Quantitative trait analysis. Medical search. Frequent questions

Quantitative trait loci analysis of glucosinolate, sugar, and organic acid concentrations in Eruca vesicaria subsp. (reading.ac.uk)
Quantitative trait loci analysis of contextual fear conditioning in mice. (bvsalud.org)

Wright and others formalized population genetics theory that had been worked out over the preceding 30 years explaining how such traits can be inherited and create stably breeding populations with unique characteristics. (wikipedia.org)
Quantitative trait genetics today leverages Wright's observations about the statistical relationship between genotype and phenotype in families and populations to understand how certain genetic features can affect variation in natural and derived populations. (wikipedia.org)
In this paper, rather than focusing on genes as an organising concept around which historical considerations of theory and practice in genetics are elucidated, we place genetic markers at the heart of our analysis. (web.app)
It is anticipated that insight in the genetics of intermediate phenotypes will provide additional insight into the genetics of complex traits. (ox.ac.uk)
Jackson Lab researchers mentor students in the latest genetics research techniques, including Quantitative Trait Loci (QTL) analysis, a statistical process used to pinpoint the location of unknown genes. (concord.org)
Databases and computer-based analysis techniques have changed the face of much of biology research, especially genetics. (concord.org)
We and 3 with more than 1 aposthia male: fam- think that the person with aposthia trait is a ily DG-01 had 4 living cases, family DG-02 suitable model to study the importance and had 2 living and 1 dead case and family DG- genetics of the prepuce. (who.int)

Linkage studies have identified several quantitative trait loci (QTLs) for RD. The QTL on chromosome 6p21.3 has been independently replicated by several groups and spans a 16.4-Mb (13.8 cM) interval from D6S109 to D6S291. (nih.gov)
A total of 39 QTLs for growth habit-related traits was detected on 10 chromosomes explaining 4.55-27.74% of the phenotypic variance, in which 6 QTLs were for lateral branch angle, 8 QTLs were for extent radius, 7 QTLs were for the index of plant type, 11 QTLs were for main stem height, and 7 QTLs were for lateral branch length. (frontiersin.org)
QTLs are mapped by identifying which molecular markers (such as SNPs or AFLPs) correlate with an observed trait. (wikipedia.org)
The number of QTLs which explain variation in the phenotypic trait indicates the genetic architecture of a trait. (wikipedia.org)
Typically, QTLs underlie continuous traits (those traits which vary continuously, e.g. height) as opposed to discrete traits (traits that have two or several character values, e.g. red hair in humans, a recessive trait, or smooth vs. wrinkled peas used by Mendel in his experiments). (wikipedia.org)
Consequently, many QTLs are associated with a single trait. (wikipedia.org)
Another use of QTLs is to identify candidate genes underlying a trait. (wikipedia.org)
Heritable differences in transcribed RNA levels can be mapped as quantitative trait loci (QTLs). (biomedcentral.com)

Quantitative trait locus analysis of the development of pulmonary tolerance to inhaled zinc oxide. (cdc.gov)
Identification of genetic loci affecting the severity of symptoms of Hirschsprung disease in rats carrying Ednrbsl mutations by quantitative trait locus analysis. (cdc.gov)

One possible way toward finding the underlying genes is to map intermediary molecular phenotypes, such as gene expression traits. (scilifelab.se)
Overlaps between egg loci and expression loci, and trait-gene expression correlations identify 29 candidates from bone and five from hypothalamus. (scilifelab.se)
Examples of 2-omics analyses include expression quantitative trait locus eQTL (Franke & Jansen, 2009) and methylation quantitative trait locus meQTL (Smith, Kilaru, Kocak, Almli, & Mercer, 2014) that, respectively, assess the influence of genetic and epigenetic markers on gene expression. (researchgate.net)
These evidences are often based on the derivation of standard measures of association, linking (epi-)genetic markers to gene expression combined with gene expression analysis (Wagner, Busche, Ge, Kwan, & Pastinen, 2014). (researchgate.net)
We applied our INQUSIT pipeline for prioritizing genes as targets of those potentially causal variants, using gene expression (expression quantitative trait loci), chromatin interaction and functional annotations. (lu.se)

Linkage was assessed by using five quantitative phenotypes, including a composite measure of reading performance and four component phenotypes. (nih.gov)
When probands were selected for severe scores, single- and multi-point analyses showed significant linkage with all five phenotypes, converging over an interval of ~3.24 Mb spanning D6S1597 to D6S1571. (nih.gov)
29 Feb 2008 Complex phenotypes, including quantitative traits and common observations of variance due to these components in analysis of data. (web.app)
The analysis of individual marks indicated the association of 51 markers to phenotypes. (usp.br)
The identification of causal or predictive variants/genes/mechanisms for disease-associated traits is characterized by 'complex' networks of molecular phenotypes. (researchgate.net)
Longitudinally measured phenotypes are important for exploring genetic and environmental factors that affect complex traits over time. (intlpress.com)

The two types of approaches lead to predictions of genomic values for quantitative traits. (web.app)
We then combined the genomic confidence intervals of these loci with expression quantitative trait loci from bone and hypothalamus in the same intercross. (scilifelab.se)
Therefore, the causal genes and pathways are still not well known and additional genomic functional analyses are required to elucidate the biological mechanism between genetic variants and the risk of cervical cancer [ 12 , 13 ]. (jcancer.org)
These regions were explored by combining association analysis with in silico genomic feature annotations. (lu.se)

Out of 12 genes in the linkage interval, ten clustered within ~680 kb and were selected for association analysis based on central nervous system expression and putative function. (nih.gov)
Marker associations were detected in five of the ten genes, results that were corroborated by our haplotype TDT analysis. (nih.gov)
Analysis of the co-localized genome region has shown that the putative genes are involved in light and hormones and will facilitate peanut growth habit molecular breeding and study of peanut domestication. (frontiersin.org)
This is often an early step in identifying the actual genes that cause the trait variation. (wikipedia.org)
A quantitative trait locus (QTL) is a region of DNA which is associated with a particular phenotypic trait, which varies in degree and which can be attributed to polygenic effects, i.e., the product of two or more genes, and their environment. (wikipedia.org)
Moreover, a single phenotypic trait is usually determined by many genes. (wikipedia.org)
Quantitative Trait Locus and Genetical Genomics Analysis Identifies Putatively Causal Genes for Fecundity and Brooding in the Chicken. (scilifelab.se)
We set out to map candidate quantitative trait genes for egg fecundity in the chicken by combining quantitative trait locus mapping in an advanced intercross of wild by domestic chickens with expression quantitative trait locus mapping in the same birds. (scilifelab.se)
The candidate quantitative trait genes include fibroblast growth factor 1, and mitochondrial ribosomal proteins L42 and L32. (scilifelab.se)
In summary, we found putative quantitative trait genes for egg traits in the chicken that may have been affected by regulatory variants under chicken domestication. (scilifelab.se)
These represent, to the best of our knowledge, some of the first candidate genes identified by genome-wide mapping for life history traits in an avian species. (scilifelab.se)
Here, we set out a GWAS for metabolite quantitative traits in serum, followed by exome sequence analysis to zoom in on putative causal variants in the associated genes. (ox.ac.uk)
Based on physical vicinity and pathway analyses, candidate genes were screened for coding region variation using exome sequence data. (ox.ac.uk)
Exome sequence analysis identified potentially causal coding and regulatory variants located in the genes CPS1, KCNJ2 and PRODH, and revealed allelic heterogeneity for CPS1 and PRODH. (ox.ac.uk)
In-depth biological analysis of connected genes in ANDnet and XORnet revealed genes that are related to energy metabolism, cell cycle control (AATF), immune system response, and several cancer types. (researchgate.net)
These are traits that are complex, continuous and regulated by a group of genes interacting with each other and the environment. (jax.org)
In the past two decades, QTL analyses have identified well over 2000 QTL associated with such diseases, 1,2,3 and the genes underlying these QTL are being identified at a faster pace than ever. (jax.org)
These results indicate that the differences in these two traits are either pleiotropic effects of a single gene or the effect of closely linked genes. (cas.cz)
We have also attempted to verify a series of differentially expressed candidate susceptibility genes to lung tumours in our previous microarray analysis with semiquantitative reverse transcriptase PCR (RT-PCR). (bmj.com)
This graph shows the probability that a certain area on a chromosome (displayed below the graph) contains genes related to the trait being studied. (concord.org)
Using the protein-protein interaction analysis we observed strong interactions between the proteins produced by genes that are associated with cervical cancer. (jcancer.org)
Together, our results show that individuals in the MOD cluster show aberrant RNA expression of genes that have a suggested causal role on multiple diabetes-relevant traits. (lu.se)

Cluster analyses were used to distinguish the two putative genotypes, the least affected with NIHL (+/Ahl) and most affected with PTS (Ahl/Ahl). (cdc.gov)

He defined the ideotype as plants that have comprehensive agronomic traits known to influence photosynthesis, growth habit, and grain yield (in cereals). (frontiersin.org)

Castle's was perhaps the first attempt made in the scientific literature to direct evolution by artificial selection of a trait with continuous underlying variation, however the practice had previously been widely employed in the development of agriculture to obtain livestock or plants with favorable features from populations that show quantitative variation in traits like body size or grain yield. (wikipedia.org)
19 Aug 2003 populations for quantitative traits is phenotypic selection. (web.app)
The QTL mapping was performed using composite interval and a special strategy for segregating F1 populations, identified 26 regions associated with QTL for the five traits, 16 of them related to LA, CA and NEA. (usp.br)
Inbreeding depression is often measured in fitness-related traits of life history (e.g. fecundity, survival, morphological measurements) and often only in captive populations ( Hedrick and Kalinowski 2000 ). (biorxiv.org)
2011. Intra-population comparison of vegetative and floral trait heritabilities estimated from molecular markers in wild Aquilegia populations . (sussex.ac.uk)

In this study, we performed sib-pair linkage analyses with Haseman-Elston and DeFries-Fulker methods to define more accurately the QTL interval. (nih.gov)
This analysis demonstrates the applicability of using martingale residuals as a quantitative trait in linkage analyses of diseases that depend on age of onset. (elsevierpure.com)

The method, which assumes underlying normal distributions, is a combination of maximum likelihood and moments methods and uses the statistics of the genetic marker genotype samples for the quantitative trait to estimate the recombination frequency between the two loci and the means and variances of the genotypes of the quantitative trait locus. (agri.gov.il)
For some traits, ranking of genotypes differed greatly between seasons and different QTL were identified. (massey.ac.nz)
In genetic studies, the variation in genotypes may not only affect different inheritance patterns in qualitative traits, but may also affect the age-at-onset as quantitative trait. (bepress.com)

We carried out an expression quantitative trait loci (eQTL) study of primary human osteoblasts (HOb) derived from 95 unrelated donors of Swedish origin, each represented by two independently derived primary lines to provide biological replication. (nih.gov)

The aims of quantitative trait loci detection is the potential use of these molecular markers to increase accuracy in predicting the genetic merit of breeding and its implementation in animal breeding schemes through marker-assisted selection. (cambridge.org)
Maximum likelihood techniques for the mapping and analysis of quantitative trait loci with the aid of genetic markers. (agri.gov.il)
The aims of this study were to develop a genetic linkage map of perennial ryegrass, identify quantitative trait loci (QTL) for herbage and seed production traits, and to identify DNA markers associated with QTL for use in marker-assisted selection (MAS). (massey.ac.nz)
A genetic linkage map spanning 582 centimorgans (cM) was constructed with EST-SSR (simple sequence repeat markers derived from expressed sequence tags) and used to identify QTL for herbage dry weight (DW) and seed yield per plant (SdYP), and their key component traits. (massey.ac.nz)
Marker-trait validation confirmed markers pps0495 and pps0698 identified by QTL analysis to be potentially useful for selecting for fast leaf appearance and long LL, respectively, in perennial ryegrass. (massey.ac.nz)
Breeding opportunities for crop improvement have been greatly expedited using molecular mapping program of DNA markers and quantitative trait loci (QTL). (usda.gov)

We used these residuals as quantitative traits in variance components linkage scans for the 50 replicates of the general population simulated data for chromosomes 6 and 7. (elsevierpure.com)
We account for differential sampling in the association analysis by inverse probability weighting (IPW) with standard survey methods for variance estimation and hypothesis testing. (biomedcentral.com)
A variance-covariance structure is constructed to model the measurement variation and correlations of the traits based on the theory of stochastic processes. (intlpress.com)

Methods We examined the association of autism traits with NF1, NS, CS and CFC, comparing affected probands with unaffected sibling controls and subjects with idiopathic ASDs using the qualitative Social Communication Questionnaire (SCQ) and the quantitative Social Responsiveness Scale (SRS). (bmj.com)
Results Each of the four major RASopathies showed evidence for increased qualitative and quantitative autism traits compared with sibling controls. (bmj.com)
A method of differentiating individuals based on the analysis of qualitative or quantitative biological traits or patterns. (bvsalud.org)

These results show that the average size of the quantitative trait loci effect was 1.6 phenotypic standard deviations for different traits and families. (cambridge.org)
Linkage distance between the two loci was 38 map units and the effect of the quantitative trait locus was 1.6 phenotypic standard deviation units. (agri.gov.il)
The method is not effective in distinguishing between complete and partial linkage in samples of only 500 individuals or for quantitative loci with effects less than a phenotypic standard deviation. (agri.gov.il)

In addition to a simple random sampling design, we consider extreme-phenotype designs that are of increasing interest in genetic association analysis of QTs, especially in studies concerned with the detection of rare genetic variants. (biomedcentral.com)
Therefore, the objective of this study was to evaluate two analytical techniques based on fast volatile analysis on their performance for monitoring evolution and early detection of B. cinerea infections in strawberry. (who.int)

We find that PM20D1 is a methylation and expression quantitative trait locus coupled to an AD-risk associated haplotype, which displays enhancer-like characteristics and contacts the PM20D1 promoter via a haplotype-dependent, CCCTC-binding-factor-mediated chromatin loop. (nature.com)
Expression quantitative trait loci (eQTLs) for differentially expressed RNAs were obtained from a publicly available dataset. (lu.se)

Plant growth habit is an important and complex agronomic trait and is associated with yield, disease resistance, and mechanized harvesting in peanuts. (frontiersin.org)
It is suggested that the resistance to bacterial blight is quantitative, with a predominance of additive genetic effects. (usp.br)
Improving yield traits, resistance to biotic and abiotic stresses, and fiber quality properties is one of the urgent tasks of cotton research and production around the world. (usda.gov)

This chapter discusses the taxonomic and evolutionary studies of cotton, its economic importance in the world, QTL mapping analysis of world researchers, as well as practical examples of MAS technology for exploiting the cotton genetic diversity. (usda.gov)

Genetic analysis of multiple measures in longitudinal studies provides a valuable opportunity to understand genetic architecture and biological variations of complex diseases. (intlpress.com)

Insight in genome-wide association of metabolite quantitative traits by exome sequence analyses. (ox.ac.uk)
Metabolite quantitative traits carry great promise for epidemiological studies, and their genetic background has been addressed using Genome-Wide Association Studies (GWAS). (ox.ac.uk)
To estimate the causal effects of RNAs on traits, a two-sample Mendelian randomisation analysis was performed using public genome-wide association study (GWAS) data. (lu.se)

http://rsb.info.nih.gov/nih-image) of video images of whole flowers taken in a plane perpendicular to the long axis of the corolla tube, which… As a result, there is a large discrepancy between the known heritability of most traits and the fraction of that heritability that can be explained by known causative genetic variants (Manolio et al. (web.app)
Are quantitative trait-dependent sampling designs cost-effective for analysis of rare and common variants? (biomedcentral.com)
In replicate 1 data, we applied the designs in association analysis of Q1 with both rare and common variants in the FLT1 gene, based on knowledge of the generating model. (biomedcentral.com)
In contrast, taking a simple random sample from the cohort will tend to select individuals from the central part of the trait distribution and can fail to sample individuals with low-frequency variants. (biomedcentral.com)
Combined GWAS and exome analyses of metabolites detected by high-resolution 1H-NMR is a robust approach to uncover metabolite quantitative trait loci (mQTL), and the likely causative variants in these loci. (ox.ac.uk)
The common genetic variants associated with complex traits typically lie in noncoding DNA and may alter gene regulation in a cell type-specific manner. (nih.gov)

Still, it would be almost thirty years until the theoretical framework for evolution of complex traits would be widely formalized. (wikipedia.org)
In this article, we use standard cross designs, such as backcross or F2, to propose some hazard regression models, namely, the additive hazards model in quantitative trait loci mapping for age-at-onset, although the developed method can be extended to more complex designs. (bepress.com)

A quantitative trait locus (QTL) is a locus (section of DNA) that correlates with variation of a quantitative trait in the phenotype of a population of organisms. (wikipedia.org)
For early geneticists, it was not immediately clear that the smooth variation in traits like body size (i.e., incomplete dominance) was caused by the inheritance of single genetic factors. (wikipedia.org)
Although Darwin himself observed that inbred features of fancy pigeons were inherited in accordance with Mendel's laws (although Darwin didn't actually know about Mendel's ideas when he made the observation), it was not obvious that these features selected by fancy pigeon breeders can similarly explain quantitative variation in nature. (wikipedia.org)
Castle's conclusion was based on the observation that novel traits that could be studied in the lab and that show Mendelian inheritance patterns reflect a large deviation from the wild type, and Castle believed that acquisition of such features is the basis of "discontinuous variation" that characterizes speciation. (wikipedia.org)
In an early summary of the theory of evolution of continuous variation, Sewall Wright, a graduate student who trained under Castle, summarized contemporary thinking about the genetic basis of quantitative natural variation: "As genetic studies continued, ever smaller differences were found to mendelize, and any character, sufficiently investigated, turned out to be affected by many factors. (wikipedia.org)
We performed EWAS meta-analysis across results from the two data sets, with adjustment for sex and surrogate variables that reflect major sources of biological variation and technical confounding such as cell type, batch, and ancestry. (springer.com)
Depending on the traits and the site, the QTL accounted for 12-81% of the genetic variation. (sabanciuniv.edu)
In the process called quantitative trait loci (QTL) mapping, attempts are made to find significant correlations between marker alleles and the phenotypic variation, or disease state. (bmj.com)

What's required is linkage disequilibrium between a QTL and a marker (since, if the traits were in Hardy-Weinberg, there would be no association between a marker genotype and a QTL genotype), which is maximized in inbred strains but can… traits behave according to the model of monogenic or simple gene inheritance in which one gene corresponds to one trait. (web.app)

A method is presented to estimate the biometric parameters of a quantitative trait locus linked to a genetic marker when both loci are segregating in the F-2 generation of a cross between two inbred lines. (agri.gov.il)

celaoforever/SHEsisPlus: a software package for analysis of genetic association, Hardy-weinberg equilibrium, linkage disequilibrium and haplotype construction at multiallelic polymorphism loci, compatible for both diploid and polyploid species. (github.com)
A total of 149 plants were selected from the hybrid population as the mapping population, and after sequence-related amplified polymorphism and simple-sequence repeat marker analysis were conducted we constructed molecular genetic maps of the parents. (geneticsmr.com)

Provide a sustainable biological resource to investigate the genetical control of quantitative traits in Conifers. (le.ac.uk)
New DNA analysis techniques in the past decade have fueled an exponential increase in the amount of available biological information. (concord.org)

Due to their polygenic architectures, such traits are difficult to investigate with genetic mapping. (scilifelab.se)
The map position of cDNA clones relative to the predicted location of quantitative trait loci will provide new opportunities to unravel the genetic control of polygenic traits in forest tree species. (le.ac.uk)

Because ascertainment by the phenotype needs to be taken into account, simple selection from the tails of the trait distribution complicates inference. (biomedcentral.com)

Major traits identified for herbage production were leaf elongation rate (LER), leaf lamina length (LL), tiller number (TN) and tiller weight (TW), and for increased seed production were seed yield per head (SdYH), reproductive tiller number (RT), reproductive tillers with matured heads (TMH), florets per head (FH), spikelets per head (SH), florets per spikelet (FS), floret site utilization (FSU) and seed weight (TSW). (massey.ac.nz)

Construction of High-Density Genetic Map and Mapping Quantitative Trait Loci for Growth Habit-Related Traits of Peanut (Arachis hypogaea L. (frontiersin.org)
Plant area index ( PAI ) estimated from below‐canopy hemispherical images, as well as a suite of thirteen traits assessed by manual destructive harvests, were measured in a Setaria recombinant inbred line mapping population segregating for aboveground productivity and architecture. (osti.gov)
ex Tanaka] × 'Miyagawa Wase') and 'Yoshida' ponkan (Citrus reticulata Blanco 'Yoshida'), a SNP-based genetic linkage map was constructed and quantitative trait locus (QTL) mapping of four fruit-quality traits (fruit weight, sugar content, peel puffing, and water rot) was performed. (citrusgenomedb.org)
We used the interval mapping method to conduct a quantitative trait locus (QTL) analysis of grape weight and soluble solid content of the mapping population. (geneticsmr.com)
QTL were identified using an improved method of analysis, whole genome average interval mapping. (sabanciuniv.edu)
Quantitative trait locus (QTL) mapping locates and estimates the effect of genetic loci that regulate quantitative traits. (jax.org)
Breeding opportunities for crop improvement have been greatly enhanced by quantitative trait loci (QTL) mapping technology. (usda.gov)
Semiparametric Quantitative-Trait-Locus Mapping: II. (bepress.com)

The overarching aim of the Epigenetics common cause of gastric cancer, Pan-cancer genoMe and Group (EGE) is to advance the which is the third most common cause tranScriPtoMe analySiS and understanding of the role of epigenetic of cancer-related deaths worldwide. (who.int)

Analysis of image‐based estimates of PAI successfully identified all four QTL hot spots for biomass production. (osti.gov)
On the use of the moments method of estimation to obtain approximate maximum likelihood estimates of linkage between a genetic marker and a quantitative locus. (agri.gov.il)
The resulting trait distribution is bimodal, violating the usual linear regression assumptions and can produce distorted effect estimates and type I errors greater or less than nominal. (biomedcentral.com)
For species of management concern, accurate estimates of inbreeding and trait depression are crucial for the species' future. (biorxiv.org)

Life history traits such as fecundity are important to evolution because they make up components of lifetime fitness. (scilifelab.se)

We are proud to work together with the leading biotech company in Sweden for biomarker panel analyses in epidemiology, OLINK Proteomics AB, Uppsala, and its representatives! (lu.se)

Analyses of the mitochondrial hydroxysteroid dehydrogenase (HSD17B10) uncover the RNA-binding specificity of an enigmRBP. (nature.com)

Use of trait-dependent sampling designs in whole-genome association studies of sequence data can reduce total sequencing costs with modest losses of statistical efficiency. (biomedcentral.com)
In a quantitative trait (QT) analysis of data from the Genetic Analysis Workshop 17 mini-exome for unrelated individuals in the Asian subpopulation, we investigate alternative designs that sequence only 50% of the entire cohort. (biomedcentral.com)
In this paper, stochastic functional linear models are developed for temporal association analysis at gene levels to analyze sequence data and longitudinally measured quantitative traits. (intlpress.com)
Functional data analysis techniques are utilized to reduce high dimensionality of sequence data and draw useful information. (intlpress.com)

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The quantitative trait locus (QTL) analysis of the growth habit-related traits was conducted based on phenotyping data from seven environments. (frontiersin.org)
12 Jun 2009 Article · Figures & Data · Info & Metrics · PDF It focuses on how recent metabolic quantitative trait loci (QTL) studies enhance For instance, the analysis of genetic mutants in the Escherichia coli lactose Download PDF. (web.app)
It can not only analyze case/control data, but also quantitative trait data. (github.com)
The purpose of our analyses of the Genetic Analysis Workshop 17 (GAW17) mini-exome data is to compare alternative sampling strategies with respect to relative efficiency. (biomedcentral.com)
We consider the analysis of sequencing data for the entire cohort as the ideal against which to compare sampling designs in which only 50% of the cohort is sequenced. (biomedcentral.com)
With a few exceptions, most methods integrate more than two different data sources by combining evidences obtained from pairwise analyses (Van Steen & Malats, 2014). (researchgate.net)
The vast amount of heterogeneous omics data, encompassing a broad range of biomolecular information, requires novel methods of analysis, including those that integrate the available levels of information. (researchgate.net)
Combined analyses of these and recently published data sets define the core RBP repertoire conserved from yeast to man. (nature.com)
The proposed methodologies will be evaluated by simulation studies and demonstrated in an actual data analysis of forest tree growth. (bepress.com)
It should also include a disclaimer which credits any analyses, interpretations, or conclusions reached to the author (recipient of the tape) and not to NCHS, which is responsible only for the initial data. (cdc.gov)

Public datasets and online software at WebQTL [ 10 , 13 ] allow free exploration of the characteristics of this form of analysis [ 14 ]. (biomedcentral.com)
Evidence for sex bias and potential sibling correlation suggests that autism traits in the RASopathies share characteristics with autism traits in the general population and clinical ASD population and can shed light on idiopathic ASDs. (bmj.com)

Bayesian robust analysis for genetic architecture of quantitative traits. (vldb.org)

This explosion has turned databases such as the Jackson Laboratory's Mouse Genome Database into critical research tools and has paved the way for statistical methods such as Quantitative Trait Loci (QTL) analysis. (concord.org)

Twenty‐seven quantitative trait loci ( QTL ) were detected for manually collected traits associated with biomass production. (osti.gov)

Using two-sample Mendelian randomisation, we found 52 mRNAs to have a causal effect on anthropometric traits (n=23) and lipid metabolism traits (n=10). (lu.se)

GENIQUEST stands for Genomics Inquiry through Quantitative Trait Loci Exploration with SAIL Technology. (concord.org)

abstract = "A number of familial diseases have an age-of-onset component, which can be considered as a censored quantitative trait. (elsevierpure.com)

Marker-trait associations were assessed by using QTDT (a general test of association for quantitative traits) and the family-based association test (FBAT), and haplotype analysis was performed by using FBAT and the GeneHunter Transmission/Disequilibrium Test TDT. (nih.gov)
Power of daughter and granddaughter designs for determining linkage between marker loci and quantitative trait loci in dairy cattle. (agri.gov.il)

mRNAs in the MOD cluster showed a possible causal effect on anthropometric traits, lipid metabolism traits and blood cell fractions. (lu.se)

Anatomy4

Organisms5

Diseases1

Chemicals and Drugs1

Analytical, Diagnostic and Therapeutic Techniques and Equipment13

Psychiatry and Psychology1

Phenomena and Processes32

Disciplines and Occupations1

Anthropology, Education, Sociology and Social Phenomena1

Technology, Industry, Agriculture3

Information Science1

Health Care5

Loci analysis2

Genetics7

QTLs8

Locus analysis2

Gene expression5

Phenotypes6

Genomic4

Genes22

Putative1

Agronomic traits1

Populations5

Linkage analyses2

Genotypes3

EQTL1

Markers6

Variance3

Qualitative3

Phenotypic standard3

Detection2

Expression2

Resistance3

Evolutionary1

Longitudinal1

Genome-wide3

Variants6

Complex2

Variation8

Maximized in inbred1

Biometric1

Polymorphism2

Biological2

Polygenic2

Phenotype1

Yield1

Mapping8

Transcriptome1

Estimates4

Fecundity1

Epidemiology1

Mitochondrial1

Sequence4

Functional1

Data10

Characteristics2

Robust1

Statistical1

Biomass1

Mendelian1

Exploration1

Abstract1

Marker2

Cluster1