• Recommendations on immunization following bone marrow transplantation will be published in a separate ACIP statement. (cdc.gov)
  • Several drug therapies are valuable in the treatment of symptomatic MM. Clinicians treat many patients with high-dose therapy and peripheral blood or bone marrow stem cell transplantation. (medscape.com)
  • Bone Marrow Transplantation. (bvsalud.org)
  • Most current gene therapies in humans involve taking cells out of the body, modifying them and putting them back in," said David T. Curiel, MD, PhD, distinguished professor of radiation oncology. (health.am)
  • Physics and imaging in radiation oncology. (lu.se)
  • Palifermin is used to prevent and to speed the healing of severe sores in the mouth and throat that may be caused by chemotherapy and radiation therapy used to treat cancers of the blood or bone marrow (soft fatty material in the middle of bones that makes blood cells). (medlineplus.gov)
  • This could stop the tumor growth itself or cooperate with standard chemotherapy and radiation to make them more effective. (health.am)
  • Dr. E. Donnall Thomas and his colleagues discovered a way to treat advanced leukemia by eradicating malignant white blood cells in the bone marrow using high doses of chemotherapy and radiation, and then replacing them with healthy donor cells. (fredhutch.org)
  • Without exotic treatment such as bone marrow transplant, death with this dose is common, due generally more to infection than gastrointestinal dysfunction. (wikipedia.org)
  • Volunteer donors having 100 per cent matching Human Lymphocyte Antigen (HLA) have been kept on standby for bone marrow transplant if their condition worsens," he said. (thehindu.com)
  • In an allogeneic stem cell transplant, the blood-forming stem cells in a patient's bone marrow are destroyed using high doses of chemotherapy or radiation therapy. (cancer.gov)
  • Recent work has demonstrated that DNA-damage pathways are activated very early in the process of tumor development, 89 and elegant epidemiologic studies demonstrated long ago that exposure to environmental agents contributes to the development of the vast majority of human cancers. (the-scientist.com)
  • Basal cell carcinomas, the commonest human skin cancers, consistently have abnormalities of the hedgehog signaling pathway and often have PTCH gene mutations. (nature.com)
  • For humans, exposure to radiation can cause anything from no clear effects or a mild burn to the destruction of bone marrow, birth defects, cancers and/or death. (millonpeskin.com)
  • This process can potentially eliminate some cancers derived from cells in the bone marrow, such as leukemia and lymphoma. (cancer.gov)
  • The data used in the study came from people receiving allogeneic stem cell and bone marrow transplants (BMTs). (nutraingredients.com)
  • The first bone marrow transplants were done on five Yugoslavian men with radiation damage, but unfortunately all of them were rejected (the bone marrow, not the men). (bcmj.org)
  • Humans have been attempting xenotransplants, also known as animal-to-human transplants, for hundreds of years with historically little success. (grunge.com)
  • And although the idea of informed consent gets murky when the options are between an extremely experimental procedure and death (in most instances), a surprisingly large number of people participated in these types of experiments, leading us to the pig-to-human heart transplants of the 21st century. (grunge.com)
  • A person, who was admitted to the AIIMS here after falling ill due to exposure to radiation, was today discharged after his condition improved while two other victims at the Army Research and Referral Hospital would be released soon as they have shown signs of recovery. (thehindu.com)
  • External exposure to radiation may occur from natural or man-made sources. (cdc.gov)
  • Pluri 's novel treatment, the PLX-R18, seeks to prevent bone marrow from declining as a result of exposure to radiation. (nocamels.com)
  • During or after exposure to radiation, the dosage should be increased to two full tablespoons of alginate four times daily to insure that there is a continual supply in the GI or gastrointestinal tract. (radiationdangers.com)
  • After an earthquake and subsequent tsunami critically damaged Japan's Fukushima nuclear power plant, workers and residents were imperiled by the risk of exposure to radiation. (millonpeskin.com)
  • The MRI techniques were also used to assess bone marrow fat and the thin cortical bone in the spine, where fractures typically occur. (europa.eu)
  • We are the first to use radiation-free CT-like MR imaging techniques in patient studies to simultaneously measure bone marrow and cortical bone tissue changes," says Karampinos. (europa.eu)
  • Human Immunodeficiency Virus (HIV) Infection and AIDS The human immunodeficiency virus (HIV) is a type of virus called a retrovirus. (merckmanuals.com)
  • Severe immunosuppression can be due to a variety of conditions, including congenital immunodeficiency, human immunodeficiency virus (HIV) infection, leukemia, lymphoma, generalized malignancy or therapy with alkylating agents, antimetabolites, radiation, or large amounts of corticosteroids. (cdc.gov)
  • Infectious - Human immunodeficiency virus (HIV) infection. (medscape.com)
  • The project, funded by the European Research Council , adapted magnetic resonance imaging (MRI) to non-invasively assess, in a single examination, the microstructure of both bone marrow and adipose tissue , comprised mainly of fat cells. (europa.eu)
  • Through bone marrow biopsy, acute myelogenous leukemia (AML) with maturation (FAB-M2) is diagnosed, and myelodysplasia (MDS) is also noted. (cdc.gov)
  • Risk factors for common types of non-Hodgkin lymphomas include autoimmune diseases, HIV/AIDS, infection with human T-lymphotropic virus, eating a large amount of meat and fat, immunosuppressant medications, and some pesticides.Diagnosis, if enlarged lymph nodes are present, is usually by lymph node biopsy. (geni.com)
  • Carcinogenesis consists essentially of several molecular alterations triggered by exposure to an agent or human carcinogen. (cdc.gov)
  • In 2011, the International Agency for Research on Cancer (IARC) reviewed the published literature and categorized RFR as a "possible" (Group 2B) human carcinogen. (stopumts.nl)
  • Chlorambucil is a carcinogen in humans. (nih.gov)
  • After strong chemotherapy or radiation therapy is used to destroy cancerous blood cells, the patient's blood-forming system is replaced with stem cells from a donor. (nutraingredients.com)
  • It is used in radiation therapy machines and other medical equipment. (thehindu.com)
  • This limits gene therapy to conditions affecting tissues like the blood or bone marrow that can be removed, treated and returned to the patient. (health.am)
  • The study, which appears in the early online edition of the Proceedings of the National Academy of Sciences (PNAS), found that mice lost 85 percent of their hair if they received radiation therapy in the morning, compared to a 17 percent loss when treatment occurred in the evening. (scienceblog.com)
  • These findings are particularly exciting because they present a significant step towards developing new radiation therapy protocols that include minimizing negative side effects on normal tissues, such as hair or bone marrow, while maintaining the desired effects on cancer cells," says Maksim Plikus, assistant professor of developmental and cell biology at UCI and the study's first author. (scienceblog.com)
  • The scientists can't say their findings will directly translate to human cancer therapy because they haven't yet studied that possibility. (scienceblog.com)
  • Over half of cancer patients undergo radiation therapy (RT). (nature.com)
  • Treatment may involve one or more of the following: chemotherapy, radiation therapy, targeted therapy, and surgery. (geni.com)
  • To test the effectiveness and safety of Optune® given concomitantly with radiation therapy (RT) and temozolomide (TMZ) in newly diagnosed GBM patients, compared to radiation therapy and temozolomide alone. (stanford.edu)
  • Given the poor prognosis of all patients with DIPG, patients may enroll at any point in their disease course provided they have received standard radiation therapy (also defined below) and meet all other eligibility requirements. (childrenshospital.org)
  • Standard radiation therapy is defined, for this study, as 54-60 Gy standard focal (photon or proton) radiation therapy, administered over 6 weeks (+/- 10 days). (childrenshospital.org)
  • Patients who receive standard radiation therapy with concurrent chemotherapy may be eligible as long as other criteria are met. (childrenshospital.org)
  • Patients must have received their last fraction of radiation therapy at least 2 weeks prior to treatment initiation. (childrenshospital.org)
  • It is generally divided into three types: bone marrow, gastrointestinal, and neurovascular syndrome, with bone marrow syndrome occurring at 0.7 to 10 Gy, and neurovascular syndrome occurring at doses that exceed 50 Gy. (wikipedia.org)
  • Each syndrome requires that the tissue showing the syndrome itself be exposed (e.g., gastrointestinal syndrome is not seen if the stomach and intestines are not exposed to radiation). (wikipedia.org)
  • Moreover, DNA damage is responsible for many of the toxicities incurred in treatment, including bone marrow suppression, hair loss, and gastrointestinal toxicites. (the-scientist.com)
  • In humans, they may colonize the pharynx, skin, and gastrointestinal and female genital tracts ( 2 ). (cdc.gov)
  • ARS differs from chronic radiation syndrome, which occurs following prolonged exposures to relatively low doses of radiation. (wikipedia.org)
  • In tests on animals, the substance, which mimics a hormone found in the body and prevents cell death and inflammation, was found to protect against lethal doses of radiation, as well as to speed up wound healing, reduce brain, kidney and heart injuries from trauma or disease, and even improve learning. (dotmed.com)
  • A person who has absorbed very large doses of radiation has little chance of recovery. (nocamels.com)
  • Simulation of radiation dose distribution in human organs and tissues is possible by tissue equivalent materials. (hindawi.com)
  • ICRU report 44 [ 1 ] describes various types of tissue substitutes for human organs and tissues. (hindawi.com)
  • Vice versa 3D bioprinted tissues could be used to study pathophysiological biological phenomena, when exposed to µg and cosmic radiation that will be useful on Earth to understand ageing conditioning of tissues, and in space for the crew of deep space manned missions. (selectbiosciences.com)
  • In addition to its immunotherapeutic activity, entolimod is among the most powerful experimental radiation countermeasures and shows efficacy in rodents and non-human primates as a prophylactic (radioprotection) and treatment (radiomitigation) modality for normal tissues but importantly not tumors. (roswellpark.org)
  • Scientists know for certain that other organs, such as the liver, use a circadian clock, and they suspect that all human tissue is similarly regulated, although the clocks may be timed differently. (scienceblog.com)
  • With the expansion of genetic modification, scientists are able to modify animal organs to decrease the chance of rejection within the human host. (grunge.com)
  • Several possible mechanisms were considered for the induction of human leukemia, such as clastogenic damage to circulatory stem cells. (who.int)
  • The Working Group was not aware of any good rodent models that simulate the occurrence of acute myeloid leukemia in humans. (who.int)
  • Therefore, on the basis of the data available at this time, it was not possible to identify a mechanism for the induction of myeloid leukemia in humans. (who.int)
  • The presence of modifiable factors, such as alcohol, biological agents, radiation, etc., and nonmodifiable (aka, genetic predisposition) factors, acting individually or in diverse combinations, can determine a person's risk of developing one form of cancer of another. (cdc.gov)
  • The FDA, an agency within the U.S. Department of Health and Human Services, protects the public health by assuring the safety, effectiveness, and security of human and veterinary drugs, vaccines and other biological products for human use, and medical devices. (fda.gov)
  • During the last decades, it has been shown that several biological systems including human cells, fungi, yeasts, bacteria, diatoms, algae, and plants can convert inorganic metal ions into metal NPs through reducing capacities. (degruyter.com)
  • Mouse and non- human primate models showed that serum miRNAs may be used to predict the biological impact of radiation doses. (bvsalud.org)
  • When exposed to high doses of ionizing radiation -- such as from a nuclear bomb blast -- fast-reproducing cells in the gut, bone marrow, and lungs can be destroyed, which can in turn lead to internal bleeding, a depressed immune system and death over the following days or even weeks. (dotmed.com)
  • Radiation poisoning, or Hematopoietic Acute Radiation Syndrome (H-ARS), is a deadly disease that can result from nuclear disasters and radiation exposure, and may lead to life-threateningly low amounts of red and white blood cells and possible death. (nocamels.com)
  • The current time calls for us to accelerate the development and accessibility of radiation treatments, especially as geopolitical instability rises, and nuclear power plants face the threat of warfare," said Pluri CEO and President Yaky Yanay. (nocamels.com)
  • With the recent nuclear catastrophe happening in Japan as well as the probability that nuclear events will continue to be a part of our world, it's prudent to have good reference information as to how the body can be supported (using natural means) and protected should high radiation exposure become a reality. (radiationdangers.com)
  • Each of these can be researched individually on the Internet such as "bee pollen+nuclear radiation protection", etc. in order to find out how it is helpful/useful to the body. (radiationdangers.com)
  • The traditional diagnostic biomarker for osteoporosis is bone mineral density (BMD). (europa.eu)
  • Serum miRNA-based signature indicates radiation exposure and dose in humans: A multicenter diagnostic biomarker study. (bvsalud.org)
  • Individuals possessing human leukocyte antigen (HLA)-B12 are 3 times more likely to develop this disorder. (medscape.com)
  • equisimilis , the group C and G antigen was found much more commonly in human infections than group A (GAS) ( 11 ). (cdc.gov)
  • That leads to the destruction of the bone marrow, resulting in symptoms such as infection and internal bleeding. (ndtv.com)
  • Cardiovirus (type species, encephalomyocarditis virus) is a classic infection in mice, although it has been observed to cause disease in humans. (medscape.com)
  • A multidisciplinary team from Memorial Sloan Kettering, in New York, has shown how the gut microbiota directly shapes the makeup of the human immune system, specifically showing that the concentration of different types of immune cells in the blood change in relation to the presence of different bacterial strains in the gut. (nutraingredients.com)
  • It uses cells derived from the human placenta to help the bone marrow recover, which regenerates the cells in the blood that circulate throughout the body. (nocamels.com)
  • He added that C. sinensis also helps human bodies take up Vitamin C more effectively, creating more blood and making capillary blood vessels more resilient. (pacherbs.com)
  • Myelofibrosis is a disease in which the bone marrow (the spongy tissue inside the large bones) becomes dense and fibrous, and starts producing abnormal immature blood cells that replace the normal blood cells. (europa.eu)
  • They included androgens (male hormones), glucocorticoids (a type of steroid) and erythropoietin (a hormone that stimulates the production of red blood cells) to treat anaemia, and surgery or radiation to remove or shrink the enlarged spleen. (europa.eu)
  • Blood, urine, and bone marrow testing may also be useful in the diagnosis. (geni.com)
  • The consensus of researchers studying RILI is that ionizing radiation could induce damage to epithelial cells and endothelial cells, dysfunction of the blood-air barrier, and increase vascular permeability. (biomedcentral.com)
  • During the 1600s, humans tried to use literally anything as a blood transfusion. (grunge.com)
  • And considering that these were some of the options available, anyone who was getting transfusions of animal blood was comparatively getting the better end of the deal, short of actually having a human blood transfusion of the corresponding blood type. (grunge.com)
  • We conclude that serum miRNAs reflect radiation exposure and dose for humans undergoing TBI and may be used as functional biodosimeters for precise identification of people exposed to clinically significant radiation doses. (bvsalud.org)
  • "The scientific community had already accepted the idea that the gut microbiota was important for the health of the human immune system, but the data they used to make that assumption came from animal studies," ​says Joao Xavier, Sloan Kettering Institute systems biologist and co-senior author of the paper (together with former postdoc Jonas Schluter, who is now an assistant professor at NYU Langone Health). (nutraingredients.com)
  • ARS is an illness that occurs following a high dose of radiation exposure, leading to severe damage to the bone marrow and the immune system. (nwahomepage.com)
  • These foods and food substances will enhance the immune system and protect against the dangerous side effects of radiation. (radiationdangers.com)
  • Stem cells from a donor, called a graft , are then infused to replace the destroyed cells, produce new marrow, and rebuild the recipient's immune system. (cancer.gov)
  • Winners of contracts include Neumedicines Inc., which got a $17 million award to study recombinant human interleukin-12 (rhuIL-12). (dotmed.com)
  • Nivestym (filgrastim-aafi) is a recombinant human granulocyte colony-stimulating factor biosimilar to Neupogen indicated for the treatment of neutropenia associated with chemotherapy and related conditions. (drugs.com)
  • A genome-wide screen in Saccharomyces cerevisiae identified LSM1 as a new gene affecting sensitivity to ultraviolet (UV) radiation. (bioone.org)
  • We report here that Ptch +/- mice develop primordial follicular neoplasms resembling human trichoblastomas, and that exposure to ultraviolet radiation or ionizing radiation results in an increase in the number and size of these tumors and a shift in their histologic features so that they more closely resemble human basal cell carcinoma. (nature.com)
  • The Ptch mutant mice provide the first mouse model, to our knowledge, of ultraviolet and ionizing radiation-induced basal cell carcinoma-like tumors, and also demonstrate that Ptch inactivation and hedgehog target gene activation are essential for basal cell carcinoma tumorigenesis. (nature.com)
  • Exposure to ultraviolet radiation (UVr) contained in sunlight is a major cause of skin illness such as sunburn, aging and cancer. (intechopen.com)
  • In addition, three large-scale carcinogenicity studies in rodents exposed to levels of RFR that mimic lifetime human exposures have shown significantly increased rates of Schwannomas and malignant gliomas, as well as chromosomal DNA damage. (stopumts.nl)
  • Identifying and developing effective countermeasures to treat pathologies associated with acute radiation syndrome. (roswellpark.org)
  • Unveiling this novel TLR5-neutrophil-MMP-9 axis of radiomitigation has opened new opportunities for developing efficacious countermeasures to treat pathologies associated with ARS following scenarios of accidental radiation disasters or myeloablative chemotherapy in the case of cancer patients. (roswellpark.org)
  • The signs and symptoms of this form of radiation injury include nausea, vomiting, loss of appetite, and abdominal pain. (wikipedia.org)
  • These symptoms may occur at radiation doses as low as 0.35 grays (35 rad). (wikipedia.org)
  • A similar table and description of symptoms (given in rems, where 100 rem = 1 Sv), derived from data from the effects on humans subjected to the atomic bombings of Hiroshima and Nagasaki, the indigenous peoples of the Marshall Islands subjected to the Castle Bravo thermonuclear bomb, animal studies and lab experiment accidents, have been compiled by the U.S. Department of Defense. (wikipedia.org)
  • As a result of treatment with Inrebic, 36 patients experienced greater than or equal to a 50% reduction in myelofibrosis-related symptoms, such as night sweats, itching, abdominal discomfort, feeling full sooner than normal, pain under ribs on left side, and bone or muscle pain. (fda.gov)
  • Be mindful of evacuation routes and plans, as well as the symptoms of radiation exposure. (millonpeskin.com)
  • Formaldehyde is carcinogenic to humans (Group 1) . (who.int)
  • There is sufficient evidence in humans for the carcinogenicity of formaldehyde. (who.int)
  • Formaldehyde has been evaluated by IARC to be a known cause of human nasal cancer, based on epidemiological and toxicological evidence. (who.int)
  • Prior to today, there was one FDA-approved drug to treat patients with myelofibrosis, a rare bone marrow disorder. (fda.gov)
  • Dr. D. K. Sharma, medical superintendent, said "One of the four patients of radiation exposure admitted with us - Mr. Gaurav - was discharged in the morning after doctors saw improvement in his condition. (thehindu.com)
  • They are also translating their bone and bone marrow imaging techniques into clinical spine examinations, especially to assess fracture in patients with degenerative spine changes and bone metastases. (europa.eu)
  • Even though more localized dose delivery to patients with tumors via advanced radiation techniques can increase the survival rate and lessen radiation-related toxicity, the occurrence of radiation-induced lung injury (RILI) is still inevitable and limits dose escalation for thoracic radiotherapy [ 2 ]. (biomedcentral.com)
  • Clinical trials are a stage in medical research that tests the effectiveness of a treatment on human patients. (thepatientstory.com)
  • In normal wound healing, this inflammation response may subside and induce a vicious cycle of further inflammation once radiation pneumonitis happens, finally leading to the poor prognosis. (biomedcentral.com)
  • based RxBio Inc. nabbed a two-year, $15 million contract to study Rx100, a small molecule-drug which might be able to prevent cells in the gut from dying if administered up to three days after radiation exposure. (dotmed.com)
  • The marrow fat was shown to differ depending on the age and sex of subjects, unlike the bone, suggesting complex pathophysiological influences on fat cells. (europa.eu)
  • Under the FatVirtualBiopsy project, the team are currently developing a proof of concept that translates lipid droplet size measurements into a non-invasive tool to measure the size of human fat cells in vivo. (europa.eu)
  • it's the accumulation of radiation that can be damaging to our cells. (pacherbs.com)
  • Because we live in a world with radiation around us 24/7 adding these foods and supplements to your diet at any time will help your cells cope with the onslaught of radiation that we live with everyday. (pacherbs.com)
  • This is a complex procedure where the patient receives stem cells from a matched donor to help restore the bone marrow. (europa.eu)
  • When lung tissue is irradiated by x-ray cells are injured by the direct or indirect action of radiation. (biomedcentral.com)
  • The mechanisms of radiation-induced lung injury (RILI) and the mechanisms by which mesenchymal stem cells (MSCs) alleviate it. (biomedcentral.com)
  • This study provides a detailed characterization of the dose-dependent impact of ionizing radiation on skin cells (45, 60, or 80 grays). (mdpi.com)
  • Graftskin was used to close full-thickness wound defects on the dorsum of 24 athymic mice, which lack effective T-cell immunity to reject the human cells. (medbc.com)
  • Bone marrow aspirate demonstrating plasma cells of multiple myeloma. (medscape.com)
  • However, the radiation dose in lunar orbit from the October 2021 solar event, as measured by Nasa's LRO, was only about 31 milligray and was not dangerous for astronauts. (ndtv.com)
  • For long-term space exploratory missions and extra-terrestrial human settlements, e. g. on Moon or Mars, the astronauts must be able to treat health problems on site as a fast return to Earth is impossible. (selectbiosciences.com)
  • Three more persons - Ram Kalap, Himanshu Jain and Ramji Yadav - who were also exposed to radiation continue to receive treatment at the institute. (thehindu.com)
  • The FDA's Orphan Drug Designation is aimed at advancing treatments for rare diseases, including Acute Radiation Syndrome (ARS), which currently has limited treatment options. (nwahomepage.com)
  • ROCKVILLE, Md , Nov. 20, 2023 /PRNewswire/ -- NeoImmuneTech, Inc. (NIT or "NeoImmuneTech"), a clinical-stage T cell-focused biopharmaceutical company, today announced that the U.S. Food and Drug Administration (FDA) has granted Orphan Drug Designation (ODD) for their investigational drug NT-I7 (efineptakin alfa) (rhIL-7-hyFc) for the treatment of Acute Radiation Syndrome (ARS). (nwahomepage.com)
  • An Israeli biotechnology company will collaborate with the US government to help develop its new treatment for radiation poisoning. (nocamels.com)
  • In studies, the treatment increased the survival rates of animals exposed to radiation from 29 percent in the control group to 97 percent in the treated group. (nocamels.com)
  • Phase I trials are not testing the effectiveness of a treatment - they are primarily focused on how safe the treatment is for humans. (thepatientstory.com)
  • Acute Radiation Syndrome (ARS) is an acute illness caused by irradiation of the entire body by a high dose of penetrating radiation in a very short period of time (typically a matter of minutes or less). (nwahomepage.com)
  • We hypothesized that these results can be translated to humans treated with total body irradiation (TBI), and that miRNAs may be used as clinically feasible biodosimeters. (bvsalud.org)
  • Radiation-induced impairments in hippocampal function may be more pronounced in female Apoe −/− mice and more pronounced in mice irradiated and tested cognitively later in life. (bioone.org)
  • While we don't yet know if human hair follows that same clock we found in mice hair, it is true that facial hair in men grows during the day, resulting in the proverbial 5 o'clock shadow. (scienceblog.com)
  • [ 9 ] Certain strains of this virus are associated with the development of diabetes in certain strains of mice and are used as a model for virus-associated insulin-requiring diabetes in humans. (medscape.com)
  • Differential expression results were consistent with previous studies in mice and non- human primates . (bvsalud.org)
  • miRNAs with detectable expression in this and two prior animal sets allowed for distinction of the irradiated from non-irradiated samples in mice , macaques and humans , validating the miRNAs as radiation -responsive through evolutionarily conserved transcriptional regulation mechanisms. (bvsalud.org)
  • Based on the accumulated evidence, we recommend that IARC re-evaluate its 2011 classification of the human carcinogenicity of RFR, and that WHO complete a systematic review of multiple other health effects such as sperm damage. (stopumts.nl)
  • Discovering that mouse hair has a circadian clock - a 24-hour cycle of growth followed by restorative repair - researchers suspect that hair loss in humans from toxic cancer radiotherapy and chemotherapy might be minimized if these treatments are given late in the day. (scienceblog.com)
  • In addition, reishi and cordyceps mushrooms can protect bone marrow from toxic assaults, and antioxidants can help the body defend itself from radiation damage. (pacherbs.com)
  • Each radioactive element, including strontium, constantly gives off radiation, and this process changes it into an isotope of another element or a different isotope of the same element. (cdc.gov)
  • The reduction of radioactive particles in bone uptake, measured in the femur, reached as high as 80 percent, with little interference with calcium absorption. (radiationdangers.com)
  • The Atomic Energy Commission recommends for maximum protection against radioactive poisoning for humans, taking a minimum of 2 to 3 ounces of sea vegetables a week or 10 grams (two tablespoons) a day of sodium alginate supplements. (radiationdangers.com)
  • The mouse basal cell carcinomas and trichoblastoma-like tumors resemble human basal cell carcinomas in their loss of normal hemidesmosomal components, presence of p53 mutations, frequent loss of the normal remaining Ptch allele, and activation of hedgehog target gene transcription. (nature.com)
  • Since radiotherapy is widely used in managing thoracic tumors, physicians have begun to realize that radiation-induced lung injury (RILI) seriously limits the effects of radiotherapy. (biomedcentral.com)
  • Biomedical Advanced Research and Development Authority, or BARDA, a division of the Department of Health and Human Services, announced the roughly $60 million in funding in a series of releases Wednesday and Thursday. (dotmed.com)
  • Compared with an adult male, a cell phone held against the head of a child exposes deeper brain structures to greater radiation doses per unit volume, and the young, thin skull's bone marrow absorbs a roughly 10-fold higher local dose. (stopumts.nl)
  • To investigate the potential role of Lsm1p in response to UV radiation, we constructed double mutant strains in which LSM1 was deleted in combination with a representative gene from each of three known yeast DNA repair pathways. (bioone.org)
  • The collagen lattice containing fibroblasts is designed as a living dermal template, and the overlying human keratinocytes form the epidermal component of this composite skin replacement. (medbc.com)
  • In addition to the major human enteroviral pathogens (poliovirus, enterovirus, coxsackievirus , echovirus), rhinoviruses (approximately 105 serotypes), the human hepatitis A virus (HAV), and several parechoviruses, Picornaviridae contains several other genera of viruses that infect nonhuman vertebrate hosts. (medscape.com)
  • Measurements of high-level radiation events by robotic missions are critical to prepare for long-duration crewed missions. (ndtv.com)
  • a separate model differentiating between high and low radiation dose achieved AUC of 0.85 (95%CI 0.74-0.96). (bvsalud.org)
  • Our results show that lsm1 Δ increases the UV-radiation sensitivity of the rad1 Δ and rad51 Δ mutants, but not the rad18 Δ mutant, placing LSM1 within the post-replication repair/damage tolerance pathway (PRR). (bioone.org)
  • Together, these results suggest that Lsm1p may confer protection against UV-radiation damage by protecting the 3′ ends of mRNAs from exosome-dependent 3′ to 5′ degradation as part of a novel RAD5- mediated, PCNA-K164 ubiquitylation-independent subpathway of PRR. (bioone.org)
  • Agents from sunlight to chemicals, ionizing radiation, and oxygen radicals can either directly damage bases or break the phosphodiester backbone on which the bases reside. (the-scientist.com)
  • From the perspective of cancer, DNA damage causes the disease, but it is also used to treat the disease via radiation and many chemotherapeutic agents. (the-scientist.com)
  • Also in this year, the first known case of human HIV disease was identified in the Belgian Congo. (bcmj.org)
  • This reduces the possibility of getting Jod-Basedow syndrome, a hyperthyroid disease one can acquire after taking potassium iodide to combat radiation poisoning. (pacherbs.com)
  • There's also the risk of animal-to-human disease transmission, known as zoonosis, which may lead to those with a xenotransplant being subjected to restrictions or temporary detentions. (grunge.com)
  • Interventions move on to a Phase II trial when they are determined to be safe in Phase I. The goal of a Phase II clinical trial is to see if the drug is effective at treating the target disease in humans. (thepatientstory.com)
  • Cindy Hinton is a health scientist in the disability and health branch in the division of human development and disability at the Centers for Disease Control and Prevention. (cdc.gov)
  • Xenotransplants involve putting the well-being of a human above the well-being of an animal, which involves not only the death of the animal but the lifestyle it must be raised in to minimize "the risk of acquired infections. (grunge.com)