Pulmonary stretch receptors. Medical search. FAQ

Recent studies have shown that effective pulmonary ventilation is possible with tidal volumes (VT) less than the anatomic dead-space if the oscillatory frequency (f) is sufficiently large. (biomedsearch.com)
It is characterised by an acute exudative phase involving pulmonary oedema and inflammation, which lead to severe hypoxaemia, often necessitating mechanical ventilation. (ersjournals.com)
Maintained inspiratory activity during proportional assist ventilation in surfactant-depleted cats early after surfactant instillation : phrenic nerve and pulmonary stretch receptor activity. (diva-portal.org)
Perfusion of the pulmonary capillaries is closely regulated to match ventilation in order to maximize gas exchange . (amboss.com)
What are the receptors involved in the control of ventilation? (acemprimary.com)
Apparato Respiratorio 4 domande The tubular and cavernous organs and structures, by means of which pulmonary ventilation and gas exchange between ambient air and the blood are brought about. (lookformedical.com)
This sensation arises when pulmonary ventilation is insufficient. (endurance-education.com)
3. With stretch receptors functioning phrenic discharge invariably occurred during the deflation phase of ventilation. (mysciencework.com)

This perception of chest tightness that occurs in bronchoconstriction is stimulated through pulmonary afferents rather than the increased work requirements. (statpearls.com)
Afferents from these receptors (with a high concentration of receptors at the carina) inhibit further inspiration. (anesthesiageneral.com)
The Breuer Hering inflation reflex is initiated by activation of the slowly adapting pulmonary stretch receptor afferents ( SARs ), which monosynaptically activate second-order relay neurones in the dorsal medullary nucleus of the solitary tract (NTS). (manchester.ac.uk)
A substantial part of vagal afferents originates from slow adapting pulmonary stretch receptors (SARs) which induce Hering-Breuer reflexes. (biomedcentral.com)

Patients with COPD and idiopathic pulmonary fibrosis (IPF) have a gradual progression of dyspnea on exertion, punctuated by acute exacerbations of shortness of breath. (wikipedia.org)
My earlier work assessed the role of pulmonary stretch receptors and central chemoreceptors in the genesis and relief of dyspnea or shortness of breath in healthy adults. (bio5.org)
Furosemide also stimulates pulmonary stretch receptors and may relieve dyspnea by duplicating the effects of large tidal volumes. (texasbestremodel.com)
Specific pathologic and age-related changes contribute to pulmonary dysfunction and the experience of dyspnea. (statpearls.com)
2007), and dyspnea triggered by decreased output form pulmonary stretch receptors (Killian, 2006). (apoptosisblog.com)
It is possible , Ischemic wall motion defect per-se can induce myocardial stretch and create a feeling of dyspnea. (drsvenkatesan.com)
Figure: Schematic diagram of the mechanism for dyspnea, demonstrating the interrelationships among ventilatory muscle activity, pulmonary mechanics, breathing effort, and breathing discomfort. (endurance-education.com)
It is well-known pulmonary stretch receptors located in pulmonary vasculature is one of the major mechanism of dyspnea. (drsvenkatesan.com)
It is surprising to note, there is little data on excercise induced pulmonary hypertension in the evaluation of patients with unexplained dyspnea. (drsvenkatesan.com)
Common Causes of dyspnea include anemia , foreign body aspiration , heart failure , pneumonia , pregnancy , and pulmonary edema . (wikidoc.org)
Different causes of dyspnea include pulmonary ( upper and lower airway ), cardiovascular , central nervous system , toxic and metabolic , and systemic diseases. (wikidoc.org)

Stretch receptors are mechanoreceptors responsive to distention of various organs and muscles, and are neurologically linked to the medulla in the brain stem via afferent nerve fibers . (wikipedia.org)
Pulmonary inflation afferent information inhibits pneumotaxic center respiratory activity. (lsuhsc.edu)
His major contribution to the world of Science is the development of a single-fiber technique for recording afferent impulses from individual sensory receptors. (wikipedia.org)
These studies led to studies in the mammalian (rodent) airway that explored the modulation of upper airway muscles activities by chemical and pulmonary afferent feedback and the potential for selective electrical stimulation of the cranial nerve XII to alter airway geometry and volume (NIH/NIDCD RO3). (bio5.org)
M. Sammon and E.N. Bruce, Pulmonary vagal afferent activity increases dynamical dimension of respiration in rats. (springer.com)

The most common cardiovascular causes are acute myocardial infarction and congestive heart failure while common pulmonary causes include chronic obstructive pulmonary disease , asthma , pneumothorax , pulmonary edema and pneumonia . (wikipedia.org)
People with chronic obstructive pulmonary disease (COPD), most commonly emphysema or chronic bronchitis , frequently have chronic shortness of breath and a chronic productive cough. (wikipedia.org)
Chronic diseases such as chronic obstructive pulmonary disease and emphysema can be related to smoking or exposure to harmful substances. (meddic.jp)
The invention relates more specifically to devices and methods for treating conditions associated with bronchial constriction, including: asthma, anaphylaxis, chronic obstructive pulmonary disease (COPD), exercise-induced bronchospasm and post-operative bronchospasm. (justia.com)

The inhibitory effects of CO2 on slowly adapting pulmonary stretch receptors (SARs) were studied before and after administration of acetazolamide, a carbonic anhydrase inhibitor, or nifedipine, a calcium channel blocker, in anesthetized, artificially ventilated rabbits after vagus nerve section. (aspetjournals.org)
We suggest this breathing technique induces inhibition through impulses generated by slowly adapting stretch receptors (SARS), which are derived from the central nervous system during embryonic development [ 17 - 21 ]. (omicsonline.org)
Cough is a phenomenon caused by a reflection mechanism emerges vagal receptors along the respiratory tract have been described three types of receptors, slowly adapting stretch receptors (SARs), rapidly adapting stretch receptors (RARs) and C-fibers. (bvsalud.org)
Several studies have demonstrated that activation of the pump cells by the SARs input is at least partly mediated by the action of glutamate at excitatory amino acid ( EAA ) receptors (most likely of AMPA type) (Bonham et al. (manchester.ac.uk)

1976) suggests that M. pneumoniae infection denude the epithelial surface and expose irritant receptors. (dailystrength.org)
The laryngeal and pulmonary irritant receptors and pulmonary stretch receptors are affected by inhalation agents. (anesthesiageneral.com)

Inhibitory mechanism of CO2 inhalation on slowly adapting pulmonary stretch receptors in the anesthetized rabbit. (aspetjournals.org)
Acetazolamide treatment (20 mg/kg) diminished the inhibitory responses of slowly adapting pulmonary stretch receptors to CO2 inhalation, which were not significantly influenced by pretreatment with nifedipine (1 mg/kg). (aspetjournals.org)
These results suggest that CO2-induced inhibition of slowly adapting pulmonary stretch receptors is not related to the change in bronchomotor tone. (aspetjournals.org)
Local transpulmonary pressure (Ptr) is thought to be closely associated with the activity of slowly adapting pulmonary stretch receptors (SAPSRs). (elsevier.com)
Yang, M. H. / Effects of pulmonary air embolism on discharge of slowly adapting pulmonary stretch receptors . (elsevier.com)

We hypothesized that our model of the central respiratory pattern generator, when appropriately modified to include vagal feedback from the pulmonary stretch receptors, would exhibit chaotic dynamics. (springer.com)
However, signaling of the pulmonary vagal stretch and chest wall receptors can inhibit (and therefore reduce) this sense of air hunger. (statpearls.com)
Unilateral vagal nerve stimulation, in order to simulate activation of the pulmonary stretch receptors, was undertaken. (biomedcentral.com)
It had been hypothesized that the regions of prefrontal cortex which are involved in respiratory control can modulate Hering-Breuer reflexes evoked by vagal input from pulmonary stretch receptors. (biomedcentral.com)

Acute shortness of breath is usually connected with sudden physiological changes, such as laryngeal edema , bronchospasm , myocardial infarction , pulmonary embolism , or pneumothorax . (wikipedia.org)

Pulmonary air embolism (PAE) usually causes small-airway collapse. (elsevier.com)
abstract = "Pulmonary air embolism (PAE) usually causes small-airway collapse. (elsevier.com)

Stimulation of any group of receptors may cause reflex changes in breathing (including defensive reflexes), bronchomotor tone, airway mucus secretion, the cardiovascular system (including the vascular bed of the airways), laryngeal calibre, spinal reflexes and sensation. (biologists.org)
These receptors in turn signal the medullary control centers to increase sympathetic stimulation of the heart, leading to increased heart rate, a.k.a. tachycardia . (wikidoc.org)
Unlike Ach, deltasone davis drug guide succinylcholine produces continuous stimulation of the nicotinic receptor, and the endplate membrane remains depolarized with the channel open. (xaydungdongnam.com)

Cell types only identified in the en bloc medulla included type II and III inspiratory neurons, distinguished by delayed onset and peri-inspiratory inhibition, respectively, and preinspiratory neurons, active before and after but silent during inspiration. (jneurosci.org)
Collectively, these results suggest that the inhibition of adipocyte differentiation in response to stretching is mainly attributable to the reduced expression of PPARγ 2 , which is mediated by activation of the ERK/MAPK system. (biologists.org)
With this syndrome, it has been attributed to the ability to enhance pulmonary stretch receptor activity, inhibition of epiphyseal cartilage development in human adults during parenteral nutrition. (roanokechowan.edu)
Increased pulmonary stretch receptor activity, which leads to inhibition of the nucleus ambiguus, ultimately elevates the heart rate. (wikidoc.org)

The somatic nervous system includes the cranial and spinal nerves and their ganglia and the peripheral sensory receptors. (lookformedical.com)

CO2 inhalation (maximal tracheal CO2 concentration ranging from 7.2% to 9.5%) for approximately 60 sec decreased the receptor activity during both inflation and deflation. (aspetjournals.org)
The magnitude of decreased receptor activity during deflation became more pronounced than that seen during inflation. (aspetjournals.org)
Sulfur dioxide blocks nerve signals from the pulmonary stretch receptors (PSR's) and abolishes the Hering-Breuer inflation reflex. (newworldencyclopedia.org)

For pharmacodynamics of inhaled anesthetics , the pulmonary effects of inhalation agents are many and important as this is the portal of entry. (anesthesiageneral.com)

Abolition of the Breuer-Hering reflex was used as an index of stretch receptor block. (mysciencework.com)

Paintal discovered several sensory receptors including atrial B receptors, pulmonary J-receptors, ventricular pressure receptors, stomach stretch receptors, and muscle pain receptors. (wikipedia.org)

Animals exhibited significant weight loss, decreased oxygenation, increased respiratory elastance and pulmonary inflammation (intra-alveolar leukocyte influx/cytokine levels and histological injury scores). (ersjournals.com)
Reflexes that regulate cardiorespiratory function arise from a wide variety of internal receptors, and include those that signal changes in blood pressure, the level of blood oxygenation, respiratory activity, and metabolic activity. (oxfordre.com)

This results in an increase in the pressure of the right atrium, which stimulates the atrial stretch receptors. (wikidoc.org)
Increasing stretch of the receptors stimulates both an increase in heart rate and a decrease in vasopressin (a.k.a. anti-diuretic hormone ) secretion from posterior pituitary. (wikidoc.org)

It controls the intensity of breathing and is inhibited by the stretch receptors of the pulmonary muscles at maximum depth of inspiration, or by signals from the pnuemotaxic center. (lumenlearning.com)
Muscle spindles in the chest wall signal the stretch and tension of the respiratory muscles. (riograndedonorte.org)

Mechanical stimuli such as stretching and rubbing of fat and skeletal muscle using gymnastic exercises or massage are believed to decrease obesity as well. (biologists.org)
4. Specialized receptors such as those for taste and swallowing, and those around joints and in skeletal muscle. (biologists.org)

In addition, stretching of atrial receptors increases secretion of atrial natriuretic peptide (ANP), which promotes increased water and sodium excretion through the urine. (wikidoc.org)
This is similar to hypertensive response to EST in systemic circulation.Existence of this entity , is controversial, But this may reflect reduced pulmonary vascular reserve or reduced pulmonary nitric oxide secretion. (drsvenkatesan.com)

can respond to mechanical stimuli, including stretching. (biologists.org)
Mechanical receptors: such as pulmonary stretch receptors and J receptors. (senalesforex.com)

A major role of respiratory control comes from pulmonary stretch receptors and their myelinated fibers that give input to our respiratory centers supplementing that from CO 2 , O 2 , pH (measure of the acidity or basicity of a solution) and neurohormonal factors. (spacedoc.com)
B . Cough results from activation of myelinated cough receptors and unmyelinated C-fibers, whose cell bodies are in the jugular and nodose ganglia. (biomedcentral.com)

Risk factors for acute decompensation include high dietary salt intake, medication noncompliance, cardiac ischemia, abnormal heart rhythms , kidney failure , pulmonary emboli, hypertension , and infections. (wikipedia.org)

In this context, we hypothesized that tissue-specific expression of the A2B adenosine receptor is responsible for the previously described attenuation of ALI. (jimmunol.org)
To directly deliver an A2B adenosine receptor-specific agonist to alveolar epithelial cells, we subsequently performed studies with inhaled BAY 60-6583. (jimmunol.org)
Thus, c-fos is induced in rat striatum following administration of caffeine and other xanthines that (provided they enter the brain) block adenosine receptors, suggesting an involvement of central adenosine receptors. (storysteel.tk)

Pulmonary and respiratory tract receptors. (biologists.org)

The apneustic center is inhibited by pulmonary stretch receptors and also by the pneumotaxic center. (wikipedia.org)

Inhaled furosemide offers a potentially novel treatment for dyspnoea, which may reflect modulation of pulmonary stretch receptor feedback to the brain. (brookes.ac.uk)
this is consistent with the notion that modulation of pulmonary stretch receptor feedback by inhaled furosemide leads to dyspnoea relief that is specific to air hunger, the most unpleasant quality of dyspnoea. (brookes.ac.uk)

and trigeminal skin receptors. (statpearls.com)

We know, excercise increases the systemic blood pressure ,we presume it should not raise the PAP (however severe the exertion is 1 )as pulmonary circulation is a high compliant low pressure system. (drsvenkatesan.com)

METHODS: A 17-year-old patient who had sustained blunt thoracic trauma presented with severe hypoxaemia on admission and whole body computed tomography showed pulmonary contusion and substantial bilateral atelectasis. (biomedsearch.com)
His pulmonary investigations of spirometry, chest radiography, chest computed tomography, and endoscopic bronchoscopy were all normal. (rcjournal.com)

4-6 h) of ALI/ARDS [ 6 , 7 ], or use lower acid volume, higher pH and/or unilateral pulmonary instillation to improve survival [ 8 , 9 ]. (ersjournals.com)

Application of cyclic stretching during the entire induction period or only during the final 15 hours of the induction period significantly retarded the induction of glycerol-3-phosphate dehydrogenase (GPDH) activity and the accumulation of intracellular triglycerides by the end of the maturation period. (biologists.org)

These are receptors in the medulla and in the aortic and carotid bodies of the blood vessels that detect changes in blood pH and signal the medulla to correct those changes. (lumenlearning.com)

Cyclomidril eyedrops used to dilate eyes contain cyclopentolate hydrochloride (anticholinergic) and phenylephrine hydrochloride (α 1 -adrenergic receptor agonist). (cancertherapyadvisor.com)

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