Quantitative marker results. Medical search. Frequent questions

Linkage studies have identified several quantitative trait loci (QTLs) for RD. The QTL on chromosome 6p21.3 has been independently replicated by several groups and spans a 16.4-Mb (13.8 cM) interval from D6S109 to D6S291. (nih.gov)
Twenty‐seven quantitative trait loci ( QTL ) were detected for manually collected traits associated with biomass production. (osti.gov)
These results show that the average size of the quantitative trait loci effect was 1.6 phenotypic standard deviations for different traits and families. (cambridge.org)
The aims of quantitative trait loci detection is the potential use of these molecular markers to increase accuracy in predicting the genetic merit of breeding and its implementation in animal breeding schemes through marker-assisted selection. (cambridge.org)
Molecular markers have been associated with Al tolerance genes or quantitative trait loci in several crops, which should facilitate development of additional tolerant varieties. (usda.gov)
Quantitative trait loci analyses (log of the odds=15) indicated association of the genetic factor within a few centiMorgan of the best evidence for Ahl [Johnson et al. (cdc.gov)
The recordings were used to generate daughter yield deviations that were first applied in a genome-wide association (GWAS) study with 17,343 markers to identify quantitative trait loci (QTL) affecting fatty acid composition, and next on high-density and sequence-level datasets to fine-map the most significant QTL on BTA13 (BTA for Bos taurus chromosome). (nofima.no)

Quantification of the S. aureus strains was performed using quantitative Polymerase Chain Reaction (qPCR) assay. (scialert.net)
The expressions of ABC transporters were measured using quantitative polymerase chain reaction . (bvsalud.org)

11 client-owned dogs with fecal quantitative PCR (qPCR) assay detected A caninum with benzimidazole (BZ) resistance genotypic markers. (avma.org)
After 24 hours, H3 acetylation was evaluated by immunofluorescence and apoptotic markers were analysed by qPCR. (ecco-ibd.eu)

The SmartMap imaging software records a full EDXRF spectrum at each and every pixel of the element image, enabling post-acquisition element image generation and comparison, and spectrum generation from user defined regions in the image with subsequent qualitative and quantitative characterisation. (horiba.com)
This requires abandoning or minimizing the use of unreliable qualitative methods and the use of quantitative methods that incorporate risks, cost, and schedule data that provide a more valid basis for decision making. (intaver.com)
These following reference ranges are based on qualitative measurement of serologic markers in an asymptomatic, nonimmunized population. (medscape.com)

Microscopic visualization of tissue by immunohistochemistry does not give quantitative results and is not considered here. (wikipedia.org)
Levels of fluorescence expression of the different markers were quantified through quantitative fluorescence immunohistochemistry (Q-FIHC). (bmj.com)

11 of these 184 samples had A caninum with genetic BZ F167Y resistance marker detection. (avma.org)
Promoter hypermethylation is an alternative pathway for gene silencing in neoplastic cells and a promising cancer detection marker. (nih.gov)
Based on clinical and laboratory data on serologic markers associated with HCC and on radiologic tests for HCC, the workshop participants concluded that serum alpha-fetoprotein (AFP) and ultrasound are the most sensitive markers available at this time for the early detection of HCC. (cdc.gov)

Marker-trait associations were assessed by using QTDT (a general test of association for quantitative traits) and the family-based association test (FBAT), and haplotype analysis was performed by using FBAT and the GeneHunter Transmission/Disequilibrium Test TDT. (nih.gov)
This study reports the results obtained in the search of chromosomal regions affecting fleece traits in a population of Angora goats in the Argentinean Patagonia. (cambridge.org)
As a result, genetic marker can be used by poultry breeders to more accurately select chickens with superior production traits. (usda.gov)
Associations between microsatellite markers and traits related to growth and fatness were sought in a resource broiler population established by Arbor Acres Farm. (usda.gov)
Following full-sib mating among the parents, 234 "BC1-F2" progeny were obtained and phenotyped for six quantitative traits. (usda.gov)
In the past years, I have been involved in several studies that contrast levels of population differentiation in putatively neutral marker genes with the corresponding data for potentially adaptive phenotypic traits to examine whether past selection pressures have been diversifying, unifying, or too weak to have any influence on the phenotypic variation. (lu.se)

Marker associations were detected in five of the ten genes, results that were corroborated by our haplotype TDT analysis. (nih.gov)
The results of the association study have thereby allowed us to significantly reduce the number of possible candidate genes and to prioritize genes for further mutation screening. (nih.gov)
Ectopic overexpression of some of these genes has resulted in enhanced Al tolerance. (usda.gov)
Additionally, expression of genes involved in organic acid synthesis has resulted in enhanced production of organic acids and an associated increase in Al tolerance. (usda.gov)
In addition, the same study was able to validate three reference or housekeeping genes in sheep to be used as controls in quantitative PCR techniques, a molecular biology technique that can quickly, easily and simultaneously quantify transcriptions of dozens of genes involved in a specific biological process. (sciencedaily.com)

For monitoring, it is important that the same assay is used, as the results from different assays are generally not comparable. (wikipedia.org)
By partnering with Quanterix and Destina, Dear and his colleagues aimed to produce an assay for miRNA-122 that has the potential to give a more rapid result. (genomeweb.com)

Quantitative PCR enables scientists, to watch every cycle of the chain reaction, via fluorescence markers. (persistencemarketresearch.com)

Identification of genetic markers of BZ resistance raises concerns about the potential animal and human impacts of resistant hookworms. (avma.org)
According to the results of the research, from a sheep's first day of infection, this protein's genetic expression increases in the tissues in which the pathogen is circulating. (sciencedaily.com)
Nevertheless, as explained by José Pérez Arévalo, one of the main researchers on this study, identifying new genetic markers will help enable future quantitative PCR studies on cytokines in sheep to be carried out successfully. (sciencedaily.com)
Results from field surveys, genetic analyses, stress-manipulation experiments and comparative studies of population structure indicate that several selection pressures, operating at both vegetative and reproductive stages, contribute to the maintenance of these pollen-color dimorphisms. (lu.se)
In the past years, I have been involved in several studies on genetic erosion - the loss of genetic variation resulting from genetic drift in small, fragmented populations. (lu.se)
Our results also indicate that the structuring of quantitative genetic variation can be relatively insensitive to landscape fragmentation, at least over the timescales considered by most conservation biologists. (lu.se)

resection of these tumors resulted in long tumor-free survival in some patients (5,6). (cdc.gov)

So that was an indicator that since bone density is a surrogate marker of fractures, there may not be an effect on fractures," she added. (medscape.com)
It has been postulated that monitoring measurable residual disease (MRD) could be used as a surrogate marker of progression-free survival (PFS) in chronic lymphocytic leukemia (CLL) patients after treatment with immunochemotherapy regimens. (haematologica.org)

Workshop participants addressed several questions regarding HCC, including whether HCC can be detected at an early stage using serologic markers or radiologic tests, whether treatment of HCC detected at an early stage can lead to prolonged survival, and whether high-risk groups for HCC in which routine screening should be considered can be identified. (cdc.gov)
Results of HBV serologic markers can be reported qualitatively or quantitatively as international units (IU) or signal per cutoff (s/c) value. (medscape.com)

It was used the instruments: socio demographic data questionnaire, biological markers: rate of CD4 and viral load and WHOQOL-HIV bref. (bvsalud.org)
HBV DNA (quantitative viral load) indicates viral burden and viral replication. (medscape.com)

In a recent study [ 32 ], the results confirm the hypothesis that the relationship between hippocampal volume and EEG rhythmicity is not proportional to the hippocampal atrophy, as revealed by the analyses of both the relative band powers and the individual alpha markers. (hindawi.com)
Contrary to the results of marker-gene analyses, our results for rare, threatened plants in Sweden and other areas provide little evidence for loss of adaptive potential in ecologically relevant characters with a polygenic basis. (lu.se)

As an important tool for the quantitative analysis of confocal microscopic data sets from co-expression of fluorescent proteins, we developed a semi-automated image analysis pipeline that allows for precise spatio-temporal quantification of protein co-localization and of the dynamics of organelle association from movies. (frontiersin.org)
Element peaks are automatically located and labelled, and quantitative analysis down to ppm levels can be carried out using the fundamental parameters method (FPM), FPM with single standard, and full standard sample calibration.Thickness calculations can also be made on nm and µm thick multi-layered structures. (horiba.com)
Results -Analysis revealed significant decreases in T 4 and fT 4 concentrations and a significant increase in TSH concentration for dogs in the peak training state, compared with concentrations for dogs in the untrained state. (avma.org)
Furthermore, Quantitative kidney histomorphometric analysis demonstrated an increase in kidney fibrosis (Col1a1) and macrophage infiltration (F4/80) in ADI mice. (asn-online.org)
A detailed quantitative analysis on the structures within the Santa Maria Basin, in terms of the amount and rate of uplift, shortening, and fault slip that has occurred in the Quaternary, was conducted using the basal contact of a regional, late Pleistocene fluvial deposit as a marker of deformation. (csulb.edu)
Quantitative analysis was performed using ImageJ software. (bmj.com)
The results of the analysis of this large population of patients with severe sepsis and septic shock demonstrate that delay in first antibiotic administration was associated with increased in-hospital mortality. (researchgate.net)
However the quantitative analysis of p53 positive cells and their localization in oral epithelium is of importance as a marker for oral squamous cell carcinoma. (bvsalud.org)
This area of research has lagged con- siderably behind the field of developing new effect markers, such as semen analysis and early pregnancy loss. (cdc.gov)

To acquire quantitative criteria of embryogenesis from time-series 3D microscopic images, image processing algorithms such as segmentation have been applied. (nature.com)

Tumor markers can be determined in serum or rarely in urine or other body fluids, often by immunoassay, ⁣⁣ but other techniques such as enzyme activity determination are sometimes used. (wikipedia.org)
The VeraSTAT-V measures levels of Serum Amyloid A (SAA), the fastest blood marker to rise in response to inflammation, quickly and accurately. (randox.com)
Results were expressed as mean and Serum high-density lipoprotein (HDL) standard deviation (SD). (who.int)

Nonetheless, systematic manipulation of effective micrometer-level MRI parameters via specialized acquisition methods, followed by fitting the resulting data to a signal representation or a biophysical model 3 , can yield parametric maps, turning scanners into quantitative diagnostic tools. (biorxiv.org)
As shown in the benchmark result, LightGBM Tuner can outperform the other methods. (medium.com)

Disease-associated mutations tend to be clustered in a small region designated the mutation cluster region (MCR) and result in a truncated protein product. (nih.gov)
Your test results will show whether you have enough PD-L1 protein in your tumor for you to benefit from a specific immunotherapy medicine. (medlineplus.gov)

Kidneys were collected for RNA sequencing or processed for histological evaluation of markers of macrophage infiltration (F4/80) and fibrosis (Col1a1). (asn-online.org)
demonstrated by co-localisation between ChemR23 or FPR2/ALX and tissue resident macrophage marker MerTK. (bmj.com)

Although some of them have had promising results in the laboratory, none have attained enough protection to be developed commercially. (sciencedaily.com)
Anatomic results and modification of the WEB shape on the follow-up examinations were independently evaluated by a core laboratory. (ajnr.org)
The laboratory or manufacturer's insert should be referenced for quantitative measurement, if required. (medscape.com)

Although mammography, ultrasonography, computed tomography, magnetic resonance imaging scans, and tumor marker assays help in the staging and treatment of the cancer, they are usually not definitive diagnostic tests. (wikipedia.org)
In this study, we investigated the feasibility of quantitative noninvasive imaging of the serotonergic metabolism in the pancreas using the PET tracer 11 C-5-hydroxy- l -tryptophan ( 11 C-5-HTP). (snmjournals.org)
The PET tracer 11 C-5-HTP can be used for quantitative imaging of the serotonergic system in the endocrine pancreas. (snmjournals.org)
Because the exocrine pancreas is devoid of these systems, we proposed that quantitative noninvasive imaging of the endocrine pancreas is feasible. (snmjournals.org)

MRI is not a quantitative measurement device by design. (biorxiv.org)

The VeraSTAT-V device measures quantitative levels of SAA in blood distinguishing systematic infection from injury prone inflammation. (randox.com)

Upregulation of activation and costimulatory markers are key events in the allergic sensitization process and have been reported to serve as indicators of skin sensitization. (cdc.gov)
Upregulation of these markers was not observed after exposure to skin irritants or prohaptens in the absence of exogenously added S9. (cdc.gov)
Consistent with tGFR decline and kidney histology, the renal transcriptome signature in ADI mice indicated upregulation of gene expression markers of fibrosis (e.g. (asn-online.org)

Conclusions and Clinical Relevance -Results of this study indicated animals with clinical signs of PPDH were more likely to undergo surgery than were animals without such signs. (avma.org)
CONCLUSIONS: Our results showed for the first time a direct role of B cells on the production of collagen by dermal fibroblasts, which is further enhanced by BAFF. (ox.ac.uk)
Although workshop participants considered a range of available data, their conclusions were not based on formal quantitative measures of cost and effectiveness of screening. (cdc.gov)

The present study evaluated the effect of hapten and prohapten exposure on cell surface markers expression (CD86, CD54 and CD40) in the human monocytic leukemia, THP-1, cell line. (cdc.gov)
This study contributes to the development of fundamental approaches for assessing embryogenesis on the basis of extracted quantitative criteria. (nature.com)
Taking vitamin D supplements did not significantly reduce the risk of fractures among adults in midlife and older adults, compared with placebo, according to results from an ancillary study of the Vitamin D and Omega-3 Trial (VITAL). (medscape.com)
Gama cautions that the results of their study on macaques with SIV may not apply to humans with HIV. (neurosciencenews.com)
Many results drawn from previous studies of the effect of antibiotic use on emergence, selection and spread of AMR have lacked a holistic view combining all aspects into one study. (europa.eu)
The participants concluded that other issues requiring further study include 1) the frequency of screening, 2) the effectiveness of using AFP as a primary screening marker for HCC, with ultrasound as an adjunct in patients with elevated AFP values, 3) the use of ultrasound as a primary screening marker for HCC, and 4) the development of more specific screening markers for HCC. (cdc.gov)
This study is quantitative, has cross sectional analytical descriptive character. (bvsalud.org)

On the basis of their chemical nature, tumor markers can be proteins, conjugated proteins, peptides and carbohydrates. (wikipedia.org)
First, we co-expressed fluorescently tagged VAPYRIN with a range of subcellular marker proteins, and secondly, we employed biochemical tools to identify interacting partner proteins of VAPYRIN. (frontiersin.org)

0.01), an anti-apoptotic marker. (ecco-ibd.eu)

They will do so because they will turn into the markers that science needs to analyze cytokine activity. (sciencedaily.com)
TBARS value according to the method of (pro-inflammatory cytokine) as markers of Mitsura and Midori. (who.int)

HIE was assessed through visual evaluation and quantitative grey-white-matter ratio (GWR) was retrospectively. (lu.se)
HIE was assessed through visual evaluation and quantitative grey-white-matter ratio (GWR) was retrospectively calculated on Swedish subjects with original images available. (lu.se)

A genome examination using 85 informative molecular markers was conducted. (cambridge.org)
The proportion of BC-like polycyclic aromatic structures decreases downstream, but marked spatial variability in abundance and Δ 14 C values of DBC molecular markers imply dynamic sources and cycling in a manner that is incongruent with bulk DOC. (nature.com)

Introduction The research of Hatch (1) has greatly increased our understand- ing of the use and potential limitations of biological markers for adverse reproductive effects. (cdc.gov)
Exposure to a potential fetal health hazard can be estimated through ecological assessment (e.g., testing the community water supply), questionnaires (e.g., classifying residents accord- ing to whether they drink bottled or tap water), or biological markers (e.g., testing for exposures to chemicals or solvents found in tap water). (cdc.gov)
To date, such biological markers have not been widely available nor have they been widely used when they are available. (cdc.gov)

Results Impression cytology specimens from normal and diseased ocular surfaces showed distinct expression patterns for K12 and MUC1. (bmj.com)
We also found that SRC-3 depletion in cultured HESCs results in a significant attenuation in the induction of a wide-range of established biomarkers of decidualization, despite exposure of these cells to a deciduogenic stimulus and normal progesterone receptor expression. (frontiersin.org)
B lymphocytes and B-cell activating factor promote collagen and profibrotic markers expression by dermal fibroblasts in systemic sclerosis. (ox.ac.uk)
We therefore investigated the involvement of B cells and BAFF in the expression of collagen and profibrotic markers by dermal fibroblasts. (ox.ac.uk)
RESULTS: Coculture of blood B cells and dermal fibroblasts isolated from SSc patients induced IL-6, TGF-β1, CCL2, and collagen secretion, as well as Alpha-SMA, TIMP1, and MMP9 expression in dermal fibroblasts. (ox.ac.uk)

What we are measuring is PCR, which is fine, but it's time consuming," said James Dear, a reader in pharmacology at the University of Edinburgh and paper coauthor, whose work is related to investigating the use of miRNA biomarkers, such as miRNA-122, that are associated with liver toxicity, particularly those resulting from the overuse of acetaminophen. (genomeweb.com)

Qualitatively p53 is not a specific marker for malignancy of oral epithelium. (bvsalud.org)

A primary injury results from the initial anatomic and physiologic insult, which is usually direct trauma to the head, regardless of cause. (medscape.com)
Are Anatomic Results Influenced by WEB Shape Modification? (ajnr.org)
Moreover the "compression" phenomenon has been reported and seems to be associated with poor anatomic results. (ajnr.org)
Anatomic results were not worse in case of WEB shape modification. (ajnr.org)

As a result, it is hard to accurately acquire quantitative criteria with the existing heuristic image processing-based segmentation algorithms. (nature.com)

Linkage was assessed by using five quantitative phenotypes, including a composite measure of reading performance and four component phenotypes. (nih.gov)
Maximal linkage converged at marker D6S1554 across phenotypes. (nih.gov)

These findings were confirmed with results from haplotype studies. (nofima.no)

To define relevant morphological features, 27 quantitative features were extracted and further refined by a novel coefficient of variation feature refinement method in accordance with filter-type feature selection. (springer.com)
This variation on the methodology evolved as the need for more accurate results required more detailed quantitation of the material produced. (persistencemarketresearch.com)

A secondary injury results from hypotension , hypoxia, acidosis, edema, or other subsequent factors that can secondarily damage brain tissue. (medscape.com)

Collectively, our results support SRC-3 as an important coregulator in HESC decidualization. (frontiersin.org)
Collectively, these results identify a novel role for SOX9 as a potential therapeutic marker for the prevention and treatment of NPC. (cancerindex.org)

Internalization of antibodies by specific (target mediated) or non-specific (e.g. pinocytosis in endothelial cells) mechanisms forms a key determinant of the half-life in the body, and even subtle changes to the structure of monoclonal antibodies can result in considerable changes to the duration of activity. (news-medical.net)
Although many related studies have been performed, differences in cell lines, experimental conditions and downstream mechanisms have generally resulted in contradictory findings. (nature.com)

Two statistical approaches were applied to estimate the marker effects and to evaluate their statistical significance: Least Squares (regression) and Maximum Likelihood (ML). The Maximum Likelihood approach was found to be more robust with far fewer false positive trait-marker associations than the Least Square (regression) method. (usda.gov)

Single cells in these populations exhibit different com- stem cell differentiation, Shannon information binations of regulator activity that suggest the presence of multiple theory, entropy configurations of a potential differentiation network as a result of multiple entry points into the committed state. (lu.se)

If repeated measurements of tumor marker are needed, some clinical testing laboratories provide a special reporting mechanism, a serial monitor that links test results and other data pertaining to the person being tested. (wikipedia.org)
A major driving force in the transformation of MR images from mere pictures into mineable data 2 is attributing physiologically relevant physical parameters to the voxels, namely quantitative MRI (qMRI). (biorxiv.org)
in 1986, based on data from the National Cancer Institute's Surveillance, Epidemiology, and End Results Program, the incidence for HCC was 2.4 per 100,000 population, compared with 55.8 per 100,000 for lung cancer and 50.5 per 100,000 for cancer of the colon and rectum (13). (cdc.gov)

So far, these EEG markers could have a prospective value in differential diagnosis between vascular and degenerative MCI. (hindawi.com)
However, with an adeq battery of necf expsre blmarkers, prospective studies of en- vironmental effects on pregnancy outcomes might be possible. (cdc.gov)

The red cross markers show the result when using LightGBM's default parameters without any tuning. (medium.com)
The results show the higher averages in the spirituality/religion/personal beliefs and social relations domains in the evaluation of quality of life. (bvsalud.org)

Therefore, incorrect test results carry with them the potential to have serious health consequences. (who.int)
Uncertainties exist regarding levels of exposure to methyl mercury from fish consumption and potential health effects resulting from this exposure. (cdc.gov)

The primary sources of exposure for children are lead-laden paint chips and dust as a result of deteriorating lead-based paint. (cdc.gov)
Past estimates of exposure to methyl mercury has been obtained from results of food consumption surveys and measures of methyl mercury in fish. (cdc.gov)
In this example, a biological exposure marker (blood lead-level) was available for classifying mothers according to their exposure to lead. (cdc.gov)

A tumor marker is a biomarker found in blood, urine, or body tissues that can be elevated by the presence of one or more types of cancer. (wikipedia.org)
The use of these tests without understanding their utility has resulted in inappropriate use of tumor marker blood tests, which has resulted in inappropriate over-investigation for cancers. (wikipedia.org)
Furthermore, with this method only a minor fraction of total exosomes could be isolated from blood as deduced from the constant amount of exosomal markers CD63 and TSG101 detected after serial UC of rat blood plasma samples. (nih.gov)
The VeraSTAT-V device measures quantitative levels of IgG in blood to determine whether a sufficient transfer of antibodies have been achieved. (randox.com)
We explore whether levels of brain injury markers in blood could predict the likelihood of HIE on CT. (lu.se)
The results showed that the 3 ABC transporters , particularly ABCC1 (p less than 0.0001), were highly expressed in the blood of CRC patients compared with controls. (bvsalud.org)

During the same liest markers in patients with atherogenic period, 20 healthy age- and sex-matched risk factors (e.g. male sex, ageing, hyper- personnel whose medical records showed tension, diabetes mellitus, smoking, fam- total cholesterol and triglycerides were ily history) in the absence of angiographic within normal levels and who had no car- evidence of atherosclerosis [1]. (who.int)

If misclassification is differential, misleading results in either direction can occur. (cdc.gov)

Significantly altered MiRNAs were then validated in an independent cohort of samples using quantitative (q) RT-PCR. (ecco-ibd.eu)

These predictive bioanalytic results were confirmed by the demonstration that SRC-3 is required for the expansion, migratory and invasive activities of the HESC population, cellular properties that are required in vivo in the formation or functioning of the decidua. (frontiersin.org)

These mice were genotyped for two D10Mit markers. (cdc.gov)

Chemicals and Drugs3

Analytical, Diagnostic and Therapeutic Techniques and Equipment2

Phenomena and Processes3

Disciplines and Occupations1

Trait Loci7

Polymerase Chain Re2

QPCR2

Qualitative3

Immunohistochemistry2

Detection3

Traits6

Genes5

Assay2

Fluorescence1

Genetic6

Tumors1

Surrogate marker2

Serologic markers2

Viral load2

Analyses2

Analysis9

Microscopic1

Serum3

Methods2

Protein2

Macrophage2

Laboratory3

Imaging4

Measurement1

Inflammation1

Upregulation3

Conclusions3

Study7

Proteins2

0.011

Cytokine2

Retrospectively2

Molecular markers2

Biological markers3

Expression5

Biomarkers1

Qualitatively1

Anatomic4

Accurately1

Linkage2

Haplotype1

Variation2

Subsequent1

Collectively2

Mechanisms2

Approaches1

Differentiation1

Data3

Prospective2

Show2

Potential2

Exposure3

Blood6

Levels1

Differential1

Samples1

Vivo1

Mice1