In the Bernthsen acridine synthesis, diphenylamine is condensed with carboxylic acids in the presence of zinc chloride. (wikipedia.org)
Other older methods for the organic synthesis of acridines include condensing diphenylamine with chloroform in the presence of aluminium chloride, by passing the vapours of orthoaminodiphenylmethane over heated litharge, by heating salicylaldehyde with aniline and zinc chloride or by distilling acridone (9-position a carbonyl group) over zinc dust. (wikipedia.org)
These transformations tolerated a broad range of the nucleophilic reagents thus allowing the synthesis of a wide variety of hetero- and carbocyclic compounds including the derivatives of pyridine, pyrimidine, pyrazole, pyran, dioxane, and isoxazole as well as their heterofused derivatives. (researchgate.net)
Essentiality of pyridine Synthesis and medicinal use that include Pyrimidine, Purine, azepines, and their derivatives. (medipdf.in)
Total synthesis of C- 13 2 ,N- 15 -imidacloprid with three stable isotopes in the pyridine ring. (mpg.de)
Derivatives5
Acridines are substituted derivatives of the parent ring. (wikipedia.org)
Acridine and its derivatives can be prepared by many synthetic processes. (wikipedia.org)
Acridine and related derivatives (such as amsacrine) bind to DNA and RNA due to their abilities to intercalate. (wikipedia.org)
Acridine dyes are prepared by condensation of 1,3-diaminobenzene derivatives. (wikipedia.org)
Included are any points of fusion of pyridine with the five-membered ring of indole and any derivatives of these compounds. (umassmed.edu)
Quinoline2
Like the related molecules pyridine and quinoline, acridine is mildly basic. (wikipedia.org)
The pyridine analog is quinoline or isoquinoline. (alchetron.com)
Compounds3
Seven compounds show good activity against single cell line whereas, compounds having a pyridine scaffold showed significant anti‐proliferative activity. (researchgate.net)
Fusion of two benzene rings gives rise to a third large family of compounds, respectively the acridine, dibenzothiophene, carbazole, and dibenzofuran. (alchetron.com)
Likewise, the compounds with two benzene rings fused to the central heterocycle are carbazole, acridine, and dibenzoazepine. (alchetron.com)
C13H9N1
Acridine is an organic compound and a nitrogen heterocycle with the formula C13H9N. (wikipedia.org)
Nitrogen2
Nitrogen as Pyridine in Xylenes manufactured and certified gravimetrically under the guidance of an ISO 9001 quality management system. (asistandards.com)
With four imidazopyridine-containing drugs and one pyrazolopyridine-containing drug on the market, bicyclic pyridines containing ring-junction nitrogen are privileged structures in medicinal chemistry. (chemenu.com)
Dyes4
at one time acridine dyes were popular, but they are now relegated to niche applications, such as with acridine orange. (wikipedia.org)
Several dyes and drugs feature the acridine skeleton. (wikipedia.org)
At one time acridine dyes were commercially significant, but they are now uncommon because they are not lightfast. (wikipedia.org)
Negatively charged red-emitting acridine dyes for facile reductive amination, separation and fluorescent detection of glycans. (mpg.de)
Heterocycle1
Acridine displays the reactions expected of an unsaturated N-heterocycle. (wikipedia.org)
Reaction2
When formic acid is the carboxylic acid, the reaction yields the parent acridine. (wikipedia.org)
Crystals of {[Cu(pydc)(amp)].3H 2 O} n were obtained from the reaction of pyridine-2,6-dicarboxylic acid, 2-aminopyrimidine and Cu(NO 3 ) 2 ·3H 2 O under hydrothermal condition. (biomedcentral.com)
Compound1
In the fused ring system of the title compound, C 32 H 37 NO 4 , the central di-hydro-pyridine ring adopts a flattened boat conformation, the mean and maximum deviations of the di-hydro-pyridine ring being 0.1429 (2) and 0.2621 (2) Å, respectively. (iucr.org)
Orange1
Acridine orange (3,6-dimethylaminoacridine) is a nucleic acid-selective metachromatic stain useful for cell cycle determination. (wikipedia.org)
Structure2
Recently, we also reported a tetrameric water cluster rings in the crystal structure of a new proton transfer system derived from pyridine-2,6-dicarboxylic acid and 2-amino-4-methylpyridine [ 19 ]. (biomedcentral.com)
Crystal structure of complex moiety of the copper complex, {[Cu(pydc)(amp)].3H 2 O} n , (pydc = pyridine-2,6-dicarboxylate ion, amp = 2-aminopyrimidine), was reported by Altin et al. (biomedcentral.com)