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  • pathway
  • a mutant Rad17 pathway is associated with a general deregulation of DNA repair, which seems to be correlated with a deficiency in non-homologous double strand break repair. (antibodies-online.com)
  • The Rad17 C-terminal tail is a molecular switch that regulates the 9-1-1 interaction and the ATR pathway. (antibodies-online.com)
  • Data indicate that regulation of Rad17 turnover is through the Cdh1/anaphase-promoting complex pathway in breast cancer cells. (nih.gov)
  • human
  • Overexpression of Rad17 has been associated with human breast and colon cancers [ PMID: 10232579 , PMID: 11555598 ]. (ebi.ac.uk)
  • Synthetic peptide made to a N-terminal region of human RAD17. (genetex.com)
  • Western blot analysis of human RAD17 in heart lysate with anti-huRAD17 (GTX30134) at a 1:500 dilution. (genetex.com)
  • Antigen: Peptide corresponding to aa 2-15 of human RAD17. (qedbio.com)