Radiotherapy for breast cancer. Medical search. Frequent questions

The EBCTCG investigators wrote in the background that studies have shown that, following breast-conserving surgery or following mastectomy for node-positive disease, postoperative radiotherapy can reduce breast cancer mortality. (esmo.org)
2. Resection of the primary tumor should be the base of the surrounding normal breast, especially in and around (up, down, left, right, front and back) put silver clip (anti-magnetic material), for the accuracy of postoperative radiotherapy reduced fields positioning reference. (cancerlive.net)
We have identified a subgroup of older patients at sufficiently low risk of recurrence for whom omission of postoperative radiotherapy after breast-conserving surgery and adjuvant endocrine therapy is a reasonable option," said Ian Kunkler, FRCR, of the Edinburgh Cancer Research Center in the University of Edinburgh in Edinburgh, Scotland. (cancertherapyadvisor.com)
Although more than 50% of patients with early breast cancer present at the age of 65 years or older, evidence of the role of postoperative radiotherapy after breast-conserving surgery is sparse, he said. (cancertherapyadvisor.com)
Between April 2003 and December 2009, the PRIME II-Postoperative Radiotherapy in Minimum-Risk Elderly-study randomly assigned 1,326 patients either to receive radiotherapy (n = 658) or not receive radiotherapy (n = 668). (cancertherapyadvisor.com)
These results "are likely to lead to the consideration of omission of postoperative radiotherapy in patients meeting the eligibility criteria for the trial," Dr. Kunkler concluded, adding they certainly warrant a discussion between physician and patient whether the modest benefit shown with radiotherapy is worth the risk. (cancertherapyadvisor.com)
The researchers carried out a descriptive study using bibliometric and scientometric methods and found that the combination of surgery with postoperative radiotherapy is effective and more efficient than these alone for the treatment of patients affected by metastatic neurological compression. (bvsalud.org)
Decompression surgery and postoperative radiotherapy was mostly palliative. (bvsalud.org)

The subtype of breast cancer that researchers focused on - luminal A - represents up to 60 per cent of all breast cancers diagnosed annually and is associated with a lower risk of recurrence. (news-medical.net)
When planning the study, the investigators predicted that the risk of developing recurrence in the breast would be very low at five years. (news-medical.net)
At five years post-surgery, researchers found the recurrence of cancer in the breast was only 2.3 per cent without radiotherapy. (news-medical.net)
The overall risk of cancer recurrence following breast-conserving surgery has decreased in recent years because of regular mammogram screening, improved surgical techniques and better systemic treatments, the authors say. (news-medical.net)
The main aim of an individual patient data meta-analysis of 14324 women included in 16 studies was to assess the effects of regional node radiotherapy on breast cancer recurrence and mortality, reporting separate meta-analyses of the newer and older trials. (esmo.org)
Regional node radiotherapy in the early trials, which started during the 1960s and 1970s, had little effect on overall recurrence or breast cancer mortality and increased non-breast-cancer mortality, leading to a net increase in overall mortality. (esmo.org)
In contrast, regional node radiotherapy in the newer trials, which would have been delivered in the 1990s and 2000s, significantly reduced breast cancer recurrence and mortality, with no apparent increase in non-breast-cancer mortality, resulting in significantly reduced overall mortality. (esmo.org)
Primary outcomes were recurrence at any site, breast cancer mortality, non-breast-cancer mortality, and all-cause mortality. (esmo.org)
This absolute risk can be weighed against the probable absolute reduction in her risk of recurrence or death from breast cancer that would be achieved with radiotherapy. (cardiobrief.org)
The evidence produced by these three well-conducted trials suggests that recurrence of a woman's cancer and her chances of dying from breast cancer are similar regardless of the order of the treatments, provided that both radiotherapy and chemotherapy are commenced within seven months of the surgery. (cochrane.org)
The data included in this review, from three well-conducted randomised trials, suggest that different methods of sequencing CT and RT do not appear to have a major effect on recurrence or survival for women with breast cancer if RT is commenced within seven months after surgery. (cochrane.org)
The trial showed no difference in terms of breast cancer-related mortality or disease recurrence between a higher dose and longer intensity of radiotherapy treatment and a lower dose shorter intensity of radiotherapy treatment. (hospitalhealthcare.com)
Patients receiving chemotherapy without first 6 weeks after starting radiotherapy (high-risk patients without recurrence). (cancerlive.net)
secondary end points were regional recurrence, contralateral breast cancer, distant metastases, and overall survival (OS). (cancertherapyadvisor.com)
Although radiotherapy reduces ipsilateral breast tumor recurrence, the absolute reduction is very small (2.4%)," Dr. Kunkler reported. (cancertherapyadvisor.com)
No significant differences were observed in regional recurrence, contralateral breast cancer, or distant metastases. (cancertherapyadvisor.com)
What this study shows is that for every 100 women (from our selected population) treated with radiotherapy, one will have a recurrence anyway, four will have a recurrence prevented, but 95 will have had unnecessary treatment," said Dr. Kunkler. (cancertherapyadvisor.com)
Had these women not had radiotherapy, they would have been able to have minor surgery and radiotherapy following a recurrence," he said. (cancertherapyadvisor.com)
Radiotherapy should not be omitted in patients with estrogen-receptor poor, high-grade tumors, where risk of recurrence is relatively high. (cancertherapyadvisor.com)
The primary end point was invasive disease-free survival (defined as freedom from ipsilateral invasive breast tumor recurrence, ipsilateral locoregional invasive breast cancer recurrence, contralateral invasive breast cancer, distant recurrence, or death from any cause). (nih.gov)
Among patients with HER2-positive early breast cancer who had residual invasive disease after completion of neoadjuvant therapy, the risk of recurrence of invasive breast cancer or death was 50% lower with adjuvant T-DM1 than with trastuzumab alone. (nih.gov)
Within the accuracy of the study, the risk of a local tumor recurrence in the breast is similar and non-breast cancer death is reduced. (zeiss.com)
Possible mechanisms for gram for breast cancer in southern Sweden issued 1991, pre- recurrence after treatment are low initial drug sensitivity or menopausal lymph node positive (N+) breast cancer patients an acquired drug resistance. (lu.se)

SAN ANTONIO-Women 65 years of age or older who receive hormone therapy after breast-conserving surgery for hormone receptor-positive axillary node-negative breast cancer may omit whole breast radiotherapy, results of a global phase 3 study concluded at the 2013 San Antonio Breast Cancer Symposium. (cancertherapyadvisor.com)
Single dose intra-operative radiotherapy for early stage breast cancer can be a better alternative to conventional whole breast radiotherapy for most patients during primary tumor management ' stated the principal investigator Professor Jayant Vaidya, Professor of Surgery and Oncology and Scientific Director at University College London when presenting the results of the study. (zeiss.com)

Both chemotherapy and radiotherapy reduce the risk of breast cancer recurring and the risk of dying from breast cancer. (cochrane.org)
However, it has also been suggested that using chemotherapy and radiotherapy at the same time may be more toxic than keeping them separate. (cochrane.org)
This review examined the current evidence on the best way to administer chemotherapy and radiotherapy following breast-conserving surgery. (cochrane.org)
The limited evidence available does suggest that the frequency and severity of side effects of chemotherapy and radiotherapy are similar regardless of which sequence is used. (cochrane.org)
Present study shows that chemotherapy and radiotherapy there was no significant difference in the order, according to patient selection and treatment of habitual decision, when the lymph nodes, it can first chemotherapy. (cancerlive.net)
she had a history of breast cancer, which had been treated with chemotherapy and radiotherapy 7 years earlier, and bronchiectasis. (cdc.gov)

Single dose intraoperative radiotherapy (SD-IORT) is an effective and convenient treatment for women who have been diagnosed with early stage breast cancer. (spirehealthcare.com)

The new study, based on data from Sweden and Denmark of women treated with radiotherapy for invasive breast cancer, found a linear increase in the rate of heart disease associated with the dose of radiation received by the heart. (cardiobrief.org)
Delivering fewer radiotherapy sessions of lower intensity over a shorter period of time after surgery for some people with invasive breast cancer has a positive impact on patients and the NHS, according to new guidance from NICE. (hospitalhealthcare.com)
Until recently, standard practice for people with invasive breast cancer having surgery was to have 15 radiotherapy fractions giving a total of 40 units of radiation (Gy) over three weeks. (hospitalhealthcare.com)
Commenting on the widespread benefits of the new guidance, Jonathan Benger, NICE's chief medical officer, said: 'Lower intensity, shorter duration radiotherapy in response to pandemic pressures and NICE's rapid Covid-19 guidelines for some people with invasive breast cancer is now embedded in practice and already reaping rewards. (hospitalhealthcare.com)
You may be incorporating additional surgery such as reconstructive surgery, so breast-conserving surgery is always considered less invasive, less morbid," she said. (medscape.com)
Patients with invasive breast cancer treated with breast conserving surgery are usually offered radiotherapy. (ncin.org.uk)
In 2006, 74% of patients aged 70 and over with conservatively treated invasive breast cancer had radiotherapy treatment recorded compared with 84% of those aged under 70. (ncin.org.uk)
The management of non-invasive breast disease is studied in the Sloane Project which is funded by the NHS Breast Screening Programme. (ncin.org.uk)
Patients who have residual invasive breast cancer after receiving neoadjuvant chemotherapy plus human epidermal growth factor receptor 2 (HER2)-targeted therapy have a worse prognosis than those who have no residual cancer. (nih.gov)
We conducted a phase 3, open-label trial involving patients with HER2-positive early breast cancer who were found to have residual invasive disease in the breast or axilla at surgery after receiving neoadjuvant therapy containing a taxane (with or without anthracycline) and trastuzumab. (nih.gov)
Invasive cancers. (webmd.com)
It accounts for about 10% of invasive breast cancers. (webmd.com)
There are data suggesting that radiotherapy (RT) following breast conserving surgery (BCS) for invasive carcinoma may not be necessary in some elderly patients. (biomedcentral.com)
range: 70 - 87 years) patients (analysed as 93 'patients' due to one patient having bilateral cancers) managed in a dedicated breast clinic and who underwent BCS for invasive carcinoma was carried out. (biomedcentral.com)
Adjuvant radiotherapy to the breast after breast conserving surgery (BCS) is the mainstay of treatment to achieve local control in patients with invasive carcinoma. (biomedcentral.com)
Searching the patient database identified 92 patients with primary invasive breast carcinoma over the age of 70 during this period who were treated with BCS as the primary treatment. (biomedcentral.com)

The main mortality risks from the side-effects of regional node radiotherapy, heart disease and lung cancer, vary according to organ dose. (esmo.org)
For example, patients may need to choose between mastectomy or breast conserving surgery (BCS), whether to have radiotherapy after BCS, what type of radiotherapy (eg, whole breast, partial breast, accelerated partial breast irradiation, boost dose) to have, whether to undergo a lymph node biopsy, and whether to opt for primary endocrine therapy instead of surgery or radiation. (medscape.com)
A relationship between mean heart dose (MHD) and acute coronary event (ACE) rate was reported in a study of patients with breast cancer (BC). (rug.nl)
In order to accurately determine a reasonable target and minimize the dose distribution of the affected lung and heart dose, retained breast after radiation therapy, should be selected to CT simulation in order to ensure, in CT imaging-based radiation therapy. (cancerlive.net)
New ways of targeting tumours more precisely have helped increase the effectiveness of radiotherapy - increasing the dose that can safely be given while minimising damage to surrounding tissues. (icr.ac.uk)
Our initial results showed that when the total dose is adjusted appropriately it is safe to deliver radiotherapy in fewer doses and now we can confirm that this is still the case 10 years down the line," commented study co-leader Professor Judith Bliss, Professor of Clinical Trials at The Institute of Cancer Research, London, and director of its Cancer Research UK-funded Clinical Trials and Statistics Unit. (international-pharma.com)
High-dose radiation at a young age (patients with lymphoma) results in cell loss and premature fibrotic aortic valve stenosis as opposed to the degenerative calcific stenosis observed in patients with breast cancer. (mdrresearch.nl)
Our findings suggest a possible dose-dependent effect of radiotherapy on aortic valve fibrosis. (mdrresearch.nl)
Use of targeted intra-operative radiotherapy (TARGIT), as a single dose - with ZEISS INTRABEAM - directly after removal of a tumor, confirmed as non-inferior, when compared with external beam radiotherapy (EBRT). (zeiss.com)
Adjuvant radiotherapy with a total dose of 50 Gy was performed for each participant. (ac.ir)
Using 15-15 MV photon beam energies field can significantly reduce the absorbed dose to the thyroid gland and consequently can reduce the risk of developing hypothyroidism in breast cancer patients treated with radiotherapy. (ac.ir)

According to findings of the FAST trial, five larger radiotherapy doses after surgery - once-a-week sessions for five weeks instead of daily radiotherapy over the same time, totalling 25 doses - cause similarly low rates of side-effects in women with early-stage breast cancer in the long run. (international-pharma.com)
Researchers have shown that a smaller number of larger radiotherapy doses can cut radiotherapy treatment from four weeks to five days, meaning patients need fewer hospital visits. (ogkologos.com)

The findings are reported by investigators from the Early Breast Cancer Trialists' Collaborative Group (EBCTCG) on 3 November 2023 in The Lancet . (esmo.org)
It formed the foundation of a clinical trial reviewed by NICE as part of its updated guideline on the diagnosis and management of early and locally advanced breast cancer , published on 14 June 2023. (hospitalhealthcare.com)
Breast;68: 133-141, 2023 Apr. (bvsalud.org)
Abuja, 6 February, 2023 - Gloria Orji was 35 years old when she was diagnosed with stage 2 breast cancer in June 2010. (who.int)
In her message to commemorate the 2023 event, WHO Regional Director for Africa, Dr Matshidiso Moeti, says approximately 1.1 million new cancer cases occur each year in Africa, with about 700,000 deaths. (who.int)

Some women with early-stage, low-risk breast cancer may not need radiotherapy after breast conserving surgery according to new research led by McMaster University, BC Cancer, Hamilton Heath Sciences, and the University of British Columbia. (news-medical.net)
The research, published in The New England Journal of Medicine on Aug. 17, shows women 55 or older with a specific subtype of Stage 1 breast cancer can be effectively treated with just surgery and endocrine therapy. (news-medical.net)
Women with early breast cancer who have breast conserving surgery typically receive radiation to the breast daily for several weeks to reduce the risk of cancer returning in the breast. (news-medical.net)
With this new approach, a significant proportion of women can be spared of radiation after breast conserving surgery. (news-medical.net)
The study was coordinated by the Ontario Clinical Oncology Group at Hamilton Heath Sciences, and followed 500 women from across Canada who were 55 years of age or older, had undergone breast conserving surgery, and their tumours were smaller than two centimetres without cancer in the lymph nodes under the arm. (news-medical.net)
After surgery for localised breast cancer, radiotherapy (RT) improves both local control and breast cancer-specific survival. (cochrane.org)
It can occur as a result of damage to the lymphatic system, for example because of surgery or radiotherapy to the lymph nodes under the arm and surrounding area. (breastcancernow.org)
From July 2011 to July 2018, BC patients receiving 5.7 Gy once a week for 5 weeks to the whole breast after breast-conserving surgery were considered for the study. (nih.gov)
Also at the session, Jennifer Tseng, MD, medical director of breast surgery at City of Hope Orange County Cancer Center, Irvine, California discussed de-escalation of locoregional therapy. (medscape.com)
At present, more than 70% of women with breast cancer in this older population will receive axillary surgery and/or radiation. (medscape.com)
But for many patients with early, node-negative breast cancers with favorable tumor characteristics, less extensive surgery may be an appropriate option, especially for patients who have other significant comorbidities, Tseng said. (medscape.com)
The cohort consisted of 910 consecutive female patients with BC treated with radiotherapy (RT) after breast-conserving surgery. (rug.nl)
A specialist breast cancer doctor takes a sample of cancer cells during a biopsy or surgery to test for these receptors. (macmillan.org.uk)
Chemotherapy , along with surgery and radiotherapy , is the most effective treatment for triple negative breast cancer. (macmillan.org.uk)
You may be more likely to have chemotherapy as your first treatment before surgery to remove the cancer. (macmillan.org.uk)
From January 2000 to December 2007, 131 consecutive patients aged 75 years or older received adjuvant radiotherapy after breast conserving surgery. (unict.it)
Radiotherapy after breast-conserving surgery, (a) Indications: Postoperative radiation therapy is reserved for follow-up treatment of breast surgery, both the indications consistent. (cancerlive.net)
Patients before radiotherapy after surgery should make the necessary checks before the treatment. (cancerlive.net)
In general, radiotherapy and surgery are considered the most effective treatment options for cancer, with around 30 per cent of men with prostate cancer receiving radiotherapy as their main treatment. (icr.ac.uk)
Impact of diabetes on surgery and radiotherapy for breast cancer. (harvard.edu)
In the trial, 915 women from 19 centres across the UK who had early-stage breast cancer were assigned to one of three different courses of radiotherapy following breast cancer surgery - a regimen of daily doses and two courses delivering five larger doses once weekly, all over the same time period of five weeks. (international-pharma.com)
Surgery aims to remove all cancer cells from the breast. (bcna.org.au)
Breast-conserving surgery (also called lumpectomy) involves removing only the cancerous part of the breast. (bcna.org.au)
Radiotherapy (also called radiation treatment) uses X-rays to kill any cancer cells that may be left in the breast or lymph nodes under the arm (axilla) after surgery. (bcna.org.au)
It is more common after breast-conserving surgery but is sometimes recommended after a mastectomy. (bcna.org.au)
Ca breast ug lecture ajay khanna department of surgery. (slideshare.net)
Amounts of 49 males and 680 postmenopausal females with primary non-metastatic BC who underwent breast surgery at Mauriziano Hospital or IRCCS Candiolo (TO-Italy) were included. (mdpi.com)
A surgical guidance system used to accurately pinpoint the location of a tumour in the breast before surgery. (cromwellhospital.com)
Her breast cancer is at Stage 2 and required six courses of chemotherapy, surgery, and 25 sessions of radiotherapy which lasted 5 weeks. (who.int)
Radiotherapy was delivered to ipsilateral axil- cancer patients in the future, it is essential to increase our lary and supraclavicular lymph nodes and the remaining knowledge in mechanisms responsible for drug resistance, breast parenchyma after breast conservation surgery or tho- and to define reliable indicators for response to therapy. (lu.se)
The study was carried out to exhaust the scientific literature regarding surgery associated with radiotherapy in patients suffering from metastatic spinal cord compression and to assist in the decision of oncology physicians and professionals in choosing the best treatment for the patient. (bvsalud.org)
Objective: To evaluate the impact of physical therapy on the quality of life of patients after breast cancer surgery. (bvsalud.org)
Methods: We included 16 female patients who underwent breast cancer surgery in this clinical, longitudinal, prospective, and convenience sample study. (bvsalud.org)
Conclusion: According to the data presented in this study, we suggest that a physiotherapeutic approach positively impacts the quality of life of patients after breast cancer surgery. (bvsalud.org)
The inclusion criteria were: patients who went to the UEAFTO, Breast cancer is the type of cancer that most affects women had undergone surgery less than three years prior, were older around the world. (bvsalud.org)
A single patient was excluded due to an MRI artifact caused by a hemostatic substance injected near the target during surgery preceding radiotherapy. (lu.se)

However, some of those studies irradiated just the breast or chest wall, but others also irradiated some of the regional lymph nodes. (esmo.org)
The meta-analysis performed by EBCTCG investigators shows that regional lymph node irradiation clearly reduces breast cancer mortality and that the effect appears to be driven by internal mammary node radiotherapy. (esmo.org)
In this meta-analysis of individual patient data, the EBCTCG investigators sought data from all randomised studies of regional lymph node radiotherapy versus no regional lymph node radiotherapy in women with early breast cancer, including one study that irradiated lymph nodes only if the cancer was right-sided. (esmo.org)
Swelling of the arm, hand, chest or breast area caused by a build-up of lymph fluid in the surface tissues of the body. (breastcancernow.org)
An ultrasound scan uses sound waves to produce a picture of the breast tissue and the lymph nodes (glands) in the armpit. (macmillan.org.uk)
I've had a mastectomy, lymph node clearance and 7 sessions of chemo and today went to be measured up for radiotherapy. (breastcancernow.org)
1. Without making clear the axillary lymph nodes are required to include the breast, chest wall, ipsilateral axillary and supraclavicular lymph node area. (cancerlive.net)
2. Axillary lymph node removal were done without lymph node metastasis (detected at least 10 or more) only the breast and chest wall irradiation. (cancerlive.net)
Irradiated lymph node metastasis of breast, chest wall, axillary and supraclavicular. (cancerlive.net)
It can grow larger in your breast and spread to nearby lymph nodes or through your bloodstream to other organs. (webmd.com)
This rare cancer begins in blood or lymph vessels in the breast tissue or in the skin of the breast. (webmd.com)

This is a major advance in our treatment approach for breast cancer. (news-medical.net)
The only systematic difference between treatment groups was in regional node radiotherapy to the internal mammary chain, supraclavicular fossa, or axilla, or any combinations of these. (esmo.org)
Given the widespread use of radiation therapy in the treatment of breast cancer, and the continually expanding arsenal of novel therapies, the current study calls for greater collaboration between oncologists and cardiologists. (cardiobrief.org)
An important lesson for the oncologist may be that the time to address concerns about cardiovascular "survivorship" is at the time of cancer diagnosis and before treatment rather than after completion of therapy. (cardiobrief.org)
If you're over the age of 45 and you need a small tumour removed (less than 3cm in diameter), your breast consultant will probably recommend this treatment. (spirehealthcare.com)
You may also have stiffness and discomfort around the shoulder and breast or chest area during and after treatment. (breastcancernow.org)
It's particularly useful when there are multiple treatment options, when there's uncertainty regarding the evidence or uncertainty regarding which patients may benefit or on the outcome, when there are both treatment advantages and disadvantages that patients must weigh, and when the decision is high impact, like for breast cancer treatment," she said. (medscape.com)
Knowing this helps your cancer doctor plan the best treatment for you. (macmillan.org.uk)
Your cancer doctor will talk to you about the best treatment for you. (macmillan.org.uk)
Always tell your cancer doctor or breast care nurse about treatment side effects you have. (macmillan.org.uk)
Souchon, R & Dunst, J 2011, ' The challenge of integrating radiotherapy in the multimodal treatment of breast cancer ', Breast Care , vol. 6, no. 5, pp. 345-346. (uni-luebeck.de)
After having my lump removed with clear margins I've decided the last minute to cancel my radiotherapy treatment. (breastcancernow.org)
A medical paper has been written that states this particular pneumonia can be caused by radiation treatment for breast cancer. (breastcancernow.org)
Gege Li spoke to several of our researchers here at The Institute of Cancer Research, London, who have pioneered improved use of radiotherapy in the treatment of prostate cancer. (icr.ac.uk)
With prostate cancer being the most common cancer in men in the UK and many other countries, and with more than 47,500 new UK cases and almost 12,000 deaths annually, there remains a need to improve our understanding of how to deliver treatment schedules to make them more effective and convenient. (icr.ac.uk)
Tony Herbert, who was diagnosed with prostate cancer in 2018, said: "My radiotherapy treatment was quite intense. (icr.ac.uk)
IMRT has provided a more dynamic, precise and technologically advanced treatment option for men with prostate cancer - and it has paved the way for developing streamlined treatment regimens to reduce the burden on patients, as well as on healthcare systems. (icr.ac.uk)
Evidence from ICR research and wider studies pointed to the idea of delivering smaller, higher doses of radiotherapy - an approach called hypofractionation, which might be able to reduce treatment toxicity without compromising cancer control. (icr.ac.uk)
IMRT used to be more costly because of long treatment times, and at the time it wasn't yet funded as a prostate cancer treatment. (icr.ac.uk)
Giving fewer but larger doses of radiotherapy is as safe in the long term for breast cancer treatment, according to the final results of a 10-year study. (international-pharma.com)
Moderate or severe long-term effects were low across the three treatment groups and the most common effect was breast shrinkage. (international-pharma.com)
Elderly breast cancer patients are less likely to receive surgical treatment or radiotherapy than younger patients. (ncin.org.uk)
Learning about breast cancer and its treatment may help you feel more in control. (bcna.org.au)
The treatment recommended for you will depend on the type of breast cancer you have and your personal situation. (bcna.org.au)
Here are a few common treatment options for breast cancer in men. (bcna.org.au)
Besides, radiotherapy carries its own health risks, particularly in the elderly, as well as the inconvenience of travel for daily treatment for 3 or 4 weeks. (cancertherapyadvisor.com)
The talks relate to the modern techniques of radiation therapy as an important part of cancer treatment and how the advancement of technology gives serious hope for the cure of many patients, allowing absolute precision in the targeting of radiation, without burdening healthy tissues. (newsbulletin247.com)
Breast cancer patients often engage in shared decision -making to select an individualized treatment regimen from multiple options. (bvsalud.org)
We evaluated decision regret and physical and psychological well-being among breast cancer patients who underwent adjuvant radiotherapy and explored their associations with patient , tumor , treatment , and symptom characteristics. (bvsalud.org)
Decision regret regarding the radiotherapy was assessed using the Ottawa Decision Regret Scale, physical and psychological well-being were assessed using the PROMIS Global Health -10 questionnaire , and patients were asked about their treatment outcomes and symptoms. (bvsalud.org)
Our findings suggest that psychological well-being influences patients ' satisfaction with therapy decisions, implying that practitioners should pay special attention to maintaining psychological well-being during shared decision -making and ensuring that psychological assessment and treatment is provided after cancer therapy to deal with long-term effects of radiotherapy . (bvsalud.org)
There are several barriers leading to inadequate cancer management in LATAM, including lack of treatment coverage, lack of access to specialised cancer care and geographical barriers, among others [ 24 ]. (ecancer.org)
Treatment of breast cancer in the elderly is controversial and is often extrapolated from their younger counterparts [ 1 ]. (biomedcentral.com)
A greater knowledge of breast cancer behaviour and optimal treatment in the elderly is urgently needed. (biomedcentral.com)
5 cm) in Nottingham have been managed in a dedicated Elderly Primary Breast Cancer Clinic according to a defined set of treatment guidelines. (biomedcentral.com)
The aims of the study are to compare male and female breast cancer (FBC) in terms of cancer clinical and anatomopathological features and treatment approach, and to identify differences between male BC and FBC in terms of survival. (mdpi.com)
The Times reports that early-stage cancer patients are benefiting from modified radiotherapy treatment across the NHS in response to the pandemic. (ogkologos.com)
The TARGIT-A trial has offered many breast cancer patients a treatment that is well tolerated, effective, convenient and highly cost efficient', summarized Professor William Small, Professor of Radio-oncology at Loyola University, Chicago and one of the world's leading radiation oncologists. (zeiss.com)
During treatment of breast cancer, Radiotherapy to the Supraclavicular fossa region results in absorption of radiation by the thyroid gland and consequently leads to hypothyroidism in 40% of patients. (ac.ir)
Battling cancer, you have no savings as everything goes into treatment to stay alive. (who.int)
During the course of her treatment in 2017, Ms Orji realized she had a big decision to make as she noticed patients like her depended on their families and themselves for information about their cancers. (who.int)
We needed a community where we could get the correct medical knowledge to make informed decisions and advocate for government to support cancer treatment in the country. (who.int)
Through the group, we have been able to use our voice to advocate for government support for cancer treatment in the country, and a notable success is that the National Health Insurance Act (NHIS) now covers some percentage of cancer treatment. (who.int)
Going through cancer and its treatment has changed me forever. (who.int)
Ms Orji, lamented that many cancer patients in the country could have survived but often present late to the hospital for treatment. (who.int)
In order to achieve a more effec- were recommended postoperative radiation and adjuvant tive and individualised chemotherapeutic treatment of breast chemotherapy. (lu.se)
Despite major progress in both diagnosis and treatment of cancer, the number of cases continues to rise. (lu.se)
Our mission is based on the national cancer guidelines and covers the entire chain from preventive measures via diagnosis and treatment to prevention of metastasis and end-of-life care", says Mef Nilbert. (lu.se)
Some factors such as individual treatment strategy, according to the histology of the primary tumor, plan of treatment strategies carried out in a multidisciplinary manner, risk-benefit of radiotherapy, assessment of the degree of spinal instability, improvement in communication and referral between specialists in oncology showed an increase in the survival of these patients. (bvsalud.org)
These findings are important for cancer treatment planning and help professionals to seek greater survival. (bvsalud.org)

Care for older women with a new diagnosis of early stage breast cancer is not one-size-fits all, and patients are faced with many decisions that may depend as much on personal preference as on clinical necessity, Schonberg said. (medscape.com)
It shows a decrease in the use of radiotherapy with age at diagnosis. (ncin.org.uk)
As breast cancer is often considered a "women's cancer" and is represented by the colour pink, your diagnosis may also leave you feeling uncomfortable and isolated. (bcna.org.au)
Co-author) Living with cancer : symptoms, diagnosis and treatments. (wikipedia.org)
It is a product of late stages diagnosis and deficient cancer care [ 46 ]. (ecancer.org)
Scientists have now come up with a new technology that involves cancer diagnosis through a simple urine test using a strip of paper, making diagnosis simple and affordable for people. (medicaldaily.com)

An updated search was carried out in the Cochrane Breast Cancer Group's Specialised Register (20 May 2011), MEDLINE (14 December 2011), EMBASE (20 May 2011) and World Health Organization (WHO) International Clinical Trials Registry Platform (20 May 2011). (cochrane.org)
CHICAGO - By definition, all clinical care is - or should be - patient-centered care, and that is especially true for older women with early stage breast cancer. (medscape.com)
Schonberg was speaking at a session on the management of care for older women with breast cancer held during the recent American Society of Clinical Oncology (ASCO) annual meeting. (medscape.com)
Results of the FAST trial, which was led by The Institute of Cancer Research, London, and funded by Cancer Research UK, are published in the Journal of Clinical Oncology . (international-pharma.com)
Where no radiotherapy is recorded this may be a data quality issue or there may be a clinical contra-indication. (ncin.org.uk)
The NCIN coordinates and develops analysis and intelligence to drive improvements in prevention, standards of cancer care and clinical outcomes for cancer patients. (ncin.org.uk)
Although the clinical relationship between thoracic radiotherapy and valvular dysfunction has been established, the process leading to accelerated aortic valve stenosis remains unclear. (mdrresearch.nl)
These excellent results provide real clinical justification for single intraoperative radiation in suitable patients with early breast cancer. (zeiss.com)
Our data have provided evidence for a comparable prediction of clinical outcome in CMF-treated breast cancer patients using conventional clinical variables and gene expression based markers. (lu.se)
Breast cancer is a heterogeneous disease with a large variabil- survival after adjuvant polychemotherapy was 10% (from ity in clinical outcome. (lu.se)
Conclusion: We report a successful clinical study of MRI-only brain radiotherapy, conducted using both prospective and retrospective analysis. (lu.se)

In an accompanied comment, Prof. Mark N Levine of the Department of Oncology, McMaster University in Hamilton, ON, Canada wrote that it is unclear how much of the effect of the radiotherapy occurred because of regional nodal irradiation. (esmo.org)
Purpose: Breast cancer survivors have a high risk of cardiac death as a consequence of heart irradiation during left breast tangential radiotherapy (RT). (unicatt.it)
Conclusions: Prospective-gating RT to the left breast offered the best protection of heart and lung, as well as a lower irradiation of the contralateral breast, compared to CRT or IMRT. (unicatt.it)
More decision regret was associated with volumetric modulated arc therapy , chest wall irradiation, use of docetaxel as a chemotherapy agent, lymphangiosis carcinomatosa, new heart disease after radiotherapy , and lower psychological well-being . (bvsalud.org)
Partial breast irradiation only treats some but not all of the breast, focusing on the area where the cancer is most likely to return, usually around the surgical cavity. (medlineplus.gov)

I underwent a biopsy, and cancerous cells were found in the breast tissue sample. (who.int)

35 years old who received neoadjuvant chemotherapy and mastectomy for Stage IIb to III breast cancer. (oncolink.org)

Trastuzumab emtansine (T-DM1), an antibody-drug conjugate of trastuzumab and the cytotoxic agent emtansine (DM1), a maytansine derivative and microtubule inhibitor, provides benefit in patients with metastatic breast cancer that was previously treated with chemotherapy plus HER2-targeted therapy. (nih.gov)

The purpose of the study was to evaluate the toxicity, local control, overall and disease-free survival of elderly breast cancer (BC) patients treated with adjuvant once-weekly ultra-hypofractionated radiotherapy (RT) either with intensity-modulated RT (IMRT) or 3D conformal RT (3DCRT). (nih.gov)
Intensity modulated radiotherapy (IMRT) - pioneered at the ICR - is one such approach which has improved outcomes and quality of life for many men with prostate cancer. (icr.ac.uk)

IMRT is a type of external-beam 'conformal' radiotherapy which shapes the radiation beam to match the contours of the tumour, delivering higher doses to target areas of the prostate while avoiding healthy organs and tissues. (icr.ac.uk)

The standard radiotherapy regimen consisted of the now outdated international standard of 50 Gray (Gy) of radiation, divided into 25 daily doses of 2 Gy, delivered every day over five weeks. (international-pharma.com)

Radiation therapy in breast cancer - Special topics for the breast surgeon ", under his direction Mr. Vasiliou Venizelou Surgeon, Director of the Breast Unit of the Metropolitan Hospital, President of EDEKMA and Mr. Athanasios Dimopoulos Director Coordinator of the Radiotherapeutic Oncology Department of the Metropolitan Hospital and Chairman of the Organizing Committee. (newsbulletin247.com)
The conference is organized by Hellenic Interdisciplinary Society of Breast Cancer (EDEKMA) in collaboration with its Radiation Oncology Center Metropolitan Hospital at the Royal Olympic Hotel. (newsbulletin247.com)
Jeffrey S. Tobias is a British professor of oncology at University College, London, and co-author of Cancer and its Management and Informed Consent in Medical Research. (wikipedia.org)
He is on the board at Cancer Research UK, and is a former president of the British Association for Head and Neck Oncology. (wikipedia.org)
More regional cancer genomic initiatives and public availability of this data are needed in order to develop more precise oncology in locally advanced breast cancer. (ecancer.org)
This means that there is the potential to prevent around 6 000 deaths each year, and this is a priority goal for research and the health service", says Mef Nilbert, Professor of Oncology at Lund University and head of the regional cancer centre for southern Sweden, RCC Syd. (lu.se)

The site contains links to prognostic calculators, information about time to benefit for various cancer screening programs based on life expectancy, and helpful information about communicating information about prognosis, risks, and benefits to patients. (medscape.com)
Increasing severity of co-morbidity may sufficiently shorten remaining life expectancy to cancel gains with adjuvant radiotherapy. (unict.it)

Radiation may also cause increases in pericardial disease, peripheral vascular disease, cardiomyopathy, valvular dysfunction, and arrhythmias, according to Moslehi, and other breast cancer therapies, such as anthracyclines and hormonal therapies, may have "additional cardiotoxic effects. (cardiobrief.org)

With a better understanding of the molecular biology of breast cancer we can now identify women who do not need radiation. (news-medical.net)
Their courage has led to a chance to improve care for many other women who we now know confidently will not need to undergo radiation therapy,' said Torsten Nielsen, clinician-scientist at BC Cancer and professor of Pathology & Laboratory Medicine, University of British Columbia. (news-medical.net)
Two of these, with 853 women, assessed radiotherapy and chemotherapy given at the same time versus chemotherapy given first followed by radiotherapy. (cochrane.org)
The third trial randomised 244 women to radiotherapy followed by chemotherapy versus chemotherapy followed by radiotherapy. (cochrane.org)
To determine the effects of different sequencing of adjuvant CT and RT for women with early breast cancer. (cochrane.org)
These data support the use of PMRT in young women with stage IIb-III breast cancer. (oncolink.org)
Currently more than 30% of new breast cancer diagnoses are in women age 70 and older, and estrogen receptor positive, HER2-negative disease is the majority biomarker profile. (medscape.com)
But triple negative breast cancer can develop in women of any age and ethnicity. (macmillan.org.uk)
Most women with triple negative breast cancer have no strong history of breast cancer in their family (hereditary breast cancer). (macmillan.org.uk)
But some women with triple negative breast cancer have an altered BRCA1 gene . (macmillan.org.uk)
1 in 8 Canadian women will be diagnosed with breast cancer. (breastcancerprogress.ca)
Before our practice-changing research in prostate cancer radiotherapy, ICR researchers including Professor Judith Bliss and Professor John Yarnold had already showed that hypofractionated radiotherapy had advantages for women with breast cancer without increasing side effects. (icr.ac.uk)
After receiving radiotherapy women were then assessed annually for up to 10 years by researchers for side effects to healthy breast tissue - including hardening of the breast, swelling, skin reactions and changes in breast size. (international-pharma.com)
The researchers observed no changes or minor changes in healthy breast tissue in 86% of all women in the trial at the 10-year time point. (international-pharma.com)
The majority of breast cancers are diagnosed in women over 50 years of age. (ncin.org.uk)
Women aged 71-73 years will be included in the planned extension of the screening programme outlined in the Cancer Reform Strategy (England) which is likely to result in a greater proportion of screen-detected breast cancers in this age group in future. (ncin.org.uk)
Among women, breast cancer is the second most common cancer diagnosed, after skin cancer. (webmd.com)
Breast cancer is a highly prevalent malignancy causing ≈45,000 deaths every year in women in Latin America (LATAM) and the Caribbean [ 33 ]. (ecancer.org)
It has been suggested that breast cancer may follow a less aggressive course in older women. (biomedcentral.com)
Breast cancer is the most common type of cancer in the UK, experienced by around one in eight women. (cromwellhospital.com)
We developed our breast care diagnostic pathway to provide women with rapid access to diagnostic services in suspected cases of breast cancer. (cromwellhospital.com)
The decision has been backed up in a pioneering study by the Institute of Cancer Research, which found women with early-stage breast cancer can be successfully treated in this way. (ogkologos.com)
Meanwhile, in Nigeria, WHO, with funding from the Susan Thompson Buffet Foundation, provides catalytic support to five states (Anambra, Ondo, Kebbi, Niger and Ekiti) to enable routine cervical cancer secondary prevention services across primary healthcare facilities, to reach up to 5,000 women per state. (who.int)

Among estrogen-receptor rich patients, the difference is 3.2% without radiotherapy versus 0.8% with radiotherapy ( P = 0.003). (cancertherapyadvisor.com)

When you support Breast Cancer Canada, you are helping to improve and save lives through better treatments and early detection of breast cancer. (breastcancerprogress.ca)
At the ICR, we are interested in how to make cancer treatments kinder and more practical for patients. (icr.ac.uk)
In breast cancer, we are waiting for the results of large basket trials to incorporate the detection of actionable mutations to select targeted treatments, in a similar way to the management of lung cancer. (ecancer.org)
We offer the most advanced breast cancer treatments available, including chemotherapy, radiotherapy and more. (cromwellhospital.com)
We provide some of the latest, most advanced treatments for breast cancer, delivered by an expert team of oncologists , nurse specialists and other sup porting healthcare professionals. (cromwellhospital.com)
The major challenge is putting in the effort to refine cancer treatments, which requires a lot of resources, and to getting people to really change their lifestyles in order to reduce their risk of cancer. (lu.se)
Most of the treatments administered to fight cancer are pre- ded: patients with locoregional disease or a distant active dise- pared and directed at the disease. (bvsalud.org)

In the past decade, several randomized trials and meta-analyses have displayed improvements in local control and overall survival with postmastectomy radiotherapy (PMRT) for locally advanced breast cancer, but have failed to report age-specific results. (oncolink.org)
With increasing use of neoadjuvant chemotherapy in this population, a recent retrospective review has suggested continued improvement to local control and cancer specific survival over all age groups. (oncolink.org)
When detected in its early stages, breast cancer is highly treatable with good survival rates. (cromwellhospital.com)

The paper "Surface guided radiotherapy (SGRT) improves breast cancer patient setup accuracy" was recognized as one of the most read in Journal of Applied Medical Physics. (lu.se)

A total 28 patients had previously undergone radiotherapy for breast cancer or malignant lymphoma. (mdrresearch.nl)

By the early 2000s, our researchers were keen to explore whether a switch to using hypofractionated IMRT for prostate cancer could have benefits for both patient safety and for the efficiency of care. (icr.ac.uk)

This prevents the cancer cells from growing and dividing, and leads to cell death. (medlineplus.gov)

Brain metastasis is a dreaded complication that significantly reduces the quality of life in breast cancer patients . (bvsalud.org)
The data of breast cancer patients with brain metastasis who were treated with WBRT using cobalt -60 equipment between 2005 and 2009 were retrospectively collected from the departmental medical record unit. (bvsalud.org)
One explanation is that the population is ageing and the risk of cancer increases with age", says Mef Nilbert, who has conducted research on heredity and risk of cancer metastasis. (lu.se)

However, a lumpectomy may be an option for small cancers. (bcna.org.au)

With 18 months of median follow-up, severe early-late toxicity (G3) was reported in terms of fibrosis and breast retraction, both with an incidence of 1.4%, mostly in the 3DCRT group. (nih.gov)
We conclude that compliance with adjuvant radiotherapy is good and rate of toxicity is acceptable in elderly patients. (unict.it)

Shorter intensity and duration of radiotherapy means that for every 1,000 people receiving the lower number of fractions, 10,000 NHS radiotherapy appointments have been freed up in England every year, reducing pressure on services and allowing the NHS to see more people. (hospitalhealthcare.com)
Early studies suggested that prostate cancer, too, might be more sensitive to larger fractions than smaller ones. (icr.ac.uk)

We invite you to read about our progress and meet the researchers advancing breast cancer in Canada. (breastcancerprogress.ca)
Our researchers have been central in conducting research in this area that has underpinned new standards of care for prostate cancer, leading to substantial benefits for both patients and healthcare systems across the world. (icr.ac.uk)
Researchers found that people with better oral health - those having natural teeth and more frequent dental visits - had better chances of surviving head and neck cancers. (medicaldaily.com)

35 years old with stage II-III breast cancer treated with doxorubicin-based neoadjuvant chemothe. (oncolink.org)
This retrospective review of the experience of MD Anderson Cancer Center was conducted to evaluate the effect of PMRT after neoadjuvant chemotherapy in young patients. (oncolink.org)
At present, recommendations regarding PMRT in patients receiving neoadjuvant chemotherapy for breast cancer are unclear. (oncolink.org)

Around 26,700 people have radiotherapy for early and locally advanced breast cancer each year in England. (hospitalhealthcare.com)

Patients receiving adjuvant chemotherapy should be in the early radiotherapy after chemotherapy (usually not more than 16 weeks). (cancerlive.net)

The aim of this study was to determine whether increased inflammatory cell infiltration, fibrosis, and calcification is present in aortic valves after radiotherapy at the time of aortic valve replacement. (mdrresearch.nl)

This retrospective analysis aimed to address the efficacy of BCS without adjuvant radiotherapy in the elderly population. (biomedcentral.com)

Radiotherapy to the armpit will make the underarm hair fall out on that side. (breastcancernow.org)

Coronavirus reports: "As a Black man with advanced prostate cancer, who. (ogkologos.com)
Prostate cancer cell, coloured scanning electron micrograph (SEM). (lu.se)
Prostate cancer is most prevalent in men over 50 years of age. (lu.se)

In situ cancers. (webmd.com)

Breast cancer in the elderly may follow a less aggressive course. (biomedcentral.com)

They really wanted me to have this as I had stage 3 Aggressive cancer with a lump of 4.3 mm which appeared 6 months after mammogram. (breastcancernow.org)
A lump under the breast, which you may or may not feel, is usually the first sign of breast cancer. (webmd.com)
For many people, the first sign of breast cancer is a lump in the breast. (cromwellhospital.com)
Screening with a mammogram can also detect breast cancer before a lump appears. (cromwellhospital.com)
A lump or thickening in your breast. (cromwellhospital.com)
She recounted detecting a lump in her breast during self-examination and informed a friend, who advised her to visit the hospital for a medical check. (who.int)
It may involve placing a radioactive source into the surgical site after the surgeon removes a breast lump. (medlineplus.gov)
After breast lump removal, there is a cavity where the cancer was removed. (medlineplus.gov)

Starting 5 years after radiotherapy, and with no sign of a threshold, the risk for major coronary events increased by 7.4% per gray. (cardiobrief.org)
75 years with early (stage) breast cancer. (unict.it)
Eighty-two patients received radiotherapy in combination with 5 years of hormone therapy with tamoxifen or aromatase inhibitor. (unict.it)
Equity of Cancer and Diabetes Co-Occurrence: A National Study With 44 Million Person-Years of Follow-Up. (harvard.edu)
Although those over 70 years may self-refer, in 2006 only 9% of breast cancers in patients 70 years and over were screen-detected (Figure 1). (ncin.org.uk)
In Australia, 87 per cent of men diagnosed with breast cancer are alive five years later. (bcna.org.au)
71.1 years in the no radiotherapy arm and 70.9 years in the arm receiving radiotherapy. (cancertherapyadvisor.com)
The questionnaire was administered 14 months to 4 years after completion of radiotherapy . (bvsalud.org)
Some take years to spread beyond your breast, while others grow and spread quickly. (webmd.com)

As a result, the trials do not assess the modern types of radiotherapy, and new types of chemotherapy (such as taxanes) or other drugs (such as Herceptin). (cochrane.org)

A new study published in the New England Journal of Medicine offers the best look yet at the increased risk for heart disease produced by radiotherapy for breast cancer. (cardiobrief.org)
This study confirms the importance of reducing exposure of the heart to radiation to avoid excess risk of ACEs after radiotherapy for BC. (rug.nl)
The aim of this study was to assess the impact on local control of the omission of radiotherapy in "low-risk" older patients. (cancertherapyadvisor.com)
Methods: Patients with early left breast cancer, referred for adjuvant RT to our institution, were enrolled in this study. (unicatt.it)
The aim of this study was to compare thyroid gland radiation absorption during radiotherapy with different anterior-posterior beam radiation of 6-15 and 15-15 MV photon beam energies. (ac.ir)
29 patients with breast cancer were recruited to this study. (ac.ir)

Anatomy11

Organisms2

Diseases52

Chemicals and Drugs53

Analytical, Diagnostic and Therapeutic Techniques and Equipment92

Psychiatry and Psychology2

Phenomena and Processes42

Disciplines and Occupations3

Anthropology, Education, Sociology and Social Phenomena1

Humanities1

Information Science9

Named Groups2

Health Care36

Geographicals2

Postoperative radiotherapy8

Recurrence23

Whole breast radiotherapy2

Chemotherapy and radiotherapy6

Intraoperative radiotherapy1

Invasive16

Dose11

Larger radiotherapy doses2

20235

Surgery36

Lymph11

Treatment50

Diagnosis6

Clinical11

Irradiation5

Underwent1

Mastectomy1

Metastatic breast cancer1

Intensity-Modulated2

Conformal1

Doses1

Oncology6

Life expectancy2

Valvular dysfunction1

Women23

Versus1

Treatments7

Survival3

Improves1

Undergone1

IMRT1

Dividing1

Metastasis3

Small cancers1

Toxicity2

Fractions2

Researchers3

Neoadjuvant3

Locally1

Adjuvant chemotherapy1

Fibrosis1

Retrospective analysis1

Armpit1

Prostate3

Situ1

Elderly1

Lump8

Years9

Trials1

Study6