• Phospholipid content of lavage fluid was determined indirectly by phosphorus assay, and surfactant functional activity was determined by bubble surfactometry. (biomedsearch.com)
  • The survival rate, pulmonary pathology, pulmonary function index of the experimental rats were compared, and the elements in the bronchoalveolar lavage fluid(BALF) were analyzed for its ultrastructure. (cnki.com.cn)
  • METHODS: Seven anesthetized, endotracheally intubated young cats were exposed to periods of CPAP and PAV with the same end-expiratory pressure (0.2-0.5 kPa) before and after lung lavage and after surfactant instillation. (diva-portal.org)
  • In vivo testing was carried out in adult rats made surfactant deficient by repeated lavage and ventilated with 100% oxygen. (elsevier.com)
  • Baritussio A, Bellina L, Carraro R, Possi A, Enzi G, Magoon MW, Mussini J (1984) Heterogeneity of alveolar surfactant in the rabbit: composition, morphology and labelling of subfractions isolated by centrifugation of lung lavage. (springer.com)
  • The aims of this study were to develop a simple and rapid method of nanoparticle dispersion using a natural lung surfactant and to evaluate the effect of dispersion status of SWCNT on cytotoxicity and fibrogenicity in vitro and in vivo . (biomedcentral.com)
  • To aid the investigations of pulmonary responses to nanoparticle exposure, several in vitro and in vivo models have been developed. (biomedcentral.com)
  • Objective To investigate the biological effect of helium-neon laser on the endogenous pulmonary surfactant(PS) and to establish a comprehensive plan for the prevention of pulmonary hemorrhage. (cnki.com.cn)
  • For example, we recently demonstrated that an exogenous surfactant with CATH-2, exhibited antimicrobial activity against antibiotic-resistant bacterial isolates from cystic fibrosis patients, albeit with less efficacy than CATH-2 by itself 5 . (nature.com)
  • Smaller subunits of pulmonary SP-D and the rapid increase of serum SP-D levels in COPD due to exercise support the translocation hypothesis and its use as a COPD biomarker. (biomedcentral.com)
  • Since the lung is the primary route of infection, an understanding of the role of surfactant in defense against C. neoformans could lead to important new therapeutic interventions for both C. neoformans and other fungal infections. (grantome.com)
  • No such association with ARDS or direct pulmonary injury was found for men. (nih.gov)
  • The variant polymorphism of the SP-B gene is associated with ARDS and with direct pulmonary injury in women, but not in men. (nih.gov)
  • Further study is needed to confirm the association between the variant SP-B gene, and gender, ARDS, and direct pulmonary injury. (nih.gov)
  • Lung Epithelial Biology in the Pathogenesis of Pulmonary Disease provides a one-stop resource capturing developments in lung epithelial biology related to basic physiology, pathophysiology, and links to human disease. (elsevier.com)
  • This study may provide a starting point for developing novel ventilation waveforms to improve surfactant function in edematous airways. (biomedsearch.com)
  • Patients that are eligible will be randomized to receive either one dose surfactant or the sham (air) arm after the surgical procedure. (clinicaltrials.gov)
  • As expected, daptomycin was not bactericidal in presence of surfactant at concentrations up to 64 times the MIC. (biomedcentral.com)
  • Interestingly, antimicrobial killing by several antibiotics of Gram-positive S. aureus , but not of Gram-negative P. aeruginosa tended to be faster in presence of surfactant. (biomedcentral.com)
  • These opposite effects on immune cell function by different surfactant components suggest that the relative abundance of various surfactant components in the alveolar lining material determines the functional status of immune cells in the lung. (elsevier.com)
  • The results demonstrate that oligomerization dominantly mediates PR function in different surfactant environments, while some surfactants can subtly modulate proton pumping kinetics. (bioportfolio.com)
  • Human pulmonary mucus samples are collected from the bronchial tubes of patients who have had a lung transplantation or lobectomy surgery (Bichat hospital). (cri-paris.org)
  • This communication presents a physicochemically-based analysis of direct interactions between the basic components of e-liquids (i.e., glycerol (GL) and propylene glycol (PG) that form the aerosol in electronic nicotine delivery systems (ENDS)) and the model pulmonary surfactant: MPS (Survanta). (pmiscience.com)