• Genetic studies have identified susceptibility loci for infantile hypertrophic pyloric stenosis (IHPS) and molecular studies have concluded that smooth muscle cells are not properly innervated in this condition. (patient.info)
  • Early exposure to oral erythromycin in young infants, particularly in the first two weeks of life, has been associated with the development of hypertrophic pyloric stenosis (HPS). (patient.info)
  • You may find the Pyloric Stenosis article more useful, or one of our other health articles . (patient.info)
  • Pyloric stenosis is a condition that can affect the gastrointestinal tract in babies. (nemours.org)
  • The control and regulation of gastric motility and pyloric sphincter function is a complex system which involves the intrinsic myogenic activity of smooth muscle cells, the interstitial cells of Cajal (pacemaker cells), gastrointestinal hormones (eg, motilin, cholecystokinin and gastrin), the autonomic nervous system and the enteric nervous system. (bmj.com)
  • 0.05) decrease in pyloric muscle thickness, but no significant shortening of the pyloric canal after completion of the atropine treatment. (bmj.com)
  • Pyloric muscle thickness was significantly reduced. (bmj.com)
  • It's possible that high levels of gastrin, a hormone, may lead to the abnormal thickening process that narrows the pyloric canal. (mercola.com)
  • Image of stomach and upper portion of duodenum with anterior wall removed at junction to reveal a stenosed pyloric valve. (smartdraw.com)
  • Pyloric stenosis is a spasmodic narrowing of the opening between the stomach and the duodenum. (britannica.com)
  • A recent nationwide review of pyloric stenosis management with atropine in Japan echoed similar findings - they found that surgical intervention has a higher success rates, minimal complications and shorter duration of hospital stay compared to atropine therapy. (medscape.com)
  • This condition, called pyloric stenosis , may occur at any time in early infancy and usually requires surgical treatment. (britannica.com)
  • The continuing enigma of pyloric stenosis of infancy: A review. (springer.com)
  • The presentation of HPS, characterized by post-prandial nonbilious projectile vomiting and progressive feeding intolerance, begins at 2-4 weeks of age, and pyloric narrowing is maximal at 4-8 weeks of age. (sages.org)
  • Whether the vomiting is projectile or not is often dependent on the progression of the stenosis. (sages.org)
  • http://www.ncbi.nlm.nih.gov/pubmed/17210480?tool=bestpractice.com Pyloric stenosis leads to progressive and projectile vomiting. (bmj.com)
  • If the pyloric olive is felt (see Clinical Details, above), the patient may proceed directly to the operating room without imaging. (medscape.com)
  • This physiological explanation for the development of clinical pyloric stenosis at around 4 weeks and its spontaneous long term cure without surgery if treated conservatively, has recently been further reviewed. (wikipedia.org)
  • Since pyloric stenosis disrupts the digestive process, the most common symptoms are chronic, intermittent vomiting and regurgitation of undigested or partially digested food within one to two hours after eating. (mercola.com)
  • In the past, pyloric stenosis was considered a birth defect. (medhelp.org)
  • Pyloric stenosis is a birth defect. (ahealthyme.com)
  • Rarely, there are peristaltic waves that may be felt or seen (video on NEJM) due to the stomach trying to force its contents past the narrowed pyloric outlet. (wikipedia.org)
  • Antibiotics, such as erythromycin, given to a baby within the first 2 weeks of life may slightly increase his or her chances for developing pyloric stenosis. (medhelp.org)
  • One of those was included in the other systemic review, analysed here, and the second study was published only in abstract form, and the possible association between erythromycin and pyloric stenosis was not discussed. (bestbets.org)
  • Create healthcare diagrams like this example called Pyloric Stenosis in minutes with SmartDraw. (smartdraw.com)
  • Pyloric stenosis is more common in whites of northern European ancestry, less common in African-Americans and rare in Asians. (mayoclinic.org)
  • If your veterinarian suspects pyloric stenosis, he or she will take a detailed history of your pet's symptoms and perform a thorough physical examination, including listening to your pet's lungs with a stethoscope. (mercola.com)
  • Pyloric stenosis occurs in 1 of every 200-300 live births and is four times more common in males. (mn.us)
  • When a baby has pyloric stenosis, this narrowing of the pyloric channel prevents food from emptying out of the stomach. (nemours.org)
  • In other words, a three month old infant within 24 hours of a car accident where the car seat went flying into the dashboard of a vehicle suddenly developed into pyloric stenosis. (medhelp.org)
  • Pyloric stenosis should be suspected in any young infant with severe vomiting. (wikipedia.org)
  • Signs of pyloric stenosis usually appear within three to five weeks after birth. (mayoclinic.org)
  • What Are the Signs of Pyloric Stenosis? (nemours.org)