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  • inhibitors
  • However, this conclusion is at odds with the emerging use of proteasome inhibitors as radio-sensitizers.We examined expression of PSMD9 using immunohistochemistry in a cohort of 157 breast cancer patients, including 32 cases (20.4%) that subsequently developed local recurrences.Our conclusion is compatible with use of proteasome inhibitors as radio-sensitizers, and highlights PSMD9 as a potential target for radio-sensitizing drugs. (nih.gov)
  • Our conclusion is compatible with use of proteasome inhibitors as radio-sensitizers, and highlights PSMD9 as a potential target for radio-sensitizing drugs. (nih.gov)
  • Catalytic Inhibitors of Topoisomerase II Are DNA-Damaging Agents: Induction of Chromosomal Damage by Merbarone and ICRF-187, Environmental and Molecular Mutagenesis, vol. 39, pp. 348-356 (2002). (freepatentsonline.com)
  • Cell Death
  • Immunohistochemical analysis using in situ end labeling (ISEL) and terminal deoxynucleotidyl transferase dUTP nick-end labeling (TUNEL) revealed increased cell death within tumors exposed to combined treatments compared with untreated tumors or tumors exposed to radiation alone. (biologists.org)
  • growth
  • This agent also inhibits pro-angiogenic factors such as vascular endothelial growth factor (VEGF) and displays immunomodulatory and pro-inflammatory properties by inducing various mediators of the inflammatory response. (nih.gov)
  • Class
  • Acromona, a synthetic antibacterial and antiprotozoal agent of the nitroimidazole class, is used against protozoa such as Trichomonas vaginalis , amebiasis, and giardiasis. (minclinic.ru)