• Other names in common use include pyrimidine phosphorylase, thymidine-orthophosphate deoxyribosyltransferase, animal growth regulators, blood platelet-derived endothelial cell, growth factors, blood platelet-derived endothelial cell growth factor, deoxythymidine phosphorylase, gliostatins, pyrimidine deoxynucleoside phosphorylase, and thymidine:phosphate deoxy-D-ribosyltransferase. (wikipedia.org)
  • Other mutations of the proximal pyrimidine box (M2) and one site for the Dof binding (M5) also reduced the GA-induced activities to 48% and 54% of the wild-type sequence, respectively, but the effects were not as marked as seen when GARE was mutated. (wikiversity.org)
  • Information from ICR-170-induced mutations on the structure of the pyrimidine-3 locus in Neurospora . (springer.com)
  • Two homozygous mutations identified in this gene produced large deletions that could cripple the enzyme's structure and function, and are thus causally linked to pyrimidine 5' nucleotidase deficiency and hemolytic anemia. (wikipedia.org)
  • Heterozygous mutations in pyrimidine 5' nucleotidase deficiency may contribute to the large variability in thalassemia phenotypes. (wikipedia.org)
  • A complete nucleotide consists of a nitrogenous base, which is the pyrimidine or purine, a sugar molecule and a phosphate group. (wisegeek.com)
  • Superpositions of dipole states of base pairs consisting of purine (A, G) and pyrimidine (C, T) ring structures play the role of qubits, and quantum communication (coherence, entanglement, non-locality) occur in the "pi stack" region of the DNA molecule. (wordnik.com)
  • From the calculations, a dynamic out-of-plane distortion of the molecule in the 3B1(np*) state, which provides for a coherent description of the results of optical and magnetic-resonance data available for the lowest triplet state of pyrimidine, is deduced. (uva.nl)
  • An example of a molecule that contains pyrimidine is thiamine, which is also known as vitamin B1. (wikipedia.org)
  • Reaction of the former with amidines to give 2-substituted pyrimidines, with urea to give 2-pyrimidinones, and guanidines to give 2-aminopyrimidines are typical. (wikipedia.org)
  • Pyrimidines can be prepared via the Biginelli reaction. (wikipedia.org)
  • A novel method is by reaction of N-vinyl and N-aryl amides with carbonitriles under electrophilic activation of the amide with 2-chloro-pyridine and trifluoromethanesulfonic anhydride: Because of the decreased basicity compared to pyridine, electrophilic substitution of pyrimidine is less facile. (wikipedia.org)
  • 8-Cyanopyrrolo[1,2-a]pyrimidines, the cyano group of which is eliminated when they are heated with phosphoric acid, were obtained by reaction of 2-amino-3-cyanopyrroles with acetylacetone. (springer.com)
  • Pentosyltransferases that catalyze the reaction between a pyrimidine nucleoside and orthophosphate to form a free pyrimidine and ribose-5-phosphate. (curehunter.com)
  • We concluded that agents that will block the purine-uptake and incorporation mechanisms, and pyrimidine antimetabolites, may be important in the chemotherapy of malaria. (ajtmh.org)
  • NCS1 proteins are H+/Na+ symporters specific for the uptake of purines, pyrimidines and related metabolites. (wikipedia.org)