• In a Swedish population-based cohort study reported in JAMA Network Open , Mortezavi et al found that robot-assisted radical cystectomy with intracorporeal urinary diversion was associated with reduced all-cause mortality, reduced high-grade complications, and improved perioperative outcomes vs open radical cystectomy in patients with bladder cancer. (ascopost.com)
  • The study involved data from the Swedish National Register of Urinary Bladder Cancer and population-based Cause of Death Register on all patients who underwent radical cystectomy for bladder cancer between January 2011 and December 2018, with follow-up data collected through December 2019. (ascopost.com)
  • Objective: To evaluate long-term follow-up results of ERAS concepts in patients undergoing radical cystectomy for bladder cancer. (uni-muenchen.de)
  • Preoperative chemotherapy is underused in conjunction with radical cystectomy (RC) for muscle-invasive bladder cancer (MIBC) due to concerns for complications and delay of surgery. (diva-portal.org)
  • P = 0.054) did not affect CSS after radical resection of bladder cancer. (biomedcentral.com)
  • Prospective studies are needed to further confirm the predictive value of these variables for the prognosis of bladder cancer patients after radical cystectomy. (biomedcentral.com)
  • If you have bladder cancer or cancer that has spread from other areas into your bladder, you may need a radical cystectomy. (bladdercancer.net)
  • Radical cystectomy is a type of surgery where doctors remove your bladder and surrounding lymph nodes. (bladdercancer.net)
  • A radical cystectomy is complicated since your surgeon will need to move several organs in your belly around to remove your bladder. (bladdercancer.net)
  • Anterior exenteration or radical cystectomy is a major surgical procedure employed for the treatment of cancers of the anterior pelvic organs such as the reproductive organs and urinary bladder present in the front part of the pelvis. (urocare.co.uk)
  • Radical cystectomy is the removal of the entire bladder, nearby lymph nodes (lymphadenectomy), part of the urethra, and nearby organs that may contain cancer cells. (avocure.com)
  • And today he is going to talk to us about a recent publication from a study of his that talks about a very, very important thing for our patients, which is, their quality of life after surgery for bladder cancer, essentially, a radical cystectomy in this case. (urotoday.review)
  • Simple cystectomy: bladder removal. (pagniurologia.it)
  • As mentioned, in selected cases and in general for non-tumor pathologies, the removal can be limited to the bladder alone without removing the prostate, the seminal vesicles and the urethra in the man (superpullary cystectomy) or uterus and annexed in the woman. (pagniurologia.it)
  • After bladder removal (cystectomy) the gastrointestinal tract most suitable for urinary derivation will be identified and isolated. (pagniurologia.it)
  • INTRODUCTION & OBJECTIVES: Robot- assisted radical cystectomy is a widespread minimally invasive technique for the treatment of muscle-invasive and organ-limited bladder cancer in selected patients. (unifi.it)
  • CONCLUSIONS: Recent systematic reviews of literature reported that robot-assisted radical cystectomy with totally intracorporeal ileal bladder reconstruction represents a valid alternative to open surgery in selected patients with muscle-infiltrant bladder cancer. (unifi.it)
  • In the current study, we demonstrated the technical feasibility of the robotassisted radical cystectomy with totally intracorporeal ileal bladder reconstruction at our Institution. (unifi.it)
  • Objective To analyse the impact of centralisation of radical cystectomy (RC) provision for bladder cancer in England, on postoperative mortality, length of stay (LoS), complications and re-intervention rates, from implementation of centralisation from 2003 until 2014. (researcher-app.com)
  • Radical cystectomy plus ileal orthotopic bladder substitution is a choice for primary invasive bladder cancer and for high grade, refractory to conservative therapy, multifocal and quickly recurrent superficial bladder cancer, in young patients determined to maintain an adequate self corporeal image. (auro.it)
  • The aim of our study is to investigate functionally and oncologically the role of verumontanum as a landmark for the complete saving of striated sphincter in patients undergone radical cystectomy and ileal orthotopic bladder substitution. (auro.it)
  • From January 2008 to December 2012 we prospectively collected the data of 63 patients undergone radical retropubic cystoprostatectomy plus ileal orthotopic bladder substitution for clinically localized bladder cancer. (auro.it)
  • In our experience,the saving of verumontanum during radical cistectomy and ileal orthotopic bladder substitution improved overall and early continence recovery. (auro.it)
  • This study investigates the effect of PBT on overall (OS) and disease-free survival (DFS) in patients who underwent radical cystectomy for bladder cancer. (auanet.org)
  • Objective: The aim of this study was to identify clinicopathological variables associated with the clinical outcomes of patients with lymph node metastasis-positive urothelial bladder carcinoma after radical cystectomy. (elsevierpure.com)
  • Background: The present study sought to compare the differences in practice patterns, as well as clinical outcomes for patients with muscle-invasive bladder cancer undergoing treatment with either radical cystectomy (RC) or concurrent chemoradiaiton (CRT). (houstonmethodist.org)
  • Purpose: Patients with pathological T3N0 stage urothelial carcinoma of the bladder show a range of outcomes after radical cystectomy. (elsevierpure.com)
  • Given that nomograms have included heterogeneous groups of patients, we focused on and stratified patients with pT3N0 urothelial carcinoma of the bladder after radical cystectomy into prognostically different risk groups to facilitate the development of adjuvant therapy trials for those at high risk. (elsevierpure.com)
  • Materials and Methods: The study comprised a total of 578 patients from 9 centers worldwide with pT3N0 urothelial carcinoma of the bladder who underwent radical cystectomy without perioperative chemotherapy. (elsevierpure.com)
  • Conclusions: We constructed a user friendly prognostic risk model for patients with pT3N0 urothelial carcinoma of the bladder treated with radical cystectomy based on pT3 substage at radical cystectomy, lymphovascular invasion and margin status. (elsevierpure.com)
  • Objectives: To assess the efficacy of neoadjuvant chemotherapy (NAC) before radical cystectomy (RC) in a retrospective multicentre cohort of patients with cT2N0M0 bladder cancer (BCa) without preoperative hydronephrosis. (johnshopkins.edu)
  • Associations of self-efficacy, social support and coping strategies with health-related quality of life after radical cystectomy for bladder cancer: A cross-sectional study. (bvsalud.org)
  • Investigating associations between self - efficacy , social support and quality of life ( HRQoL ) and mediating effects of coping among bladder cancer (BC) patients treated with radical cystectomy (RC). (bvsalud.org)
  • Conclusions: The oncologic outcomes of patients with lymph node-positive bladder cancer treated with robot assisted radical cystectomy (RARC) compare favorably to previous published studies of open radical cystectomy at medium-term (mean follow-up of 42 months). (elsevierpure.com)
  • Radical cystectomy (RC) is the standard treatment for patients with muscle-invasive bladder cancer (BC), and it is also a valid option for selected patients with high-risk non-muscle-invasive BC. (biomedcentral.com)
  • The purpose of this study was to evaluate the effect on the lower skeletal muscle index (SMI) of short-term postoperative complications of radical cystectomy (RC) in patients with bladder cancer (BC). (biomedcentral.com)
  • WRAP-centralisation-radical-cystectomies-bladder-cancer-England-Parsons-2017.pdf - Accepted Version - Requires a PDF viewer. (warwick.ac.uk)
  • Radical Cystectomies performed for bladder cancer in England between 2003/2004 and 2013/2014 were analysed from Hospital Episode Statistics (HES) data. (warwick.ac.uk)
  • Valrubicin is indicated for intravesical therapy of BCG-refractory CIS of the urinary bladder in patients for whom immediate cystectomy would be associated with unacceptable morbidity or mortality. (medscape.com)
  • There are no established biomarkers to guide patient selection for neoadjuvant chemotherapy prior to radical cystectomy for muscle-invasive bladder cancer. (lu.se)
  • Among 889 patients undergoing robot-assisted radical cystectomy and 2,280 undergoing open radical cystectomy, a propensity score-matched cohort of 874 robot-assisted radical cystectomy patients and 1,154 open radical cystectomy patients was used for analysis. (ascopost.com)
  • Cancer-specific mortality rates were 27.6% (variance = 3.12%) in the robot-assisted radical cystectomy group vs 30.2% (variance = 1.59%) in the open radical cystectomy group at 5 years, and 30.3% (variance = 5.13%) vs 32.3% (variance = 1.91%) at 7 years ( P = .16). (ascopost.com)
  • On multivariate analysis, robot-assisted radical cystectomy was associated with significantly improved overall survival (hazard ratio = 0.71, 95% confidence interval [CI] = 0.56-0.89, P = .004). (ascopost.com)
  • The 30-day all-cause mortality rate was 0.9% for robot-assisted radical cystectomy vs 1.5% for open radical cystectomy (odds ratio [OR] = 0.58, 95% CI = 0.15-2.28, P = .44) and the 90-day mortality rate was 2.7% vs 4.2% (OR = 0.70, 95% CI = 0.32-1.54, P = .38). (ascopost.com)
  • However, robot-assisted radical cystectomy was associated with a higher 90-day rehospitalization rate vs open radical cystectomy (34.3% vs 26.1%, OR = 1.28, 95% CI = 1.02-1.60, P = .03). (ascopost.com)
  • The investigators concluded, "These findings suggest that compared with open radical cystectomy, robot-assisted radical cystectomy with intracorporeal urinary diversion was associated with a lower overall mortality rate, fewer high-grade complications, and more favorable perioperative outcomes. (ascopost.com)
  • MATERIAL & METHODS: Between February and October 2016, three consecutive robot -assisted radical cystectomy with extended pelvic lymphadenectomy and totally intracorporeal ileal Neobladder reconstructions were performed at our Institution with an innovative surgical technique. (unifi.it)
  • Objective: To describe the complications after robot-assisted radical cystectomy (RARC) using a standardized and validated reporting methodology. (elsevierpure.com)
  • Predictors of postoperative complications after robot-assisted radical cystectomy with extracorporeal urinary diversion. (endourology.ph)
  • Purpose: Robot-assisted radical cystectomy (RARC) is known to have less postoperative morbidity and complications than open radical cystectomy. (endourology.ph)
  • We are conducting a prospective RCT comparing open RC and RARC with mandated intracorporeal reconstruction (Robot-assisted Radical Cystectomy with intracorporeal urinary diversion versus Open Radical Cystectomy [iROC] trial) [6]. (shu.ac.uk)
  • Purpose: Previous studies have shown robot assisted radical cystectomy (RARC) to have comparable perioperative outcomes to open radical cystectomy. (elsevierpure.com)
  • For patients undergoing radical cystectomy, prospective data are still rare. (uni-muenchen.de)
  • This is a Phase 1 study designed to test the tolerability and feasibility of intravesical therapy with an attenuated Measles virus (MV-NIS) in patients with urothelial carcinoma who are undergoing radical cystectomy but are ineligible or do not desire neoadjuvant chemotherapy. (bcan.org)
  • Cheng KW, Shah A, Nassiri N, Ghodoussipour S, Miranda G, Cai J, Daneshmand S, Schuckman A, Djaladat H. Factors influencing ICU admission and associated outcomes in patients undergoing radical cystectomy with enhanced recovery pathway . (duke.edu)
  • This nation-wide population-based observational study does not suggest that preoperative chemotherapy, in a setting with high utilisation of such treatment, is associated with an increased risk of short-term complications in MIBC patients treated with radical cystectomy. (diva-portal.org)
  • Methods: Forty-six patients who underwent radical cystectomy without preoperative chemotherapy and had histologically proven nodal metastasis were included in the study. (elsevierpure.com)
  • Because secondary lesions contraindicate cystectomy and require aggressive chemotherapy, we performed further investigations. (cdc.gov)
  • Radical cystectomy is the primary treatment for T2 and T3 tumors, with consideration for neoadjuvant chemotherapy. (medscape.com)
  • Clinical evidence has demonstrated a overall survival benefit of neoadjuvant chemotherapy with methotrexate, vinblastine, doxorubicin, and cisplatin (MVAC), compared with cystectomy alone. (medscape.com)
  • Objectives: To assess the rate of urinary tract infection (UTI), the characteristics of the bacterial aetiological agents involved, the type and duration of antibiotics used, and the clinical risk factors of UTI in a multi-institutional cohort of patients who had undergone radical cystectomy (RC). (uni-regensburg.de)
  • Patients who have undergone radical cystectomy require routine surveillance to monitor for local recurrence or the development of metastatic disease. (medscape.com)
  • There's been a variety of quality of life studies in people that have undergone radical cystectomy but many of the studies have used sort of snapshot approaches to look at specific time points following surgery. (urotoday.review)
  • We identified 1,340 patients who underwent RC between 2011 and 2015 in Sweden due to MIBC according to the Swedish Cystectomy Register. (diva-portal.org)
  • Design, setting, and participants: Using the International Robotic Cystectomy Consortium (IRCC) database, we identified 939 patients who underwent RARC, had available complication data, and had at least 90 d of follow-up. (elsevierpure.com)
  • Data from 479 patients who underwent radical cystectomy at a single institution from January 2010 to December 2016 were analyzed. (auanet.org)
  • The patient underwent radical cystectomy with an orthotopic neobladder. (cdc.gov)
  • In 2002, UK policymakers introduced the Improving Outcomes Guidance (IOG) for urological cancers after a global cancer surgery commission identified substantial shortcomings in provision of care of radical cystectomies. (warwick.ac.uk)
  • How can we reduce the morbidity of patients undergoing robotic-assisted radical cystectomy with intracorporeal neobladder? (herts.ac.uk)
  • Previous literature recommended reduction of perioperative blood transfusion (PBT) post-cystectomy due to its association with inferior survival. (auanet.org)
  • One key recommendation was centralisation of cystectomies to high output centres. (warwick.ac.uk)
  • We evaluated the effect of pT3 substage at radical cystectomy, age, grade, lymphovascular invasion, margin status and number of lymph nodes removed on recurrence-free survival using Cox regression analysis. (elsevierpure.com)
  • The retained male urethra is at risk for cancer recurrence after radical cystoprostatectomy. (medscape.com)
  • Radical cystectomy (RC) with bilateral pelvic lymph node dissection is the gold standard for patients with localized muscle-invasive tumors. (biomedcentral.com)
  • In 2010, he was appointed consultant and pursued a surgical career in the procedure of removing part of a kidney using robotics and proceeded to regularly perform these, robotic radical prostatectomies and Holmium laser prostatectomies. (wikipedia.org)
  • He has since also regularly performed robotic radical prostatectomies and Holmium laser (HoLEP) prostatectomies. (wikipedia.org)
  • Some patients with more adverse pathology at the time of cystectomy (eg, locally advanced disease, lymph node metastases) may require more frequent imaging. (medscape.com)
  • Dr. Bochner highlights a number of factors that can be affected by having a radical cystectomy which is a significant surgery. (urotoday.review)
  • Radical cystectomy can be performed either via a traditional open surgery or robotically. (umms.org)
  • Pembrolizumab is indicated for treatment of BCG-unresponsive, high-risk NMIBC with carcinoma in situ (CIS) with or without papillary tumors in patients who are ineligible for, or have elected not to undergo, cystectomy. (medscape.com)
  • Electrothermal bipolar coagulation for radical prostatectomies and cystectomies: a preliminary case-controlled study. (medtronic.com)
  • Our results revealed that several clinicopathological characteristics can predict CSS risk after radical cystectomy. (biomedcentral.com)
  • Assessing the prognostic significance of specific clinicopathological features plays an important role in surgical management after radical cystectomy. (biomedcentral.com)
  • Cystectomy is the surgical excision of an ovarian cyst. (urocare.co.uk)
  • Radical cystectomy: as the total, plus the removal of regional lymph nodes. (pagniurologia.it)
  • OBJECTIVE To identify the likelihood of finding one or more positive lymph nodes (LNs) according to the number of LNs removed at radical cystectomy (RC), as the number of LNs removed affects disease progression and survival after RC. (elsevierpure.com)
  • And so what we wanted to do was just a large prospective, longitudinal study to really try to get a contemporary look at how patients do after radical cystectomy. (urotoday.review)
  • Radical cystectomy must be planned for the patient after the planned 18F-fluciclovine-PET/CT. (urotoday.com)
  • Ashish Kamat is joined by Bernard Bochner to discuss patient quality of life after a radical cystectomy. (urotoday.review)
  • Strict reporting of complications is necessary to advocate for radical cystectomy (RC) and helps in patient counseling. (elsevierpure.com)