QuantificationCannabinoidContaminantsAssurance managerSamplesEvaluationEfficiencyGenesDecisionsApplicationsProcessTemperatureBiomedicalExpressionOrderMethodsHealthcareHealthy controlsHigh-resolutionCriticalSimpleGrowthProteinsAmplificationAmino acidsCenters for DiseasNucleotideSequenceGenomeProteinPharmacokineticsConsistencyCellularStudyGeneticEfficacyLibrariesStudiesLaboratoriesShiftAspectsSystemsPerformanceDataAcceptanceHighSolutionsProvideLargeProperties
Quantification3
- Nucleic acid and protein quantification and purity assessment, the core functions of NanoDrop spectrophotometers, are indispensable for many downstream applications, notably RT-qPCR and quality control. (thermofisher.com)
- You can also input custom oligo sequences and the software will automatically calculate the factor to apply for nucleic acid quantification. (thermofisher.com)
- Validation parameters for establishing robust standardised methods for cannabinoid quantification within Cannabis-based drug forms are critically discussed. (researchgate.net)
Cannabinoid1
- which exhibited low transcriptional activity, especially of genes involved in secondary bile acid biosynthesis and neuroendocrine signaling (i.e., production of neurotransmitters, indoles and ligands for cannabinoid receptors). (biomedcentral.com)
Contaminants4
- With advances in UV-Vis software, researchers can now selectively quantify nucleic acid absorbance in the presence of chemical and nucleic acid contaminants . (thermofisher.com)
- Thermo Scientific Acclaro Intelligence Technology software (standard in our premier NanoDrop One/One C and NanoDrop Eight spectrophotometers) uses full-spectrum data and advanced algorithms to identify common nucleic acid contaminants and provide corrected nucleic acid concentrations. (thermofisher.com)
- Acclaro Sample Intelligence Technology allows the NanoDrop One/One C and NanoDrop Eight Microvolume Spectrophotometers to provide more information about sample quality by identifying common contaminants and delivering true sample concentrations. (thermofisher.com)
- Perfluoroalkyl ether carboxylic acids (PFECAs) are a group of emerging recalcitrant contaminants that are being developed to replace legacy per- and polyfluoroalkyl substances (PFAS) in industrial applications and that are generated as by-products in fluoropolymer manufacturing. (bvsalud.org)
Assurance manager1
- This programme is designed to produce graduate who are employable as an industrial chemist, Quality Assurance Manager etc. (edu.ng)
Samples1
- and the use of STRs improved the chances of profiling poor quality samples. (biomedcentral.com)
Evaluation1
- 1985. Mutagenicity evaluation of phthalic acid esters and metabolites in Salmonella typhimurium cultures. (cdc.gov)
Efficiency2
- This is a significant paradigm shift for pharmaceutical industry which aims to improve efficiency, quality and patient outcomes by utilizing digital solutions and data driven approaches in drug discovery, development, manufacturing, supply chain management and personalized medicine. (ddfsummit.com)
- Although the establishment of a consensus set of core STR loci allows comparisons of profiles across jurisdictions and over time through use of national databases, it may also be simultaneously stifling opportunities for the improvement in the quality and efficiency of the service provided. (biomedcentral.com)
Genes1
- Metagenomic analysis revealed enrichment of genes for antibiotic resistance in gene-corrected subjects relative to healthy controls, likely a result of higher healthcare exposure. (europeanhealthjournal.com)
Decisions2
- This information can help scientists troubleshoot difficult extractions or purifications and make decisions regarding sample use in downstream experiments. (thermofisher.com)
- Physiologically based biopharmaceutics models (PBBM) have been playing an increased role in development decisions as related to formulation changes, spanning both clinical development aspects and drug product quality. (ddfsummit.com)
Applications1
- A treatment process on a pilot scale was designed to produce different water qualities for different applications in industry or agriculture. (iwaponline.com)
Process6
- 1987. Physiologically based pharmacokinetics and the risk assessment process for methylene chloride. (cdc.gov)
- DNA sequencing is the process of determining the nucleic acid sequence - the order of nucleotides in DNA. (wikipedia.org)
- This presentation elaborates on setting an agile and smart quality management systems (QMS) that drive measurable impacts across all building blocks to improve product quality, process reliability and ultimately, efficacy as well as patient safety. (ddfsummit.com)
- A versatile water reuse process was established producing different water qualities (MULTI-ReUse). (iwaponline.com)
- This predestined ultrafiltration as a critical control point for high-resolution process monitoring by online flow cytometry that produced data on total and intact cells in high temporal resolution. (iwaponline.com)
- Offline cytometry allowed the assessment of the change in regrowth potential along the treatment process. (iwaponline.com)
Temperature2
- Temperature was shown to be an important parameter determining the microbiome of the regrown population. (iwaponline.com)
- Detailed instructions on how to equip an OpenSPIM with two illumination sides and two detection axes (X-OpenSPIM) are provided, and a solution is also provided on how the temperature can be controlled in the sample chamber. (mpi-cbg.de)
Biomedical3
- The possibility to record proteomes in high throughput and at high quality has opened new avenues for biomedical research, drug discovery, systems biology, and clinical translation. (elifesciences.org)
- In the natural image domain, spatial embedding-based instance segmentation methods are known to yield high-quality results, but their utility to biomedical data is largely unexplored. (mpi-cbg.de)
- We believe that this renders EmbedSeg accessible to virtually everyone who requires high-quality instance segmentations in 2D or 3D biomedical image data. (mpi-cbg.de)
Expression1
- Recently, it was shown that EP is feasible for reliable decentralized assessment of gene expression. (biomedcentral.com)
Order3
- It includes a detailed analysis of the dynamical behaviour of 1st and 2nd order systems linking behaviour to physical parameters, e.g. (sheffield.ac.uk)
- We will introduce control and feedback as a topic by providing examples of open-loop and closedloop control, and undertake detailed analysis of linear models with a focus on 1st and 2nd order systems. (sheffield.ac.uk)
- The kinetic parameters revealed that the pseudo-second-order model could be used for the description of experimental data rather than the pseudo-first-order model or intraparticle diffusion model. (bvsalud.org)
Methods1
- While many existing computational methods are used to reduce manual labeling time, there is still a huge demand for further quality improvements of automated solutions. (mpi-cbg.de)
Healthcare1
- Obesity is recognized as a complex, multifactorial disease that represents a major risk factor for health, with important consequences on quality of life, life expectancy and healthcare costs [ 3 ]. (biomedcentral.com)
Healthy controls1
- Raman analysis was applied to collect the global signal from the saliva of 23 PD patients and related pathological and healthy controls. (frontiersin.org)
High-resolution1
- Trifluoroacetic acid (TFA), perfluoropropionic acid (PFPrA), and perfluoro-2-methoxyacetic acid (PFMOAA) were confirmed via high-resolution mass spectrometry as transformation products (TPs) in the treated still bottoms, and two distinctive degradation schemes and four reaction pathways are proposed for the four PFECAs. (bvsalud.org)
Critical1
- When setting up downstream reactions such as PCR where DNA concentration is a critical parameter, the corrected concentration will help scientists ensure the success of downstream experiments. (thermofisher.com)
Simple1
- The advantages of this nucleic acid quantitation method are that it is simple, direct, and consumes only a small volume of your sample. (thermofisher.com)
Growth1
- PGPR inoculated okra plants exhibited higher germination percentage, growth parameters, and chlorophyll content than control plants. (hindawi.com)
Proteins4
- It has a genome size of 9.6 kb and encodes a single polyprotein of 3000 amino acids which is further cleaved into 10 proteins by host signal peptidases and viral proteases [ 7 , 8 ]. (biomedcentral.com)
- Discussions focused on progress in high-throughput methods for cloning, production, purification, and crystallization of proteins for X-ray crystallography and NMR studies. (nih.gov)
- The evidence supporting the role of Hsp31-34 in preventing and repairing damage to mitochondria, proteins and nucleic acids by reactive carbonyl species is convincing. (elifesciences.org)
- The structural and functional integrity of nucleic acids and proteins is critical for establishing a physiological balance to maintain normal cellular health. (elifesciences.org)
Amplification1
- This study examined the nucleic acid amplification tests (NAATs) currently used (in 2009) for C. trachomatis detection in laboratories from 17 European countries and five countries/regions outside Europe that are participating in the United Kingdom (UK) National External Quality Assessment Service (NEQAS). (nih.gov)
Amino acids4
- The order of amino acids as they occur in a polypeptide chain. (lookformedical.com)
- The degree of similarity between sequences of amino acids. (lookformedical.com)
- The specific sequence of AMINO ACIDS determines the shape the polypeptide will take, during PROTEIN FOLDING, and the function of the protein. (lookformedical.com)
- A sequence of amino acids in a polypeptide or of nucleotides in DNA or RNA that is similar across multiple species. (lookformedical.com)
Centers for Diseas3
- Centers for Disease Control and Prevention. (cdc.gov)
- Nicole Podnecky was supported by the Emerging Infectious Disease Fellowship Program administered by the Association of Public Health Laboratories and funded by the Centers for Disease Control and Prevention. (cdc.gov)
- B. pseudomallei is recognized as a Select Agent by the Centers for Disease Control and Prevention based on the criteria of infectivity, severity, and environmental prevalence [1] . (cdc.gov)
Nucleotide1
- Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories. (lookformedical.com)
Sequence6
- While these vaccines still require cultivation of the pathogen, the newer generation of vaccines, such as recombinant-protein and nucleicacid vaccines only require the genetic sequence of the pathogen. (technologynetworks.com)
- DNA sequencing is the process of determining the nucleic acid sequence - the order of nucleotides in DNA. (wikipedia.org)
- However, high-quality DNA methylation sequencing has been challenging because poor sequence diversity of the bisulfite-converted libraries severely impairs sequencing quality and yield. (biomedcentral.com)
- A process that includes the determination of AMINO ACID SEQUENCE of a protein (or peptide, oligopeptide or peptide fragment) and the information analysis of the sequence. (lookformedical.com)
- The sequence of PURINES and PYRIMIDINES in nucleic acids and polynucleotides. (lookformedical.com)
- It can be an indication of distant AMINO ACID SEQUENCE HOMOLOGY and used for rational DRUG DESIGN. (lookformedical.com)
Genome1
- The recent years of sequencing efforts have produced high quality genome assemblies from a wide range of species, facilitating genome-wide mapping and annotation of genes. (springer.com)
Protein3
- At this time crystallization was used as a purification tool and allowed James B. Sumner and John H. Northrop to show that the catalytic power of enzymes resides in the protein itself and not in organic catalysts adsorbed on the protein surface. (iucr.org)
- In an effort to facilitate an effective exchange of developments and advancements between pilot centers, the National Institute of General Medical Sciences (NIGMS) organized several workshops on gene cloning, protein expression, and purification. (nih.gov)
- Reactive carbonyl species (RCS) are highly toxic compounds that covalently bind and damage vital cellular components such as protein, DNA, and fatty acids ( Semchyshyn, 2014 ). (elifesciences.org)
Pharmacokinetics2
- 1987. Physiologically based pharmacokinetics and the risk assessment process for methylene chloride. (cdc.gov)
- Careful modification of physicochemical properties of nanocarriers provides improved control over the pharmacokinetics and pharmacodynamics of the encapsulated therapeutic agents relative to free drugs that would typically lead to a superior therapeutic index of the encapsulated agent. (ijpsr.com)
Consistency2
- Taken together, MGISEQ-2000 demonstrated similar data quality, consistency of the methylation levels, comparable analytic sensitivity, and matching clinical performance, supporting its application in future non-invasive early cancer detection investigations by detecting distinct methylation patterns of cfDNAs. (biomedcentral.com)
- Specifications are one part of a total control strategy designed to ensure product quality and consistency. (nih.gov)
Cellular1
- Advances in cellular and molecular biology experimental methods, as well as nucleic acid sequencing technologies, have helped increase our ability to examine the biology of planarians at the molecular level. (biomedcentral.com)
Study1
- Morais, S., Indoor Air Quality Under Restricted Ventilation and Occupancy Scenarios with Focus on Particulate Matter: A Case Study of Fitness Centre. (up.pt)
Genetic1
- Their collective loss stimulates chronic glycation of the proteome, and nucleic acids, inducing spectrum of genetic mutations and reduced mRNA translational efficiency. (elifesciences.org)
Efficacy3
- This presentation elaborates on setting an agile and smart quality management systems (QMS) that drive measurable impacts across all building blocks to improve product quality, process reliability and ultimately, efficacy as well as patient safety. (ddfsummit.com)
- Specifications are chosen to confirm the quality of the drug substance and drug product rather than to establish full characterization and should focus on those molecular and biological characteristics found to be useful in ensuring the safety and efficacy of the product. (nih.gov)
- Gamma-linoleic acid preparations, borage oil, and evening primrose oil show efficacy in small studies. (nih.gov)
Libraries1
- Our scientists are confident in generating high-quality libraries with the diversity of 10 8 . (stratech.co.uk)
Studies3
- A larger variety of case-control studies nor provide a direct quantitative estimate of risk in relation have been performed to research the attainable relationship to radiation dose. (ehd.org)
- The results indicate that knowledge regarding the diversity and function of the defensome will be important for toxicological testing and risk assessment studies. (springer.com)
- cell-culture fermentation, isotopic enrichment with selenium for x-ray crystallography, and/or stable isotopes required for NMR studies, purification, analytical characterization, and growth of x-ray quality crystals. (nih.gov)
Laboratories1
- Laboratories using commercial or in house NAATs that do not detect the nvCT are encouraged to carefully monitor their C. trachomatis incidence, participate in effective internal and external quality assurance and controls schemes, and to consider changing their testing system. (nih.gov)
Shift1
- This is a significant paradigm shift for pharmaceutical industry which aims to improve efficiency, quality and patient outcomes by utilizing digital solutions and data driven approaches in drug discovery, development, manufacturing, supply chain management and personalized medicine. (ddfsummit.com)
Aspects2
- Physiologically based biopharmaceutics models (PBBM) have been playing an increased role in development decisions as related to formulation changes, spanning both clinical development aspects and drug product quality. (ddfsummit.com)
- Hospital Environments - The Relevant Aspects of Indoor Air Quality. (up.pt)
Systems2
- and four automated systems: the MagNAPure LC using the DNA Isolation Kit I, the MagNAPure Compact using the Nucleic Acid Isolation Kit I, and the QIAcube using the QIAamp DNA Mini kit and the QIAamp DNA Blood Mini kit. (cdc.gov)
- This strategy should enable optical and thus remote control or activation of substances inside living systems noninvasively, with a previously unattainable control of depth. (nih.gov)
Performance1
- quality performance to attain excellence in the post-graduate education and research. (pdfslide.us)
Data1
- We sequenced a series of synthetic cell-free DNA (cfDNA) samples with different tumor fractions and found MGISEQ-2000 yielded data with similar quality as NovaSeq6000. (biomedcentral.com)
Acceptance1
- Traditional whole-pathogen vaccine platforms have achieved wide acceptance, but, the newer generation of vaccines, such as nucleic acid vaccines, can significantly accelerate development and manufacturing processes. (technologynetworks.com)
High1
- With years of experience, our scientists can offer high-quality phage display library construction and custom phage display library screening services to meet our clients' demands precisely. (stratech.co.uk)
Solutions1
- Creative Biolabs is committed to providing highly customized comprehensive solutions with the best quality to advance our global clients' projects. (stratech.co.uk)
Provide1
- The prime objective of this University is to provide the learners with quality education in different undergraduate and post graduate programs. (hmamedicalclinic.com)
Large1
- The impact of such remote control is large and broad, allowing previously invasive procedures to be performed noninvasively, and previously inaccessible target sites to be reached for both treatment and diagnosis. (nih.gov)
Properties1
- The arrangement of two or more amino acid or base sequences from an organism or organisms in such a way as to align areas of the sequences sharing common properties. (lookformedical.com)