Radiotherapy anticancer drugs or radiation. Medical search. Frequent questions

This very short-range delivery of energy permits highly targeted therapies, since the radiation-emitting nuclide will be in close proximity to the delivery site (e.g. (wikipedia.org)
Various therapies including radiotherapy can induce autophagy in many kinds of cancer cells. (biomedcentral.com)
In response to metabolic stress and anticancer therapies, autophagy is also required for cancer cells to survive [ 20 ]. (biomedcentral.com)
Gastrointestinal complications are common in patients undergoing various forms of cancer treatments, including chemotherapy, radiation therapy, and molecular-targeted therapies. (bvsalud.org)
Participants who have adverse event (AEs) due to previous anticancer therapies must have recovered to =Grade 1 or baseline. (who.int)
The combination therapy is able to remarkably enhance effect of chemotherapy or radiotherapy, prevent and minimize toxic side effect of these therapies and raise resection rate in operation. (kanglaite.com)
We use a broad range of standard and state-of-the-art treatment options including surgery, radiation, medical oncology, including molecular targeted therapies, and immunotherapy. (mountsinai.org)

The toxic side effects of chemotherapy and radiation make the cure often seem as bad as the ailment, and there is also the threat of recurrence and tumour spread. (theconversation.com)
Laboratory trials have found that the drug, may kill up to 95% of solid tumour cells when combined with radiation or chemotherapy. (bris.ac.uk)
Defects can occur at any point along these pathways, leading to malignant transformation of the affected cells, tumour metastasis and resistance to anticancer drugs. (biomedcentral.com)

Locally advanced cervical cancer: Should intensity-modulated radiotherapy replace brachytherapy? (urotoday.com)

Auger therapy is a form of radiation therapy for the treatment of cancer which relies on low-energy electrons (emitted by the Auger effect) to damage cancer cells, rather than the high-energy radiation used in traditional radiation therapy. (wikipedia.org)
Similar to other forms of radiation therapy, Auger therapy relies on radiation-induced damage to cancer cells (particularly DNA damage) to arrest cell division, stop tumor growth and metastasis and kill cancerous cells. (wikipedia.org)
It differs from other types of radiation therapy in that electrons emitted via the Auger effect (Auger electrons) are released with low kinetic energy. (wikipedia.org)
Standard treatment for locally advanced stage cervical cancer (stage IIB to IVA) is 'concurrent chemoradiation' when anticancer drugs are given during the same treatment period as pelvic radiotherapy (radiation therapy to lower abdomen). (cochrane.org)
6. Palliative radiation therapy completed ≤ 7 days prior to start of study drugs. (astrazenecaclinicaltrials.com)
7. No other anti-cancer therapy (chemotherapy, immunotherapy, hormonal anti-cancer radiotherapy [except for palliative local radiotherapy]), biological therapy or other novel agent is permitted while the patient is receiving study medication. (astrazenecaclinicaltrials.com)
treatment options for mesothelioma patients, including a recently-approved combination drug therapy. (nolo.com)
Radiation therapy is one of the most important options for cancer treatment. (emergency.co.jp)
Depending on the type and stage of cancer, initial treatment, preoperative radiation therapy, postoperative radiation therapy, and symptomatic treatment are provided. (emergency.co.jp)
It is more precise than regular x-ray therapy and can deliver higher doses of radiation to cancerous tissue, minimizing damage to surrounding normal tissue. (emergency.co.jp)
Compared to other radiation therapy modalities, heavy particle therapy tends to reduce complications. (emergency.co.jp)
It enhances the effect of radiation therapy and destroys cancer cells more effectively. (emergency.co.jp)
Radiation therapy is used to stimulate the immune system to attack cancer cells. (emergency.co.jp)
Surgery to the extent that this is feasible in terms of safety, followed by involved-field radiation therapy and concomitant and maintenance chemotherapy with temozolomide, has set the standard of care since 2005. (frontiersin.org)
Surgery, chemotherapy, and radiation therapy are still the main treatment methods, but each method has its limitations and risks. (frontiersin.org)
Reducing hypoxia may have sensitizing effects on radiotherapy, chemotherapy, phototherapy, acoustic therapy and so on. (frontiersin.org)
Although FAP has limited expression in normal adult tissues, it is highly expressed in the tumor microenvironment of many solid cancers - a characteristic that makes it an ideal target for anticancer therapy. (doaj.org)
In this study, we constructed a nano-drug delivery system (NPF@DOX) targeting FAP to increase the therapeutic efficiency of synergistic chemo-photothermal therapy against OSCC.Methods: We utilized PEGylated nano-graphene oxide (NGO) to link doxorubicin (DOX) and fluorescently-labeled, FAP-targeted peptide chains via hydrogen bonding and π-π bonding to enhance the targeting capability of NPF@DOX. (doaj.org)
Following the induction therapy, patients without disease progression received twice-weekly gemcitabine at 40 mg/mÂ² and radiation. (cancernetwork.com)
The combination of concurrent fluorouracil (5-FU)and ionizing radiation therapy for patients with unresectable disease hasresulted in a twofold increase in median survival: approximately 10 months vs 5months. (cancernetwork.com)
Radiotherapy is a local anti-cancer therapy, which uses ionizing radiation to cause inhibition of cell division and ultimately lead to cell death. (bvsalud.org)
Approximately 95%-98% of new anti-cancer drugs actually fail phase III clinical trials , the phase in which new treatments are compared with existing therapy options. (theconversation.com)
Treatment may consist of some combination of surgery, chemotherapy, and radiation therapy. (wikipedia.org)
KLT can be used alone or combined with chemotherapy or radiation therapy or applied peri-operationally. (kanglaite.com)
The FDA has granted Fast Track and Breakthrough Therapy designations to avasopasem for the reduction of severe oral mucositis induced by radiotherapy. (galeratx.com)
The Company's second product candidate, rucosopasem manganese (rucosopasem), is in clinical-stage development to augment the anti-cancer efficacy of stereotactic body radiation therapy in patients with non-small cell lung cancer and locally advanced pancreatic cancer. (galeratx.com)
From previous our studies, to control tumor microenvironment is expected to be necessary for reducing cancer resistance for tumor therapy, We deliberately changed and designed an experimental design to establish a therapeutic method in which the effects of conventional anticancer drugs, radio sensitizers and radiotherapy reproduce the most promising environment and lead to higher antitumor effects. (nii.ac.jp)
Moreover, the new agent combined with conventional anticancer agents, radiation therapy or photodynamic therapy exerted a high antitumor effect. (nii.ac.jp)
The results demonstrate that the cytotoxicity of disulfiram was copper-dependent, the molar excess of disulfiram relative to copper resulted in attenuation of disulfiram-mediated cytotoxicity, copper was required for the radiosensitizing activity of disulfiram, and copper-complexed disulfiram enhanced the efficacy not only of external-beam radiation but also of targeted radionuclide therapy in the form of (131)I-MIBG. (strath.ac.uk)
The organic performance of the therapy appears to be because of the local deposition of radiation dosage near the nanoparticles. (kxcad.net)
Smartly engineered nanocapsules can not only shrink and decompose into small-sized nanodrugs upon drug release but also can regulate the TME to overproduce reactive oxygen species for enhanced synergistic therapy in tumors. (nature.com)
There was a clinical trial a few years ago where there was no significant difference in survival based on receiving postoperative therapy or not, and there was some increased toxicity in patients who received therapy postoperatively because of radiation to the heart. (medscape.com)
Also, our radiation therapy techniques, our ability to understand damage to the heart and estimate radiation damage to the heart, which is critical for assessing the toxicity of radiation, have gotten so much better. (medscape.com)
Radiation therapy uses high-powered energy beams or particles to target cancer cells and kill them. (mountsinai.org)
Drug therapy-Adverse effects. (bvsalud.org)
8. Meraw SJ, Reeve CM. Dental considerations and treatment of the oncology patient receiving radiation therapy. (bvsalud.org)
10. Garg AK, Malo M. Manifestations and treatment of xerostomia and associated oral effects secondary to head and neck radiation therapy. (bvsalud.org)
This heterogeneity affects response to surgery and/or systemic therapy, and also facilitates inherent and acquired drug resistance. (cdc.gov)
In an exploratory analysis of the final reporting of the ABRAZO trial -a phase 2 study of talazoparib following platinum or multiple cytotoxic regimens in metastatic BRCA1/BRCA2 mutations-among those who received talazoparib after platinum-based therapy, anticancer activity appeared to be greater in patients who were further away from receiving platinum therapy. (medscape.com)

However, the efficacy of traditional treatments is hindered by systemic toxicity, limited therapeutic effects, and drug resistance. (doaj.org)
Galera Therapeutics, Inc. is a clinical-stage biopharmaceutical company focused on developing and commercializing a pipeline of novel, proprietary therapeutic candidates that have the potential to transform radiotherapy in cancer. (galeratx.com)

Itraconazole, a common triazole anti-fungal drug in widespread clinical use, has evidence of clinical activity that is of interest in oncology. (ecancer.org)
Principles and practice of radiation oncology. (bvsalud.org)

The role of radiotherapy and chemoradiation in the management of primary liver tumours. (cancercentrum.se)

Current treatments for gliomas use chemotherapy, radiotherapy, tyrosine kinase inhibitors, monoclonal antibodies and surgery, but each of the treatment strategies has several serious side effects. (frontiersin.org)
The treatments are chemotherapy, radiotherapy, and surgery. (healthforworld.com)
Chemotherapy and radiotherapy are broad-based treatments which attack the bulk of cancer cells but also damage healthy tissue. (theconversation.com)

The other discussion that came up in that neoadjuvant session was about the use of postoperative radiotherapy. (medscape.com)
Every single randomized trial ever done has shown a clear improvement in control in the chest with postoperative radiotherapy. (medscape.com)

This review evaluated whether giving additional anticancer drugs (ACTs) after standard treatment could help women with locally advanced cervical cancer to live longer compared with standard treatment alone. (cochrane.org)
We considered the findings to be at high risk of bias in this trial, as women were given different drugs during standard treatment, and so the overall effect of the study treatment could not be attributed to the ACT alone. (cochrane.org)
We found insufficient evidence to support giving additional anticancer drugs to women who have received standard treatment for locally advanced cervical cancer, as currently only limited data are available from two very different trials. (cochrane.org)
In Japan, research and development of radiation technology in cancer treatment is active, and medical teams with advanced technology and expertise provide optimal treatment for patients. (emergency.co.jp)
A treatment in which a radiation source is inserted near or inside cancerous tissue. (emergency.co.jp)
This is a special cancer treatment in which a boron drug is administered to the cancer patient, followed by neutron irradiation of the cancer tissue. (emergency.co.jp)
This treatment delivers a high dose of radiation to cancerous tissue with minimal damage to surrounding normal tissue. (emergency.co.jp)
An increasingly popular strategy is pharmaconutrition, which combines a tailored pharmacological treatment with a diet designed to synergize the effects of drugs. (frontiersin.org)
Multimodal strategies for tumor diagnosis and treatment based on nanomaterials and nanotechnology represent highly relevant challenges for the future of anticancer treament. (frontiersin.org)
Treatment of anal squamous cell carcinoma is with the combination of radiation and chemotherapy, including 5-fluorouracil and mitomycin at the beginning and at the end of a 4- to 6-week radiation regimen. (medscape.com)
The primary treatment strategy of NPC is radiotherapy. (biomedcentral.com)
Past history of interstitial lung disease (ILD), drug-induced ILD, radiation pneumonitis which required steroid treatment, or any evidence of clinically active interstitial lung disease. (astrazenecaclinicaltrials.com)
highly effective methods of contraception during the duration of the study and will continue following the last dose of study treatment for the longest duration stated on the label of each of the given drugs (depending on each arm). (ucsd.edu)
The Company intends to gain an understanding from the FDA of its evaluation of avasopasem for radiotherapy-induced severe oral mucositis (SOM) in patients with head and neck cancer undergoing standard-of-care treatment and next steps to support an NDA resubmission. (galeratx.com)
Rucosopasem was granted Orphan Drug Designation by the FDA for the treatment of pancreatic cancer. (galeratx.com)
and the Company's ability to achieve its goal of transforming radiotherapy in cancer treatment with its selective dismutase mimetics. (galeratx.com)
Numerous phytochemicals and their determined analogs have been recognized as possible contender for anticancer treatment and the present review article sheds light on few of these phytocompounds. (researchsquare.com)
A drug called lenalidomide works well in people with less aggressive (low/intermediate risk) MM when used after a stem cell transplant, known as 'maintenance' treatment. (roche.com)
Granisetron is usually taken only on the day of treatment with chemotherapy or radiation. (anticancercure.com)
Granisetron is not likely to be useful if you keep taking it during times when you are not receiving chemotherapy or radiation treatment. (anticancercure.com)
Smart drug delivery systems (SDDSs) for cancer treatment are of considerable interest in the field of theranostics. (nature.com)
However, many troubling questions arise with the use of new drugs or treatment strategies that are designed to enhance apoptosis and critical tests must be passed before they can be used safely in human subjects. (biomedcentral.com)
Radiation is frequently used as well, and is usually the primary treatment for non-Hodgkin lymphoma. (rxwiki.com)
Prevention and treatment of the consequences of head and neck radiotherapy. (bvsalud.org)

This disease is traditionally treated through a combination of surgery, radiotherapy, and chemotherapy. (doaj.org)
If the growth can't be cut out through surgery, it may be burnt away with radiation or poisoned by chemotherapy. (theconversation.com)
High-grade glioma (HGG) are optimally treated with maximum safe surgery, followed by radiotherapy (RT) and/or systemic chemotherapy (CT). (surgicalneurologyint.com)

Additionally, the drug uptake efficiency in vitro, photo-thermal properties, release performance, and anti-tumor effects of NPF@DOX were evaluated and further demonstrated in vivo.Results: Data derived from FT-IR, UV-Vis, and TEM implied successful construction of the NPF@DOX nano-drug delivery system. (doaj.org)
The evidence for these anticancer effects, in vitro , in vivo , and clinical are summarised, and the putative mechanisms of their action outlined. (ecancer.org)
Although establishment of a radiation resistant in vitro condition has been difficult, we find out inhibitor of Carbonic anhydrase 9, which could control hypoxic condition, and it showed the effect of suppressing metastasis and tumor invasion, itself. (nii.ac.jp)

Our synthetic strategy provides a platform for next generation smart nanocapsules with enhanced permeability and retention effect, multimodal anticancer theranostics, and biodegradability. (nature.com)

Also known as stereotactic ablative radiotherapy, this approach is used to treat early-stage lung cancers. (mountsinai.org)

KLT will also be approved as an anticancer new drug since active substance, molecular structure, anticancer mechanism at molecular level, clinical efficacy and safety have been scientifically defined, extensively studied, carefully evaluated and strictly examined before approval. (kanglaite.com)

In addition, nanomaterials combined with chemotherapeutic drugs can can induce deleterious oxidative stress in tumor sites, consume GSH and other antioxidant substances to alter cell REDOX homeostasis and achieve anti-tumor effect. (frontiersin.org)

Granisetron is used to prevent nausea and vomiting that may be caused by medicine to treat cancer ( chemotherapy or radiation). (anticancercure.com)
Your doctor may want you to take only one dose, up to 1 hour before chemotherapy or radiation. (anticancercure.com)
Tell your doctor if you forget to take your dose within 1 hour before chemotherapy or radiation. (anticancercure.com)

Complications related to radiotherapy can be both acute and chronic. (bvsalud.org)

Triple negative breast cancer, which affects around one in seven breast cancer patients and is resistant to hormonal drugs, was the focus of the study. (mental-fitness-group.com)

Sensitization of cancer cells to conventional drugs using multi-target agents that block survival and oncogenic pathways, alone or in combination, is an emerging strategy to overcome drug resistance. (researchsquare.com)

We aimed to deploy our proprietary technologies to develop proof-of-concept formulations and then enter into licensing agreements with third party pharmaceutical companies.In order to make the Company more investable and secure additional financing, the Board decided to reposition the Company as a therapeutics (as opposed to drug delivery) company in early 2023. (marketscreener.com)

The synergistic interaction between disulfiram and radiotherapy was evaluated by combination-index analysis. (strath.ac.uk)

A combination of radiotherapy and anticancer drugs is used to increase the sensitivity of cancer cells. (emergency.co.jp)
Research has looked at using combretastatins in combination with other anti-cancer agents such as carboplatin, cisplatin, vinblastine and also using radiotherapy with very encouraging results. (bris.ac.uk)
Researchers hope that using lenalidomide in combination with drugs designed to help a person's own immune system target and destroy cancer cells, like cevostamab, will provide better health outcomes for people with high-risk MM after a transplant. (roche.com)
The purpose of this clinical trial is to test the safety and effectiveness of cevostamab in combination with lenalidomide and how the body processes these drugs. (roche.com)
Therefore, disulfiram may have anticancer potential in combination with radiotherapy. (strath.ac.uk)

Moreover, according to the requirements of US Food and Drug Administration (FDA), theranostic agents should be completely cleared from the body within a reasonable period of time. (nature.com)
Such data chal enge the "ca- and in experimental animals, with The four anticancer agents dis- nonical" site-specificity of carcino- reference to the possible underlying cussed here were first used in clin- ical practice in the 1960s, but since genesis. (who.int)

Women who have postmenopausal status due to either surgical/natural menopause or chemical ovarian suppression (initiated at least 28 days prior to Day 1 of Cycle 1) with a gonadotropin-releasing hormone (GnRH) agonist such as goserelin or radiation-induced ovarian suppression. (researcherprofiles.org)

Chemotherapy includes cytotoxic drugs, which block the activity of cancer cells by targeting intracellular DNA, RNA, or proteins. (bvsalud.org)

With the development of tumor molecular heterogeneity theory(12), there are still some patients with GIST who are sensitive to radiotherapy, especially for the patients with advanced stage(13-16).In addition, with the development of imaging technology and modern tissue and organ radiation technology, it has become a reality to concentrate high-dose radiation locally in abdominal cavity tumors(12), which challenges RT's insensitivity to GISTs. (researchsquare.com)
It is particularly suitable for pediatric cancer patients because it minimizes the effects of radiation on the growing tissue. (emergency.co.jp)
This multi-institution phase II trial of induction irinotecan/gemcitabine followed by twice-weekly gemcitabine and upper abdominal radiation has been initiated to determine the activity of this regimen in patients with unresectable pancreatic cancer. (cancernetwork.com)
Immunocompromised patients are often treated prophylactically with triazole anti-fungal drugs, including ITZ, particularly if there is a risk of aspergillosis . (ecancer.org)
We heard stories from our European colleagues about how phase 3 trials were completed and regulatory bodies approved an agent for use, but then there was a 1- to 2-year process to get payers to agree to make that drug available to patients. (medscape.com)

Based on the agreement with the U.S. Food and Drug Administration (FDA) on Special Protocol Assessments for two phase 3 studies with ceftobiprole - one in Staphylococcus aureus bacteremia (SAB) and one in acute bacterial skin and skin structure infections (ABSSSI) - Basilea is in preparation to initiate these studies. (basilea.com)

1993. Protective effects of chlorogenic acid, curcumin and beta-carotene against gamma-radiation-induced in vivo chromosomal damage. (cdc.gov)

Another procedure to kill cancer cells and shrink the tumors is through using high-energy rays called radiation. (healthforworld.com)

The mechanism of synergism may be through IM to inhibit p53, a signal pathway of radiation damage repair. (researchsquare.com)

24th Canadian Association of Radiation Oncologist Scientific meeting. (usherbrooke.ca)
However, developing SDDSs with early diagnostic capability, enhanced drug delivery and efficient biodegradability still remains a scientific challenge. (nature.com)
Scientific progress and new drug innovation don't take place in a vacuum. (blogspot.com)

Phytochemicals are viewed as appropriate possibility for anticancer medication advancements due to their pleiotropic activities on track occasions with numerous habits. (researchsquare.com)

2012) Directeur, axe de recherche en imagerie médicale et radiothérapie. (usherbrooke.ca)
2e Congrès International - Radiations Médicales: Recherche et Applications. (usherbrooke.ca)

1986. Carcinogenic effects of radiation on the human skin. (cdc.gov)

Furthermore, NPF@DOX exhibited a high photothermal conversion efficiency (52.48%) under near-infrared radiation. (doaj.org)

Inflammatory Drugs and Risk of Breast Cancer: Evidence from a General Female Population and a Mammographic Screening Cohort in Sweden. (cancercentrum.se)

Radiation Research Radiation Research, 186(5): 520-530 (2016). (usherbrooke.ca)
Radiation Physics and Chemistry 128, 36-43 (2016). (usherbrooke.ca)
Invest New Drugs 34, 269-276 (2016). (usherbrooke.ca)

It is more precise than regular X-ray irradiation and delivers a higher dose of radiation to cancer tissue. (emergency.co.jp)

Distribution to hard sites (brain, retina, lump, intracellular organelles) and also drugs with serious adverse effects (e.g., anticancer representatives). (kxcad.net)
Radiotherapy-Adverse effects. (bvsalud.org)

Chemotherapy is the use of anticancer drugs to kill cancer cells. (hemorrhoidstalk.com)
Most drugs are made to target "bulk" cancer cells, but not the root cause: the cancer stem cell. (theconversation.com)

On the contrary, small size NPs with a diameter of 4-20 nm easily penetrate into deep tumor tissues, but they are more prone to rapid clearance and insufficient drug retention. (nature.com)

If the cancer is still on its first stage, anticancer drugs injected through intravenous or the chemotherapy procedure is usually done. (healthforworld.com)
INTRODUCTIONHeadquartered in Cardiff, UK, and quoted on NASDAQ in the US, Biodexa is a clinical-stage biotechnology company with three enabling drug delivery technologies. (marketscreener.com)
SYNOPSIS at the same stage and have similar histologic features, it Drug Administration-approved Hybrid Capture II (Digene is diffi cult to predict the outcome. (cdc.gov)

Proton beams can reach depths where radiation has the greatest effect when focused on cancerous tissue. (emergency.co.jp)
Then we aim radiation beams at the tumor from several directions. (mountsinai.org)

1998. Food preservation using ionizing radiation. (cdc.gov)

Gemcitabine administered via a twice-weekly schedule results in an enhanced radiation-sensitizing effect. (cancernetwork.com)
Additionally, based on the properties summarised previously, it is proposed that itraconazole may synergise with a range of other drugs to enhance the anti-cancer effect, and some of these possible combinations are presented in the supplementary materials accompanying this paper. (ecancer.org)

Anatomy8

Organisms2

Diseases53

Chemicals and Drugs69

Analytical, Diagnostic and Therapeutic Techniques and Equipment83

Phenomena and Processes35

Disciplines and Occupations9

Technology, Industry, Agriculture4

Information Science5

Health Care28

Therapies7

Tumour3

Intensity-modulated1

Therapy39

Therapeutic2

Oncology2

Chemoradiation1

Treatments3

Postoperative2

Treatment24

Surgery3

Vitro3

Multimodal1

Stereotactic1

Efficacy1

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Chemotherapy or radiation3

Complications1

Hormonal1

Resistance1

Therapeutics1

Synergistic1

Combination5

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Patients5

Acute1

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Scientific3

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Breast cancer1

20163

Irradiation1

Adverse2

Cancer cells2

Insufficient1

Stage3

Beams2

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Effect2