear insulin from the syringe into the cloudy insulin. (diabetesprohelp.com)
If there are large air bubbles after mixing the insulin in the syringe, discard this dosage and start the procedure again. (diabetesprohelp.com)
Injecting insulin into the thigh is easy, and the same method can be used whether you are using a syringe or an insulin pen. (diabetesprohelp.com)
You can use a fine needle and syringe or an insulin pen to inject insulin under your skin. (diabeteshealthmatters.com)

regular- or short-acting. (optimot.de)
Rapid-Acting and Regular Short-Acting Insulin (ex. (gastrorockies.com)
Is short-acting insulin the same as regular insulin? (howtotrust.com)
Regular insulin (Novolin R) is also known as short-acting insulin. (howtotrust.com)
Some of you may have heard of U-500 insulin, which is basically a 5-fold more concentrated regular insulin, and we reserve it for people who are very insulin resistant. (medscape.com)
Short-acting insulin, like regular insulin, takes effect within 30 minutes and lasts for a few hours. (diabetictravelinsurance.com)
Regular insulin - It is short acting insulin and takes 1-3 hours to reach its peak activity. (findhealthtips.com)

In addition, insulin glargine has a stable metabolic profile that more closely mimics the action of endogenous insulin (Naess et al, 2004). (diabetesonthenet.com)

Commercially available systems operate in open-loop model, where the patient has to decide on administration and dose of insulin. (viamedica.pl)
A light eating is required at night with this program to prevent the hypoglycemic condition when the evening dose of insulin is active at its maximum level. (findhealthtips.com)

Glipizide is a second-generation sulfonylurea that stimulates the release of insulin from pancreatic beta cells. (medscape.com)

Metabolic activity reaches a plateau 4 hours after its administration, remaining constant for 30 hours, whereas the time-action profile of traditional Neutral Protamine Hagedorn (NPH) insulin shows a pronounced peak after 4-6 hours followed by a decline (Heinemann et al, 2000). (diabetesonthenet.com)

The only Insulin classified as a short-acting insulin. (easynotecards.com)
What is the cheapest short acting insulin? (howtotrust.com)

Proper management of DKA requires hospitalization for aggressive intravenous fluids, insulin therapy, electrolyte replacement as well as identification and treatment of the underlying precipitating event along with frequent monitoring of patient's clinical and laboratory states. (lww.com)
The most common precipitating causes for DKA include infections, new diagnosis of diabetes and nonadherence to insulin therapy. (lww.com)
The safety and performance of the InsuJet for insulin therapy is supported by a large number of clinical studies. (insujet.com)
On Friday, October 23, Dr. Matthew Riddle will chair the symposium, "Paving the Way to Patient Acceptance, Adherence and Satisfaction: The Role of Next-Generation Insulin Therapies," and Dr. Anne Peters will chair "The Evolution of Insulin Therapy: New Developments in Treatment, Technology, and Methods of Administration" on Saturday, October 24. (cardiometabolichealth.org)
Anyone who has type 1 diabetes needs lifelong insulin therapy. (diabeteshealthmatters.com)
The Diabetes Control and Complication Trial (DCCT) clearly established the benefits of intensive versus conventional insulin therapy in adolescents and adults with type 1 diabetes ( 1 ). (cdc.gov)
What is flexible insulin therapy? (carenity.us)
Who is flexible insulin therapy intended for? (carenity.us)
How does intensive insulin therapy work? (carenity.us)
People with type 1 diabetes almost always require insulin therapy and will become very sick without it. (msdmanuals.com)

The only available intermediate-acting insulin product. (easynotecards.com)

Insulin (/ˈɪn.sjʊ.lɪn/, from Latin insula, 'island') is a peptide hormone produced by beta cells of the pancreatic islets encoded in humans by the insulin (INS) gene. (wikipedia.org)
Insulin was the first peptide hormone discovered. (wikipedia.org)

Anatomy10

Organisms2

Diseases14

Chemicals and Drugs43

Analytical, Diagnostic and Therapeutic Techniques and Equipment29

Psychiatry and Psychology1

Phenomena and Processes15

Information Science3

Named Groups1

Health Care18

Geographicals2

Lispro20

Aspart8

Detemir11

Lantus11

Humalog4

Degludec3

Basaglar1

Toujeo2

Levemir2

Semglee9

Analogs9

Human insulin17

Novolog2

Types of insulin5

Glucose45

Pancreas13

Regimens13

Biosimilar5

Secretion1

Once-daily insulin glargine1

Analogues6

Doses9

Recombinant human1

Vials5

Onset2

Type of insulin4

Long-Acting Insulins1

Hypoglycemia1

Biosimilars4

Oral antidiabetic1

Pump15

Resistance8

Glycemic control1

Diabetes mellitus2

Patients19

Bolus5

Injections5

Vial3

Include insulin2

Injection13

Traditional insulins2

Humulin1

Treatment of diabetes1

Regimen3

Formulations3

Subcutaneous insulin infusion1

Pens3

Syringe5

Regular7

Endogenous1

Dose of insulin2

Release of insulin1

Neutral Protamin1

Short Acting Insulin2

Therapy10

Intermediate-acting insulin1

Hormone2