In aerobic organisms, this conversion is catalysed by pyruvate dehydrogenase, also uses thiamine pyrophosphate (TPP) but relies on lipoate as the electron acceptor. (wikipedia.org)
Aldehyde1
This enzyme belongs to the family of oxidoreductases, specifically those acting on the aldehyde or oxo group of donor with an iron-sulfur protein as acceptor. (wikipedia.org)
Class1
The systematic name of this enzyme class is pyruvate:ferredoxin 2-oxidoreductase (CoA-acetylating). (wikipedia.org)
Synthase1
In enzymology, a pyruvate synthase (EC 1.2.7.1) is an enzyme that catalyzes the interconversion of pyruvate and acetyl-CoA. (wikipedia.org)
Synthetase1
Other names in common use include: pyruvate oxidoreductase, pyruvate synthetase, pyruvate:ferredoxin oxidoreductase, pyruvic-ferredoxin oxidoreductase. (wikipedia.org)
Enzyme that catalyzes1
A ferredoxin-containing enzyme that catalyzes the COENZYME A -dependent oxidative decarboxylation of PYRUVATE to acetyl- COENZYME A and CARBON DIOXIDE . (bvsalud.org)
Metabolism2
This enzyme participates in 4 metabolic pathways: pyruvate metabolism, propanoate metabolism, butanoate metabolism, and reductive carboxylate cycle (CO2 fixation). (wikipedia.org)
Notably, proteins involved in pyruvate synthesis decreased in stationary phase, whereas proteins involved in glycogen metabolism, pyruvate catabolism, and end-product synthesis increased in stationary phase. (biomedcentral.com)