• Progress has been made to better understand about effect of regulons (AREB/ABF, DREB, MYB, and NAC) under abiotic stresses and a number of regulons reported for stress responsive and used as a better transgenic tool of Arabidopsis and Rice. (scielo.br)
  • Progresso foi feito para entender melhor sobre o efeito dos regulons (AREB / ABF, DREB, MYB e NAC) sob estresses abióticos e uma série de regulons relatados como responsivos ao estresse e usados ​​como uma melhor ferramenta transgênica de Arabidopsis e Rice. (scielo.br)
  • During plant growth and development, MYB transcription factors play an important role in responding to abiotic stresses and regulating the synthesis of secondary metabolites. (biomedcentral.com)
  • Myb genes are part of a large gene family of transcription factors found in animals and plants. (wikipedia.org)
  • The Myb gene family is named after the eponymous gene in Avian myeloblastosis virus. (wikipedia.org)
  • Like the viral version, this gene is an oncogene, and rearrangements of the gene (often involving deletion in the C-terminal domain) causes cancer. (wikipedia.org)
  • In maize, phlobaphenes are synthesized in the flavonoids synthetic pathway from polymerisation of flavan-4-ols which encodes an R2R3 myb-like transcriptional activator of the A1 gene encoding for the dihydroflavonol 4-reductase (reducing dihydroflavonols into flavan-4-ols) while another gene (Suppressor of Pericarp Pigmentation 1 or SPP1) acts as a suppressor. (wikipedia.org)
  • The maize P gene encodes a Myb homolog that recognizes the sequence CCWACC, in sharp contrast with the YAACGG bound by vertebrate Myb proteins. (wikipedia.org)
  • In sorghum, the corresponding yellow seed 1 gene (y1) also encodes a R2R3 type of Myb domain protein that regulates the expression of chalcone synthase, chalcone isomerase and dihydroflavonol reductase genes required for the biosynthesis of 3-deoxyflavonoids. (wikipedia.org)
  • By this technique, we have recognized 240 prevalent considerable gene expression adjustments in at least two gene lists, and among these 9 had been popular in all four comparisons, such as, phenylethanolamine N methyltransferase, ret proto oncogene, Src homology 2 do key containing transforming protein one. (tcr-signal.com)
  • Myb proto-oncogene protein is a member of the MYB (myeloblastosis) family of transcription factors. (wikipedia.org)
  • The present findings provide data resources for the subsequent study of the functions of MYB transcription factor family members in ginseng, and provide an experimental basis for the anti-salt functions of MYB transcription factors in Panax ginseng . (biomedcentral.com)
  • Ruby is a MYB transcriptional activator of genes that produce anthocyanin in citrus fruits. (wikipedia.org)
  • Plants contain a MYB-protein subfamily that is characterised by the R2R3-type MYB domain. (wikipedia.org)
  • Members of the extended SANT/Myb family also include the SANT domain and other similar all-helical homeobox-like domains. (wikipedia.org)
  • Compared to the normal animal cellular Myb (c-myb), v-myb contains deletions in the C-terminal regulatory domain, leading to aberrant activation of other oncogenes. (wikipedia.org)
  • The protein contains three domains, an N-terminal DNA-binding domain, a central transcriptional activation domain and a C-terminal domain involved in transcriptional repression. (wikipedia.org)
  • MYB factors represent a family of proteins that include the conserved MYB DNA-binding domain. (wikipedia.org)
  • The MYB structural domain usually consists of one to three incomplete repeats of approximately 52 amino acid residues in a helix-turn-helix conformation inserted into the main DNA groove [ 11 ]. (biomedcentral.com)
  • However, there are relatively few reports on the MYB transcription factor family in Panax ginseng . (biomedcentral.com)
  • A MYB-related transcription factor (MIXTA) that controls development of conical cell form is expressed only in the inner epidermis of Antirrhinum petals. (biologists.com)
  • Moreover, vitamin B12 increased the ratio of microtubule-associated protein 1 light chain 3 beta to microtubule-associated protein 1 light chain 3 alpha (LC3-II/LC3-I), while decreasing the amount of sequestosome 1 (p62) and inhibiting the phosphorylation of p70 ribosomal protein S6 kinase (p70S6K) under both normal- and high-glucose conditions. (bvsalud.org)
  • The maize P gene encodes a Myb homolog that recognizes the sequence CCWACC, in sharp contrast with the YAACGG bound by vertebrate Myb proteins. (wikipedia.org)
  • The vertebrate Myb transcription factors comprise a small family of important regulatory proteins. (123dok.net)
  • Our results allow for a more thorough functional characterization of the guava MYB family genes and open the door to additional research into one essential MYB transcription factor family of genes and its involvement in the growth and ripening of guava fruit. (springeropen.com)
  • progres-sion through the cell cycle is highly modulated through a regulatory axis containing the E2F transcription factor and retinoblastoma tumour suppressor protein families. (123dok.net)
  • One of the genes regulated through this mechanism en-codes the B-Myb transcription factor, which has been shown to be critically required for early embryonal de-velopment in the mouse. (123dok.net)
  • The protein contains three domains, an N-terminal DNA-binding domain, a central transcriptional activation domain and a C-terminal domain involved in transcriptional repression. (wikipedia.org)
  • In maize, phlobaphenes are synthesized in the flavonoids synthetic pathway from polymerisation of flavan-4-ols which encodes an R2R3 myb-like transcriptional activator of the A1 gene encoding for the dihydroflavonol 4-reductase (reducing dihydroflavonols into flavan-4-ols) while another gene (Suppressor of Pericarp Pigmentation 1 or SPP1) acts as a suppressor. (wikipedia.org)
  • Ruby is a MYB transcriptional activator of genes that produce anthocyanin in citrus fruits. (wikipedia.org)
  • We discuss in this review re-cent findings suggesting that B-Myb is a multifunctional protein that has, in addition to its transcriptional proper-ties, the ability to interact directly with other regulators of the cell cycle. (123dok.net)
  • A set of highly conserved tryptophan (W) residues found in the MYB domain is involved in sequence-specific DNA binding [ 6 ]. (springeropen.com)
  • Compared to the normal animal cellular Myb (c-myb), v-myb contains deletions in the C-terminal regulatory domain, leading to aberrant activation of other oncogenes. (wikipedia.org)
  • In sorghum, the corresponding yellow seed 1 gene (y1) also encodes a R2R3 type of Myb domain protein that regulates the expression of chalcone synthase, chalcone isomerase and dihydroflavonol reductase genes required for the biosynthesis of 3-deoxyflavonoids. (wikipedia.org)
  • MYB transcription factors are made up of two unique regions: an N-terminal conserved MYB DNA binding domain and a C-terminal variable modulator region that regulates the activities of proteins. (springeropen.com)
  • The fact that three different Myb proteins have been found in higher vertebrates suggests that they have spe-cific and distinct functions. (123dok.net)
  • Additionally, the expression patterns of the particular MYBs showed that MYB may be involved in the control of wilt, fruit ripening, seed development, and root development. (springeropen.com)
  • Consistent with this expression pattern, male mice lacking A-Myb are infer-tile because of a block in spermatogenesis, and A-myb null females have underdeveloped breast tissue after pregnancy [19]. (123dok.net)
  • Consistent with this, B-myb knock-out mice die at a very early stage of development (E4.5 - E6.5), and a requirement for B-Myb in inner cell mass formation is indicated by the se-verely impaired proliferation of these pluripotent cells when blastocysts were explanted and cultured in vitro [24]. (123dok.net)
  • The protein expression of NHE3, NKCC1 and eNaC were also significant increase in the intestine of CKO-HS mice. (bvsalud.org)
  • This study's goal was to assess the expression of MYB in guava fruit pulp, roots, and seeds to predict its function by in silico analysis of the guava root transcriptome data. (springeropen.com)
  • The expression of six different MYB TFs was examined using semi-quantitative RT-PCR in "Shweta" pulp (white colour pulp), "Lalit" pulp (red color pulp), "Lalit" root, and "Lalit" seed. (springeropen.com)
  • before either c-myb or A-myb, and its expression is re-stricted to zones of cell proliferation [23]. (123dok.net)
  • The fact that B-myb expression is strongly associated with proliferating cells of all lineages suggests that this gene may play an important and general role during the cell cycle. (123dok.net)
  • From the analyses, it was found that R2-MYB and R3-MYB domains are conserved in all known guava MYB proteins. (springeropen.com)
  • In humans, it includes Myb proto-oncogene like 1 and Myb-related protein B in addition to MYB proper. (wikipedia.org)
  • Myb is substantially enhanced in S phase through modi-fication by cyclin A/cdk2, and the evidence points squarely to the major role being played by B-Myb during this phase of the cell cycle. (123dok.net)
  • c-Myb is expressed at high levels in most haematopoietic precursor cells and plays a crucial role in blood cell development [1, 15, 16]. (123dok.net)
  • HSYA increased the protein levels of SLC7A11, HIF-1α, and GPX4 and mitigated erastin- or HIF-1α siRNA-induced damage in H9C2 cells. (bvsalud.org)