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  • psychogenic purpura
  • Psychogenic purpura (sometimes also referred to as Gardner-Diamond syndrome, autoerythrocyte sensitization, painful bruising syndrome) is a rare and poorly understood clinical presentation of unexplained painful ecchymotic lesions, mostly on the extremities and/or the face. (uptodate.com)
  • The clinical, pathophysiologic, and diagnostic aspects of psychogenic purpura will be discussed here. (uptodate.com)
  • The first publication concerning psychogenic purpura was by Gardner and Diamond in 1955 [ 1 ]. (uptodate.com)
  • Since psychogenic purpura occurs in the psychiatric patient population, factitious bleeding and deliberate self-induced mutilation or other trauma need to be ruled out. (uptodate.com)
  • There are also cases of psychogenic purpura described in the medical literature, [ 2 ] some claimed to be due to "autoerythrocyte sensitization. (thefullwiki.org)
  • Other studies [ 3 ] suggest, that local (cutaneous) activity of tPA can be increased in psychogenic purpura, leading to substantial amounts of localized plasmin activity, rapid degradation of fibrin clots, and resultant bleeding. (thefullwiki.org)
  • coagulation
  • Purpura fulminans is a rare syndrome of intravascular thrombosis and hemorrhagic infarction of the skin that is rapidly progressive and is accompanied by vascular collapse and disseminated intravascular coagulation. (medscape.com)
  • 2001
  • Mahamedi H, André M, Privat C et al (2001) Apport de la tomodensitométrie abdominopelvienne dans le purpura rhumatoïde de l'adulte. (springer.com)
  • Saulsbury FT (2001) Henoch-Schönlein purpura. (springer.com)
  • pathophysiology
  • While three distinct presentations of purpura fulminans are recognized, the underlying pathophysiology stems from a qualitative or quantitative deficiency in protein C, an important regulator of the clotting cascade. (medscape.com)
  • severe
  • Fatome A, Bouin M, Dao T et al (2004) Henoch-Schönlein purpura in an adult revealed by severe gastrointestinal involvement. (springer.com)