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Alzheimer DiseaseAmyloid beta-PeptidesAmyloid beta-Protein Precursortau ProteinsNeurofibrillary TanglesPlaque, AmyloidBrainApolipoprotein E4NeurofibrilsDementiaAmyloid Precursor Protein SecretasesPresenilin-1AmyloidCognition DisordersAtrophyNeuropsychological TestsDementia, VascularApolipoproteins EPeptide FragmentsMild Cognitive ImpairmentPresenilin-2HippocampusAgingNeuronsCognitionMice, TransgenicMental Status ScheduleMagnetic Resonance ImagingAspartic Acid EndopeptidasesLewy Body DiseaseAge of OnsetCholinesterase InhibitorsMemantinePresenilinsCerebral CortexAniline CompoundsBrain ChemistryMemory DisordersNational Institute on Aging (U.S.)Cerebral Amyloid AngiopathyDisease Models, AnimalAutopsyNerve DegenerationSubstantia InnominataLongitudinal StudiesProtease NexinsDown SyndromeNeurodegenerative DiseasesDisease ProgressionTauopathiesAmyloidogenic ProteinsPhenylcarbamatesPositron-Emission TomographyNerve Tissue ProteinsMolecular Sequence DataIndansThiazolesBiological MarkersGenetic Predisposition to DiseaseProdromal SymptomsNootropic AgentsLewy BodiesClioquinolGenotypeAmino Acid SequenceTacrineMutationNeuropil ThreadsTemporal LobeCase-Control StudiesFrontotemporal DementiaPhosphorylationMemoryAmnesiaReference ValuesParkinson DiseasePsychomotor AgitationGalantamineCohort StudiesAmyloidosisRisk FactorsCaregiversModels, BiologicalDementia, Multi-InfarctProtein BindingChromosomes, Human, Pair 21PC12 CellsImmunohistochemistryApolipoprotein E2MicrogliaCells, CulturedInsulysinMembrane ProteinsAstrocytesMicrotubule-Associated ProteinsAphasia, Primary ProgressiveAllelesTime FactorsGenetic TestingAge Factors