AnatomyDiseasesChemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and EquipmentPhenomena and ProcessesDisciplines and OccupationsHealth Care
Yttrium RadioisotopesEmbolization, TherapeuticMicrospheresTechnetium Tc 99m Aggregated AlbuminHolmiumLiver NeoplasmsYttrium IsotopesStandard of CareChemoembolization, TherapeuticBrachytherapyRadiopharmaceuticalsCarcinoma, HepatocellularRadiobiologyNeuroendocrine TumorsGamma CamerasMultimodal ImagingRadioisotopesInjections, Intra-ArterialTomography, X-Ray ComputedInfusions, Intra-ArterialTomography, Emission-Computed, Single-PhotonTreatment OutcomeRadiotherapy DosageRadiation DosagePositron-Emission TomographyRetrospective StudiesColorectal NeoplasmsLiverDisease Progression
Hepatocellular carcinomaTAREChemoembolizationSelective internaEmbolizationMalignanciesMicrospheresHepatic RadioembolizationDosimetryUnresectableStereotactic body radiation therapyHolmium-166Liver metastasesInterventional radiologistProcedureTherapiesTumorViable treatment optionChemotherapyAbstractSystemicSecondaryConclusionsSBRTLesionsClinicalTherapyMetastaticRadiologistsCancerPatientsProceduresIncreasinglyIncludeEvidenceResearchStayImprove
Hepatocellular carcinoma6
  • The FDA approved TheraSphere Y-90 Glass Microspheres, a radioembolization technology, for the treatment of patients with hepatocellular carcinoma (HCC), according to a press release. (dryouramnassirmd.com)
  • Trans-arterial radioembolization (TARE) is a recognized, although not explicitly recommended, experimental therapy for unresectable hepatocellular carcinoma (HCC). (oncotarget.com)
  • Candidates for radioembolization include patients with: 1) Unresectable liver cancer of primary or secondary origin, such as hepatocellular carcinoma and liver-metastases from a different origin (e.g. colorectal cancer, breast cancer, neuroendocrine cancer, cholangiocarcinoma or soft tissue sarcomas) 2) No response or intolerance to regional or systemic chemotherapy 3) No eligibility for potentially curative options such as radiofrequency ablation. (wikipedia.org)
  • Transarterial radioembolization (TARE) with yttrium 90 is increasingly utilized for the treatment of hepatic neoplasms, whether primary (particularly hepatocellular carcinoma [HCC]) or metastatic (particularly colorectal). (thieme-connect.com)
  • Evolution of radioembolization in treatment of hepatocellular carcinoma: a pictorial review. (thieme-connect.com)
  • 6 Tohme S, Bou Samra P, Kaltenmeier C, Chidi AP, Varley PR, Tsung A. Radioembolization for hepatocellular carcinoma: a nationwide 10-year experience. (thieme-connect.com)
TARE5
  • What Is Radioembolization (TARE-Y90)? (kidshealth.org)
  • The full name of this treatment is transarterial radioembolization with yttrium-90 (TARE-Y90). (kidshealth.org)
  • Selective internal radiation therapy (SIRT), also known as transarterial radioembolization (TARE), radioembolization or intra-arterial microbrachytherapy is a form of radiation therapy used in interventional radiology to treat cancer. (wikipedia.org)
  • This review summarizes the different IR treatment options in HCC, including various ablative therapies, Transarterial Chemoembolization (TACE), Transarterial Radioembolization (TARE), Portal Vein embolization, emphasizing patient selection, procedural considerations and response evaluation. (thieme-connect.de)
  • Background: Transarterial radioembolization (TARE) has recently been recognized as a bridging/downstaging therapy to surgery for early hepatocellular carcinomas (HCCs) with high rates of complete pathological necrosis (CPN) on liver explants. (bvsalud.org)
Chemoembolization1
  • Therefore, locoregional therapies such as transarterial chemoembolization or radioembolization, can selectively be administered in the arteries that are supplying the tumors and will preferentially lead to deposition of the particles in the tumor, while sparing the healthy liver tissue from harmful side effects. (wikipedia.org)
Selective interna2
  • Background: Radioembolization, also known as transarterial radioembolization or selective internal radiation therapy with yttrium-90 (90Y) resin microspheres, is an established treatment modality for patients with primary and secondary liver tumors. (unav.edu)
  • Within the setting of hepatic neoplasia [primary and secondary], selective internal radiation therapy [SIRT], also known as radioembolization has become an accepted procedure, incorporated into the armamentarium of multidisciplinary oncologic care. (hilarispublisher.com)
Embolization2
  • Because this treatment combines radiotherapy with embolization, it is also called radioembolization. (wikipedia.org)
  • Prophylactic embolization of the gastroduodenal and right gastric arteries is not routinely necessary before radioembolization with glass microspheres. (ouhsc.edu)
Malignancies3
Microspheres5
  • The way radioembolization is performed is continuously evolving, pushed by technical innovations, the current availability of three different types of microspheres and increasing insight into the need for patient-specific dosimetry. (cirse.org)
  • Objective: The main objective is to collect data on the clinical application of radioembolization with 90Y resin microspheres to improve the understanding of the impact of this treatment modality in its routine practice setting. (unav.edu)
  • Radioembolization of symptomatic,unresectable neuroendocrine hepatic metastases using yttrium-90 microspheres. (unina.it)
  • 9 d'Abadie P, Hesse M, Louppe A, Lhommel R, Walrand S, Jamar F. Microspheres used in liver radioembolization: from conception to clinical effects. (thieme-connect.com)
  • Ho)-labeled microspheres are used for therapeutic radioembolization, ideally directly followed by SPECT imaging for dosimetry purposes. (dissem.in)
Hepatic Radioembolization1
  • Yttrium-90 hepatic radioembolization: clinical review and current techniques in interventional radiology and personalized dosimetry. (thieme-connect.com)
Dosimetry1
  • Y90 radioembolization dosimetry: concepts for the interventional radiologist. (thieme-connect.com)
Unresectable4
  • A patient with non-alcoholic fatty liver disease (NAFLD) and unresectable small-sized (≤3cm) diffuse liver metastases from adenocarcinoma of the rectosigmoid junction was assessed for treatment with transarterial radioembolization (SIRT). (scitechnol.com)
  • Purpose - To evaluate the downstaging efficacy of yttrium-90 radioembolization (Ytt-90)-associated with chemotherapy and the results of surgery for initially unresectable huge intrahepatic cholangiocarcinoma (ICC). (hal.science)
  • Conclusions - For initially unresectable huge ICCs, chemotherapy with Ytt-90 radioembolization is an effective downstaging method that allows for secondary resectability. (hal.science)
  • Yttrium-90 radioembolization for the treatment of solitary, unresectable HCC: the LEGACY Study. (thieme-connect.de)
Stereotactic body radiation therapy1
  • We hypothesize that the combination of 90 Y radioembolization to the parenchymal component of the tumor and stereotactic body radiation therapy (SBRT) to the vascular component is a safe and effective means of improving outcomes. (e-roj.org)
Holmium-1661
  • Holmium-166 radioembolization: current status and future prospective. (thieme-connect.com)
Liver metastases2
  • In this paper, we will review data presented at the annual meeting of ASCO 2014 about the Survival following Y90 radioembolization for neuroendocrine tumor liver metastases (Abstract #e15166). (unina.it)
  • Survival following Y90 radioembolization for neuroendocrine tumor liver metastases: A retrospective, single-center analysis. (unina.it)
Interventional radiologist1
  • The interventional radiologist will explain the risks and likely benefits of radioembolization. (kidshealth.org)
Procedure3
  • Radioembolization (ray-dee-oh-em-beh-lih-ZAY-shun) is a procedure used to treat some kinds of liver tumors . (kidshealth.org)
  • Radioembolization is our most used procedure to treat liver cancer. (moffitt.org)
  • The cutting-edge yttrium-90 radioembolization ("Y-90") procedure is a minimally invasive procedure to treat liver tumors. (uamshealth.com)
Therapies2
  • Treatment options include systemic therapy, surgery, arterially directed therapies such as radioembolization, or external beam radiation. (e-roj.org)
  • includes liver-directed therapies with Yttrium-90 radioembolization. (dukehealth.org)
Tumor2
  • Radioembolization goes through a blood vessel and right to the liver tumor. (kidshealth.org)
  • Surgical resection includes cholecystectomy, en bloc hepatic resection (typically of segments IVb and V), and lymphadenectomy with or without bile duct excision, depending on the location of the tumor. (medscape.com)
Viable treatment option2
  • Based on this evidence, until the results of the ongoing randomized trials become available, radioembolization appears to be a viable treatment option for intermediate-advanced stage HCC. (oncotarget.com)
  • Yttrium-90 ( 90 Y) radioembolization is one viable treatment option in patients unable to undergo surgery. (e-roj.org)
Chemotherapy1
  • Sometimes doctors use radioembolization with other treatments, like chemotherapy and surgery. (kidshealth.org)
Abstract1
Systemic2
  • For sufferers with liver prominent metastatic carcinoid (an illness that notably lacks accepted medications for systemic therapy), 90Y radioembolization could be used during development on somatostatin analogue therapy. (scapca.org)
  • For sufferers with pancreatic NET, radioembolization may be helpful being a bridge between systemic chemotherapeutic or targeted therapy regimens. (scapca.org)
Secondary1
  • Methods: Eligible patients are 18 years or older and receiving radioembolization for primary and secondary liver tumors as part of routine practice, as well as have signed informed consent. (unav.edu)
Conclusions2
  • The examples of sufferers in the average person disease subgroups had been too small to permit for significant conclusions regarding efficiency of radioembolization to be produced. (scapca.org)
  • Conclusions: The CIRT is the largest observational study on radioembolization to date and will provide valuable insights to the clinical application of this treatment modality and its real-life outcomes. (unav.edu)
SBRT2
  • A single center retrospective review identified 12 patients with cancers involving the liver who received both 90 Y radioembolization and SBRT to the PVTT between May 2015 to August 2020. (e-roj.org)
  • Combination 90 Y radioembolization and SBRT appears to be safe and effective in the treatment of PVTT. (e-roj.org)
Lesions1
Clinical1
  • The primary objective of the Cardiovascular and Interventional Radiological Society of Europe Registry for SIR-Spheres Therapy (CIRT) is to observe the clinical application of radioembolization. (unav.edu)
Therapy2
  • A small positron-generating branch in 90-Yttrium ((90)Y) decay enables post-therapy dose assessment in liver cancer radioembolization treatment. (maastrichtuniversity.nl)
  • The first patient in Singapore has been treated with TheraSphere radioembolization therapy- a treatment for primary liver cancer and metastatic bowel cancer. (europeanpharmaceuticalreview.com)
Metastatic1
  • 11 Lee EJ, Chung HW, Jo JH, So Y. Radioembolization for the treatment of primary and metastatic liver cancers. (thieme-connect.com)
Radiologists2
  • The treatment of liver tumors using yttrium-90 (Y-90) radioembolization brings unusual challenges for interventional radiologists. (auntminnie.com)
  • Please note that this course is open only to interventional radiologists who have completed their radiology training and performing radioembolization or planning to start with radioembolization. (cirse.org)
Cancer1
Patients3
  • Radioembolization can be considered a valuable treatment option for patients with intermediate-advanced HCC. (biomedcentral.com)
  • Since 2019, 8 patients have already been treated with liver radioembolization. (balthazarkorab.com)
  • However, objective response rates with 90 Y radioembolization alone in patients with PVTT are approximately 50% [ 7 ]. (e-roj.org)
Procedures1
  • Since much of the pre- and post-treatment phases consist of more routine diagnostic procedures, we will focus our attention on the aspects that are applicable to a complex case such as Y-90 radioembolization. (auntminnie.com)
Increasingly1
  • Radioembolization is increasingly performed throughout Europe. (cirse.org)
Include1
  • For the forthcoming scaling of the method, we must increase the production of microemboli and radiopharmaceuticals and prepare a whole galaxy of specialists capable of performing such jewelry operations, which include radioembolization," says Academician Kaprin. (balthazarkorab.com)
Evidence2
  • In this ESIR course, "Radioembolization of liver tumours", organised by Dr. Maarten Smits, Dr. Arthur Braat and Prof. Marnix Lam, attendees will learn about the fundamentals, latest evidence and techniques for performing radioembolization. (cirse.org)
  • Evidence supporting the use of radioembolization in HCC is mainly based on retrospective and prospective cohort studies. (oncotarget.com)
Research2
  • To conclude, 90Y radioembolization acquired a favorable basic safety profile within this potential research, which was comparable to published work previously. (scapca.org)
  • Physicians of the branch of the National Medical Research Center of Radiology - MRRC named after A.F. Tsyba in Obninsk, Kaluga region, began to carry out unique operations for radioembolization of the liver. (balthazarkorab.com)
Stay1
Improve1
  • While treatment with yttrium-90 ( 90 Y) radioembolization alone may improve outcomes, overall prognosis remains poor. (e-roj.org)