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External-beam radioth2023Computed TomographyClinicalBiopsyBiopsiesUltrasoundRecurrentAntigenTumorOutcomes2022Stereotactic radiosurgeryMultiparametricFindingsMetastasesBiochemical recurrence of prostate cancerMedical OncologyIntensity-ModulatedBrachytherapyOncologySalvage radiotherapyCastration-resistant prostate cancerArise in the peripheral zonePSMA PETProstatectomyRadiologyCentersMetastatic prostate cancerMagneticTumorsRadiation therapyMethodsPelvicBreastPrognosticTherapyDetection of prostate cancerApproachesMolecular ImagingTreatmentsChemotherapySurgeryOutcomeModalitiesConventionalPrediction2021TherapeuticsAssessmentMemorial SloanSurvivalGlandColorectal cancerOncologicalBoneDoseInterventions
External-beam radioth3
  • The investigators performed 37 radiofrequency and four microwave ablation procedures, followed within 90 days by either external-beam radiotherapy or brachytherapy in 27 and 14 patients, respectively (J Vasc Interv Radiol 2006;17[7]:1117-1124). (diagnosticimaging.com)
  • The distribution depended on the treatment received: 22.5% who received low-dose rate (LDR) brachytherapy as monotherapy, 24.0% treated with high-dose rate (HDR) boost and 32.0% treated with external-beam radiotherapy (EBRT) (P = .017). (bvsalud.org)
  • Patients with hormone-refractory prostate cancer and bone pain needing external-beam radiotherapy were assigned to four intravenous injections of (223)Ra (50 kBq/kg, 33 patients) or placebo (31 patients), given every 4 weeks. (researchgate.net)
20232
  • CAMBRIDGE, Mass. , May 26, 2023 /PRNewswire/ -- The Eureka Clinical AI platform, from ConcertAI's TeraRecon, the advanced visualization and clinical AI SaaS category leader, now provides clinicians with the state-of-the-art clinical artificial intelligence and deep learning technology necessary to bring fast and accurate prostate cancer detection and diagnosis using bpMRI and AI in partnership with Bot Image, Inc. (fox5sandiego.com)
  • Cite this: BCR Is Unreliable Surrogate for Overall Survival in Prostate Cancer - Medscape - Sep 06, 2023. (medscape.com)
Computed Tomography8
  • This study aimed to increase bladder volume reproducibility for prostate radiation therapy by implementing a bladder scanning (BS) protocol that could assist patients' bladder filling at computed tomography (CT) simulation and treatment. (nih.gov)
  • Prostate cancer staging traditionally includes computed tomography for assessment of lymph nodes and technetium-99m bone scintigraphy for assessment of bone metastases. (medscape.com)
  • However, conventional diagnostic techniques such as trans-rectal ultrasound, computed tomography (CT), magnetic resonance imaging (MRI), and bone scans show some limitations. (healthbooktimes.org)
  • Computed tomography (CT), with its inferior soft tissue contrast, compared to magnetic resonance imaging (MRI) or transrectal ultrasound (TRUS) is not considered the primary imaging method when examining the prostate. (ispub.com)
  • Computed tomography (CT) for diagnostic imaging of the prostate has been studied in the early days of this method in the late 70's and the 80's but has received little attention in the international medical literature of the last years (2-7). (ispub.com)
  • INTERVENTION: Patients underwent choline positron emission tomography/computed tomography and a bone scan, followed by prostate mpMRI and MRI-targeted and transperineal template-mapping (TTPM) biopsies. (ucl.ac.uk)
  • Researchers from the National Institutes of Health (NIH), presenting at the American Society of Clinical Oncology annual meeting, have shown that patients who undergo lung cancer screening with low-dose computed tomography (LDCT) are at high risk for receiving false-positive results. (ecancer.org)
  • 18F-fluorodeoxyglucose positron-emission tomography combined with computed tomography as a diagnostic tool in native valve endocarditis. (icr.ac.uk)
Clinical26
  • As PSMA-ligand PET/CT is increasingly adopted in clinical trials and routine practice worldwide, a unified language for image reporting is urgently needed. (snmjournals.org)
  • Radiological imaging has long been an important tool to aid in clinical decision making. (flrad.org)
  • This role is rapidly evolving from being a diagnostic tool to playing a central role in personalized medicine, most notably cancer.Radiomics is the bridge between imaging and clinical decision making. (flrad.org)
  • According to the American Society of Clinical Oncology (ASCO), one or more of the following imaging modalities should be used for patients with advanced prostate cancer: conventional imaging (CT, bone scan, and/or prostate MRI) and/or next-generation imaging (NGI) (PET, PET/CT, PET/MRI, whole-body MRI). (medscape.com)
  • It is well known that the benefits of radiotherapy are individual, so we need to find predictive markers that can be used to avoid unnecessary or ineffective radiotherapy," said Fredrik Wärnberg, professor in the clinical sciences department at Gothenburg University's Sahlgrenska Academy. (diagnosticimaging.com)
  • ConcertAI is the leading AI and RWE cancer research company, and our TeraRecon business has the leading open, trusted Clinical AI platform in the industry, available globally," said Jeff Elton , PhD, CEO of ConcertAI. (fox5sandiego.com)
  • We're very excited to add Bot Image to our partner ecosystem and to provide ProstatID™ to the Eureka Clinical AI Platform. (fox5sandiego.com)
  • Awarded the KLAS Category Leader for Advanced Visualization, TeraRecon solutions are independent of any one manufacturer's imaging equipment or PACS system, allowing a single, unified, and simplified clinical workflow that can improve efficiencies and deliver actionable physician-guided insights. (fox5sandiego.com)
  • Bot Image, Inc.'s mission is to blend artificial intelligence (AI) with other diagnostic mediums and bring about substantial improvements in clinical outcomes where it matters most: Improved cancer screening, detection, classification, and grading using non-invasive imaging technologies such as MRI and CT. (fox5sandiego.com)
  • BACKGROUND: Clinical prognostic groupings for localised prostate cancers are imprecise, with 30-50% of patients recurring after image-guided radiotherapy or radical prostatectomy. (ox.ac.uk)
  • We aimed to test combined genomic and microenvironmental indices in prostate cancer to improve risk stratification and complement clinical prognostic factors. (ox.ac.uk)
  • These properties make cancer-associated DNA methylation changes very attractive for development of cancer biomarker tests with substantive clinical utility. (frontiersin.org)
  • This review will summarize existing DNA methylation cancer biomarkers used in clinical practice across the application domains above, discuss what makes a suitable DNA methylation cancer biomarker, and identify barriers to translation. (frontiersin.org)
  • Articles regarding the diagnosis of recurrent lesions, pathology aspects due to radiotherapy effects and studies on clinical outcomes of different focal salvage approaches hold value for this issue. (frontiersin.org)
  • Construction of standardized and large databases with complex information (clinical, imaging, laboratory) will be the essential step to creating and training automated diagnostic/prognostic models that can help clinicians make unbiased and faster decisions aimed at personalized healthcare. (healthbooktimes.org)
  • Dr Yap is the Medical Director of the Institute for Applied Cancer Science, a drug discovery biopharmaceutical unit where drug discovery and clinical translation are seamlessly integrated. (biomedcentral.com)
  • He is also the Associate Director of Translational Research in the Institute for Personalized Cancer Therapy, which is an integrated research and clinical trials program aimed at implementing personalized cancer therapy and improving patient outcomes. (biomedcentral.com)
  • RayStation has very advanced tools available for taking online adaptive into clinical routine and the work done by Vejle is showcasing what groundbreakning possibilities our users have to further advance cancer treatments. (salesandmarketingnetwork.com)
  • Larger clinical trials are warranted to study (223)Ra on the prevention of SREs and on overall survival in patients with hormone-refractory prostate cancer. (researchgate.net)
  • Investigators released participant group data from a clinical trial looking at the use of fluorine 18 fluciclovine PET/CT in men with prostate cancer and biochemical recurrence to identify potential targets for therapy. (uropracticemanagement.com)
  • Surgery and locoregional radiotherapy may offer optimal clinical and radiological outcomes but have a limited role in improving local tumor control and overall survival. (iiarjournals.org)
  • Radiotherapy Standardisation and Artificial Intelligence within the National Cancer Institute's Clinical Trials Network. (cdc.gov)
  • Study protocol for a two-site clinical trial to validate a smartphone-based artificial intelligence classifier identifying cervical precancer and cancer in HPV-positive women in Cameroon. (cdc.gov)
  • And we found that in biopsy-naive men with a clinical suspicion of prostate cancer, a diagnostic pathway involving prebiopsy MRI risk stratification with MRI-targeted biopsy is superior to 10- to 12-core TRUS biopsy," he emphasized. (medscape.com)
  • While clinical care focuses on the individual health, the public health policies aimed at breast cancer focus the attention on women from various countries. (bvsalud.org)
  • In the past two decades, a multi-therapy approach has increased the rates of clinical response through neoadjuvant chemotherapy, particularly usinga nthracyclines and taxanes-based combination, surgery, radiotherapy and hormone-based therapy 5 . (bvsalud.org)
Biopsy17
  • The standard approach to the diagnosis of prostate cancer consists of prostate-specific antigen ( PSA ) screening, digital rectal examination, and random transrectal biopsy. (medscape.com)
  • Diagnosis of prostate cancer begins with PSA screening, often followed by multiparametric MRI imaging or a biomarker test to confirm suspicion (and location, if MRI) of cancer, before biopsy. (pcf.org)
  • If successful, this project will improve understanding of tumor visibility by Micro-Ultrasound, and result in a 3-minute prostate scan and urine sample test that identifies patients at risk for prostate cancer and improves decisions on whether patients should undergo prostate biopsy or not. (pcf.org)
  • Micro-Ultrasound, possibly with a urine biomarker test, to accurately determine a patient's risk for prostate cancer and aid in decisions about whether to undergo prostate biopsy. (pcf.org)
  • The ability of circulating tumor DNA liquid biopsy assays to monitor cancer in situ also allows for the ability to monitor response to therapy, to detect minimal residual disease and as an early biomarker for cancer recurrence. (frontiersin.org)
  • Arguments against primary focal therapy focus on the multifocality of prostate cancer and the inability of current imaging and biopsy modalities to accurately stage all clinically significant cancer foci. (frontiersin.org)
  • Four cancer (6%) were missed by TTPM biopsy and six (8%) were missed by MRI-targeted biopsy. (ucl.ac.uk)
  • Which brings me to today (11/16/12), I had the prostate biopsy. (cancer.org)
  • Numerous single-center and meta-analysis studies have found that overall prostate cancer (PCa) detection rates using biparametric magnetic resonance imaging (bpMRI) are equivalent to those of multiparameter MRI (mpMRI), with a comparable efficacy in guiding targeted biopsy ( 1 - 5 ). (iiarjournals.org)
  • After MRI, you can today proceed with targeted tissue samples using fusion biopsy equipment, where images from the MRI examination are combined with ultrasound. (lu.se)
  • NCCN panel members were divided on the question of PSA thresholds that would prompt prostate biopsy: options include 2.5 ng/mL, 3 ng/mL, or considering the PSA level in the context of other risk factors rather than using a specific PSA cutoff. (medscape.com)
  • The results show that multiparametric MRI followed by targeted biopsy performed only on patients whose scans were positive detected more clinically significant prostate cancer and less clinically insignificant prostate cancer than the standard approach of 10- to 12-core transrectal ultrasonography-guided biopsy (TRUS), and it did so with fewer biopsy cores. (medscape.com)
  • In men who need to have investigation for prostate cancer for the first time, PRECISION shows that using an MRI to identify suspected cancer in the prostate and performing a prostate biopsy targeted to the MRI information leads to more cancers being diagnosed than the standard way that we have been performing prostate biopsy for the last 25 years," he added in a statement. (medscape.com)
  • The PRECISION trial involved 500 men who had not previously undergone a biopsy of the prostate. (medscape.com)
  • Clinically significant cancer was detected in 38% of the MRI-targeted biopsy group compared with 26% of the TRUS group, a difference between the groups that was significant ( P = .005). (medscape.com)
  • Active surveillance includes periodic PSA testing, digital rectal examination (DRE), and prostate biopsy. (medscape.com)
  • IBC may be diagnosed by an imaging test and by a breast biopsy of an invasive cancer 7 . (bvsalud.org)
Biopsies12
  • Imaging plays an important role in the noninvasive detection, localization, grading, and staging of prostate carcinoma and in carrying out biopsies for histopathologic analysis of the tumor. (medscape.com)
  • Current prostate cancer screening methods either lack specificity (PSA tests) or are costly and not widely available (MRI), thus many more patients undergo invasive prostate biopsies than are necessary. (pcf.org)
  • Bot Image's prostate AI software, ProstatID™, aims to increase the accuracy in PCa detection and diagnosis and has been shown to increase prostate cancer detection while decreasing false positives that may lead to expensive and unwarranted biopsies. (fox5sandiego.com)
  • We applied unsupervised and supervised machine learning techniques to the copy-number profiles of 126 pre-image-guided radiotherapy diagnostic biopsies to develop prognostic signatures. (ox.ac.uk)
  • The first step is multiple-needle biopsies that take samples from their prostate (which entails risk of infection). (healthydebate.ca)
  • Is the diagnostic yield of prostate needle biopsies affected by prostate volume? (urotoday.com)
  • Magnetic Resonance Imaging and targeted biopsies compared to transperineal mapping biopsies prior to salvage focal therapy/ablation in localised and metastatic recurrent prostate cancer after radiotherapy. (ucl.ac.uk)
  • DESIGN, SETTING, AND PARTICIPANTS: The FORECAST trial was both a paired-cohort diagnostic study evaluating prostate multiparametric MRI (mpMRI) and MRI-targeted biopsies in the detection of recurrent cancer and a cohort study evaluating focal ablation at six UK centres. (ucl.ac.uk)
  • OUTCOME MEASUREMENTS AND STATISTICAL ANALYSIS: Primary outcomes were the sensitivity of MRI and MRI-targeted biopsies for cancer detection, and urinary incontinence after focal ablation. (ucl.ac.uk)
  • CONCLUSIONS: Patients should undergo prostate MRI with both systematic and targeted biopsies to optimise cancer detection. (ucl.ac.uk)
  • PATIENT SUMMARY: We investigated the role of magnetic resonance imaging (MRI) scans of the prostate and MRI-targeted biopsies in outcomes after cancer-targeted high-intensity ultrasound or cryotherapy in patients with recurrent cancer after radiotherapy. (ucl.ac.uk)
  • Our findings show that these patients should undergo prostate MRI with both systematic and targeted biopsies and then ablative treatment focused on areas of recurrent cancer to preserve their quality of life. (ucl.ac.uk)
Ultrasound13
  • Micro-Ultrasound is a high-resolution transrectal ultrasound method that may offer a promising alternative prostate cancer diagnostic, as it retains similar cancer visualization sensitivity as MRI, at 6% of the cost. (pcf.org)
  • However, dense benign tissue appears cancerous on Micro-Ultrasound, resulting in low cancer specificity. (pcf.org)
  • Wayne Brisbane is investigating methods to improve Micro-Ultrasound specificity and evaluate Micro-Ultrasound versus MRI for prostate cancer visualization. (pcf.org)
  • This model will use data including age, PSA, DRE findings, prostate volume, and whole gland Micro-Ultrasound images to risk stratify patients following PSA screening. (pcf.org)
  • The team will also compare the specificity and sensitivity of Micro-Ultrasound versus MRI and evaluate if a urine-based biomarker test can further improve specificity for cancer diagnosis. (pcf.org)
  • The team will compare the biological differences in what these imaging methods detect, the molecular characteristics of tumors visible on MRI and Micro-Ultrasound vs. tumors visible by only one modality. (pcf.org)
  • Differing from traditional imaging techniques, CEUS employs ultrasound contrast agents. (axisimagingnews.com)
  • MONTREAL, April 30 /PRNewswire/ -- Resonant Medical, an innovator in 3D ultrasound image-guided adaptive radiotherapy products, today announced the appointment of Stephen Whisenhunt to the position of Vice President of Global Sales and Marketing. (biospace.com)
  • Resonant Medical (Montreal, Canada) develops, manufactures and commercializes 3D ultrasound image-guided adaptive radiotherapy products. (biospace.com)
  • Image-guided intervention and advanced ultrasound imaging to develop ultrasound-guided solutions for a variety of medical conditions. (hopkinsmedicine.org)
  • So patients with suspect findings on digital rectal examination or ultrasound may have the need for further CT imaging. (ispub.com)
  • Especially in imaging of the prostate it is beside transrectal ultrasound (TRUS) the examination of choice (1). (ispub.com)
  • 3-D Microvascular Imaging Using High Frame Rate Ultrasound and ASAP Without Contrast Agents: Development and Initial In Vivo Evaluation on Nontumor and Tumor Models. (icr.ac.uk)
Recurrent7
  • For patients with locally recurrent prostate cancer after primary radiotherapy, focal salvage treatment is potentially even more attractive compared to the primary setting due to the more often unifocal nature of the recurrent cancer. (frontiersin.org)
  • Salvage radiotherapy decisions for patients with recurrent prostate cancer after prostatectomy change after 18 F-fluciclovine PET/CT reveals higher positive findings than conventional imaging. (uropracticemanagement.com)
  • BACKGROUND: Recurrent prostate cancer after radiotherapy occurs in one in five patients. (ucl.ac.uk)
  • The efficacy of prostate magnetic resonance imaging (MRI) in recurrent cancer has not been established. (ucl.ac.uk)
  • OBJECTIVE: To evaluate the role of prostate MRI in detection of prostate cancer recurring after radiotherapy and the role of salvage focal ablation in treating recurrent disease. (ucl.ac.uk)
  • Imaging with 68 Ga-PSMA-11 PET led to major management changes in patients with biochemically recurrent prostate cancer, according to findings from a prospective, single-arm trial presented during the 2020 European Association of Urology Virtual Congress. (urologytimes.com)
  • A population-based study on the management and outcome in patients with locally recurrent rectal cancer. (cancercentrum.se)
Antigen9
Tumor7
  • [ 15 ] Furthermore, different treatment options, ranging from early aggressive treatments, such as radical prostatectomy and radical radiotherapy, to deferred treatments (ie, treating men if and when the disease progresses and becomes symptomatic), are dependent on parameters such as tumor grade and tumor stage. (medscape.com)
  • Instead of focusing on markers within the tumor cells, the team pivoted to examine the role cells surrounding the tumor might play in the efficacy of radiotherapy. (diagnosticimaging.com)
  • Resonant's technology provides a solution for a clearly unmet need in breast cancer treatment--addressing the issue of tumor movement for breast and prostate cancer patients in a way that has never been done before," said Whisenhunt. (biospace.com)
  • AI may improve PC's patient care in many different fields, from the semi-automatization of tumor segmentation, through the technical aspect of image preparation, interpretation, the calculation of additional factors based on data obtained during scanning, to prognostic prediction and risk-group selection. (healthbooktimes.org)
  • Genome instability is a hallmark of cancer, and gives tumor cells many selective advantages, accelerating the evolutionary processes which allow cancers to thrive. (biomedcentral.com)
  • The impact of local tumor ablative therapy in oligometastasized prostate cancer (PC) is still under debate. (biomedcentral.com)
  • After radiotherapy (RT), recurrence can occur at the primary tumor site or at a different site and can be detected as a focal high signal on DWI at high b-values, or focal moderate or marked low signal on apparent diffusion coefficient (ADC) maps. (iiarjournals.org)
Outcomes7
  • To do so, researchers analyzed a large tissue collection from a randomized radiotherapy study (SweDCIS), and they found that women who have low PDGFRb levels have better outcomes with radiotherapy for ipsilateral breast events (IBE). (diagnosticimaging.com)
  • September 26, 2017 - Psychological distress has long been associated with negative health outcomes for cancer patients, though specific reasons remain unclear. (itnonline.com)
  • Our study demonstrates an association between distress and radiation therapy-specific outcomes, adding to the growing body of evidence emphasizing a need for an interdisciplinary approach to cancer care," said Anderson. (itnonline.com)
  • The imaging outcomes also lead to a decline from 68% to 29% in the proportion of patients with unknown sites of disease. (urologytimes.com)
  • The primary outcome was the proportion of men with clinically significant cancer, defined as a Gleason 3+4 or greater," Kasivisvanathan observed, "while important secondary outcomes included the proportion of men with clinically insignificant cancer, Gleason grade 3+3. (medscape.com)
  • The evolving culture of cancer care, puting to radiotherapy planning (e.g. nologies undeniably contribute to and cancer medicine more broadly, deep learning to facilitate automated better outcomes for cancer patients has also played a major part in these treatment contouring and planning). (who.int)
  • Impact of a surgical training programme on rectal cancer outcomes in Stockholm. (cancercentrum.se)
20221
Stereotactic radiosurgery1
  • As part of Hendrick Health's commitment to innovative cancer care for the region, a second linear accelerator is now in operation at Hendrick Cancer Center in Abilene to provide stereotactic radiosurgery and precision radiotherapy when radiation therapy is needed. (hendrickhealth.org)
Multiparametric4
  • Uniform frameworks for image reporting have previously been proposed for pelvic multiparametric MRI ( 17 ), bone scintigraphy ( 18 ), and many other techniques and indications ( 19 , 20 ). (snmjournals.org)
  • Multiparametric magnetic resonance imaging (mpMRI) has been increasingly used. (medscape.com)
  • Advances in diagnostic imaging such as PSMA-PET CT in combination with multiparametric MRI and pathology are also of interest. (frontiersin.org)
  • While the predictive value of multiparametric (mp)MRI in prostate cancer (pCa) treatment is well-known, the potential of imaging features extracted from CBCT is novel for patients with pCa. (aapm.org)
Findings8
  • Researchers noted a 20.1 percent incidence of bone-only metastasis in a cohort of men with castration-resistant prostate cancer, according to findings from research presented at the recent Society for Nuclear Medicine and Molecular Imaging (SNMMI) conference. (diagnosticimaging.com)
  • Additionally, flowcharts integrating findings of PSMA-ligand PET and morphologic imaging have been designed to guide image interpretation. (snmjournals.org)
  • We investigated the findings on pre-treatment MRI and its potential influence on treatment decisions, and its ability to predict biochemical recurrence in patients treated with radiotherapy. (bvsalud.org)
  • According to recent findings reported in the NEJM 1 , waiting and watching (i.e., surveillance of the cancer) can be more appropriate than intervention, thus saving healthcare dollars and undesirable side effects of treatments. (fox5sandiego.com)
  • In this review an overview of the normal anatomy and common imaging findings in prostatic diseases is given. (ispub.com)
  • False-positive results were defined as noncalcified nodules greater than or equal to 4 mm or other findings that indicated a suspicion of cancer that were later found to be noncancerous. (ecancer.org)
  • Despite methodological differences, findings evidence that although IBC presents particular features (lower survival rate and worse prognostics than most types of breast cancer), very few studies examine its epidemiology and specific risk factors in depth and use any other therapeutic approaches than those commonly used for other breast cancer subtypes. (bvsalud.org)
  • Radiological findings do not support lateral residual tumour as a major cause of local recurrence of rectal cancer. (cancercentrum.se)
Metastases6
  • Quantitative imaging and image quality optimization to assess therapeutic response in prostate cancer patients with skeletal metastases. (hopkinsmedicine.org)
  • To gain data for this approach, we evaluated oligometastasized PC patients receiving stereotactic body radiotherapy (SBRT) to bone metastases. (biomedcentral.com)
  • The local treatment of liver metastases in oligometastatic colorectal cancer, for instance, leads to a significant life-prolongation, as does the local treatment of sarcoma metastases deriving from different localizations [ 9 ]. (biomedcentral.com)
  • The alpha-emitter radium-223 ((223)Ra) is a bone-seeking radionuclide studied as a new treatment for patients with bone metastases from hormone-refractory prostate cancer. (researchgate.net)
  • patients with bone metastases from hormone-refractory prostate cancer. (researchgate.net)
  • The potential for improved outcome in patients with hepatic metastases from colon cancer: A population-based study. (cancercentrum.se)
Biochemical recurrence of prostate cancer2
  • Tumour genomic and microenvironmental heterogeneity for integrated prediction of 5-year biochemical recurrence of prostate cancer: a retrospective cohort study. (ox.ac.uk)
  • Recently released analysis of 18 F-DCFPyL PET/CT accuracy demonstrated improved diagnostic capability in men with biochemical recurrence of prostate cancer. (uropracticemanagement.com)
Medical Oncology1
  • He is an Associate Professor in the Department for Investigational Cancer Therapeutics (Phase I Program), and the Department of Thoracic/Head and Neck Medical Oncology. (biomedcentral.com)
Intensity-Modulated2
  • Evidence of variations in bladder filling effecting prostate stability and therefore treatment and side-effects is well established with intensity modulated radiation therapy (IMRT). (nih.gov)
  • Furthermore, it allows for precise treatment of cancers, while limiting radiation dose to other organs and tissues by means of Cone-beam CT based imaging and repositioning, Multi-leaf collimation (MLC blocking) systems, and Intensity modulated radiation therapy (IMRT). (lmmedicalcenter.com)
Brachytherapy1
Oncology6
  • 1 Department of Radiation Oncology North Coast Cancer Institute Coffs Harbour Health Campus Coffs Harbour New South Wales Australia. (nih.gov)
  • Radiation Oncology Systems is a comprehensive provider of radiation therapy and diagnostic imaging equipment and services. (biospace.com)
  • Our physicians and nursing teams are nationally recognized for their expertise and apply the latest advances in cancer care to screening and prevention, diagnosis, medical, radiation and surgical oncology treatment, and rehabilitation. (massgeneral.org)
  • Our medical oncologists have extensive experience treating cancer and work closely with patients and their care teams, including specialists in surgical and radiation oncology, to plan the best combination and timing of medical therapies. (massgeneral.org)
  • Radiation oncology services at the Mass General/North Shore Cancer Center combine the latest technology with a team of professionals who are specially trained in the planning and delivery of radiation therapy. (massgeneral.org)
  • The study received support from Cancer Research UK, the UK National Health Service, the Prostate Cancer National Institutes of Health Specialized Programs of Research Excellence, the UK Department of Defense, the Prostate Cancer Foundation, and the American Society for Radiation Oncology. (medscape.com)
Salvage radiotherapy1
  • In cases in which salvage radiotherapy is being considered, NGI should be offered (PSMA imaging, 11 C choline or 18 F fluciclovine PET/CT or PET/MRI, whole-body MRI, and/or 18 F sodium fluoride [NaF] PET/CT) because they have been shown to have superior disease detection performance characteristics and may alter patient management. (medscape.com)
Castration-resistant prostate cancer1
  • There is a need for improved therapeutic approaches for patients with advanced metastatic castration-resistant prostate cancer (mCRPC), whilst on the other extreme, there is a need to accurately identify clinically significant prostate cancer in individuals presenting with elevated PSA levels or inconclusive MRI results. (pcf.org)
Arise in the peripheral zone2
  • Seventy percent of prostate cancers arise in the peripheral zone, 15-20% in the central zone, and 10-15% in the transition zone. (medscape.com)
  • The zonal anatomy is of importance as most cancers arise in the peripheral zone. (ispub.com)
PSMA PET2
  • Maximum intensity projections (MIP) of different PET tracers for prostate cancer: A) [ 18 F]PSMA PET of a patient with mCRPC with multiple lymph nodes and bone metastasis. (healthbooktimes.org)
  • Gallium-68 PSMA PET/CT imaging in patients with early relapsed prostate cancer confirms the reliability of this imaging modality in local and metastatic lesion detection. (uropracticemanagement.com)
Prostatectomy6
Radiology8
  • In the third episode of a three-part podcast, Anand Narayan, M.D., Ph.D., and Amy Patel, M.D., discuss the challenges of expanded breast cancer screening amid a backdrop of radiologist shortages and ever-increasing volume on radiology worklists. (diagnosticimaging.com)
  • 10 Diagnostic Imaging and Interventional Radiology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida. (aacrjournals.org)
  • 16 Mallinckrodt Institute of Radiology and Alvin J. Siteman Cancer Center, Washington University School of Medicine, St. Louis, Missouri. (aacrjournals.org)
  • The ability to consider and comment on prior imaging in the radiology report may help reduce extraneous addenda requests. (diagnosticimaging.com)
  • Establish a graduate degree program in medical imaging physics within the Department of Radiology and Radiological Science. (hopkinsmedicine.org)
  • This section of Diagnostics aims to enable the rapid publication of contributions in the fields of radiology, nuclear medicine, and medical imaging. (mdpi.com)
  • Our department provides individually tailored medical care that not only diagnoses and treats respiratory disease, but also supports patients' rehabilitation to diagnose and treat lung cancer, we hold joint conferences with the Department of General Thoracic Surgery, Department of Radiology, and Department of Diagnostic Pathology. (keio.ac.jp)
  • We provide medical care in cross-sectional cooperation with other facilities, such as the Department of General and Gastroenterological Surgery, Department of Radiology, Cancer Center, Center for Diagnostic and Therapeutic Endoscopy, and Immunotherapy Center. (keio.ac.jp)
Centers1
  • Originally developed at McGill University Health Center, Resonant's technologies are available in more than 50 cancer centers in the U.S., Canada and Europe, helping cancer centers make significant improvements in radiation therapy planning, verification and delivery -- advancing patient care. (biospace.com)
Metastatic prostate cancer2
Magnetic3
  • Because of the superior soft tissue contrast magnetic resonance imaging (MRI) is the preferred imaging evaluation of the pelvis. (ispub.com)
  • The application of biparametric magnetic resonance imaging (bpMRI) [T2-weighted (T2W) and diffusion weighted imaging (DWI)/apparent diffusion coefficient (ADC)] using dedicated structured methods, such as Simplified Prostate Imaging Reporting and Data System (S-PI-RADS) for the detection, categorization, and management of prostate cancer (PCa) is reported. (iiarjournals.org)
  • If the PSA level is a little too high, the patient should first get a magnetic resonance imaging (MRI) examination", says Anders Bjartell, Professor and Senior Consultant in Urology at Lund University and Skåne University Hospital. (lu.se)
Tumors2
  • Dr. Damian Dupuy, an interventional radiologist at Brown, and colleagues enrolled 41 patients with inoperable stage I/II non-small cell lung cancer tumors who underwent thermal ablation and radiotherapy between 1998 and 2005. (diagnosticimaging.com)
  • The system can be used to treat tumors of the brain, spine, lung, esophagus, prostate and other areas that are typically difficult to treat surgically. (hendrickhealth.org)
Radiation therapy3
  • Stereotactic radiation therapy is specially used to diagnosis and treat wide range of cancers. (pharmiweb.com)
  • A new study finds that roughly half of all patients who reported having severe distress, which the National Comprehensive Cancer Network (NCCN) describes as "a mix of anxiety and depressive symptoms," subsequently missed one or more radiation therapy appointments and/or were admitted to the hospital during their treatment, compared with fewer than 20 percent of patients who reported lower levels of distress. (itnonline.com)
  • We apply this framework to breast cancer treatments, where lumpectomy with radiation therapy is more expensive than mastectomy but generates similar average health benefits. (cdc.gov)
Methods2
  • METHODS: We used DNA-based indices alone or in combination with intra-prostatic hypoxia measurements to develop four prognostic indices in 126 low-risk to intermediate-risk patients (Toronto cohort) who will receive image-guided radiotherapy. (ox.ac.uk)
  • Iterative image reconstruction methods and task-based image quality evaluation for x-ray CT. (hopkinsmedicine.org)
Pelvic2
  • The prostate is depicted in abdominal/ pelvic CT examinations and pathology of the prostate should not be missed. (ispub.com)
  • The prostate is depicted in abdominal/ pelvic CT examinations being performed for wide range of indications, for example cancer staging, acute abdomen or fractures. (ispub.com)
Breast13
  • Women who have lower levels of a fibroblast protein that is integral to the development of the cardiovascular system - PDGFRb - have a better response to radiotherapy treatment for early-stage breast cancer. (diagnosticimaging.com)
  • Develop and evaluate agents for alpha-RPT to treat a variety of cancers (breast, liver/liver mets, melanoma). (hopkinsmedicine.org)
  • Do 'forever chemicals' increase breast cancer risk? (ecancer.org)
  • Background Two-thirds of patients with early breast cancer undergo breast-conserving treatment (BCT). (icr.ac.uk)
  • 5-fraction radiotherapy for breast cancer: FAST Forward to implementation. (icr.ac.uk)
  • People with the gene may be at increased risk for breast or ovarian cancer. (medlineplus.gov)
  • Inflammatory Breast Cancer (IBC) is a rare and very aggressive type of cancer that tends to develop at a younger age, compared with other subtypes of breast cancer. (bvsalud.org)
  • Breast cancer is a public health problem, its incidence increases worldwide. (bvsalud.org)
  • Breast cancer brings number of impacts for women. (bvsalud.org)
  • Inflammatory Breast Cancer (IBC) is a rare, although highly aggressive and lethal 3 type of cancer. (bvsalud.org)
  • With an average survival rate of three years, IBC accounts for about 2.5% of all breast cancer types in the US. (bvsalud.org)
  • IBC tends to develop at a younger age than the more common form of breast cancer 5 . (bvsalud.org)
  • The fact that it is a rare form of breast cancer and rarely causes a breast lump, it is harder to diagnose at early stage. (bvsalud.org)
Prognostic5
  • however, little is known about its potential for radiotherapy treatment decision, or its prognostic value. (bvsalud.org)
  • Promising diagnostic and prognostic information with PSMA-based radioligands discussed in recently released review article. (uropracticemanagement.com)
  • this has created an expo- precision surgery, including the intel- to send money to family members nentially increasing number of types ligent scalpel (which provides instan- to pay for treatment or by doctors of cancers, as well as pathways of taneous diagnosis during surgery), to evaluate images and patholo- care, defined by prognostic stratifi- nanorobotics (Felfoul et al. (who.int)
  • The surgeon as a prognostic factor after the introduction of total mesorectal excision in the treatment of rectal cancer. (cancercentrum.se)
  • Prognostic significance of both surgical and pathological assessment of curative resection for rectal cancer. (cancercentrum.se)
Therapy4
  • Focal therapy (FT) has been suggested as a treatment which, in a subgroup of patients, could lead to durable cancer control while reducing side-effects. (frontiersin.org)
  • Arguments against focal therapy are the primary multifocality often observed in prostate cancer and potential understaging of clinically significant disease. (frontiersin.org)
  • It was rebranded as the Radiological Physics Division to expand its mission beyond imaging so that all of radiological physics, including radionuclide therapy is encompassed. (hopkinsmedicine.org)
  • Because of the complexity of these motions, Verity Radiation uses special high-speed computers, treatment-planning software, diagnostic imaging and patient-positioning devices to plan treatments and control the radiation dose during therapy. (lmmedicalcenter.com)
Detection of prostate cancer1
Approaches4
  • While the tailoring of treatment to patients dates back at least to the time of Hippocrates, the term has risen in usage in recent years given the growth of new diagnostic and informatics approaches that provide understanding of the molecular basis of disease, particularly genomics. (wikipedia.org)
  • Combination approaches, including chemotherapies, radiotherapies and immunotherapies. (biomedcentral.com)
  • Some trials were conducted over 20 years ago, and a variety of factors, including patient selection, staging, diagnostic criteria, and therapeutic approaches, have evolved in that time. (medscape.com)
  • COPENHAGEN, Denmark - The standard of care for diagnosing prostate cancer is set to change because of results now published from a head-to-head comparison of two different approaches. (medscape.com)
Molecular Imaging4
  • We propose a molecular imaging TNM system (miTNM, version 1.0) as a standardized reporting framework for PSMA-ligand PET/CT or PET/MRI. (snmjournals.org)
  • The Prostate Cancer Molecular Imaging Standardized Evaluation (PROMISE) criteria reported in this issue of The Journal of Nuclear Medicine summarize standards for study design and reporting of prostate cancer molecular imaging. (snmjournals.org)
  • The aim of this review is to describe the current literature on AI applied to molecular imaging for prostate cancer (PC). (healthbooktimes.org)
  • The implementation of AI algorithms in PC molecular imaging can improve and ease the diagnostic, predictive process, and global patient care. (healthbooktimes.org)
Treatments3
  • Our team of radiation oncologists offers a variety of radiation treatments to treat cancer. (massgeneral.org)
  • Our Oncologists determine how often you'll receive chemotherapy treatments based on what drugs you'll receive, the characteristics of your cancer and how well your body recovers after each treatment. (lmmedicalcenter.com)
  • Our field has made great advancements in treatments for patients with cancer, but psychosocial factors influence a patient's ability to receive the appropriate treatment without delay or interruption. (itnonline.com)
Chemotherapy3
  • These include close observation with repeat testing to see if the disease is progressing, major surgery, radiotherapy by implants or external beam, and chemotherapy of various types. (healthydebate.ca)
  • Each person with cancer reacts differently to chemotherapy and its various side effects. (lmmedicalcenter.com)
  • Adjuvant radiotherapy (83.7%) and/or chemotherapy (10.6%) were often administered. (iiarjournals.org)
Surgery9
  • For ductal carcinoma in situ (DCIS), the current treatment is surgery and subsequent radiotherapy. (diagnosticimaging.com)
  • But it appears that within a few years of being diagnosed with low-risk prostate cancer, many men or their physicians become anxious about regular repeat testing and opt for surgery . (healthydebate.ca)
  • Bone marrow transplantation, including haploid transplantation from a semi-compatible donor (when it is not possible to find a fully compatible donor) Our clinics have already updated the equipment in the radiotherapy and radiosurgery departments for the treatment of various oncological diseases without surgery. (intergeomed.com)
  • In the LDCT group, 6.6 per cent of patients with false positives underwent invasive diagnostic procedures and 1.6 per cent had major surgery. (ecancer.org)
  • Registration and validity of surgical complications in colorectal cancer surgery. (cancercentrum.se)
  • The circular stapling device as a risk factor for anastomotic leakage in rectal cancer surgery. (cancercentrum.se)
  • Elective surgery for colorectal cancer in a defined population. (cancercentrum.se)
  • Local surgery for rectal cancer - A population based study. (cancercentrum.se)
  • Risk factors for anastomotic leakage after rectal cancer surgery: a case-control study. (cancercentrum.se)
Outcome3
  • INTERPRETATION: This is the first study of cancer outcome to integrate DNA-based and microenvironment-based failure indices to predict patient outcome. (ox.ac.uk)
  • Effect of a surgical training programme on outcome of rectal cancer in the County of Stockholm. (cancercentrum.se)
  • Colon cancer management and outcome in relation to individual hospitals in a defined population. (cancercentrum.se)
Modalities3
  • Focal salvage with differing modalities seems to reduce these toxicity risks, while maintaining cancer control in a substantial group of patients. (frontiersin.org)
  • Since leaps in AI-based image recognition technology opened the market gates, over 60 entities including 40 new firms globally have set out to commercialize AI-based medical diagnostics based on various imaging modalities. (idtechex.com)
  • The Spearman correlation (R) was used to investigate the associations between the radiomics features of the aforementioned imaging modalities. (aapm.org)
Conventional1
  • The accuracy of PSMA-ligand hybrid imaging is superior to that of conventional imaging and tracers such as choline across a range of indications and disease extents ( 2 - 15 ). (snmjournals.org)
Prediction1
  • Prediction of locations in medical images using orthogonal neural networks. (cdc.gov)
20211
Therapeutics1
  • Considering this intrinsic relationship, targeting cancer genomic instability with therapeutics has potential to improve the lives of cancer patients. (biomedcentral.com)
Assessment4
  • However, it has limitations in the assessment of certain tumours, above all (but not only) prostate cancer. (iaea.org)
  • Prostate Imaging Reporting & Data System (PI-RADS) score, index lesion diameter and the presence of organ confined disease or extra-prostatic extension were correlated with their Cancer of the Prostate Risk Assessment (CAPRA) score. (bvsalud.org)
  • AI-based image reconstruction, quality assessment, response evaluation. (hopkinsmedicine.org)
  • Segelman J, Singnomklao T, Hellborg H, Martling A. Differences in MDT assessment and treatment between patients with stage IV colon and rectal cancer. (cancercentrum.se)
Memorial Sloan1
  • 1 Memorial Sloan Kettering Cancer Center, New York, New York. (aacrjournals.org)
Survival10
  • Patients with inoperable lung cancer treated with a combination of thermal ablation and radiotherapy were able to add two years to their survival times, according to Brown University Medical School researchers. (diagnosticimaging.com)
  • We identified four genomic subtypes for prostate cancer, which had different 5-year biochemical relapse-free survival. (ox.ac.uk)
  • The recent release of EMPIRE-1 phase 2/3 trial results indicates the use of fluorine 18 fluciclovine PET/CT to guide salvage postprostatectomy radiotherapy increases event-free survival from biochemical recurrence or persistence. (uropracticemanagement.com)
  • Biochemical recurrence (BCR) falls short as a reliable surrogate for overall survival in localized prostate cancer trials and may not be a suitable primary endpoint. (medscape.com)
  • In trials of localized prostate cancer, BCR remains a controversial surrogate endpoint for overall survival. (medscape.com)
  • Trends in cancer incidence, mortality, and patient survival in the United States, as well as many other studies, are derived from this data bank. (cdc.gov)
  • It aims to improve quality of life and survival for adults with colorectal cancer through management of local disease and secondary tumours (metastatic disease). (bvsalud.org)
  • Improved survival in cancer of the colon and rectum in Sweden. (cancercentrum.se)
  • Cancer staging and survival in colon cancer is dependent on the quality of the pathologists' specimen examination. (cancercentrum.se)
  • Rectal cancer survival in the Nordic countries and Scotland. (cancercentrum.se)
Gland2
  • The normal prostate gland has a chestnut appearance. (ispub.com)
  • With imaging two of these can be depicted, a smaller central and a larger peripheral zone containing up to 70% of the gland volume. (ispub.com)
Colorectal cancer1
  • Real-time automated diagnosis of colorectal cancer invasion depth using a deep learning model with multimodal data (with video). (cdc.gov)
Oncological1
  • This Atlas will allow professionals interested in non-FDG PET/CT imaging to embrace the variety of oncological imaging by providing clinically relevant teaching files on the effectiveness and diagnostic quality of non-FDG-PET/CT imaging in routine applications. (iaea.org)
Bone3
  • SBRT offers high local cancer control rates in bone oligometastases of PC and should be evaluated with the aim of curation or to delay modification of systemic treatment. (biomedcentral.com)
  • Bone-targeting properties of (223)Ra could also potentially be used for treating skeletal metastasis from other primary cancers. (researchgate.net)
  • Recently released study results indicate whole-body MRI is superior to bone scan for prognosis in patients with metastatic hormone-naïve prostate cancer. (uropracticemanagement.com)
Dose3
  • Based on a retrospective review of 524 prostate cancer patients, a bladder volume of 250-350 mL was adopted as 'ideal' for achieving planning dose constraints. (nih.gov)
  • Twenty patients receiving radiotherapy for pCa who were treated on a variety of dose fractionations as part of IRB-approved protocols were included. (aapm.org)
  • The new radiosurgery system has sophisticated architecture that synchronizes imaging, patient positioning, motion management, beam shaping and dose delivery. (hendrickhealth.org)
Interventions1
  • iMPI technology represents a significant advancement in the field of medical imaging that may potentially revolutionize the way endovascular interventions are conducted. (diagnosticimaging.com)