Peptic ulcerGastritisBacteriaEradicationNSAIDsEthanol induced gastric ulcerProton-pump InhibSmall intestineInfection with Helicobacter pyloriInfectionsAspirinCausative agentBacteriumPatients with gastric ulcersMucosalChronicAssociation between HelicobacterStrainsDiagnosisDuodenal or gastricInflammationInhibitionAntibioticsInflammatoryOccurComplicationsLigation modelAntibiotic resistanceDyspepsiaEndoscopySymptomsEtiological agentAntrumSoresTreatmentIndomethacin-inducedEsophageal ulcerErosionsClinicalRatsCause an ulcerErosive esophagitisTherapiesSystematic reviewStomach and intestinalGastrointestinalAcidHeliobacterBacterial infectionAntimicrobial activityAntibacterialDuodenum
Peptic ulcer27
- The term 'peptic ulcer' refers to those that occur in either the stomach or the first part of the small intestine that leads out of the stomach, called the duodenum. (vic.gov.au)
- 6 By 1952, Revers had tried an extract of licorice with glycyrrhizic acid removed in a patient with peptic ulcer. (naturalmedicinejournal.com)
- For decades, doctors believed that ulcers, or peptic ulcer disease ( PUD ), were caused by eating lots of spicy or highly acidic foods (along with smoking, drinking alcohol, poor eating habits and stress). (howstuffworks.com)
- Stomach ulcers are a type of peptic ulcer disease. (healthline.com)
- Hom (Helicobacter outer membrane) family of OMPs in H. pylori consists of four members (HomA, B, C and D). In the H. pylori genome jhp 0870 open-reading frame (ORF) that codes for HomB outer membrane protein is associated with many stomach diseases and is a novel co-marker for peptic ulcer disease (PUD) 9 , 10 . (nature.com)
- investigated pathogenesis and immunological response caused by HomB protein in clinical patients and 190 H. pylori strain isolated from patients with peptic ulcer disease (PUD) or gastritis were evaluated for the clinical importance of homB . (nature.com)
- 2015). A review on peptic ulcer, International journal of recent advances in Sciences and technology, 2 6-10 (2015). (ufv.br)
- 2017. Peptic ulcer disease and non-steroidal anti-inflammatory drugs. (ufv.br)
- 2015). Diagnosis and Treatment of Peptic Ulcer Disease and H. pylori Infection. (ufv.br)
- Globally, diarrhoea and peptic ulcer are the two commonest gastrointestinal disorders faced by humans. (ijpsonline.com)
- The term peptic ulcer refers to ulcers that occur in the stomach (gastric ulcer) or the first portion of the small intestine (duodenal ulcer). (iherb.com)
- Although symptoms of a peptic ulcer may be absent or quite vague, most peptic ulcers are associated with abdominal discomfort noted 45-60 minutes after meals or during the night. (iherb.com)
- Licorice has historically been regarded as an excellent medicine for peptic ulcer. (iherb.com)
- A peptic ulcer is an erosion in a segment of the gastrointestinal mucosa, typically in the stomach (gastric ulcer) or the first few centimeters of the duodenum (duodenal ulcer), that penetrates through the muscularis mucosae. (msdmanuals.com)
- Helicobacter pylori Infection Helicobacter pylori is a common gastric pathogen that causes gastritis, peptic ulcer disease, gastric adenocarcinoma, and low-grade gastric lymphoma. (msdmanuals.com)
- If H. pylori is eradicated, only 10% of patients have recurrence of peptic ulcer disease, compared with 70% recurrence in patients treated with acid suppression alone. (msdmanuals.com)
- Peptic ulcer occurs at young age with highest incidence between 20-40 years, men are affected more than women. (ijaprs.com)
- If these Acid peptic disorders are not treated in time, it may lead to peptic ulcer, haematemasis, malena and perforation of duodenal ulcer which are common now a day with 50% mortality. (ijaprs.com)
- Though the prevalence of stomach ulcers (peptic ulcer disease (PUD)) has been declining over the years, it still affects many people in the United States and globally. (allieddigestivehealth.com)
- The main types of peptic ulcer disease are gastric and duodenal ulcers. (allieddigestivehealth.com)
- As earlier mentioned, a peptic ulcer could also cause bleeding in the stomach or small intestine due to a broken vessel. (allieddigestivehealth.com)
- If NSAIDs caused the peptic ulcer, youll often be advised on how to reduce or eliminate your use. (stomachguide.net)
- Perforated and bleeding peptic ulcer: WSES guidelines. (medscape.com)
- It can occur anywhere on your body, but most commonly appears as a mouth ulcer or a peptic ulcer. (gpostingfirm.com)
- A peptic ulcer is an open sore that develops on the inside lining of your stomach or the upper part of your small intestine. (gpostingfirm.com)
- The most common symptom of a peptic ulcer is a burning sensation or pain in your stomach between your belly button and breastbone. (gpostingfirm.com)
- The supernatant was to peptic ulcer disease, gastritis and gastric excluded from the study. (who.int)
Gastritis9
- Chronic gastritis is the major cause of human gastric cancer caused by the Gram-negative bacterium Helicobacter pylori . (nature.com)
- Helicobacter pylori has been shown to be the causative agent in chronic-active gastritis, and evidence has almost completely satisfied Koch's postulates for this organisms' pathogenicity in primary duodenal ulcers. (cdc.gov)
- Kyoto global consensus report on Helicobacter pylori gastritis. (medscape.com)
- Helicobacter pylori evolution during progression from chronic atrophic gastritis to gastric cancer and its impact on gastric stem cells. (medscape.com)
- H. pylori is a bacteria associated with the development of many common digestive problems like chronic gastritis, peptic ulcers, or stomach cancers, as it leads to erosion of the mucosal barrier and the stomach wall. (healthnews.com)
- This bacterium causes chronic gastritis and duodenal ulcers, and produces the enzyme urease, which neutralizes gastric acid locally, enabling colonization of the stomach. (biomedcentral.com)
- It has also been implicated in the onset of chronic gastritis and peptic ulcers. (joessciencescorner.net)
- Helicobacter pylori, an infective agent of more than 50% of the world population is prominent to be the main causative factor in the etiologies of chronic, active or type B gastritis, peptic and duodenal ulcer, gastric carcinoma, and mucosa-associated lymphoid tumors. (openmicrobiologyjournal.com)
- This study aimed to detect the presence of Helicobacter in gallstone, gallbladder tissue and bile specimens from subjects with H. pylori -positive gastritis with cholelithiasis. (who.int)
Bacteria16
- Helicobacter pylori - bacteria is thought to be responsible for around 60% of stomach ulcers and at least 90% of duodenal ulcers. (vic.gov.au)
- A flourishing crop of H. pylori bacteria can eventually cause ulcers. (howstuffworks.com)
- You may have H. pylori bacteria living in your stomach or duodenum right now and not realize it. (howstuffworks.com)
- HomB protein contributes to the colonization and persistence of H. pylori , and the presence of homB genes affects the number of bacteria adhering to the host cells. (nature.com)
- The organosulfur compounds of garlic exhibit a range of antibacterial properties such as bactericidal, antibiofilm, antitoxin, and anti-quorum sensing activity against a wide range of bacteria including multi-drug resistant (MDR) strains. (frontiersin.org)
- However, more recently the focus has been on the bacteria Helicobacter pylori and non-steroidal anti-inflammatory drugs (NSAIDs) like aspirin and ibuprofen. (iherb.com)
- These ulcers are commonly caused by H. pylori bacteria which can damage the protective lining of your gut over time, allowing stomach acid to create open sores. (leanfactor.com)
- For H. pylori infections, your doctor will prescribe antibiotics, PPIs, and other medications to fight the bacteria and promote healing. (stomachguide.net)
- As living organisms, probiotics also have adhesion ability, and they can compete with harmful bacteria like H. pylori , which leads to a decreased rate of infection potential. (healthnews.com)
- Probiotics can potentially hinder the growth of H. pylori bacteria by releasing certain substances like short-chain fatty acids and antibacterial compounds. (healthnews.com)
- Infectious ulcers are usually caused by bacteria, viruses, or fungi. (gpostingfirm.com)
- The remedy also breaks up mucus, fights bacteria, and works as an antiviral agent. (southworld.net)
- Indeed scientific studies show that Pelargonnium sidoides extracts are effective against Helicobacter pylori bacteria, the main causative agent of stomach ulcers. (southworld.net)
- Zhao and his team found that two ingredients in dragon's blood blocked the growth of bacteria known to cause stomach ulcers and inflammation that frequently results in upset stomachs. (acs.org)
- Helicobacter pylori existed for a very long time as the etiological agent of ulcers but was not recognized as such, until 1983, when Warren and Marshall went against the scientific ideology of the time and announced that ulcers were caused by bacteria, not stress [ 1 ]. (biomedcentral.com)
- Additionally, H. pylori are carcinogenic bacteria and infection may result in gastric cancer [ 2 ]. (biomedcentral.com)
Eradication12
- Among patients with H. pylori infection and a history of upper gastrointestinal bleeding who are taking low-dose aspirin, the eradication of H. pylori is equivalent to treatment with omeprazole in preventing recurrent bleeding. (nih.gov)
- Omeprazole is superior to the eradication of H. pylori in preventing recurrent bleeding in patients who are taking other NSAIDs. (nih.gov)
- Healing effects of rebamipide and omeprazole in Helicobacter pylori-positive gastric ulcer patients after eradication therapy: a randomized double-blind, multinational, multi-institutional comparative study. (druglib.com)
- We conducted a randomized, double-blind trial to compare the healing effects of rebamipide and the proton-pump inhibitor omeprazole in H. pylori-positive gastric ulcers after H. pylori eradication therapy. (druglib.com)
- METHODS: After completion of 1 week of eradication therapy, 132 patients with H. pylori-positive gastric ulcer were enrolled in 5 Chinese and 4 Korean institutions. (druglib.com)
- The H. pylori eradication rate and ulcer healing rate did not differ between the groups, the latter regardless of eradication outcome. (druglib.com)
- CONCLUSIONS: Rebamipide is as effective as omeprazole in treating of H. pylori-positive gastric ulcer after eradication therapy. (druglib.com)
- Omeprazole is a compound that inhibits gastric acid secretion and is indicated in the treatment of gastroesophageal reflux disease (GERD), the healing of erosive esophagitis, and H. pylori eradication to reduce the risk of duodenal ulcer recurrence. (pharmacycode.com)
- Treatment involves acid suppression, eradication of H. pylori (if present), and avoidance of NSAIDs. (msdmanuals.com)
- Does H pylori eradication explain rising obesity? (medscape.com)
- Koletzko L, Macke L, Schulz C, Malfertheiner P. Helicobacter pylori eradication in dyspepsia: New evidence for symptomatic benefit. (medscape.com)
- Fourth-line rescue therapy with rifabutin in patients with three Helicobacter pylori eradication failures. (medscape.com)
NSAIDs9
- We studied patients with a history of upper gastrointestinal bleeding who were infected with H. pylori and who were taking low-dose aspirin or other NSAIDs. (nih.gov)
- Although most NSAIDs are used primarily for their anti-inflammatory effects, they are effective analgesics and used to treat mild to moderate pain. (medscape.com)
- Anti-inflammatory medications (NSAIDS) are thought to cause around two fifths of stomach ulcers. (vic.gov.au)
- NSAIDs (non-steroidal anti-inflammatory drugs) such as naproxen, ibuprofen or aspirin can also irritate the mucosal lining. (howstuffworks.com)
- H. pylori and nonsteroidal anti-inflammatory drugs (NSAIDs) disrupt normal mucosal defense and repair, making the mucosa more susceptible to acid. (msdmanuals.com)
- There are numerous causes, the most common being Helicobacter pylori (H. pylori) and nonsteroidal anti-inflammatory drugs (NSAIDs). (allieddigestivehealth.com)
- As a result, taking NSAIDs for too long predisposes one to develop ulcers. (allieddigestivehealth.com)
- Using alternatives to NSAIDs, like acetaminophen , to relieve pain can help prevent peptic ulcers. (stomachguide.net)
- The study enrolled 514 H. pylori-negative patients who presented with upper GI bleeding, were on NSAIDs and required concomitant aspirin. (medscape.com)
Ethanol induced gastric ulcer3
- The extract demonstrated protective activity against ethanol induced gastric ulcer lesions in albino rats. (projecttopics.com)
- In the ethanol-induced gastric ulcer model in rats, the lansoprazole (30 mg/kg), FRF and FDF (100 mg/kg) significantly protected the gastric mucosal of rats by 65%, 38% and 25% respectively when compared with the negative control group. (who.int)
- Both EAPA and BPA showed gastric cytoprotective effect in ethanol-induced gastric ulcer and inhibited gastric secretion in pylorus-ligated rats. (jcimjournal.com)
Proton-pump Inhib2
- If your stomach ulcer is the result of H. pylori , you'll need antibiotics and drugs called proton pump inhibitors (PPIs) . (healthline.com)
- Proton pump inhibitors portray the first choice for treating various ulcer diseases, because they inhibits H + /K + -ATpase enzyme by covalently binding to cysteine residue of either potassium or proton pump. (ufv.br)
Small intestine6
- Ulcers can also occur in the lining of the first section of the small intestine, called the duodenum ( duodenal ulcer ), or in the esophagus ( esophageal ulcer ). (howstuffworks.com)
- A small number of people have a congenital defect in their small intestine called Meckel's diverticulum , which causes a small bulge, and ulcers can form there, too. (howstuffworks.com)
- To protect against ulcers, the lining of the stomach and small intestine has a layer of mucin. (iherb.com)
- Modern research has found licorice useful in treating peptic ulcers that may develop in the stomach, lower esophagus, or small intestine. (leanfactor.com)
- Ulcers (peptic) are sores that develop in the lining of the stomach or duodenum (upper small intestine). (allieddigestivehealth.com)
- Peptic ulcers are open sores that develop on the inside lining of your stomach and upper part of your small intestine. (gpostingfirm.com)
Infection with Helicobacter pylori3
- It is uncertain whether infection with Helicobacter pylori is a risk factor for bleeding in such patients. (nih.gov)
- Peptic ulcers caused by infection with Helicobacter pylori are not usually preventable, but good hygiene such as washing your hands thoroughly before eating and after using the bathroom may help limit the spread. (stomachguide.net)
- Infection with Helicobacter pylori is at the top of the list of causes of stomach ulcers. (healthnews.com)
Infections6
- Garlic ( Allium sativum ), a popular food spice and flavoring agent, has also been used traditionally to treat various ailments especially bacterial infections for centuries in various cultures around the world. (frontiersin.org)
- Probiotics are shown to support mucosal barrier integrity, which prevents H. pylori and other kinds of infections. (healthnews.com)
- A meta-analysis study involving 33 different clinical trials with a total of 4,459 patients showed us how adding probiotics to treatments for eradicating H. pylori infections affected the success rates and side effects. (healthnews.com)
- Pharmacological treatment of H. pylori infections includes administration of 3-fold therapeutic regimens which are typically used to suppress H. pylori activity. (openmicrobiologyjournal.com)
- Thus, searching for alternative therapies for H. pylori infections is of special interest. (openmicrobiologyjournal.com)
- Helicobacter pylori infections may lead to gastrointestinal blood loss through ulcer formation. (cdc.gov)
Aspirin6
- Bleeding from stomach ulcers is more common in people treated with blood thinning agents, such as warfarin, aspirin or clopidogrel (Plavix) and those people should also consider using regular anti-ulcer medication to prevent this complication. (vic.gov.au)
- changes to existing medication the doses of arthritis medication, aspirin or other anti-inflammatory medication can be altered slightly to reduce their contributing effects on the stomach ulcer. (stomachguide.net)
- Other causes include non-steroidal anti-inflammatory drugs, such as aspirin and ibuprofen, and stress. (gpostingfirm.com)
- The finding, Bittl and Laine say, "challenges the conventional wisdom that aspirin is the culprit in DAPT responsible for GI injury and raises the possibility that clopidogrel, which does not inhibit COX-1 but targets the P2Y12 receptor, may be ulcerogenic or impair the healing of mucosal injury due to other causes (e.g., nonsteroidal anti-inflammatory drugs or H. pylori ). (medscape.com)
- NEW YORK (Reuters Health) - For patients with a history of upper GI bleeding while taking a non-steroidal anti-inflammatory drug (NSAID) and aspirin who need to continue both drugs, celecoxib with a proton-pump inhibitor (PPI) is "the preferred treatment" to reduce the risk of recurrent GI bleeding, researchers advise based on results of the CONCERN study. (medscape.com)
- The CONCERN study tested whether the COX-2 selective NSAID celecoxib plus a PPI is superior to the non-selective NSAID naproxen plus a PPI for prevention of recurrent ulcer bleeding in concomitant users of aspirin with previous GI bleeding. (medscape.com)
Causative agent2
- Cranberry destroys the causative agent of cholera, E. coli, Helicobacter pylori and is an excellent preventive against stomach ulcers, improves appetite and production of gastric juice, helps to treat the liver. (extract-kit.ru)
- HPV has recently been implicated as the causative agent for cervical cancer. (joessciencescorner.net)
Bacterium9
- Most stomach ulcers are caused by infection with the Helicobacter pylori bacterium or anti-inflammatory medication, not stress or poor diet as once thought. (vic.gov.au)
- However, the Helicobacter pylori ( H. pylori ) bacterium is now known to be responsible for most duodenal ulcers and 60% of stomach ulcers. (vic.gov.au)
- The H. pylori bacterium also prompts many symptoms of indigestion (dyspepsia). (vic.gov.au)
- The Helicobacter pylori bacterium ( H. pylori ) is the main cause of peptic ulcers. (vic.gov.au)
- The vast majority of ulcers are caused by a spiral-shaped bacterium called Helicobacter pylori . (howstuffworks.com)
- The immune system sends white blood cells and other agents to fight the bacterium, but they have a difficult time getting into the lining. (howstuffworks.com)
- Helicobacter pylori is a Gram-negative bacterium that causes chronic inflammations in the stomach area and is involved in ulcers, which can develop into gastric malignancies. (nature.com)
- Researchers at the University of Illinois found that turmeric reduces the inflammation caused by H. pylori, the ulcer-inducing bacterium that's also linked to gastric and colon cancers. (medindia.net)
- The most common cause is an infection with the bacterium Helicobacter pylori. (gpostingfirm.com)
Patients with gastric ulcers2
- In fact, patients with gastric ulcers tend to secrete normal or even reduced levels of gastric acid. (iherb.com)
- is present in 50 to 70% of patients with duodenal ulcers and in 30 to 50% of patients with gastric ulcers. (msdmanuals.com)
Mucosal14
- Amlexanox is a topical mucosal anti-inflammatory agent paste at 5% concentration. (medscape.com)
- BACKGROUND AND AIMS: A recent placebo-controlled trial showed that rebamipide, which is a mucosal-protective antiulcer agent, promoted gastric ulcer healing without affecting the Helicobacter pylori status. (druglib.com)
- Gastric ulcers are essentially sores in the sensitive mucosal lining of the stomach. (howstuffworks.com)
- H. pylori makes its home in the stomach and duodenum, secreting an enzyme that protects it from the onslaught of stomach acid, and then burrows into the mucosal lining. (howstuffworks.com)
- The long-term persistence of H. pylori can stimulate a severe immune response that can damage the mucosal lining. (nature.com)
- Generally it is accepted that gastric ulcers result from an imbalance between aggressive factors and the maintenance of the mucosal integrity through endogenous defense mechanisms. (ijaprs.com)
- Use of synthetic antiulcer drugs may damage to the cell membrane of mucosal, parietal and endothelial cells. (ijaprs.com)
- These medications include mucosal protective agents, which help protect your stomachs mucus lining. (stomachguide.net)
- In the ethanol/HCl-induced ulcer model, lansoprazole (30 mg/kg), EEOH (50, 100, 250 mg/kg) given orally protected the gastric mucosal against injury in mice by 79%, 78%, 73%, and 64% respectively. (who.int)
- Probiotics may help with stomach ulcers by decreasing H. pylori infection due to decreased adhesion capability, providing an antibacterial environment, and improving the mucosal barrier of the stomach. (healthnews.com)
- H. pylori is a gram-negative, microaerophilic, motile rod, with a distinctive spiral shape, and long flagella that assist with both motility and attachment within the stomach mucosal layer. (biomedcentral.com)
- The formation of gastric ulcers is associated with an imbalance between mucosal aggressive factors (e.g. (veterinary-practice.com)
- The stomach is then insufflated with air, which helps to flatten out the mucosal folds and "rounds" the stomach, easing passage of the scope around the greater curvature towards the pylorus. (veterinary-practice.com)
- Aphthous stomatitis, also known as recurrent aphthous ulcers or canker sores, is among the most common oral mucosal lesion physicians and dentists observe. (medscape.com)
Chronic3
- More recent evidence has suggested that chronic H. pylori infection as well as early age of H. pylori -acquisition is a critical precursor to gastric carcinoma. (cdc.gov)
- The gastroprotection and anti-ulcer efficacy of the SIECm (25, 100 and 400 mg/kg, p.o.) were tested using acute (acidified ethanol, piroxicam and water restrain stress), and chronic (acetic acid) experimental ulcer models. (researcher-app.com)
- It prevented against the acute induced ulcerations by enhancing gastroprotection through gastric mucus production, NO modulation, antioxidant, reduced gastric secretion and enhanced chronic ulcers healing process, as shown by reduction/prevention of epithelial and vascular damage, in addition to reduction in leucocyte infiltration. (researcher-app.com)
Association between Helicobacter1
- Association between Helicobacter pylori infection and inflammatory bowel disease: a meta-analysis and systematic review of the literature. (medscape.com)
Strains5
- For example, glycyrrhizin and its derivatives have been shown to effectively kill Helicobacter pylori strains, including those that are clarithromycin-resistant or metronidazole-resistant. (naturalmedicinejournal.com)
- With the agreement of these studies, hom B can be considered as a virulence marker of H. pylori virulent strains. (nature.com)
- The antibiotics selected have antimicrobial activity against most H pylori strains. (medscape.com)
- The components of bismuth-containing therapies have demonstrated in vitro activity against most susceptible strains of H pylori . (medscape.com)
- analyzed the full DNA sequence of 48 H. pylori strains from GenBank ( http://www.ncbi.nlm.nih.gov/genbank/ ) and developed a PCR method that tests for H. pylori by specifically targeting the ureA gene [ 12 ]. (biomedcentral.com)
Diagnosis4
- Diagnosis and treatment will depend on your symptoms and the severity of your ulcer. (healthline.com)
- This assay is intended for use as an aid in the diagnosis of H. pylori infection in persons with gastrointestinal symptoms. (cdc.gov)
- Diagnosis is by endoscopy and testing for Helicobacter pylori . (msdmanuals.com)
- Lehours P. Actual diagnosis of Helicobacter pylori infection. (medscape.com)
Duodenal or gastric2
- Lansoprazole, an acid proton-pump inhibitor similar to omeprazole, is used as an untiulcer drug in the treatment and maintenance of healing of duodenal or gastric ulcers, erosive and reflux esophagitis, NSAID-induced ulcer, Zollinger-Ellison syndrome, and Barrett's esophagus. (pharmacycode.com)
- Specifically, the development of a duodenal or gastric ulcer is a result of some factor damaging the protective factors which line the stomach and duodenum. (iherb.com)
Inflammation3
- A population-based epidemiologic study of Helicobacter pylori infection and its association with systemic inflammation. (medscape.com)
- Tahereh Eteraf-Oskouei at the Biotechnology Research Center, Tabriz University of Medical Sciences, in Iran, states, "Drugs for treating inflammation have serious limitations: corticosteroids suppress tissue growth and suppress the immune response, and the non-steroidal anti-inflammatory drugs are harmful to cells, especially in the stomach. (margokelly.net)
- The most common type of inflammatory ulcer is a Crohn's disease ulcer, which is caused by inflammation of the lining of the digestive tract. (gpostingfirm.com)
Inhibition2
- One of the ways in which apple constituents prevent stomach cancer is through their inhibition of Helicobacter pylori, one of the main infectious agents linked to both ulcer and gastric cancer. (greenmedinfo.com)
- 5. And more… Studies on the health benefits of onions and their unique nutritional properties also have shown possible links to the inhibition of gastric ulcers by scavenging free radicals and by preventing growth of the ulcer-forming microorganism, Heliobacter pylori. (onions-usa.org)
Antibiotics5
- Treatment for stomach ulcers includes the use of antibiotics to kill the infection, and acid-suppressing drugs. (vic.gov.au)
- H. pylori can be difficult to get rid of and require a few different types of antibiotics to clear up the infection. (howstuffworks.com)
- medication including antibiotics, to destroy the H. pylori colony, and drugs to help speed the healing process. (stomachguide.net)
- Most ulcers can be treated with antibiotics and other medications. (gpostingfirm.com)
- Infectious ulcers are treated with antibiotics, antivirals, or antifungals. (gpostingfirm.com)
Inflammatory31
- Anti-inflammatory and immunosuppressive agents are used to treat mucocutaneous lesions and arthritis associated with this disease. (medscape.com)
- These agents modify the body's immune response to diverse stimuli and therefore have anti-inflammatory properties. (medscape.com)
- Methylprednisolone exerts anti-inflammatory effects by suppressing the migration of polymorphonuclear leukocytes and reversing increased capillary permeability. (medscape.com)
- It has anti-inflammatory activity. (medscape.com)
- Examples of metallopharmaceuticals include: bismuth subsalicylate - a mild anti-diarrheal also used in treating peptic ulcers caused by antibiotic-resistant H. pylori cisplatin and carboplatin - platinum containing anticancer agents gold salts such as auranofin - anti-inflammatory for treatment of arthritis silver sulfadiazine - antibacterial zinc pyrithione - antibacterial and antifungal Guo J, Sadler PJ (1999). (wikipedia.org)
- Synthesis and biological evaluation of 1, 3-diaryl pyrazole derivatives as potential antibacterial and anti-inflammatory agents. (ufv.br)
- Health benefits that are associated with the use of garlic are attributed to its anticancer, anti-inflammatory, antifungal, antiviral, and antibacterial activity. (frontiersin.org)
- commonly known as Banaba has been traditionally used to treat various ailments including diabetes and obesity due to its antioxidant and anti-inflammatory efficacies. (bvsalud.org)
- or nonsteroidal anti-inflammatory drug (NSAID) use. (msdmanuals.com)
- The primary active compound in licorice root is glycyrrhizin which endows the plant with its well-known sweet taste, as well as antioxidant, anti-inflammatory, anti-carcinogenic, and antimicrobial properties [2]. (leanfactor.com)
- The antibacterial and anti-inflammatory actions of licorice root can significantly reduce the presence of H. pylori in the gut, allowing the sores to heal and also easing the symptoms [2]. (leanfactor.com)
- As such, licorice root extract has been studied for its anticancer benefits-owing to its numerous antioxidant and anti-inflammatory properties. (leanfactor.com)
- Studies show that turmeric besides being an anti-inflammatory agent, help ease symptoms of arthritis. (medindia.net)
- This is an indispensable tool in the fight against catarrhal, viral, infectious diseases of the upper respiratory tract, since berries have anti-inflammatory, antipyretic, antiviral effects. (extract-kit.ru)
- The anti-inflammatory properties of berries help to alleviate the condition with gout, rheumatic and joint pain. (extract-kit.ru)
- Other common risk factors include long-term use of nonsteroidal anti-inflammatory drugs, stress, or high consumption of stomach-triggering foods like spicy foods, caffeine, and alcohol. (healthnews.com)
- Copaifera malmei Harms (Fabaceae) is a plant that occurs in the central region of Brazil, where the plant's leaves infusion is popularly used to treat gastric ulcer and inflammatory diseases. (researcher-app.com)
- She said it had anti-inflammatory properties. (margokelly.net)
- Multiple medical trials have been conducted using honey as an anti-inflammatory agent. (margokelly.net)
- But honey has an anti-inflammatory action free from adverse side effects. (margokelly.net)
- Certain medications, such as nonsteroidal anti-inflammatory drugs can cause ulcers. (gpostingfirm.com)
- Ulcers are most commonly caused by infection, trauma, or an inflammatory process. (gpostingfirm.com)
- Inflammatory ulcers are usually caused by an autoimmune reaction or an inflammatory process. (gpostingfirm.com)
- Inflammatory ulcers are treated with immunosuppressants, such as corticosteroids, or with biological agents, such as infliximab. (gpostingfirm.com)
- 17) Antioxidant and anti-inflammatory activities of berberine in the treatment of diabetes mellitus. (brettelliott.com)
- Studies have shown quercetin to protect against heart disease and several types of cancer with its antioxidant and anti-inflammatory activities. (onions-usa.org)
- The organosulfur compounds, largely responsible for the taste and smell of onions (and garlic), have shown anti-inflammatory and anti-thrombotic activity. (onions-usa.org)
- It may also provide anti-inflammatory action. (medscape.com)
- Antiulcer assays were performed using the protocols of ulcer induced by non-steroidal anti-inflammatory drugs, ethanol and pylorus ligation. (jcimjournal.com)
- In addition, pathogenic factors such as cagA and vacA produced by H. pylori have been found to produce a pronounced inflammatory reaction within the stomach. (biomedcentral.com)
- Behçet syndrome , systemic lupus erythematosus , and inflammatory bowel disease are systemic diseases associated with oral recurrent aphthous ulcers. (medscape.com)
Occur9
- Ulcers occur in this lining. (vic.gov.au)
- Stomach ulcers occur when digestive acids damage your stomach lining. (healthline.com)
- Stomach ulcers occur when the thick layer of mucus that protects your stomach from digestive juices is reduced. (healthline.com)
- Even though duodenal and gastric ulcers occur at different locations, they appear to be the result of similar mechanisms. (iherb.com)
- Ulcers can occur at any age, including infancy and childhood, but are most common among middle-aged adults. (msdmanuals.com)
- Stomach ulcers (sores in the stomach wall) occur when the stomach acid damages the mucus layer and eats away at the stomach wall. (allieddigestivehealth.com)
- Stomach ulcers occur when the layer protecting the stomach lining from stomach acid breaks down. (stomachguide.net)
- Major aphthae typically present as a single ulcer, but multiple ulcers may occur. (medscape.com)
- The aphthae tend to occur in clusters or crops consisting of 10-100 ulcers. (medscape.com)
Complications2
- Cigarette smoking is a risk factor for the development of ulcers and their complications. (msdmanuals.com)
- Guidelines for prevention of NSAID-related ulcer complications. (qxmd.com)
Ligation model2
- The present study investigated the antiulcer activity of Udumbara Ghanasatwa at two graded doses by pylorus ligation model in rats. (ijpsonline.com)
- Parameters of gastric secretion (volume, pH, total protein, and free and total acidity) were determined by the pylorus ligation model. (jcimjournal.com)
Antibiotic resistance2
- HomB and HomA are the most studied OMPs from H. pylori as they play a crucial role in adherence, hyper biofilm formation, antibiotic resistance and are also associated with severe gastric malignancies. (nature.com)
- Fallone CA. Epidemiology of the antibiotic resistance of Helicobacter pylori in Canada. (medscape.com)
Dyspepsia1
- Modern botanical applications of the herb continue this tradition, with recommendations including the treatment of gastric ulcers, bronchitis, cough, and dyspepsia. (naturalmedicinejournal.com)
Endoscopy2
- If you have an actively bleeding ulcer, you'll likely be hospitalized for intensive treatment with endoscopy and IV ulcer medications. (healthline.com)
- proposed that H. pylori All patients received diagnostic upper to the QIAamp spin column in a 2 present in human bile samples might rep- gastrointestinal endoscopy and gastric mL collection tube were processed ac- resent a risk factor for gallstone formation biopsies were taken to confirm the cording to Qiagen protocol. (who.int)
Symptoms11
- Some stomach ulcers don't produce any symptoms. (vic.gov.au)
- A number of symptoms are associated with stomach ulcers. (healthline.com)
- The severity of the symptoms depends on the severity of the ulcer. (healthline.com)
- Talk with a doctor if you have any symptoms of a stomach ulcer. (healthline.com)
- To diagnose a stomach ulcer, your doctor will review your medical history along with your symptoms and any prescription or over-the-counter medications you're taking. (healthline.com)
- What are the symptoms of an ulcer? (iherb.com)
- Gastric ulcer symptoms often do not follow a consistent pattern (eg, eating sometimes exacerbates rather than relieves pain). (msdmanuals.com)
- This is especially true for pyloric channel ulcers, which are often associated with symptoms of obstruction (eg, bloating, nausea, vomiting) caused by edema and scarring. (msdmanuals.com)
- Small ulcers may fail to show any symptoms. (allieddigestivehealth.com)
- Treatment for gastric and duodenal ulcers depends on the causes and how severe your symptoms are. (stomachguide.net)
- Your doctor may recommend that you take medication even if you don't have any symptoms to prevent an ulcer from developing. (gpostingfirm.com)
Etiological agent1
- Helicobacter pylori ( H. pylori ) colonize the stomach and are considered an etiological agent of gastric cancer. (biomedcentral.com)
Antrum3
- Of the 43 subjects with iron-deficiency anemia, 25 (58.1%) had H. pylori in the antrum. (nih.gov)
- By advancing the scope ventrolateral to the lesser curvature and into the dependant portion of the stomach, the antrum and pylorus will be able to be located. (veterinary-practice.com)
- The presence of H. pylori in antrum biopsies was confirmed by rapid urease test and/or histopathological examination. (who.int)
Sores3
- Stomach ulcers, which are also known as gastric ulcers, are painful sores in the stomach lining. (healthline.com)
- Stomach ulcers, or gastric ulcers, are open sores that develop on the stomach wall. (healthnews.com)
- Mouth ulcers are open sores that develop in the mouth. (gpostingfirm.com)
Treatment16
- Treatment of H. pylori infection was associated with more rapid response to oral iron therapy as compared with the use of iron therapy alone. (nih.gov)
- Their ulcers were healed by daily treatment with 20 mg of omeprazole for eight weeks or longer. (nih.gov)
- These agents are used for topical treatment for aphthae. (medscape.com)
- The discovery of this micro-organism in 1983 revolutionised many aspects of gastroenterology, including the treatment of stomach ulcers. (vic.gov.au)
- 4 Two years later, he published a report on the use of licorice juice in the treatment of duodenal ulcers. (naturalmedicinejournal.com)
- Stomach ulcers may be easily cured, but they can become severe without proper treatment. (healthline.com)
- Treatment will vary depending on the cause of your ulcer. (healthline.com)
- Findings obtained in the study justified the clinical applications of Udumbara Ghanasatwa in the treatment of gastric ulcers and diarrhoea. (ijpsonline.com)
- It is traditionally used for the management of a number of ailments including the treatment of diarrhea, skin rashes, epilepsy, gastroenteritis, cholera, relieving pain during pregnancy and as anti-malaria. (projecttopics.com)
- The results provided some pharmacognostic standards for proper identification of the plant and scientific basis for the traditional use of the leaf in the treatment of ulcer. (projecttopics.com)
- Special diets are now known to have very little impact on the prevention or treatment of stomach ulcers. (stomachguide.net)
- Pharmacological considerations and step-by-step proposal for the treatment of Helicobacter pylori infection in the year 2018. (medscape.com)
- Papastergiou V, Georgopoulos SD, Karatapanis S. Treatment of Helicobacter pylori infection: meeting the challenge of antimicrobial resistance. (medscape.com)
- Treatment of anti-infective-associated pseudomembranous colitis. (mhmedical.com)
- Treatment for an ulcer depends on the underlying cause. (gpostingfirm.com)
- The most widely used and most efficient regimens for eradicating Helicobacter pylori are triple therapies (recommended as first-line treatment) and quadruple therapies (recommended as second-line treatment). (medscape.com)
Indomethacin-induced2
- Anti-Helicobacter pylori and antiulcerogenic activity of Aframomum pruinosum seeds on indomethacin-induced gastric ulcer in rats. (ufv.br)
- EAPA and BPA (100 and 200 mg/kg, p.o.) showed gastric ulcer-healing effect in indomethacin-induced ulcer model, while HAPA (200 mg/kg) and HPA showed no significant antiulcer effect. (jcimjournal.com)
Esophageal ulcer1
- There's also another type of PUD, albeit rare, known as an esophageal ulcer . (allieddigestivehealth.com)
Erosions2
- Recurrent upper GI bleeding within 18 months (the primary outcome) occurred in fewer patients on celecoxib (14 patients, nine gastric ulcers and five duodenal ulcers) than on naproxen (31 patients, 25 gastric ulcers, three duodenal ulcers, one gastric ulcer and duodenal ulcer, and two bleeding erosions). (medscape.com)
- Minor aphthous ulcer: Small superficial oval erosions with yellow pseudomembrane and an erythematous border are evident on the labial aspect of the left lower lip. (medscape.com)
Clinical5
- In other words, approximately 10% of the U.S. population has clinical evidence of duodenal ulcer at some time in their lifetime. (iherb.com)
- AGA clinical practice update on the management of refractory Helicobacter pylori infection: expert review. (medscape.com)
- The subjects positive for H. pylori in dental pulp expressed clinical signs of severe dental caries. (biomedcentral.com)
- The clinical presentation of aphthous ulcers is defined by the number of recurrences and severity of disease. (medscape.com)
- In contrast, complex aphthosis has a severe clinical course, with an almost continuous presence of minor or major ulcers. (medscape.com)
Rats1
- Effects of EAPA and BPA on macroscopic changes in ethanol-induced gastric ulcersResults showed that the rats pretreated with EAPA and BPA at doses of 100 and 200 mg/kg had considerably reduced areas of gastric ulcer formation compared to rats pretreated with only Tween-80 (ulcer control). (jcimjournal.com)
Cause an ulcer2
- While you can rest assured that your love of spicy food won't cause an ulcer, the actual cause might surprise you. (howstuffworks.com)
- How much alcohol can cause an ulcer? (ulcertalk.com)
Erosive esophagitis1
- Lansoprazole is used short-term (4-8 weeks) to treat duodenal ulcer and erosive esophagitis. (pharmacycode.com)
Therapies2
- Randomized controlled trial comparing 7-day triple, 10-day sequential, and 7-day concomitant therapies for Helicobacter pylori infection. (medscape.com)
- Therefore, clinicians have focused on new potential therapies for treating stomach ulcers. (healthnews.com)
Systematic review1
- Rescue therapy with a proton pump inhibitor plus amoxicillin and rifabutin for Helicobacter pylori infection: a systematic review and meta-analysis. (medscape.com)
Stomach and intestinal2
- Rarely, a condition known as Zollinger-Ellison syndrome can cause stomach and intestinal ulcers by increasing the body's production of acid. (healthline.com)
- In addition, the constant renewing of intestinal cells and the secretion of factors which neutralize the acid when it comes in contact with the stomach and intestinal linings also protect against ulcer formation. (iherb.com)
Gastrointestinal1
- Stomach ulcers are a common gastrointestinal problem that need to be treated to avoid severe problems like stomach cancers. (healthnews.com)
Acid9
- Apple cider vinegar, for instance, has been found to contain an anti-tumor compound which results from the acetic acid fermentative process known as alpha-glycan . (greenmedinfo.com)
- The pH of gastric acid (1 to 3) would eat an ulcer right through the skin. (iherb.com)
- Contrary to popular opinion, over-secretion of gastric acid output is rarely a factor in gastric ulcers. (iherb.com)
- In duodenal ulcer patients, almost half have increased gastric acid output. (iherb.com)
- Even with an increase in gastric acid output, under normal circumstances, there are enough protective factors to prevent either gastric or duodenal ulcer formation. (iherb.com)
- Although alcohol is a strong promoter of acid secretion, no definitive data link moderate amounts of alcohol to the development or delayed healing of ulcers. (msdmanuals.com)
- In severe cases, an ulcer that keeps coming back may be treated by surgery to cut off some of the nerve supply to the stomach that produces stomach acid. (ulcertalk.com)
- In pylorus-ligated mice, cimetidine (positive control) and FRF significantly decreased gastric acid secretion, increased gastric pH and reduced the acid output when compared to the negative control. (who.int)
- The therapeutic attributes of Pelargonnium sidoides are due to the various phytochemicals contained in the plant especially the presence of a remarkable series of simple coumarins, phenolic acids, flavonoids, gallic acid and the gallic acid, methyl ester, which greatly contribute to the herb's antibacterial, antifungal, anti-mycobacterial and immuno-modulatory properties which make it highly curative. (southworld.net)
Heliobacter1
- An obvious question related to DGL is "Does DGL have any effect on Heliobacter pylori? (iherb.com)
Bacterial infection1
- The most common cause of stomach ulcers is bacterial infection by Helicobacter pylori . (healthnews.com)
Antimicrobial activity1
- The results showed that Cassia sieberiana exhibited strong antimicrobial activity against H. pylori at two different concentrations of 20, 40mg/mL. (pcbiochemres.com)
Antibacterial5
- The review provides a focused and comprehensive portrait of the status of garlic and its compounds as antibacterial agents. (frontiersin.org)
- In addition, the emerging role of new technologies to harness the potential of garlic as a novel antibacterial agent is discussed. (frontiersin.org)
- PubMed http://www.ncbi.nlm.nih.gov/pubmed/12672149 Investigations into the antibacterial activities of phytotherapeutics against Helicobacter pylori and Campylobacter jejuni. (brettelliott.com)
- Both of the essential oils showed different degrees of antibacterial effect against H. pylori . (openmicrobiologyjournal.com)
- The obtained results showed the antibacterial effect of Shoya powder and Essential oils from Thymus vulgaris and Eucalyptus globulus and purposes new therapeutical alternatives to control the H. pylori infection. (openmicrobiologyjournal.com)
Duodenum4
- If the ulcer becomes deep enough to cause a hole through the wall of your stomach or duodenum, this is a medical emergency and surgery is most often required to fix the problem. (stomachguide.net)
- Ulcers develop when the acids that digest food injure the lining of your stomach or duodenum. (gpostingfirm.com)
- By the end of the day all delegates had managed to conquer the enigma of passing a gastroscope through the pylorus and into the duodenum. (veterinary-practice.com)
- At the entrance to the pylorus the scope can be passed through into the duodenum for further investigation and biopsy collection if indicated. (veterinary-practice.com)