Apoptosis Regulatory ProteinsFamilial Mediterranean FeverBH3 Interacting Domain Death Agonist ProteinProto-Oncogene Proteins c-bcl-2bcl-2 Homologous Antagonist-Killer ProteinCaspase 1Cytoskeletal ProteinsApoptosisProto-Oncogene ProteinsMyeloid Cell Leukemia Sequence 1 Proteinbcl-2-Associated X ProteinMembrane ProteinsInflammasomesbcl-Associated Death Proteinbcl-X ProteinProtein Structure, TertiaryNitrophenolsCarrier ProteinsInterleukin-1betaMitochondriaAdaptor Proteins, Signal TransducingCytochromes cMitochondrial MembranesProtein BindingMolecular Sequence DataBiphenyl CompoundsProteinsAmino Acid SequenceHeLa CellsCell LineMutationSignal TransductionFrancisellaColchicineThymocytesArmeniaRNA, Small InterferingCell DeathCell Line, TumorTumor Suppressor ProteinsMice, KnockoutImmunoprecipitationTumor Suppressor Protein p53Two-Hybrid System TechniquesCells, CulturedSulfonamidesRNA InterferenceSequence Homology, Amino AcidTransfectionTubulin ModulatorsProtein IsoformsMice, Inbred C57BLReceptors, Death DomainMitochondrial ProteinsAutophagyCell SurvivalBlotting, WesternCaspasesEnzyme ActivationMicroscopy, FluorescencePiperazinesPeptide FragmentsPhosphorylationBoronic AcidsModels, MolecularInflammationRecombinant Fusion ProteinsMolecular MimicryPyrazinesReverse Transcriptase Polymerase Chain ReactionRecombinant ProteinsAnoikisGenes, bcl-2Interleukin-18Endoplasmic ReticulumMonocytesProtein TransportRNA, MessengerCaspase 9Proteasome InhibitorsUp-RegulationThioglycolatesInterleukin-1Models, BiologicalCaspase 8Caspase InhibitorsAntineoplastic AgentsProteasome Endopeptidase ComplexGene Expression RegulationMice, TransgenicImmunity, InnateFlow CytometryBinding SitesGamma RaysImmunoblottingBase SequenceNeuronsTNF-Related Apoptosis-Inducing LigandCell NucleusMacrophages