• Tropical pulmonary eosinophilia is a rare syndrome characterised by pulmonary interstitial infiltrates and marked peripheral eosinophilia. (wikipedia.org)
  • The Drug Rash with Eosinophilia and Systemic Symptoms (DRESS) syndrome is a severe drug hypersensitivity reaction, notable for skin rash, fever, lymphadenopathy, and involvement of various tissues, such as hepatitis, pneumonitis, or myositis. (medscape.com)
  • Eosinophilia-myalgia syndrome (EMS) was first recognized in 1989 in New Mexico in 3 patients who had an illness with a unique array of symptoms, including peripheral blood eosinophilia and severe myalgias. (medscape.com)
  • Also see the Medscape Drugs & Diseases article Eosinophilia-Myalgia Syndrome . (medscape.com)
  • Eosinophilia-myalgia syndrome (EMS) is an illness characterized by pruritus, cutaneous lesions, edema, sclerodermoid changes, and joint pain, in addition to dramatic myalgia and eosinophilia. (medscape.com)
  • Filarial infection can also cause tropical pulmonary eosinophilia syndrome. (cdc.gov)
  • Clinical manifestations of tropical pulmonary eosinophilia syndrome include cough, shortness of breath, and wheezing. (cdc.gov)
  • Systemic eosinophilia, sometimes presenting with clinical features of vasculitis consistent with Churg-Strauss syndrome, has been reported. (nih.gov)
  • Rhonchi may be present in patients with Pulmonary tropical eosinophilia syndrome. (wikidoc.org)
  • Lupus-like syndrome associated with pulmonary reaction to nitrofurantoin has been reported. (druglib.com)
  • Little information is available regarding the prevalence and incidence of eosinophilic reactions to drugs or as a secondary histologic manifestation of pulmonary infection, parasitic infection (eg, Löffler syndrome, simple eosinophilic pneumonia), or neoplasia or as a component of Churg-Strauss syndrome. (medscape.com)
  • Tropical pulmonary eosinophilia syndrome is thought to represent a hypersensitivity reaction to microfilaria elaborated by Wuchereria bancrofti and Brugia malayi . (medscape.com)
  • Martínez-Cabot A, Messeguer A. Generation of quinoneimine intermediates in the bioactivation of 3-(N-phenylamino)alanine (PAA) by human liver microsomes: a potential link between eosinophilia-myalgia syndrome and toxic oil syndrome. (medscape.com)
  • Post-epidemic eosinophilia-myalgia syndrome associated with L-tryptophan. (medscape.com)
  • A heretofore undisclosed crux of eosinophilia-myalgia syndrome: compromised histamine degradation. (medscape.com)
  • Eosinophilia-Myalgia Syndrome: further correlations between compromised histamine degradation, eosinophilias and myopathies. (medscape.com)
  • AHR activation by tryptophan--pathogenic hallmark of Th17-mediated inflammation in eosinophilic fasciitis, eosinophilia-myalgia-syndrome and toxic oil syndrome? (medscape.com)
  • Swygert LA, Back EE, Auerbach SB, Sewell LE, Falk H. Eosinophilia-myalgia syndrome: mortality data from the US national surveillance system. (medscape.com)
  • Pulmonary manifestations of the eosinophilia-myalgia syndrome associated with tryptophan ingestion. (medscape.com)
  • Pulmonary disease associated with L-tryptophan-induced eosinophilic myalgia syndrome. (medscape.com)
  • De Schryver-Kecskemeti K, Bennert KW, Cooper GS, Yang P. Gastrointestinal involvement in L-tryptophan (L-Trp) associated eosinophilia-myalgia syndrome (EMS). (medscape.com)
  • Hepburn A, Coady A, Livingstone J, Pandit N. Eosinophilic cholecystitis as a possible late manifestation of the eosinophilia-myalgia syndrome. (medscape.com)
  • Tryptophan metabolism via the kynurenine pathway in patients with the eosinophilia-myalgia syndrome. (medscape.com)
  • L-tryptophan-induced eosinophilia-myalgia syndrome. (medscape.com)
  • Risk factors for developing eosinophilia myalgia syndrome among L-tryptophan users in New York. (medscape.com)
  • Eosinophilia-myalgia syndrome in patients ingesting a single source of L-tryptophan. (medscape.com)
  • a syndrome of fleeting pulmonary findings and peripheral blood eosinophilia, is another eosinophilic pulmonary disease. (merckmanuals.com)
  • Pulmonary opacities on chest imaging associated with blood eosinophilia are sometimes called PIE (pulmonary infiltrates with eosinophilia) syndrome. (merckmanuals.com)
  • Given the patient's history of recurrent sinusitis, asthma, eosinophilia, and coronary aneurysms, we diagnosed eosinophilic granulomatosis with polyangiitis ( Churg-Strauss syndrome , CSS) and cardiac involvement, and recommended high-dose corticosteroid treatment. (medscape.com)
  • Asthma may manifest with marked eosinophilia, with or without infiltrates. (medscape.com)
  • Asthma and chronic obstructive pulmonary disease (COPD) are two prevalent chronic airway diseases that have a high personal and social impact. (ersjournals.com)
  • Tofacitinib, as a JAK3 inhibitor, represents a potential therapy for treatment of allergic conditions associated with airway eosinophilia including asthma and rhinitis. (lclabs.com)
  • Simple pulmonary eosinophilia is inflammation of the lungs from an increase in eosinophils, a type of white blood cell. (medlineplus.gov)
  • A rare complication of simple pulmonary eosinophilia is a severe type of pneumonia called acute idiopathic eosinophilic pneumonia. (medlineplus.gov)
  • What is the required treatment for an individual with simple pulmonary eosinophilia? (consultant360.com)
  • Eosinophilia is a higher than normal level of disease-fighting white blood cells, called eosinophils. (cdc.gov)
  • In pathology, eosinophilic pneumonia refers to a histologic pattern of diffuse pulmonary infiltrates that contain prominent numbers of eosinophils . (medscape.com)
  • Eosinophilic pulmonary diseases are a heterogeneous group of disorders characterized by the accumulation of eosinophils in alveolar spaces, the interstitium, or both. (merckmanuals.com)
  • The condition of marked eosinophilia with pulmonary involvement was first termed tropical pulmonary eosinophilia in 1950. (wikipedia.org)
  • Lung biopsy is not part of the routine diagnostic workup of tropical pulmonary eosinophilia. (wikipedia.org)
  • No universal treatment guidelines have been established for tropical pulmonary eosinophilia. (wikipedia.org)
  • In some syndromes, such as tropical pulmonary eosinophilia (TPE) and chronic eosinophilic pneumonia (CEP), interstitial fibrosis may result from chronic inflammation. (medscape.com)
  • Distinguishing the histologic pattern of eosinophilic pneumonia from clinical syndromes that also contain the term eosinophilic pneumonia (eg, chronic eosinophilic pneumonia, tropical pulmonary eosinophilia, simple eosinophilic pneumonia, acute eosinophilic pneumonia) is important. (medscape.com)
  • His autopsy revealed severe pulmonary hemorrhage with alveolar vasculitis and cholesterol crystals in the brain, kidneys, liver, and the other organs. (neurology-jp.org)
  • It was possible that cholesterol embolization to multiple organs including the brain induced systemic vasculitis that caused pulmonary hemorrhage and his critical prognosis. (neurology-jp.org)
  • Eosinophilic Granulomatosis with Polyangiitis (EGPA) Eosinophilic granulomatosis with polyangiitis is a systemic small- and medium-vessel necrotizing vasculitis, characterized by extravascular granulomas, eosinophilia, and tissue infiltration. (merckmanuals.com)
  • Eosinophilia and pulmonary infiltrates have been reported in patients with AIDS, lymphoma, a variety of inflammatory lung diseases, and collagen vascular diseases (see Etiology ). (medscape.com)
  • Symptoms, blood eosinophilia and initial thorax CT findings improved after two months of methylprednisolone treatment. (scirp.org)
  • however, upon their withdrawal, the symptoms and esophageal eosinophilia recurred. (curehunter.com)
  • After discontinuation of montelukast therapy and administration of systemic corticosteroids the patient's symptoms reversed rapidly and there was prompt resolution of the pulmonary infiltrates. (lookformedical.com)
  • Result(s): After the noted interventions, there was a marked improvement of clinical symptoms, chest radiograph findings, and eosinophilia. (elsevierpure.com)
  • The airway inflammation of chronic obstructive pulmonary disease (COPD) is largely neutrophilic, but 20-40% of induced sputum samples from individuals with stable COPD have eosinophilic airway inflammation, associated with elevated levels of sputum interleukin (IL)-5. (medscape.com)
  • Dr. Macbruce has experience treating conditions like Respiratory Failure, Pleural Effusion and COPD (Chronic Obstructive Pulmonary Disease) among other conditions at varying frequencies. (sharecare.com)
  • The most common pulmonary complication is pulmonary hypertension from chronic embolization of ova. (medscape.com)
  • Other less common chronic manifestations involve the pulmonary, cardiac, and gastrointestinal systems. (medscape.com)
  • Chronic eosinophilic pneumonia is a rare disease characterized by systemic and pulmonary manifestations. (scirp.org)
  • Gaensler, E.A. and Carrington, C.B. (1977) Peripheral opacities in chronic eosinophilic pneumonia: The photographic negative of pulmonary edema. (scirp.org)
  • Chronic Pulmonary Heart Diseases (incl. (sharecare.com)
  • Agent Orange Exposure and Risk of Idiopathic Pulmonary Fibrosis Among U.S. Veterans. (ucsf.edu)
  • From "traction bronchiectasis" to honeycombing in idiopathic pulmonary fibrosis: a spectrum of bronchiolar remodeling also in radiology? (google.it)
  • Features and outcome of familial idiopathic pulmonary fibrosis. (google.it)
  • Aberrant expansion of KRT5+ basal cells in the distal lung accompanies progressive alveolar epithelial cell loss and tissue remodelling during fibrogenesis in idiopathic pulmonary fibrosis (IPF). (bvsalud.org)
  • A computed tomography (CT) scan revealed multifocal pulmonary opacities with surrounding ground-glass changes, as well as hepatic and splenic lesions. (cdc.gov)
  • Pulmonary diseases associated with tissue and/or blood eosinophilia are a heterogeneous group of disorders. (medscape.com)
  • 2.5 the centre of this region experiencing DDS events that eosinophilia ( 8 ) and tissue injury ( 9 ). (who.int)
  • A heterogeneous group of disorders with the common feature of prolonged eosinophilia of unknown cause and associated organ system dysfunction, including the heart, central nervous system, kidneys, lungs, gastrointestinal tract, and skin. (lookformedical.com)
  • In approximately a third of patients, the presentation may mimic pulmonary infection 6 . (radiopaedia.org)
  • High-resolution CT of nontuberculous mycobacteria pulmonary infection in immunocompetent, non-HIV-positive patients. (google.it)
  • My projects investigate the mechanisms that cause enhanced disease and pulmonary eosinophilia upon RSV infection of vaccinated hosts. (uiowa.edu)
  • Differential role of gamma interferon in inhibiting pulmonary eosinophilia and exacerbating systemic disease in fusion protein-immunized mice undergoing challenge infection with respiratory syncytial virus. (uiowa.edu)
  • Cholesterol embolization should be considered when we see a patient with brain lesions accompanied with eosinophilia. (neurology-jp.org)
  • panels A, B). The pulmonary and hepatic lesions were 18F-fluorodeoxyglucose–avid on positive emission tomography scan. (cdc.gov)
  • Intrinsic pulmonary eosinophilic syndromes are generally idiopathic in nature. (medscape.com)
  • Pulmonary eosinophilic syndromes are rare, and the exact incidence and prevalence are unknown. (medscape.com)
  • SPDEF was required for goblet cell differentiation and pulmonary Th2 inflammation in response to house dust mite (HDM) extract, as both were decreased in neonatal and adult Spdef(-/-) mice compared with control animals. (nih.gov)
  • In clinical trials of nitrofurantoin monohydrate/macrocrystals, the most frequent laboratory adverse events (1 to 5%), without regard to drug relationship, were as follows: eosinophilia, increased AST (SGOT), increased ALT (SGPT), decreased hemoglobin, increased serum phosphorus. (druglib.com)
  • Occupational Exposures in Nontuberculous Mycobacterial Pulmonary Disease. (ucsf.edu)
  • Alcian Blue and Pyronine Y histochemical stains permit assessment of multiple parameters in pulmonary disease models. (uiowa.edu)
  • Eosinophilia and lung involvement differentiate this disease from POLYARTERITIS NODOSA. (lookformedical.com)
  • Patients with drug-induced pulmonary eosinophilia commonly have crackles on physical examination. (medscape.com)
  • Saint-Pierre MD, Moran-Mendoza O. Acetaminophen Use: An Unusual Cause of Drug-Induced Pulmonary Eosinophilia. (medscape.com)
  • Prediction of drug-induced eosinophilia adverse effect by using SVM and naïve Bayesian approaches. (medscape.com)
  • Rare case of occupational pulmonary hemorrhage in a firefighter. (ucsf.edu)
  • pulmonary histiocytosis X or Langerhans cell granulomatosis). (medscape.com)
  • JAK3 plays an important role in pulmonary eosinophilia in the allergic mouse model. (lclabs.com)
  • Migrating parasites traversing the lungs may cause bronchospasm, dyspnea, and pulmonary infiltrates. (medscape.com)
  • The reported prevalence of pulmonary toxicity in patients receiving amiodarone is ~10% (range 2-18%) 8 . (radiopaedia.org)
  • This and other factors-for example, eosinophil-apoptosis impairment through high levels of soluble CD95-might account for the persistent eosinophilia in active CSS. (medscape.com)