Quantitative marker results reproducibility of results. Medical search. Frequent questions

Whether it's evaluating analyte specificity and sensitivity, new reagent lot qualification, method-to-method comparison, or to assess consistency in test run repeatability and reproducibility studies, our comprehensive set of panel products serve nearly all applications of IVD validation protocols to enable confidence in your test results. (seracare.com)
In addition the repeatability and reproducibility of the MA test was assessed by comparing results of five replicate tests of 26 urine samples, interpreted by two different readers. (vin.com)

AFLP not only has higher reproducibility, resolution, and sensitivity at the whole genome level compared to other techniques, but it also has the capability to amplify between 50 and 100 fragments at one time. (wikipedia.org)
CONCLUSION/SIGNIFICANCE: The concordance in quantitative estimates of total neuron number derived from NeuN- and Giemsa-stained sections provides evidence for the sensitivity and specificity of NeuN as a neuronal marker in the G-mini. (bvsalud.org)
Although time-consuming, quantitative validation of IHC should always be considered in stereological studies if there is doubt of the sensitivity, specificity, or reproducibility of cell type markers. (bvsalud.org)
AccuSpan linearity panels are designed to span the dynamic range of quantitative infectious disease assays and evaluate the analytical sensitivity of instrumentation. (seracare.com)
Although the sensitivity of these tests may be high, their use as quantitative tools for assessment of anergy is limited. (cdc.gov)
Since the development and validation of multiplex assays are very complex and time consuming, we've used our vast expertise to develop novel approaches to address multiplex cross-talk, optimize reagents to improve sensitivity, apply a clinical-like approach to improve reproducibility, and develop antibodies and antigens for greater specificity. (bioradiations.com)

Given the reproducibility, specificity, scalability, and ability to test any tissue sample following DNA extraction, qPCR presents a viable platform for biomarker and diagnostic development. (infectiousdiseaseadvisor.com)

The authors ask whether disparate results of recent consensus conferences, which ``good old'' clinical markers, if optimally analysed, might have attempted, using simple criteria, to define ``low- have a similar discriminating power with regard to breast risk'' patients for whom adjuvant chemotherapy should cancer prognosis as the microarray gene expression pro- not be recommended. (lu.se)
In the past, transla- progesterone receptor (PgR) expression, and all of the tional research focused on single biological markers following features: pT 6 2 cm, grade I, age P 35 years which could putatively discriminate patients' prognosis should be considered in this low-risk category, whereas or treatment response. (lu.se)
By the from these conventional markers to determine individual same token, within the moderate/high-risk groups, pa- prognosis [6]. (lu.se)
For example, identifying transcriptional changes that occur between normal and disease states may lead to markers of progression or prognosis, knowledge of molecules that can be pharmaceutically corrected, or to an understanding of the cascade of molecular events that have occurred. (biomedcentral.com)

Systematic review using standard (quantitative) and realist (mainly qualitative) methodology. (nih.gov)
Although both qualitative and quantitative studies are reviewed, the quantitative studies are emphasised because of their inherent advantages and because they directly reflect the digital data on which this imaging modality is based. (ersjournals.com)
Quantitative and qualitative analyses of extracts were carried out by GC-MS and RP-HPLC methods. (eco-vector.com)
The quantitative and qualitative data weredone simultaneously. (bvsalud.org)
Qualitative data were subjected to thematic analysis, while the quantitative data were analyzed with descriptive statistics and chi-square test.Results:The mean age of mothers is ± SD 28.6 ± 5.4. (bvsalud.org)

The assessment of TILs by digital image analysis might be useful for standardization in the future, since this approach has the potential, for example, to determine the number of TILs per mm² stromal tissue as an exact measurement contrary to the approximate semi-quantitative evaluation suggested at this moment. (tilsinbreastcancer.org)
A commercial semi-quantitative ELISA-based test for the measurement of feline MA is available, but normal urine albumin concentrations have not been well established for feline patients. (vin.com)
Validation of a semi-quantitative FFQ using food records. (cambridge.org)
To validate an eighty-nine-item semi-quantitative FFQ for measurement of nutrient intakes in elderly women. (cambridge.org)
Our aim was to develop a semi-quantitative FFQ for elderly women and to evaluate the relative validity of nutrient intakes estimated by the FFQ as compared with 3 d food records. (cambridge.org)

Alternatively, cells were fixed in 4% formaldehyde, permeabilized with 0.01% of saponin solution in PBS and stained using fluorophore-conjugated antibodies against β-tubulin III (TUJ-1) neuronal marker (1:100 dilution). (moleculardevices.com)
Validate your antibodies to improve reproducibility? (reproduciblescience.org)
Indeed, problems with antibodies are thought to have led many drug developers astray and generated a host of misleading or irreproducible scientific results. (reproduciblescience.org)

The AFLP technology has been used in criminal and paternity tests, also to determine slight differences within populations, and in linkage studies to generate maps for quantitative trait locus (QTL) analysis. (wikipedia.org)
Suppression subtractive hybridization (SSH) and quantitative trait locus (QTL) mapping were the strategies used to find leaf scald resistance-associated genes and molecular markers in sugarcane. (lsu.edu)

Six institutions collaborated to: (1) optimize an automated six-plex assay focused on the PD-1/PD-L1 axis, (2) assess intersite and intrasite reproducibility of staining using a locked down image analysis algorithm to measure tumor cell and immune cell (IC) subset densities, %PD-L1 expression on tumor cells (TCs) and ICs, and PD-1/PD-L1 proximity assessments. (akoyabio.com)
Comparison of the percent positive cells for each marker between mIF and IHC revealed that enhanced amplification in the mIF assay was required to detect low-level expression of PD-1, PD-L1, FoxP3 and CD68. (akoyabio.com)
Following optimization, an average equivalence of 90% was achieved between mIF and IHC across all six assay markers. (akoyabio.com)
The end goal of the SMARTS approach is to deliver end users with actionable results using the five performance characteristics of SMARTS to guide assay design and acceptance criteria. (bioradiations.com)
An unselected design is optimal where preliminary evidence regarding treatment benefit and assay reproducibility is uncertain (eg, epidermal growth factor receptor and lung cancer). (elsevierpure.com)
Hybrid designs are appropriate when preliminary evidence demonstrate the efficacy of certain treatments for a marker-defined subgroup, making it unethical to randomly assign patients with that marker status to other treatments (eg, multigene assay and breast cancer). (elsevierpure.com)

The development of molecular markers associated with incompatible/compatible reaction can overcome this limitation. (lsu.edu)
Implementation of molecular markers to identify suitable genotypes speeds up the breeding progress by enhancing selection efficiency. (geneticsmr.com)
The failure of these trials is partly due to the lack of effective molecular markers or the minimal validation of known molecular markers in diverse multi-ethnic populations. (biomedcentral.com)
Advances in molecular biotechnology have introduced new generations of molecular markers for use in the genetic improvement of farm animals. (biomedcentral.com)
This review gives a brief summary on the development of genetic markers including both the classical genetic markers and more advanced DNA-based molecular markers. (biomedcentral.com)
By the 1980s, many different types of DNA molecular markers had been explored, e.g. (biomedcentral.com)

Taken together, these results suggest that spectral resting-state EEG holds promise for sensitive measurement of functioning and change in persons with chronic aphasia. (frontiersin.org)
This small prospective study from a single center showed that the renal cortex's color Doppler sonographic dynamic tissue perfusion measurement had very good intraobserver reproducibility. (medscimonit.com)

Results We identified a homozygous 2 bp deletion in MMP21, encoding matrix metalloproteinase-21, as the sole coding mutation that segregated with the phenotype. (bmj.com)

In the first International Guidelines on TIL-assessment in breast cancer we proposed to develop an inter-laboratory Ring study to assess the reproducibility and clinical validity of TILs assessment, including machine learning algorithms. (tilsinbreastcancer.org)
However, sufficient genetic markers for evaluating the population structure and other aspects of available animal genetic resources are necessary to assess genetic diversity. (biomedcentral.com)

In addition, we developed a microanalytical method suitable for the quantitative determination of the sugar anhydride levoglucosan in low-volume samples of atmospheric fine particulate matter. (cdc.gov)
The aim is to develop and compare methods for the quantitative determination of coenzyme Q10 in order to identify the most sensitive, simple and reproducible one. (eco-vector.com)
These assays are performed on a Behring Nephelometer for quantitative CRP determination. (cdc.gov)
The graphite furnace atomic absorption spectrophotometer is equipped with an automatic sampler, has accurate sample determination results and has good precision, but it has strict requirements of experimental conditions and demands for a large current and high voltage. (justia.com)

Genetic markers added nothing to models over clinical and sociodemographic factors. (nih.gov)
This is at odds with results from high-throughput technologies such as gene expression profiling and genomic assays, which focus on identifying individual patient groups with particular clinical behavior. (tilsinbreastcancer.org)
For more than 30 years, AccuSpan™ linearity panels have been a trusted source of validation material to clinical laboratories worldwide that test for quantitative molecular analytes. (seracare.com)
TsolR13 is a novel real-time quantitative polymerase chain reaction (qPCR) target and may be a useful tool for diagnosing neurocysticercosis from plasma and cerebrospinal fluid (CSF), according to study results published in Clinical Infectious Diseases . (infectiousdiseaseadvisor.com)
These results were confirmed by a clinical study scrutinising 8 blood markers in obese patients. (researchgate.net)
conrmed by a clinical study scrutinising 8 blood markers in obese patients. (researchgate.net)
Professor Stephen Bustin is a world-renowned expert on quantitative PCR, and his research focuses on translating molecular techniques into practical, robust and reliable tools for clinical and diagnostic use. (aru.ac.uk)

Nevertheless, available evidence indicates Accepted: 22 September 2021 Published: 29 October 2021 low CFVR is an equally important prognostic marker in both men and women. (readkong.com)
However, evidence in humans suggests that early increases in albuminuria (microalbuminuria, MA) reflect glomerular damage undetectable by the traditional UPC ratio, and may serve as both a negative prognostic marker and also potentially contribute to renal damage in cases of renal failure, although MA may also be found in conditions affecting glomerular function other than renal failure. (vin.com)

This study tested the claim that digital PCR (dPCR) can offer highly reproducible quantitative measurements in disparate labs. (reproduciblescience.org)
Our findings show that dPCR has demonstrable reproducibility across a large number of laboratories without calibration and could enable the reproducible application of molecular stratification to guide therapy, and potentially for molecular diagnostics. (reproduciblescience.org)
TILs have been shown to be a reliable and reproducible marker of tumor immunogenicity in breast cancer. (tilsinbreastcancer.org)

This marker is challenging to quantify reproducibly using qPCR or NGS due to the presence of competing wild type sequences and the need for calibration. (reproduciblescience.org)

Genome-wide association studies that link phenotypes to thousands of single nucleotide polymorphism markers are nowadays common practice for such analyses. (nih.gov)
Typically, in unraveling interesting biological phenomena, inferring changes in expression is a critical, yet initial step of the discovery pipeline, and the results often feed into downstream interpretive analyses. (biomedcentral.com)
Adaptive analysis designs allow for prespecified marker-defined subgroup analyses of data from an RCT. (elsevierpure.com)

However, none of these products are licensed for use as DTH skin-test antigens, and none are certified for lot-to-lot reproducibility for this purpose. (cdc.gov)

Proteinuria (in the absence of lower urinary tract disease) is therefore usually a marker of renal damage or dysfunction (glomerular or tubular), although this may result from either primary or secondary renal disease. (vin.com)

Additionally, we assessed other commonly used glial markers and discussed how to evaluate the advantages and disadvantages of these markers for stereological estimation of cell number. (bvsalud.org)
The intraclass correlation coefficient (ICC) and Bland-Altman plot were used to evaluate inter-observer reproducibility. (gencat.cat)
The criteria established in 1971 to evaluate carcinogenic risk to humans were adopted by the working groups whose deliberations resulted in the first 16 volumes of the IARC Monographs series . (who.int)

Quantitative traits in plants are controlled by a large number of genes and their interaction with the environment. (nih.gov)
The application of genomic prediction models that take into account the effects of all individual loci may greatly enhance the elucidation of the genetic architecture of quantitative traits in plants. (nih.gov)
Consequently, the application of morphological markers is limited in the evaluation of quantitative traits. (biomedcentral.com)

At AACR last week, the firm presented updated data from its intra- and inter-laboratory reproducibility experiments with the technology, conducted with ResearchDx. (genomeweb.com)

Objective Ki67 is a prognostic and predictive marker in breast cancer (BC). (gencat.cat)
Methods: Designs for predictive marker validation are broadly classified as retrospective (ie, using data from previously well-conducted randomized controlled trials [RCTs]) versus prospective (enrichment, unselected, hybrid, or adaptive analysis). (elsevierpure.com)

Finally, we tested generalizability of our approach using a second, open-source, image analysis platform and found similar results. (frontiersin.org)
She was compiling a bibliography about the reproducibility of experiments, and one of the papers, a meta-analysis, found that scientists routinely fail to explain how they choose the number of samples to use in a study. (reproduciblescience.org)
Thus, AmpliSeq stands as a very sensitive and cost-effective approach for very large scale gene expression analysis and mRNA marker screening with high accuracy. (biomedcentral.com)
At present, DNA molecular marker techniques are widely applied in the fields of germplasm identification, phylogenetics, and genetic structural analysis. (biomedcentral.com)
RNA-seq has been a boon to the quantitative analysis of transcriptomes. (biomedcentral.com)
From an analysis perspective, there are several ways to approach RNA-seq data to unravel differential transcript usage, such as annotation-based exon-level counting, differential analysis of the percentage spliced in, or quantitative analysis of assembled transcripts. (biomedcentral.com)
Results: Well-designed retrospective analysis from well-conducted prospective RCTs can bring forward effective treatments to marker-defined subgroups of patients in a timely manner (eg, KRAS and colorectal cancer). (elsevierpure.com)

To assist in the evaluation of skeletal status, two markers of bone turnover are being measured: a) bone alkaline phosphatase, a formative marker in serum, and b) NTX, a resorptive marker in urine. (cdc.gov)
All of these DNA-based markers contain specific advantages and have played significant roles in the evaluation of genetic diversity in farm animals. (biomedcentral.com)
The evaluation of farm animal genetic resources through morphological markers is based on subjective judgments and descriptions, and the conclusions reached are often not completely accurate. (biomedcentral.com)

In this case, the data transfer of these trials will be deferred until the trial results are published. (eortc.be)
They would also help standardize pathology results within and across trials. (tilsinbreastcancer.org)
This systematic review shows the diversity of end-points used in bronchiectasis and suggests approaches that may improve the success rate and reproducibility of trials. (ersjournals.com)

In small animal models, the ability to profile multiple cytokine markers using conventional single-plex ELISA techniques is often restricted by the requirement of a large sample volume. (bioradiations.com)

Quantitative data were tabulated to compare model components and statistical properties. (nih.gov)
Please provide the primary and secondary endpoints, available reference values for all endpoints, describe markers prevalence, methods of adjustment for multiple testing or comparison planned, statistical tests or regression models used with significance levels. (eortc.be)
However, the application of these criteria would biomarkers could still be useful if analysed with advanced result in systemic therapy being assigned to a large statistical methodologies, collecting information derived number of patients who do not really need it. (lu.se)

METHODOLOGY/PRINCIPAL FINDINGS: We propose a method to validate existing antibody based cell type markers for stereological application. (bvsalud.org)

However, the resulting data are not scored as length polymorphisms, but instead as presence-absence polymorphisms. (wikipedia.org)
A number of proactive steps are underway to improve the rigor and reproducibility of the data reported in the Journal of Neurophysiology. (reproduciblescience.org)
Recent data indicate that high BAALC expression levels may also be used as marker for residual disease following acute myeloid leukemia treatment. (oncotarget.com)
Detailed, quantitative evaluations of epidemiological data may be made in the Monographs , but without extrapolation beyond the range of the data available. (who.int)
Quantitative extrapolation from experimental data to the human situation is not undertaken. (who.int)

It was our hypothesis that the dose-dependent increase in urinary methoxyphenols observed following ingestion or inhalation of woodsmoke combustion products can be related in a quantitative manner to environmental woodsmoke, and thereby provide a biomarker basis for assessment of woodsmoke exposure in occupationally and environmentally exposed populations. (cdc.gov)
such information is much more precise for the assessment of genetic diversity than previous markers. (biomedcentral.com)
Although several toxicological profiles have been developed for petroleum products and for specific chemicals found in petroleum, TPH test results have been too nonspecific to be of real value in the assessment of its potential health effects. (cdc.gov)

The second step is quantitative risk estimation. (who.int)

In this talk, I will motivate the need for experimental reproducibility as a necessary aspect for healthy progress as accepted by other communities. (reproduciblescience.org)

There are many advantages to AFLP when compared to other marker technologies including randomly amplified polymorphic DNA (RAPD), restriction fragment length polymorphism (RFLP), and microsatellites. (wikipedia.org)
A linkage map was constructed using 89 F1 progeny of a cross between the cultivars LCP 85-384 (resistant) and L 99-226 (susceptible) using simple sequence repeat (SSR), leaf scald responsive genes-derived SSR and single nucleotide polymorphic (SNP) markers. (lsu.edu)

In genetic diversity studies, the most frequently used markers are microsatellites. (intechopen.com)

however, the erratic symptom expression hinders the reliability and reproducibility of the selection process. (lsu.edu)
A third priority addressed concerns about the reliability of biomedical research results. (aru.ac.uk)

Chromosomes are the carriers of genetic material and chromosome mutations are crucial sources of genetic variation [ 5 ], we can use these mutations as markers to determine the specific location of a gene on the chromosome, and its position relative to other genes. (biomedcentral.com)

As a result, AFLP has become extremely beneficial in the study of taxa including bacteria, fungi, and plants, where much is still unknown about the genomic makeup of various organisms. (wikipedia.org)
Several results in this area have identified genomic/transcriptomic or proteomic features which in hindsight are associated with particular histological features. (tilsinbreastcancer.org)

Many diseases and infections, including cancer and certain viral infections (especially HIV infection), and some immunosuppressive drugs may result in a transient or continuing suppression of cellular hypersensitivity mediated by T-lymphocytes. (cdc.gov)
Transient suppression or CRISPR/Cas9-mediated deletion of mmp21 in zebrafish embryos induced cardiac looping defects, with concomitant disruption of laterality markers in the lateral plate mesoderm and disrupted notch signalling in vitro and in vivo. (bmj.com)

The present study resulted in a strong platform for future functional validation of the genes to ascertain their role in leaf scald resistance and marker validation in larger and diverse populations toward development of allele-specific markers for their use in breeding resistant sugarcane varieties. (lsu.edu)
As such, this study was undertaken to quantify TRWP in PM2.5 at roadside locations in urban centers including London, Tokyo and Los Angeles, where vehicle traffic is an important contributor to ambient air PM. The samples were analyzed using validated chemical markers for tire tread polymer based on a pyrolysis technique. (mdpi.com)
This study was carried out to probe genetic diversity among 21 maize genotypes using 20 inter simple sequence repeat (ISSR) markers. (geneticsmr.com)

In earlier studies, morphological markers and eco-geographical factors were used to represent diversity, and after that, chromosomal karyotyping was developed. (biomedcentral.com)
Studies have found that unadjusted flow and volume values are more predictive of patient outcomes than ethnically adjusted values, suggesting that these adjustments may result in under-recognition (and thus undertreatment) of true decreases in pulmonary function in non-White individuals. (msdmanuals.com)

An algorithm capable of reliably and accurately tracking changes in tumor volume would be of value as an adjunct marker in following up patients with cerebral tumors. (ajnr.org)
This method also relies on the hypothesis that the largest area is an accurate adjunct marker for tumor volume. (ajnr.org)

Using dPCR, eighteen laboratories were able to quantify the G12D marker within 12% of each other in all samples. (reproduciblescience.org)
Still others have identified simple proteomic surface markers to quantify particular cells or vesicles of interest as an indicator of disease. (genomeweb.com)

Investigators reported that in 4,000 patient cases - more than 70 percent of which were from physician practices that self-identified as community-based - they were able to generate results for 98 percent of samples submitted. (genomeweb.com)

Conse- markers could improve prognostic assessments and help quently, one might speculate that resources could be more to better discriminate which subjects are likely to re- profitably spent for the promotion of quality assurance spond to the various tailored systemic treatments. (lu.se)
The following is a brief summary on the principles and advancements of primary genetic markers involved in assessments of Animal Genetic Resources (AnGR). (biomedcentral.com)

Perhaps the weak link in the approach of the tient outcome is also highly variable and depends on Lund group is their faith in the reproducibility of biological differences among the tumours. (lu.se)

This systematic review demonstrates a need for guidance to standardise definitions and design features to improve reproducibility and increase the likelihood of demonstrating statistically significant benefits with new therapies. (ersjournals.com)

Combining spatial and abundance information yielded an unprecedented quantitative view of HeLa cell anatomy and organellar composition, at the protein level. (elifesciences.org)

The primary objective of this proposal was to develop biological markers of human exposure to woodsmoke. (cdc.gov)

This review will help us better understand the characteristics of different genetic markers and the genetic diversity of animal genetic resources. (biomedcentral.com)

Although the canonical counting provided the best results overall, several non-canonical approaches were as good or better in specific aspects and most counting approaches outperformed the evaluated event- and assembly-based methods. (biomedcentral.com)
Several approaches are discussed in this document for interpreting TPH and related analytical results. (cdc.gov)

Inaccurate staining may cause both over- and underestimation of the total cell number and inflict considerable limitation when analyzing the results. (bvsalud.org)
The forced expiratory flow averaged over the time during which 25 to 75% of the FVC is exhaled may be a more sensitive marker of mild, small airway airflow limitation than the FEV1, but the reproducibility of this variable is poor. (msdmanuals.com)

Even though these array-based methods are high-throughput, they are physically limited by probe density and suffer from noisy signals resulting from background noise due to cross hybridization and signal saturation [ 3 , 8 - 10 ]. (biomedcentral.com)

The resulting technique maps the location of most of the proteins in a human cancer cell line and, in addition, determines how many copies of each protein there are. (elifesciences.org)
With the rapid development of modern biotechnology, biochemical markers, such as proteins and isozymes, were utilized. (biomedcentral.com)
[ 12 ] Iron toxicity occurs as a result of the ferrous reactive forms of iron that reacts with oxidants, forming a complex that rapidly degrades proteins and DNA of a cell. (medscape.com)

A novel real-time quantitative polymerase chain reaction target has been identified and may be a useful tool for diagnosing neurocysticercosis. (infectiousdiseaseadvisor.com)
Early detection of measurable residual disease (MRD) through multiparameter flow cytometric (MFC) or quantitative real time PCR (qRT-PCR) assays may allow treatment intervention before overt relapse occurs [ 3 - 5 ]. (oncotarget.com)

Twenty-one laboratories measured four blinded samples containing different quantities of a KRAS fragment encoding G12D, an important genetic marker for guiding therapy of certain cancers. (reproduciblescience.org)

METHODS: We used the Knowledge to Action framework, which was developed to map how science is translated into effective health programs, to examine how the evidence-based intervention from the 2002 Diabetes Prevention Program trial was translated into the Centers for Disease Control and Prevention's large-scale National Diabetes Prevention Program, eventually resulting in payment for the lifestyle intervention as a Medicare-covered service. (cdc.gov)

For purposes of this profile, the term TPH refers not only to analytical results, but also to environmental and health properties of PHCs. (cdc.gov)

Investigators have evaluated groups of persons with HIV infection for their ability to mount a DTH response and have related the results to other measures of HIV infection -- most commonly, CD4 T-lymphocyte counts. (cdc.gov)

The recommended practices address the benefits of using a quality management system approach, factors to consider before introducing new tests, establishment and verification of test performance specifications, the total laboratory testing process (which consists of the preanalytic, analytic, and postanalytic phases), confidentiality of patient information and test results, and personnel qualifications and responsibilities for laboratory testing for inherited metabolic diseases. (cdc.gov)
Discrepancies existed in the replicate test results in 23% and 27% of the samples examined by reader 1 and 2 respectively, and on several occasions this discrepancy was between whether the sample was 'positive' or 'negative' for MA. (vin.com)
Positive TPH test results may require action on the part of land owners, local or state governments, and engineering firms called on to remove or reduce the TPH problem. (cdc.gov)

Anatomy2

Chemicals and Drugs4

Analytical, Diagnostic and Therapeutic Techniques and Equipment36

Phenomena and Processes12

Disciplines and Occupations1

Technology, Industry, Agriculture2

Information Science11

Health Care11

Repeatability and reproducibility2

Sensitivity6

Specificity1

Prognosis4

Qualitative5

Semi-quantitative5

Antibodies3

Trait locus2

Assay6

Molecular markers6

Measurement2

Phenotype1

Assess2

Determination4

Clinical7

Prognostic marker2

Reproducible3

QPCR1

Analyses3

Antigens1

Renal1

Evaluate3

Traits3

Inter-laboratory1

Predictive marker2

Analysis7

Evaluation3

Trials3

Conventional1

Statistical3

Validate1

Data5

Assessment3

Estimation1

Experimental1

Polymorphic2

Microsatellites1

Reliability2

Gene1

Genomic2

Suppression2

Study3

Studies2

Tumor2

Quantify2

Generate1

Assessments2

Differences1

Improve1

Anatomy1

Biological markers1

Genetic diversity1

Approaches2

Limitation2

Hybridization1

Proteins3

Real-time2

Laboratories1

Methods1

Analytical1

Commonly1

Test3