Quadrivalent meningococcal vaccine. Medical search. Frequent questions

The development of quadrivalent protein-polysaccharide conjugate vaccines against serogroups A, C, W135 & Y offers the possibility of broader protection against the organism across all age groups. (ox.ac.uk)
Current safety issues with quadrivalent meningococcal conjugate vaccines. (nih.gov)
The introduction of Haemophilus influenzae type b conjugate vaccines during the 1990s was followed by dramatic decreases both in the incidence of Haemophilus influenzae type b related invasive disease and in nasopharyngeal carriage of the organism. (bmj.com)
The extent of this effect has been influenced by the fact that Haemophilus influenzae type b conjugate vaccines reduce nasopharyngeal carriage and induce herd immunity. (bmj.com)
Based on the success of Haemophilus influenzae type b conjugate vaccines, chemical conjugation has been applied to the development of pneumococcal and meningococcal polysaccharide conjugate vaccines. (bmj.com)
Evidence has begun to accumulate that these new polysaccharide based conjugate vaccines can also reduce nasopharyngeal carriage and can induce immune responses at the local mucosal level, which may be responsible for these effects. (bmj.com)
A variety of routine childhood and adolescent meningococcal vaccination programs using monovalent (serogroup C) and quadrivalent (A, C, Y, W) conjugate vaccines have been implemented in Canada since 2002, resulting in a decrease in invasive meningococcal disease (IMD) incidence, particularly in serogroup C. Meningococcal vaccines have also been used for outbreak response, including the multicomponent vaccine serogroup B vaccine. (canada.ca)
Since the early 2000s, a variety of routine childhood and adolescent vaccination programs using monovalent (serogroup C) and quadravalent (serogroup A, C, Y and W-135) meningococcal conjugate vaccines have been implemented in Canada Footnote 3 . (canada.ca)
While MenACWY-D and three other quadrivalent meningococcal conjugate vaccines targeting serogroups A, C, W, and Y have been licensed and prequalified by the WHO, supply and cost-constraints have limited their use, Clarke and fellow researchers explained. (medpagetoday.com)
A powerful feature that contributes to the remarkable effectiveness of the MenAfriVac vaccine and other bacterial meningitis conjugate vaccines introduced in large-scale campaigns is the reduction of human-to-human respiratory transmission of encapsulated N. meningitidis and the induction of herd protection among unvaccinated persons," he wrote in an accompanying editorial . (medpagetoday.com)
Updated recommendations regarding quadrivalent meningococcal conjugate vaccines. (hiv.gov)
Novel conjugate vaccines may provide benefits for the community by reduction of carriage. (who.int)
These experts discussed the importance of introducing conjugate vaccines for pilgrims and travellers, and elaborated a consensus recommendation to support healthcare professionals and decision-makers. (who.int)
three conjugate vaccines (MCV-4), Menactra, Menveo and MenQuadfi. (roaldbradstock.com)
This article reviews the increasing evidence that MPS vaccination impairs serum anticapsular antibody responses to subsequent injections of MPS or meningococcal conjugate vaccines (antibody hyporesponsiveness). (ox.ac.uk)

A bivalent meningococcal polysaccharide protein conjugate vaccine that provides protection against meningococcal serogroups C and Y along with Haemophilus influenzae type b (Hib) (Hib-MenCY-TT [MenHibrix, manufactured by GlaxoSmithKline Biologicals, Rixensart, Belgium]) is licensed for use in children aged 6 weeks through 18 months. (cdc.gov)
Menveo is designed to prevent invasive meningococcal disease caused by Neisseria meningitides serogroups A, C, Y, and W-135. (genengnews.com)
The study compared the safety and immunogenicity of Menveo against each of the four serogroups it is designed to protect against with the safety and efficacy of the other currently U.S.-licensed ACW-135Y meningococcal conjugate vaccine. (genengnews.com)
Vaccination is used for close contacts of patients with meningococcal disease due to A, C, Y, or W135 serogroups, to prevent secondary cases. (medscape.com)
MenHibrix, a combination vaccine, is a 4-dose sequence approved for use in children as young as 6 weeks old and is indicated for active immunity against invasive disease caused by Neisseria meningitides serogroups C and Y, and Haemophilus influenzae type b. (medscape.com)
Invasive meningococcal disease caused by some serogroups is vaccine preventable and endemic in Canada, with increased activity occurring periodically in the winter months. (canada.ca)
The phase III study included individuals ages 2 to 29 years in Mali and Gambia, the target demographic in outbreak-response campaigns, and the pentavalent vaccine (NmCV-5) elicited similar seroresponse rates across shared serogroups along with favorable geometric mean titer (GMT) ratios versus the licensed vaccine, MenACWY-D (Menactra), according to Ed Clarke, MBChB, of the London School of Hygiene and Tropical Medicine in Banjul, Gambia, and colleagues. (medpagetoday.com)
GMT ratios favored the NmCV-5 vaccine across all serogroups of Neisseria meningitidis , the predominant cause of meningitis epidemics, ranging from 1.7 (95% CI 1.5-1.9) for serogroup A to 2.8 (95% CI 2.3-3.5) for serogroup C, with serogroup X responses also hitting prespecified criteria for noninferiority for both measures. (medpagetoday.com)
The use of meningococcal vaccines that include coverage against serogroups W and Y in immunization programs for older adults needs to be evaluated to inform health authorities' decisions of the relative benefits of vaccination and the utility of expanding national immunization programmes to this age group. (biomedcentral.com)
Current vaccines are directed against some but not all of these serogroups. (msdmanuals.com)
For Hajj pilgrims the quadrivalent vaccination against serogroups A, C, W-135 and Y is a mandatory requirement. (who.int)
Current travel guidelines for preven- iours (e.g. kissing, coughing, smoking) onstrated for serogroups C and W135 tion of meningococcal disease vary from all increase exposure to the bacteria [1]. (who.int)
Serogroups B, C, and Y are the major causes of meningococcal disease in the United States, each accounting for approximately one third of cases. (cdc.gov)
Serogroups C, Y, or W, which are included in vaccines available in the United States, cause 73% of all cases of meningococcal disease among persons aged ≥11 years. (cdc.gov)

Although immunization with the human papillomavirus vaccine is recommended for all boys and girls, vaccination rates remain low. (aafp.org)
The most common adverse effects of the human papillomavirus vaccine are transient and similar to those of other vaccines, including mild pain and bruising at the injection site, headache, lightheadedness, and syncope. (aafp.org)
Three vaccines are routinely recommended for adolescents to prevent pertussis, meningococcal disease, and cancers caused by human papillomavirus (HPV). (medscape.com)
In the United States, the Advisory Committee on Immunization Practices (ACIP) recommends that children aged 11-12 years receive tetanus, diphtheria, and acellular pertussis vaccine (Tdap), meningococcal conjugate vaccine (MenACWY), and human papillomavirus (HPV) vaccine (HPV vaccine can be started at age 9 years). (medscape.com)
A vial of human papillomavirus vaccine. (yahoo.com)
The vaccine for human papillomavirus, or HPV, works best when given to children in late childhood and early adolescence - before they're sexually active - according to some experts. (yahoo.com)
Multilevel Implementation Strategies for Adolescent Human Papillomavirus Vaccine Uptake: A Cluster Randomized Clinical Trial. (mayo.edu)
Human papillomavirus (HPV) vaccination rates are lower than Tetanus-diphtheria-pertussis (Tdap) and Meningococcal conjugate (MenACWY) rates, although the Advisory Committee on Immunization Practices recommends all three vaccines be given routinely at age 11-12. (bvsalud.org)
Many teens are still not getting the recommended vaccines, and fewer parents plan to give their adolescent daughters the human papillomavirus (HPV) vaccine because of concerns about its safety, despite increased clinician recommendations, according to an analysis of data from the 2008-2010 National Immunization Survey of Teens. (neerabhatiaobgyn.com)

ACIP recommends routine vaccination with a quadrivalent meningococcal conjugate vaccine (MenACWY) for adolescents aged 11 or 12 years, with a booster dose at age 16 years. (cdc.gov)
Recommendation of the Advisory Committee on Immunization Practices (ACIP) for Use of Quadrivalent Meningococcal Conjugate Vaccine (MenACWY-D) Among Children Aged 9 Through 23 Months at Increased Risk for Invasive Meningococcal Disease. (cdc.gov)
2010: a study of a new quadrivalent meningococcal (MenACWY) vaccine. (wikipedia.org)
A booster dose of MenACWY is recommended at age 16 years, and using shared clinical decision-making, adolescents and young adults aged 16-23 years may also receive serogroup B meningococcal vaccine (MenB). (medscape.com)
We also examined time series trends of vaccine administration between 2018 and 2023 for HPV initiation at age 9, as well as Tdap, MenACWY and HPV initiation at age 11. (bvsalud.org)
55 years who were vaccinated previously with MenACWY and require revaccination or who may require multiple doses of vaccine. (msdmanuals.com)

Age limits for vaccine administration are based on the risk for potential adverse events (e.g., yellow fever vaccine), lack of efficacy data or inadequate immune response (e.g., influenza vaccine, polysaccharide vaccines), maternal antibody interference and immaturity of the immune system (e.g., measles-mumps-rubella [MMR] vaccine), or lack of safety data. (cdc.gov)
Thimerosal is currently used only in multidose vials of influenza vaccine, and exposure through vaccines is not associated with adverse neurologic outcomes. (aafp.org)
Live attenuated mucosal influenza vaccine has been licensed in the USA, but it will probably be some time before others go into general use. (bmj.com)
and Supemtek (Quadrivalent Influenza Vaccine (recombinant, prepared in cell culture)), for prophylaxis against influenza. (europeanpharmaceuticalreview.com)
Two vaccines recommended during pregnancy in Australia are influenza and pertussis vaccines. (racgp.org.au)
Several vaccines such as haemophilus influenza type B have been used to protect meningitis caused by microorganisms such as hib. (nmmra.org)
In the first incidence of vaccine-associated GBS, surveillance found that 532 of 1,098 patients with a new onset of GBS had recently received an influenza vaccination. (neurologyadvisor.com)
As vaccine safety became increasingly monitored, GBS association with vaccines other than influenza began to be studied. (neurologyadvisor.com)
Compared with previous seasons, in the 2018-2019 influenza season, a VSD analysis 7 found no statistically significant increase in GBS risk with the high-dose influenza vaccine. (neurologyadvisor.com)
Of the 2,831 incidence admissions for GBS, the researchers found that 330 individuals received an influenza vaccine and 109 cases were preceded by influenza infection. (neurologyadvisor.com)
M-001 vaccine is a recombinant protein containing 9 conserved epitopes from Influenza A and B that are common to the vast majority of influenza viruses. (precisionvaccinations.com)
Moderna mRNA-1010 Quadrivalent Influenza Vaccine candidate. (precisionvaccinations.com)
Sanofi's MRT5400 and MRT5401 are mRNA Influenza Vaccine candidates that are entering a phase 1 clinical trial. (precisionvaccinations.com)
MVA-M1+NP vaccine candidate consists of MVA, a replication-deficient pox viral vector that has been safely tested in thousands of patients, to generate a strong immune reaction against Matrix 1 (M1) and Nucleoprotein (NP) influenza antigens. (precisionvaccinations.com)
Live, attenuated influenza vaccine (LAIV) is a nasal spray that can be given to non-pregnant people 2 through 49 years of age. (cdc.gov)
Flu shots include inactivated influenza vaccines (IIV) and recombinant influenza vaccines (RIV). (cdc.gov)
Also known as live, attenuated influenza vaccine (LAIV), this nasal spray contains live viruses. (cdc.gov)
CDC recommends annual influenza vaccination for everyone 6 months and older with any flu vaccine licensed by the Food and Drug Administration (FDA) that is appropriate for the recipient's age and health status. (cdc.gov)
se revisa todos los años y se actualiza, según corresponda, para que coincida con los virus de la influenza en circulación. (cdc.gov)
FDA approved this live attenuated influenza virus (LAIV) nasal spray vaccine for persons 2 through 49 years of age. (cdc.gov)
This is the only cell-based inactivated influenza vaccine that has been licensed by the FDA for using during the 2021-2022 flu season. (cdc.gov)

Meningococcal disease describes the spectrum of infections caused by Neisseria meningiditis, including meningitdis, bacteremia, and bacteremic pneumonia. (cdc.gov)
Meningococcal disease describes the spectrum of infections caused by Neisseria meningitidis , including meningitis, bacteremia, and bacteremic pneumonia. (cdc.gov)
[ 17 ] Current meningococcal vaccines are indicated for active immunization to prevent invasive meningococcal disease caused by Neisseria meningitidis . (medscape.com)
Invasive meningococcal disease (IMD) is a serious illness caused by the bacterium Neisseria meningitidis Footnote 1 . (canada.ca)
Meningococcal Diseases Meningococci ( Neisseria meningitidis ) are gram-negative diplococci that cause meningitis and meningococcemia. (msdmanuals.com)
ABSTRACT The Islamic Hajj to Makkah (Mecca) has been associated with outbreaks of invasive meningococcal disease and the global spread of Neisseria meningitidis serogroup W-135. (who.int)
Meningococcal vaccine refers to any vaccine used to prevent infection by Neisseria meningitidis . (roaldbradstock.com)
Meningococcal vaccines prevent illnesses caused by bacteria called Neisseria meningitidis. (precisionvaccinations.com)

Firm will, however, have to resubmit sBLA for Menveo vaccine in 2-12 month age group. (genengnews.com)
FDA has approved Novartis' quadrivalent meningococcal conjugate vaccine, Menveo®, for use in children from 2-10 years of age. (genengnews.com)
The Menveo vaccine (supplied in a two-vial presentation) for meningococcal groups A, C, Y, and W has been approved in over 60 countries, with more than 72 million doses distributed worldwide since 2010. (gsk.com)
Do not administer Menveo to individuals with a severe allergic reaction (e.g., anaphylaxis) to a previous dose of Menveo , to any component of this vaccine, or to any other diphtheria toxoid-containing vaccine. (gsk.com)

The 4 primary reasons parents gave for not immunizing with MCV4 and Tdap/Td were the same for both vaccines: (1) not recommended, (2) not needed or not necessary, (3) lack of knowledge, and (4) don't know. (neerabhatiaobgyn.com)

According to the lawsuit, Sanofi Pasteur Inc. allegedly engaged in anticompetitive conduct that resulted in inflated prices of the Menactra meningitis vaccine. (hustlermoneyblog.com)
Plaintiffs claim that when they paid for Menactra from Sanofi Pasteur Inc. they had to pay much higher prices than they should have paid for the quadrivalent meningococcal vaccines. (hustlermoneyblog.com)
If you are purchasing Menactra meningitis vaccine, you may be eligible for a potential award by February 20, 2018 ! (hustlermoneyblog.com)
Menactra vaccine contains N meningitidis serogroup 8 A, C, Y and W-135 capsular polysaccharide antigens individually conjugated to diphtheria toxoid 9 protein. (precisionvaccinations.com)

We present results of a planned interim analysis of an ongoing open-label randomised clinical trial in healthy adult volunteers aged 18-70 comparing 2 doses of a conjugate quadrivalent ACWY vaccine one month apart (Group 1) with one dose of a polysaccharide quadrivalent ACWY vaccine (ACWYVax®) followed by one dose of a conjugate quadrivalent ACWY vaccine one month later (Group 2). (ox.ac.uk)

Research by Richard Moxon into the public health impact of Haemophilus influenzae type b (Hib) invasive disease in the UK, and efficacy studies of the Hib conjugate vaccine in UK children, led to the founding of OVG in 1994. (wikipedia.org)
Invasive meningococcal disease (IMD), known as meningitis, is an uncommon but serious illness that can cause life-threatening complications or even death. (gsk.com)
Invasive meningococcal disease is a rare but severe infection in Canada that mostly affects the very young. (canada.ca)
National enhanced case-based surveillance has been conducted in Canada since 1995 through the Public Health Agency of Canada's Enhanced Invasive Meningococcal Disease Surveillance System (eIMDSS). (canada.ca)
Invasive meningococcal disease in older adults in North America and Europe: is this the time for action? (biomedcentral.com)
From December 2016 to February 2017, two cases of invasive meningococcal disease and one case of meningococcal conjunctivitis, all serogroup W, occurred in Aboriginal children in the Ceduna region of South Australia. (who.int)

This report compiles and summarizes all recommendations from CDC's Advisory Committee on Immunization Practices (ACIP) regarding prevention and control of meningococcal disease in the United States, specifically the changes in the recommendations published since 2005 (CDC. (cdc.gov)
ACIP also recommends routine vaccination for persons at increased risk for meningococcal disease (i.e., persons who have persistent complement component deficiencies, persons who have anatomic or functional asplenia, microbiologists who routinely are exposed to isolates of N. meningitidis, military recruits, and persons who travel to or reside in areas in which meningococcal disease is hyperendemic or epidemic). (cdc.gov)
This report compiles and summarizes all recommendations from CDC's Advisory Committee on Immunization Practices (ACIP) regarding prevention and control of meningococcal disease in the United States, specifically the changes in the recommendations published since 2005 ( 1 ), and describes the process undertaken and the rationale used in support of these recommendations. (cdc.gov)
For more information about vaccine-preventable diseases and immunizations required and recommended, please refer to the Centers for Disease Control and Prevention (CDC) , the Advisory Committee on Immunization Practices (ACIP) , the Immunization Action Coalition , and the Department of Health and Human Services . (elon.edu)
ACIP statements on individual vaccines or immune globulins should be consulted for more details on safety and efficacy and on the epidemiology of the diseases. (cdc.gov)
In addition, ACIP recommendations for the remaining vaccines that are recommended for certain or all adults are summarized, as are considerations for catch-up and travel vaccinations and for work restrictions. (cdc.gov)
The mission of CDC and the ACIP members is to sign off on all possible vaccines as safe and effective, and to never turn over any stones that could reveal anything different. (blogspot.com)
For more information, see the Advisory Committee for Immunization Practices' (ACIP) Meningococcal ACIP Vaccine Recommendations and Centers for Disease Control and Prevention (CDC): Meningococcal Vaccination . (msdmanuals.com)
For more information, see also the ACIP's Infant Meningococcal Vaccination: ACIP Recommendations and Rationale . (msdmanuals.com)

or tetanus toxoid, reduced diphtheria toxoid, and acellular pertussis (Tdap) vaccine. (aafp.org)
Tetanus toxoid, reduced diphtheria toxoid, and acellular pertussis vaccine coverage represents coverage with ≥1 Tdap dose at age ≥10 years. (medscape.com)
Students must have a minimum of 3 doses of tetanus/diphtheria vaccine which may include 1 Tdap. (prescottschools.com)
If Tdap has not been previously given, 1 dose of Tdap is required when at least 5 years has passed since the last dose of tetanus-containing vaccine. (prescottschools.com)
Tetanus - reduced diphtheria - reduced acellular pertussis- inactivated polio (Tdap-IPV): The dose at 4-6 years of age is not required if the fourth dose of DTaP-IPV-Hib vaccine was given after the fourth birthday. (gov.mb.ca)
Tdap: (Tetanus, Diphtheria, Acellular Pertussis) 6th grade requires one dose of vaccine. (chathamschools.org)
The Tdap vaccine protects against three serious diseases: tetanus, diphtheria, and pertussis. (hawaii.gov)

[6] Saudi Arabia requires vaccination with the quadrivalent vaccine for international travellers to Mecca for Hajj . (roaldbradstock.com)
With high rates of vaccination with the quadrivalent meningococcal conjugate vaccine in adolescents and college-aged persons, outbreaks of serogroup C and Y disease are rare in this age group. (cdc.gov)

Washington state implemented a provider reminder through its immunization information system (WAIIS) in January 2023 to increase HPV vaccine initiation at 9-years-old by updating the forecasted recommended age for HPV from age 11 to 9. (bvsalud.org)

Guidelines for antimicrobial chemoprophylaxis and for evaluation and management of suspected outbreaks of meningococcal disease also are provided. (cdc.gov)
Meningococcal disease develops rapidly, typically among previously healthy children and adolescents, and results in high morbidity and mortality. (cdc.gov)
Some countries might require coronavirus disease 2019 (COVID-19) vaccine, testing, or both for entry. (cdc.gov)
Several factors influence recommendations for the age at which a vaccine is administered, including age-specific risks for the disease and its complications, age-dependent ability to develop an adequate immune response to a vaccine, and potential interference with the immune response by passively transferred maternal antibodies. (cdc.gov)
Since then OVG has particularly specialised in research into meningococcal disease and vaccines to prevent the disease. (wikipedia.org)
It is also a participant in the UK Paediatric Vaccine Group (UKPVG) and contributes to the Oxford University Hospitals NHS Trust's tertiary Paediatric Infectious Disease and Immunology Service. (wikipedia.org)
Senior staff at OVG are periodically asked to give expert opinions on aspects of vaccines and infectious disease, especially meningococcal disease. (wikipedia.org)
For example the 2015 announcement that 14- to 18-year-olds in the UK are to be vaccinated against MenW disease, and the 2012 European Medicines Agency (EMA) recommendation for approval of a new meningitis B vaccine. (wikipedia.org)
2006: a phase II trial of a new vaccine against MenB disease. (wikipedia.org)
2011 onwards: Ongoing participation in an EU Childhood Life-threatening Infectious Disease Study (EUCLIDS) work package looking at genetic responses to MenC and MenB vaccines. (wikipedia.org)
Meningococcal disease is potentially fatal and always should be viewed as a medical emergency. (medscape.com)
Recent outbreaks of serogroup B meningococcal disease on a few college campuses have heightened concerns for this potentially deadly disease. (medscape.com)
Background information for each vaccine-preventable disease and specific recommendations for use of each vaccine are presented. (cdc.gov)
Serogroup W associated with ST-11 CC is becoming a growing contributor of disease in all age groups not protected by serogroup W-containing vaccines. (canada.ca)
On the basis of these trial data, NmCV-5 may emerge as a tool to support meningococcal disease control, particularly across the meningitis belt of sub-Saharan Africa, and thus may contribute to epidemic elimination and the other goals of the global road map for the Defeating Meningitis by 2030 program ," concluded Clarke and colleagues. (medpagetoday.com)
When vaccination is unavailable especially in cases of strain B meningococcal meningitis, people who are at risk of contracting meningitis as a result of being in close contact with people who are already infected are given antibiotics known as rifampicin to protect them against the disease. (nmmra.org)
The side effects of Bexsero vaccine are usually mild as compared to disease. (drbhole.com)
Leadership Forum (MLF), in Dubai in May 2010 to exchange opinions on meningococcal disease and prevention strategies. (who.int)
Even with antibiotic treatment, about 1 in 10 people with meningococcal disease will die from it. (hawaii.gov)
The meningococcal vaccines protect against some types of bacteria that cause meningococcal disease. (hawaii.gov)
These vaccines are recommended by the Centers for Disease Control and Prevention, the American Academy of Pediatrics, and the American Academy of Family Physicians. (hawaii.gov)
For children aged 2-10 years with underlying diseases associated with increased risk of meningococcal disease, unconjugated meningococcal polysaccharide (MPS) vaccination is still recommended. (ox.ac.uk)
Whether induction of antibody hyporesponsiveness or loss of immunologic memory increase the risk of acquiring meningococcal disease remains speculative. (ox.ac.uk)
However, for children at increased risk of meningococcal disease, immunization with meningococcal quadrivalent conjugate vaccine off-label instead of MPS vaccine should be considered. (ox.ac.uk)
Numerous programs in the US, including Centers for Disease Control and Prevention's (CDC) National Vaccine Adverse Reporting System (VAERS) 4 and the CDC's Vaccine Safety Datalink (VSD) 5 monitor vaccine adverse events. (neurologyadvisor.com)
Measles is a vaccine-preventable disease. (precisionvaccinations.com)
During 2005-2011, an estimated 800-1,200 cases of meningococcal disease occurred annually in the United States, representing an incidence of 0.3 cases per 100,000 population. (cdc.gov)
Approximately 60% of disease among children 0-59 months is caused by serogroup B N. meningitidis , which is not prevented by currently licensed vaccines. (cdc.gov)
however, outbreaks of meningococcal disease continue to occur. (cdc.gov)
Several recent outbreaks of serogroup B meningococcal disease on college campuses highlight the challenge of control of serogroup B meningococcal disease. (cdc.gov)
Surveillance for meningococcal disease is needed to monitor trends in disease incidence, changes in epidemiology and serogroup distribution, and the effect of vaccination on the incidence of disease. (cdc.gov)
5 meningococcal disease (IMD). (who.int)

3 The fourth dose of the diphtheria and tetanus toxoids and acellular pertussis (DTaP) vaccine is associated with an increased incidence of fever and injection site reactions compared with the first dose (one in four children). (aafp.org)
Diphtheria - tetanus - acellular pertussis- inactivated polio- Haemophilus influenzae type b (DTaP-IPV-Hib): Four doses required of a DTaP-IPV-containing vaccine. (gov.mb.ca)
Vaccine errors threaten to undermine the protection immunizations provide and often leave patients inadequately protected against serious diseases such as hepatitis A and B, pertussis, diphtheria, cervical cancer, and many others. (ismp.org)

This article reviews recent studies on mucosal immune responses induced by polysaccharide based vaccines and some protein vaccine antigens against several pathogenic nasopharyngeal bacteria, and discusses the mechanisms and functions of these immune responses that may help our understanding of mucosal immune responses to both immunisation and infection. (bmj.com)
Recent studies show that parenterally administered capsular polysaccharide (PS) based vaccines can induce mucosal immune responses. (bmj.com)
To be effective against colonisation, vaccines must induce local immune responses, which promote elimination of the pathogen, break the chain of transmission, and induce herd immunity. (bmj.com)
Conjugate vaccine technology, where a polysaccharide antigen is coupled chemically to a protein carrier, either by direct linkage or by indirect coupling via diamino spacer molecules, can render the PS specific immune response T cell dependent. (bmj.com)
The final section contains summary tables on the use of vaccines and immune globulins, arranged by immunocompromising condition. (cdc.gov)
Another vaccine to control pneumococcal meningitis is given to people with head injuries and immune deficiencies. (nmmra.org)
Overview of Immunization Immunity can be achieved Actively by using antigens (eg, vaccines, toxoids) Passively by using antibodies (eg, immune globulins, antitoxins) A toxoid is a bacterial toxin that has been modified. (msdmanuals.com)
The patients suffering from immune-suppression may not show adequate level of response to this vaccine. (drbhole.com)
However, regarding vaccine-associated GBS, the mechanism could potentially involve similar immune patterns during vaccine-induced autoimmunity. (neurologyadvisor.com)
11 Those with severe immunosuppression may have a diminished immune response to the vaccine. (hiv.gov)
Moderna Inc. mRNA-1647 vaccine is designed to produce an immune response to both pentamer and gB antigens to prevent CMV infection. (precisionvaccinations.com)

The measles, mumps, and rubella vaccine is not associated with autism. (aafp.org)
The measles, mumps, and rubella vaccine does not increase the risk of autism and should be routinely used. (aafp.org)
M-M-R II vaccine is also known as Measles, Mumps, and Rubella Virus Vaccine Live, is a live virus MMR vaccine. (precisionvaccinations.com)

Diffuse petechiae and purpura in a lethal meningococcal infection. (mhmedical.com)
EXPERT OPINION: First generation (radiation-attenuated) PfSPZ vaccines are safe, well tolerated, 80-100% efficacious against homologous controlled human malaria infection (CHMI) and provide 18-19months protection without boosting in Africa. (cdc.gov)
Meningococcal infection can be very serious, even deadly. (hawaii.gov)
Moderna's mRNA-1944 vaccine candidate targets Chikungunya infection. (precisionvaccinations.com)

If first-year college students aged ≤ 21 years received only 1 dose of vaccine before their 16th birthday, they should be given a booster dose before enrollment. (msdmanuals.com)

To help parents decide when to travel with an infant or young child, advise them that the earliest opportunity to receive routinely recommended immunizations in the United States (except for doses of hepatitis B vaccine at birth and age 1 month) is when the baby is 6 weeks old. (cdc.gov)
To complete a vaccine series before travel, doses can be administered at the minimum ages and dose intervals. (cdc.gov)
Inform parents that infants and children who have not received all recommended vaccine doses might not be fully protected. (cdc.gov)
Methods & Results Sixty participants were immunised with two doses of vaccine at days 0 and 28. (ox.ac.uk)
Conclusions Two doses of conjugate vaccine generate larger memory responses than conjugate vaccine preceded by polysaccharide vaccine. (ox.ac.uk)
Safety Monitoring of Bivalent COVID-19 mRNA Vaccine Booster Doses Among Persons Aged ≥12 Years - United States, August 31-October 23, 2022. (nih.gov)
With no DTaP-IPV vaccine available in Canada, DTaP-IPV-Hib is to be used for all doses. (gov.mb.ca)
Any combination vaccine with IPV requires four doses. (chathamschools.org)
Immunogenicity of two paediatric doses of monovalent hepatitis B or combined hepatitis A and B vaccine in 8-10-year-old children. (vakciny.net)

It works to enhance the understanding of immunity, studies the epidemiology of infectious diseases, and conducts clinical trials into new and improved vaccines for children and adults. (wikipedia.org)
2006: a study looking at the effectiveness of a new vaccine against the bird flu virus H5N1 in children and adults. (wikipedia.org)
2009: a study comparing the effectiveness of two new vaccines against the swine flu virus H1N1 in children and adults. (wikipedia.org)
Initial FDA clearance for use of the vaccine in adolescents and adults aged 11-55 years was granted in May 2010. (genengnews.com)
Unconjugated PS vaccines have been available for many years and have received some use in adults. (bmj.com)
Bexsero vaccine has been approved for adolescents and young adults of age group above 10 years. (drbhole.com)
All adults and adolescents should get the COVID-19 vaccine regardless of their CD4 count or HIV viral load. (hiv.gov)

Other vaccines such as vaccines against meningococcal meningitis caused by strains A, C, Y and W135 called quadrivalent meningococcal vaccine are recommended for students between the ages of 18 and 25. (nmmra.org)
Pour les pèlerins du Hadj , le vaccin quadrivalent contre les sérogroupes A, C, W135 et Y est obligatoire. (who.int)

2 , 5 Administration of acetaminophen at the time of vaccination or shortly afterward may alleviate some adverse effects, but there may be a decreased antibody response to some vaccine antigens in children who receive antipyretics. (aafp.org)

Meningococcal conjugate monovalent (Men-C-C): One dose at or after 12 months of age. (gov.mb.ca)

Mosquirix RTS,S/AS01 (RTS,S) is an approved recombinant malaria vaccine. (precisionvaccinations.com)
MV-CHIK consists of a recombinant live Schwarz-strain measles-vectored vaccine expressing chikungunya virus structural proteins. (precisionvaccinations.com)
MV-LASV vaccine candidate is a recombinant, live-attenuated, viral vectored vaccine. (precisionvaccinations.com)

ACAM2000 was purchased starting 25 years ago and after the anthrax letters a dose was bought for every American-after the old smallpox vaccine that was stored frozen for decades was destroyed, allegedly to save money on electricity. (blogspot.com)
The quadrivalent conjugate meningococcal vaccine is a routine childhood vaccination given to adolescents, preferably at age 11 or 12 years, with a booster dose at age 16 years (see CDC: Child and Adolescent Immunization Schedule by Age ). (msdmanuals.com)
MCV: (Meningococcal) All students over the age of 11 years old are required to be vaccinated with a single dose of a quadrivalent meningococcal vaccine. (chathamschools.org)
Bexsero is a single dose Killed cell component purified vaccine. (drbhole.com)
Adult flu vaccine, also used as high dose for seniors. (nortonhealthcare.com)

The Oxford Vaccine Group (OVG) is a vaccine research group within the Department of Paediatrics at the University of Oxford. (wikipedia.org)

For specific immunocompromising conditions (e.g., asplenia), such patients may be at higher risk for certain diseases, and additional vaccines, particularly bacterial polysaccharide vaccines {Haemophilus influenzae type b (Hib), pneumococcal and meningococcal}, are recommended for them. (cdc.gov)

Providers should review adolescent vaccination records, especially among those born in 2008 and those in populations eligible for the Vaccines for Children program, to ensure adolescents are up to date with all recommended vaccines. (medscape.com)
these persons were due for their routine adolescent vaccines in 2020, during the height of the COVID-19 pandemic. (medscape.com)
But I acknowledged that the reason that some are potentially opposed to the HPV vaccine in adolescent girls is that they believe that it sends an implicit signal to those girls that the sexual activity through which they might acquire HPV is permissible. (theincidentaleconomist.com)
There's no association between an adolescent girl getting the HPV vaccine and her engaging in sexual activity. (theincidentaleconomist.com)

In general, live-virus vaccines (MMR, varicella, yellow fever) should be administered on the same day or spaced ≥28 days apart. (cdc.gov)

Not all travel-related vaccines are effective in infants, and some are specifically contraindicated. (cdc.gov)
Immunization schedules for infants and children in the United States do not provide guidance on modifications for people traveling internationally before the age when specific vaccines are routinely recommended. (cdc.gov)
Vaccines are not just for infants. (hawaii.gov)

Family physicians should gather accurate information about the harms and benefits of vaccines to advocate for vaccination and decrease the incidence of vaccine-preventable diseases. (aafp.org)
It is never too late to be immunized against vaccine preventable diseases. (gov.mb.ca)
These vaccines prevent serious, sometimes life-threatening diseases. (hawaii.gov)

Several new mucosal vaccines against respiratory infections are under development. (bmj.com)

The incidence of meningitis due to H. influenzae and N. meningitidis showed a marked reduction after the introduction of the corresponding vaccines in 1998 and 2001 respectively, and S. pneumoniae became the predominant organism after Mycobacterium tuberculosis. (who.int)
L'incidence des méningites dues à H. influenzae et N. meningitidis a marqué une nette réduction après l'introduction des vaccins correspondants en 1998 et 2001 respectivement, et S. pneumoniae est devenu l'organisme prédominant après Mycobacterium tuberculosis. (who.int)

2020 onwards: a vaccine against COVID-19, the Oxford-AstraZeneca COVID-19 vaccine, has been created and approved, and as of 2021 is in worldwide use along several other vaccines such as the Pfizer-BioNTech COVID-19 vaccine. (wikipedia.org)
These FDA-licensed vaccine products are available in the United States for the 2021-2022 flu season. (cdc.gov)
This is the only LAIV nasal spray vaccine available for use during the 2021-2022 season. (cdc.gov)

As children get older, the protection provided by childhood vaccines can wear off. (hawaii.gov)

The VFC program offers vaccines at no cost for children ages 18 years and younger, who are uninsured, underinsured (health insurance does NOT pay for childhood immunizations), Medicaid-eligible, or American Indian or Alaska Native. (hawaii.gov)

Preliminary Findings of mRNA Covid-19 Vaccine Safety in Pregnant Persons. (nih.gov)
Medigen MVC-COV1901 COVID-19 Vaccine is adjuvanted with Dynavax CpG 1018. (precisionvaccinations.com)

This retrospective analysis of reported cases of meningitis in Bahrain aimed to assess the trend in the incidence of bacterial meningitis from 1990 to 2013, before and after the introduction of new vaccines. (who.int)
The changing trend in the etiology of bacterial meningitis points to the need to study vaccination programme modifications, such as pneumococcal vaccine for the adult population, especially high-risk groups. (who.int)
Since the introduction of MenAfrivac vaccine in 2010, there has been a dramatic decrease in NmA cases while other pathogen species and Nm variants including NmW, NmC and Streptococcus pneumoniae have become more prevalent reflecting a greater diversity of bacterial strains causing meningitis epidemics in Africa today. (biomedcentral.com)

This research showed that immunity waned over time, and formed part of the evidence leading to the changes in the UK MenC vaccine schedule in 2013. (wikipedia.org)

The World Health Organization (WHO) has issued temporary vaccination recommendations for residents of and long-term visitors to countries with active circulation of wild or vaccine-derived poliovirus. (cdc.gov)
Other organizations, particularly the Expanded Programme on Immunization of the World Health Organization, have made different recommendations, particularly with respect to the use of oral polio vaccine (OPV) and Bacille Calmette-Guerin (BCG) for immunocompromised persons. (cdc.gov)
The third section discusses each vaccine and how recommendations for use may be altered in immunocompromised persons. (cdc.gov)
This review focuses on the principles underpinning maternal immunisation, the existing recommendations and maternal vaccines in development, a review of vaccines that may be indicated for pregnant women who wish to travel, and safety data on inadvertent administration of live vaccines to pregnant women. (racgp.org.au)

Administering MPS as a probe to assess conjugate vaccine-induced immunologic memory also can extinguish subsequent memory anticapsular antibody responses, whereas conjugate vaccination regenerates memory B cells. (ox.ac.uk)

mRNA-1653 is a combination vaccine that consists of two distinct mRNA sequences encoding the fusion (F) proteins of hMPV and PIV3 formulated in Moderna's proprietary lipid nanoparticle (LNP) technology. (precisionvaccinations.com)

Quadrivalent meningococcal polysaccharide vaccine (MPSV4 [Menommune, manufactured by sanofi pasteur, Inc., Swiftwater, Pennsylvania]) is the only vaccine licensed for use among persons aged ≥56 years. (cdc.gov)

Meningococcal vaccination is required for travelers entering Saudi Arabia for Umrah or the annual Hajj pilgrimage. (cdc.gov)

A highly immunogenic trivalent T cell receptor peptide vaccine for multiple sclerosis. (vakciny.net)
CONCLUSIONS: The trivalent TCR peptide in IFA vaccine represents a significant improvement in immunogenicity over previous TCR peptide vaccines and warrants investigation of its ability to treat MS. (vakciny.net)

Bexsero vaccine works as active immunization. (drbhole.com)

OVG came to public prominence in 2020 for the vaccine it created to combat COVID-19. (wikipedia.org)

Requirements for licensure of new glycoconjugate vaccines that include performing comparative clinical trials to demonstrate noninferiority with MPS vaccine, or use of a MPS challenge to assess conjugate-induced immunologic memory also should be modified because there are safer approaches for obtaining the same information. (ox.ac.uk)

The rotavirus vaccine minimally increases the rate of intussusception, whereas other vaccines minimally increase the risk of syncope. (aafp.org)

Incidence of Guillain-Barré Syndrome After COVID-19 Vaccination in the Vaccine Safety Datalink. (nih.gov)

The Group has also carried out research on pneumococcal vaccines, typhoid vaccines and, more recently, new vaccines against Ebola. (wikipedia.org)

The pure polysaccharide vaccine Menomune, MPSV4, was discontinued in the United States in 2017. (roaldbradstock.com)

Such was his follower Gaston Ramon (1886-1963), French veterinarian and immunologist who created 100 years ago first anatoxin for active prevention of diphtheria and later tetanus and thus opened era of anatoxins (toxoids) - vaccines based on toxin molecule devoid of toxic properties, but preserving immunogenicity and antigenic specificity. (bvsalud.org)

Organisms7

Diseases2

Chemicals and Drugs29

Analytical, Diagnostic and Therapeutic Techniques and Equipment4

Phenomena and Processes3

Disciplines and Occupations2

Information Science2

Named Groups1

Health Care4

Conjugate vaccines15

Serogroups14

Human papillomavirus9

MenACWY6

Influenza21

Neisseria8

Menveo4

MCV41

Menactra4

ACWY1

Invasive6

ACIP9

Tdap7

Vaccination with the quadrivalent2

20231

Disease32

Pertussis3

Immune11

Mumps3

Infection4

16th birthday1

Doses9

Adults7

W1352

Antigens1

Monovalent1

Recombinant3

Dose5

Department of Paediatrics1

Haemophilus1

Adolescent4

Live-virus vaccines1

Infants3

Diseases3

Infections1

Meningitidis2

20213

Childhood Vaccines1

Immunizations1

COVID-19 Vaccine2

Bacterial3

Immunity1

Recommendations4

Antibody1

Combination vaccine1

Among persons aged1

Hajj1

Trivalent2

Active immunization1

20201

Glycoconjugate1

Rotavirus1

Safety Datalink1

Pneumococcal vaccines1

MPSV41

Toxoids1