HypertensionWedge pressureVeno-occlusiArterial pressureHemangiomatosisArteriesLungVenousLeak SyndromeIncreased pulmonary pressureEdemaMean pulmonaryLungsSystemicCardiacAlveolar capillarySyndromePathogenesisCongenitalPatientsAcuteOxygenEmbolismParenchymaPressureDivision of PulmonaryCirculationARDSDisordersVasculatureAbnormalCritical Care MedVesselAbnormalitiesAlveoliOedemaVasodilatorsDiseaseClinical
Hypertension46
- It is a rare cause of pulmonary hypertension, and occurs predominantly in young adults. (wikipedia.org)
- Together with pulmonary veno-occlusive disease, PCH comprises WHO Group I' causes for pulmonary hypertension. (wikipedia.org)
- Respir Med 131:215-219 Akagi S, Nakamura K, Matsubara H, Ogawa A, Sarashina T, Ejiri K, Ito H (2015) Epoprostenol therapy for pulmonary arterial hypertension. (wikipedia.org)
- These changes restrict normal blood flow, which causes high blood pressure in the pulmonary arteries (pulmonary hypertension) and requires the heart to pump harder. (medlineplus.gov)
- Pre-Capillary, Combined, and Post-Capillary Pulmonary Hypertension: A Pathophysiological Continuum. (acc.org)
- While therapy for patients with pulmonary arterial hypertension (PAH) has evolved into an integrated, and mostly evidence-based, treatment approach combining supportive, pharmacologic and surgical therapies, the optimal treatment of patients with left heart disease with preserved left ventricular systolic function and severe pulmonary hypertension (PH-HFpEF) remains unclear. (acc.org)
- Hemodynamic key parameters such as mean pulmonary artery pressure (46 ± 9 mm Hg) and cardiac index (2.2 ± 0.7 l/min/m 2 ) were as severely compromised as in patients with idiopathic pulmonary arterial hypertension (IPAH), and the elevated transpulmonary gradient (26 ± 9 mm Hg) documents a relevant pre-capillary component in the presence of severe combined post- and pre-capillary PH (Cpc-PH). (acc.org)
- Inspired by the AMBITION (Ambrisentan and Tadalafil in Patients with Pulmonary Arterial Hypertension) investigators 4 we explored the question whether in COMPERA all patients fulfilling the formal diagnostic criteria of IPAH are alike (e.g. typical IPAH), or is there a group of patients with "atypical" IPAH? (acc.org)
- Despite currently available treatments, the prognoses of pulmonary arterial hypertension (PAH) and pulmonary capillary hemangiomatosis (PCH) remain poor. (nih.gov)
- Platelet-derived growth factor and its receptor (PDGFR) have been implicated in the pathogenesis of pulmonary hypertension in PAH and PCH. (nih.gov)
- Left heart diseases (LHDs) are the most frequent cause of pulmonary hypertension (PH). (romanianjournalcardiology.ro)
- Persistent pulmonary hypertension of the newborn (PPHN) is defined as the failure of the normal circulatory transition that occurs after birth. (medscape.com)
- It is a syndrome characterized by marked pulmonary hypertension that causes hypoxemia secondary to right-to-left shunting of blood at the foramen ovale and ductus arteriosus. (medscape.com)
- Idiopathic persistent pulmonary hypertension of the newborn can present without signs of acute perinatal distress. (medscape.com)
- In contrast to adult primary pulmonary hypertension, the newborn syndrome is not defined by a specific pressure of the pulmonary circulation. (medscape.com)
- Pulmonary hypertension is high blood pressure in your pulmonary arteries, which carry oxygen-poor blood from your heart to your lungs. (clevelandclinic.org)
- Pulmonary hypertension causes your pulmonary arteries to become narrow. (clevelandclinic.org)
- What is pulmonary hypertension? (clevelandclinic.org)
- Pulmonary hypertension (PH) is a general diagnosis that means you have high blood pressure in your pulmonary arteries . (clevelandclinic.org)
- Pulmonary hypertension has many different causes. (clevelandclinic.org)
- Pulmonary hypertension is dangerous because it disrupts the flow of blood through your heart and lungs . (clevelandclinic.org)
- How does pulmonary hypertension affect my body? (clevelandclinic.org)
- Without treatment, pulmonary hypertension can overtax your heart and eventually be fatal. (clevelandclinic.org)
- Because pulmonary hypertension can affect your entire body, it's essential that you're diagnosed and treated as early as possible. (clevelandclinic.org)
- What are the different types of pulmonary hypertension? (clevelandclinic.org)
- The World Health Organization (WHO) divides pulmonary hypertension into five groups based on its cause. (clevelandclinic.org)
- Who does pulmonary hypertension affect? (clevelandclinic.org)
- Pulmonary hypertension can affect adults at any age. (clevelandclinic.org)
- How common is pulmonary hypertension? (clevelandclinic.org)
- Some types of PH are rare, such as pulmonary arterial hypertension (PAH) and PH caused by blood clots. (clevelandclinic.org)
- Since the 1st World Symposium on Pulmonary Hypertension (WSPH) in 1973, pulmonary hypertension (PH) has been arbitrarily defined as mean pulmonary arterial pressure (mPAP) ≥25 mmHg at rest, measured by right heart catheterisation. (ersjournals.com)
- Regarding clinical classification, the main Task Force changes were the inclusion in group 1 of a subgroup "pulmonary arterial hypertension (PAH) long-term responders to calcium channel blockers", due to the specific prognostic and management of these patients, and a subgroup "PAH with overt features of venous/capillaries (pulmonary veno-occlusive disease/pulmonary capillary haemangiomatosis) involvement", due to evidence suggesting a continuum between arterial, capillary and vein involvement in PAH. (ersjournals.com)
- The main objectives of our Task Force were to reassess haemodynamic definitions and the clinical classification of pulmonary hypertension (PH). (ersjournals.com)
- Since the 1st World Symposium on Pulmonary Hypertension (WSPH) organised by the WHO in Geneva in 1973, PH has been defined as mPAP ≥25 mmHg measured by right heart catheterisation (RHC) in the supine position at rest [ 2 ]. (ersjournals.com)
- The term idiopathic pulmonary arterial hypertension (IPAH) is used to categorize patients with capillary pulmonary hypertension of unknown origin. (uni-koeln.de)
- Pulmonary hypertension is often the common link between lung dysfunction and the heart in cor pulmonale. (medscape.com)
- The pathophysiology of cor pulmonale is a result of increased right-sided filling pressures from pulmonary hypertension that is associated with diseases of the lung. (medscape.com)
- Several different pathophysiologic mechanisms can lead to pulmonary hypertension and, subsequently, to cor pulmonale. (medscape.com)
- The World Health Organization (WHO) has five classifications for pulmonary hypertension, and all except one of these groups can result in cor pulmonale (WHO Classification group 2 is pulmonary artery hypertension due to left ventricular [LV] dysfunction). (medscape.com)
- Group 5: Pulmonary hypertension caused by other diseases or conditions, including sarcoidosis, polycythemia vera (which can lead to increased blood viscosity and, subsequently, pulmonary hypertension), vasculitis, and other disorders. (medscape.com)
- The surgical repair of congenital heart defects in children with preoperative pulmonary hypertension (PH) is to varying degree associated with the occurrence of postoperative PH. (lu.se)
- All three children with bad outcome had combined cardiac lesions causing post-capillary pulmonary hypertension. (lu.se)
- Pulmonary hypertension is increased pressure in the pulmonary circulation. (msdmanuals.com)
- Severe pulmonary hypertension leads to right ventricular overload and failure. (msdmanuals.com)
- Many conditions and drugs cause pulmonary hypertension. (msdmanuals.com)
- In the first group (pulmonary arterial hypertension [PAH]), the primary disorder affects the small pulmonary arterioles. (msdmanuals.com)
Wedge pressure6
- 5 An example might be the acquisition and interpretation of the pulmonary artery wedge pressure and its role for separating pre- from post-capillary PH. (acc.org)
- However, this abnormal elevation of mPAP is not sufficient to define pulmonary vascular disease as it can be due to an increase in cardiac output or pulmonary arterial wedge pressure. (ersjournals.com)
- In this population, the use of NATRECOR reduced pulmonary capillary wedge pressure and improved symptomatic dyspnea when measured at 3 hours of infusion. (nih.gov)
- In this population, the use of NATRECOR reduced pulmonary capillary wedge pressure and improved short term (3 hours) symptoms of dyspnea. (nih.gov)
- Background :The aim of this study was to validate whether pulmonary capillary wedge pressure estimated using transoesophageal echocardiography in anaesthetised patients receiving mechanical ventilation can be comparable to gold standard method of estimating PCWP by using pulmonary artery catheter. (amrita.edu)
- a restrictive filling pattern is highly specific for elevated pulmonary wedge pressure in this setting. (bmj.com)
Veno-occlusi8
- Indeed, there is some evidence to suggest that PCH and pulmonary veno-occlusive disease are different forms of a similar disease process. (wikipedia.org)
- Pulmonary veno-occlusive disease This condition has been reported in patients with Ehlers Danlos syndrome, CREST syndrome and scimitar syndrome. (wikipedia.org)
- Chaisson NF, Dodson MW, Elliott CG (2016) Pulmonary Capillary Hemangiomatosis and Pulmonary Veno-occlusive Disease. (wikipedia.org)
- Appl Clin Genet 8:181-8 Ogawa A, Miyaji K, Matsubara H (2017) Efficacy and safety of long-term imatinib therapy for patients with pulmonary veno-occlusive disease and pulmonary capillary hemangiomatosis. (wikipedia.org)
- Acta Med Okayama 69(3):129-136 Szturmowicz M, Kacprzak A, Szołkowska M, Burakowska B, Szczepulska E, Kuś J (2018) Pulmonary veno-occlusive disease: pathogenesis, risk factors, clinical features and diagnostic algorithm - state of the art. (wikipedia.org)
- Clinical and Hemodynamic Responses to Imatinib in Pulmonary Veno-Occlusive Disease/Pulmonary. (sagepub.com)
- Beneficial Effects of Imatinib in a Patient with Suspected Pulmonary Veno-Occlusive Disease. (sagepub.com)
- Use of vasodilators for the treatment of pulmonary veno-occlusive disease and pulmonary capillary hemangiomatosis: A systematic review. (sagepub.com)
Arterial pressure9
- When measured by echocardiography or pulmonary angiography, the pulmonary arterial pressure is typically elevated. (wikipedia.org)
- Another term used to define this clinical entity is "mixed PH" as to emphasize both pre-cappilary and post-capillary contributions to the elevated pulmonary arterial pressure (PAP)8. (romanianjournalcardiology.ro)
- The diagnosis is confirmed regardless of the pulmonary arterial pressure, as long as it is accompanied by a right-to-left shunt and absence of congenital heart disease. (medscape.com)
- In 1961, a report of the World Health Organization (WHO) Expert Committee on Chronic Cor Pulmonale mentioned clearly that the mean pulmonary arterial pressure (mPAP) does not normally exceed 15 mmHg when the subject is at rest in a lying position, and that the value was little affected by age and never exceeded 20 mmHg [ 1 ]. (ersjournals.com)
- The end result of the above mechanisms is increased pulmonary arterial pressure and resistance. (medscape.com)
- At a critical point, a further increase in pulmonary arterial pressure and resistance produces significant RV dilatation, an increase in RV end-diastolic pressure, and RV circulatory failure. (medscape.com)
- The objective of this study was to follow up children with severe postoperative PH (pulmonary arterial/aortic pressure ratio ≥ 1.0) to evaluate if pulmonary arterial pressure spontaneously normalized or needed PH-targeting therapy and to identify potential high-risk diagnoses for bad outcome. (lu.se)
- The remaining 17 children normalized their pulmonary arterial pressure without the use of PH-targeting drugs at any time during the follow-up. (lu.se)
- Normalization of the pulmonary arterial pressure occurred in almost all children with severe postoperative PH, without any need of supplemental PH-targeting therapies. (lu.se)
Hemangiomatosis5
- Pulmonary capillary hemangiomatosis (PCH) is a disease affecting the blood vessels of the lungs, where abnormal capillary proliferation and venous fibrous intimal thickening result in progressive increase in vascular resistance. (wikipedia.org)
- Chest 151(4):821-828 Park MA, Shin SY, Kim YJ, Park MJ, Lee SH (2017) Vascular Ehlers-Danlos syndrome with cryptorchidism, recurrent pneumothorax, and pulmonary capillary hemangiomatosis-like foci: A case report.Medicine (Baltimore) 96(47):e8853 Diao XL, Mu XD, Jin ML (2017) Pulmonary capillary hemangiomatosis associated with CREST syndrome: A challenge of diagnosis and treatment. (wikipedia.org)
- Chin Med J (Engl) 130(21):2645-2646 Güttinger E, Vrugt B, Speich R, Ulrich S, Schwitz F, Arrigo M, Huber LC (2016) Reactive pulmonary capillary hemangiomatosis and pulmonary veno-acclusive disease in a patient with repaired scimitar syndrome. (wikipedia.org)
- Case Rep Cardiol 2016:9384126 Ma L, Bao R (2015) Pulmonary capillary hemangiomatosis: a focus on the EIF2AK4 mutation in onset and pathogenesis. (wikipedia.org)
- Adv Respir Med 86(3) Sposito Cavallo SL, Macias Sobrino LA, Marenco Altamar LJ, Mejía Alquichire AF (2017) Congenital pulmonary capillary hemangiomatosis in a newborn. (wikipedia.org)
Arteries14
- The veins that carry blood from the lungs into the heart (pulmonary veins) are improperly positioned and may be abnormally bundled together with arteries that carry blood from the heart to the lungs (pulmonary arteries). (medlineplus.gov)
- The muscle tissue in the walls of the pulmonary arteries may be overgrown, resulting in thicker artery walls and a narrower channel. (medlineplus.gov)
- High blood pressure in your pulmonary arteries causes these arteries to become narrow. (clevelandclinic.org)
- Blood clots in your pulmonary arteries. (clevelandclinic.org)
- High blood pressure in your pulmonary arteries forces your heart to work harder to send oxygen-poor blood to your lungs. (clevelandclinic.org)
- PAH makes your pulmonary arteries become narrow, thick or stiff. (clevelandclinic.org)
- Less blood can flow through, which raises the pressure in your pulmonary arteries. (clevelandclinic.org)
- Blood backs up in your heart, raising the pressure in your pulmonary arteries. (clevelandclinic.org)
- Less blood can flow through your lungs, raising the pressure in your pulmonary arteries. (clevelandclinic.org)
- The small veins and arteries that branch into capillaries. (studystack.com)
- its arteries are branches of the bronchial arteries, and its veins mingle with the pulmonary network of capillaries . (britannica.com)
- Do frogs have pulmonary arteries? (onteenstoday.com)
- Pulmonary Embolism (PE) Pulmonary embolism (PE) is the occlusion of pulmonary arteries by thrombi that originate elsewhere, typically in the large veins of the legs or pelvis. (msdmanuals.com)
- The cardiovascular system consists of the heart, which is an anatomical pump, with its intricate conduits (arteries, veins, and capillaries) that traverse the whole human body carrying blood. (medscape.com)
Lung10
- In these studies, the method demonstrated that the acute anesthetized lung lymph fistula sheep model was associated with a significant pulmonary capillary protein leak. (dtic.mil)
- The patients were aged 67 ± 13 years, their diffusion capacity of the lung for carbon monoxide was 29 ± 8%, and their mean pulmonary artery pressure was 40 ± 7 mmHg. (sagepub.com)
- During the years, substantial focus has been placed on the role of the lung, ventilation and pulmonary gas exchange limitations on exercise impairment at altitude. (bmj.com)
- These data confirm the established role of oxidant/antioxidant imbalance in the pathogenesis of idiopathic pulmonary fibrosis, and show the potential of induced sputum to directly study inflammatory processes and surrogate markers in interstitial lung diseases like idiopathic pulmonary fibrosis. (ersjournals.com)
- Idiopathic pulmonary fibrosis (IPF) or cryptogenic fibrosing alveolitis is a chronic inflammatory disease of the lower respiratory tract leading to diffuse scarring of the lung parenchyma and end-stage tissue fibrosis 1 , 2 . (ersjournals.com)
- Pulmonary-function tests in IPF patients revealed a mean total lung capacity of 60±4% of predicted, and a diffusing capacity of 57±6% pred. (ersjournals.com)
- Conclusions Abnormalities in pulmonary vascular volumes may explain some of the lung function abnormalities and the decline in lung function seen in adults with SCD. (bmj.com)
- Alterations in pulmonary vascular volumes due to anaemia in SCD patients may be responsible for some of their lung function abnormalities and changes seen on HRCT and their decline in lung function. (bmj.com)
- Beneath its inner side is a network of tiny lymph channels, or capillaries, that penetrate the lung substance, or parenchyma , and drain to the lymph nodes at the hilus of each lung, the point of entrance and departure for bronchi , blood vessels, and nerves. (britannica.com)
- Once gas exchange occurs in the lung tissue, the oxygen-laden blood is carried to the left atrium via the pulmonary veins, hence completing the pulmonary circuit (see the image above). (medscape.com)
Venous2
- According to the International Society for the Study of Vascular Anomalies (ISSVA) classification, vascular malformations are classified according to their predominant vessel type, such as arterial, venous, lymphatic, capillary, or complex (a combination of different vessels). (medscape.com)
- LHDs determine an increase in left ventricular filling pressures and pulmonary venous pressures (1). (romanianjournalcardiology.ro)
Leak Syndrome2
- SCLS, systemic capillary leak syndrome. (cdc.gov)
- Meanwhile, there was a severe pulmonary edema and capillary leak syndrome. (sermo.com)
Increased pulmonary pressure1
- An important group of patients with LHDs have a disposition to develop a pre-capillary component to the increased pulmonary pressure, resulting in a mixed picture of pre-capillary and post-capillary PH (7). (romanianjournalcardiology.ro)
Edema2
- The patient was placed in a nearby clinic under intubation and ventilation with a core body temperature of 32 ° C. In a whole-body tomography, there were pronounced pulmonary edema, aspirated foreign bodies in both lungs, and a fluid-filled gastrointestinal tract. (sermo.com)
- The most intense exposures damage the alveolar capillary parenchyma resulting in pulmonary edema. (cdc.gov)
Mean pulmonary2
- These patients present with a reactive or "out of proportion" PH defined as elevated pulmonary vascular resistance (PVR ≥3 Wood units) and increased transpulmonary gradient (TPG ≥12 mmHg), where the TPG is the difference between mean pulmonary pressure and left atrial pressure. (romanianjournalcardiology.ro)
- In addition, imatinib improved the arterial oxygen partial pressure in this and another patient (these two also experienced a decreased mean pulmonary artery pressure and pulmonary vascular resistance after imatinib usage).ConclusionsThis study indicated that imatinib improves the clinical condition, including pulmonary hemodynamics, of some patients with PVOD/PCH. (sagepub.com)
Lungs4
- Arch Argent Pediatr 115(1):e17-e20 Wagenvoort CA, Beetstra A, Spijker J (1978) Capillary haemangiomatosis of the lungs. (wikipedia.org)
- Alveolar capillary dysplasia with misalignment of pulmonary veins (ACD/MPV) is a disorder affecting the development of the lungs and their blood vessels. (medlineplus.gov)
- The pulmonary circuit moves blood to the lungs to pick up oxygen. (onteenstoday.com)
- This blood is pumped down to the right ventricle via the tricuspid valve and eventually through the pulmonic valve, leading to the pulmonary trunk that takes the oxygen deprived blood to the lungs for gas exchange. (medscape.com)
Systemic3
- They are the carotid (the third), systemic (the fourth), and pulmonary (the sixth) arches. (onteenstoday.com)
- the left side chambers supply the systemic circulation, and the right side chambers supply the pulmonary circulation. (medscape.com)
- Systemic and pulmonary circulation. (medscape.com)
Cardiac1
- Methods : A cross sectional validity study conducted in a tertiary care cardiac centre in south India over a period of 6 months from February 2016 - August 2016 among 100 patients undergoing cardiac surgery where intraoperative TEE and pulmonary artery catheter used. (amrita.edu)
Alveolar capillary1
- Dm: diffusing capacity of the alveolar capillary membrane. (biomedcentral.com)
Syndrome3
- pulmonary embolism (more common) and acute respiratory distress syndrome ( ARDS ). (medscape.com)
- Acute chest syndrome is the commonest cause of death in young adults, and pulmonary dysfunction is a major contributor to morbidity in aging adults with SCD. (bmj.com)
- The clinical syndrome is characterized by hemoptysis, falling hematocrit, hypoxemic respiratory failure and diffuse pulmonary infiltrates. (medscape.com)
Pathogenesis1
- [ 5 ] This may suggest that VEGF and VEGF-R could contribute to the pathogenesis of capillary malformations by inducing vessel proliferation and/or vasodilatation. (medscape.com)
Congenital1
- Happle contends that the term capillary malformation should be used as a more generalized designation for several congenital disorders of dilated capillaries (eg, angiokeratomas , nevus anemicus , cutis marmorata telangiectatica congenita ). (medscape.com)
Patients5
- The dose of pulmonary vasodilators remained unchanged during the assessment of imatinib.ResultsThe medical records of five patients with PVOD/PCH were reviewed. (sagepub.com)
- Therefore, evaluation of GSH levels of the lower respiratory tract of IPF patients by means of induced sputum, a safe and reproducible tool that has been extensively studied in asthma or chronic obstructive pulmonary disease, has been assessed here. (ersjournals.com)
- Treating Patients with Pulmonary Embolism: Which Patients Can Be Treated as Outpatients? (medscape.org)
- In intensive care, sitting patients up reduces the risk of pulmonary aspiration and ventilator associated pneumonia. (bionity.com)
- Dr. Harkins has served as Division Chief Pulmonary Critical Care in Sleep Medicine for the last 3 years in the Department of Internal Medicine at the University of New Mexico and has been on faculty since 1999 and she has taken care of numerous hantavirus patients in the University of New Mexico ICU. (cdc.gov)
Acute1
- Acute alcohol poisoning is a relatively common cause of severe pulmonary aspiration as the alcohol renders the victim unconscious and can induce vomiting . (bionity.com)
Oxygen5
- It is through these alveolar capillaries that inhaled oxygen enters the bloodstream for distribution throughout the body and carbon dioxide leaves the bloodstream to be exhaled. (medlineplus.gov)
- These abnormalities in capillary number and location impede the exchange of oxygen and carbon dioxide. (medlineplus.gov)
- Oxygen crosses into the pulmonary capillaries from the alveoli to be transported by the bloodstream. (healthbenefitstimes.com)
- The work of Paul Bert, who demonstrated the toxic effects of oxygen (producing generalized seizures), as well as the work of J. Lorrain-Smith, who demonstrated pulmonary oxygen toxicity, were used with Navy divers. (medscape.com)
- The main problems arise from the tendency of the red blood cells to become sickle-shaped and block capillaries at low oxygen tension. (who.int)
Embolism3
- The underlying pathophysiology in a massive pulmonary embolism causing cor pulmonale is the sudden increase in pulmonary resistance. (medscape.com)
- A diagnosis of pulmonary embolism (PE) is confirmed. (medscape.org)
- Risk factors for pulmonary embolism are. (msdmanuals.com)
Parenchyma1
- It refers to bleeding that originates in the pulmonary microvasculature instead of the parenchyma or bronchial circulation. (medscape.com)
Pressure9
- This can be difficult if the pulmonary pressure is high. (wikipedia.org)
- Overall, the PH-HFpEF cohort described in our paper is the result of a restrictive selection process at PH expert centers, and probably does not reflect the usual heart failure patient with some degree of pulmonary artery pressure elevation. (acc.org)
- Pulmonary capillary pressure (Pcp) is the primary driving force determining the fluid flux across pulmonary capillary wall. (e-journal.gr)
- LPS has been administered (150μg/Kg BW) in the right atrium of 8 anesthetized and mechanical ventilated pigs (Group A) and the Pcp was calculated from pulmonary artery pressure tracings using the Gaar equation before, after LPS infusion and in 20min intervals for two hours. (e-journal.gr)
- Pulmonary Artery Occlusion Pressure showed no changes in both groups. (e-journal.gr)
- Our study showed that endotoxin intravenous administration is significantly alterating the pulmonary capillary pressure in pigs under anesthesia and mechanical ventilation. (e-journal.gr)
- On the contrary the pulmonary artery occlusion pressure was not been affected by the endotoxin administration during our observation. (e-journal.gr)
- This puts more stress on the right side of your heart and raises pulmonary blood pressure. (clevelandclinic.org)
- Diagnosis is made by finding elevated pulmonary artery pressure (estimated by echocardiography and confirmed by right heart catheterization). (msdmanuals.com)
Division of Pulmonary1
- Robert Promisloff, DO, FACP, FCCP, is a clinical professor emeritus of medicine in the Division of Pulmonary & Critical Care Medicine at Drexel University College of Medicine. (drexel.edu)
Circulation1
- Diffuse alveolar hemorrhage (DAH) is a life-threatening condition which refers to hemorrhage originating in the pulmonary microvasculature, rather than from the bronchial circulation or parenchymal abnormalities. (medscape.com)
ARDS1
- Pulmonary gamma scintigraphy is a rapid, non-invasive technique for measuring a pulmonary capillary protein leak in ARDS. (dtic.mil)
Disorders3
- Oxidative stress of the lower respiratory tract has been repeatedly linked to IPF, and an increased oxidant burden contributes to tissue remodelling and fibroblast activation in IPF and related disorders, like drug-induced pulmonary fibrosis 6 - 8 . (ersjournals.com)
- these disorders include chronic obstructive pulmonary disease (COPD), which is the most common cause of for pulmonale. (medscape.com)
- Pulmonary renal syndromes, connective tissue disorders and drugs make up the majority of the cases of DAH. (medscape.com)
Vasculature3
- Reactive Group 2 PH is defi ned by an elevated TPG ≥12 mmHg and PVR ≥3 Wood units, indicating the presence of functional and/or structural abnormalities of the pulmonary arterial vasculature besides the elevated PCWP. (romanianjournalcardiology.ro)
- Histological changes of pulmonary vasculature bed appear to be the same as in precapillary forms of PH (10). (romanianjournalcardiology.ro)
- SARS-CoV-2 infection primarily affects the pulmonary system, but accumulating evidence suggests that it also affects the pan-vasculature in the extrapulmonary systems by directly (via virus infection) or indirectly (via cytokine storm), causing endothelial dysfunction (endotheliitis, endothelialitis and endotheliopathy) and multi-organ injury. (nature.com)
Abnormal2
- Mutations in the FOXF1 gene that cause ACD/MPV result in an inactive protein that cannot regulate development, leading to abnormal formation of the pulmonary blood vessels and gastrointestinal tract. (medlineplus.gov)
- Capillary malformations and other vascular malformations are the result of abnormal morphogenesis. (medscape.com)
Critical Care Med1
- Department of Pulmonary and Critical Care Medicine, The Third Hospital of Changsha, Changsha 410015, China. (bvsalud.org)
Vessel5
- Although some capillary malformations may be associated with other vessel malformations, most occur alone as venulocapillary malformations. (medscape.com)
- Capillary malformations are characterized by ectatic papillary dermal capillaries and postcapillary venules in the upper reticular dermis, with some evidence of increased vessel density and no apparent proliferation of vessels. (medscape.com)
- One study demonstrated a mean vessel depth of 0.46 mm in capillary malformations, suggesting that most of the vessels are superficial. (medscape.com)
- [ 3 ] Confocal microscopic studies demonstrate an inverse correlation between nerve density and blood vessel diameter and evidence that capillary malformations with the lowest nerve density exhibit the highest blood vessel density and the poorest response to laser intervention. (medscape.com)
- Capillaries are made up of only one kind of vessel tissue called? (studystack.com)
Abnormalities3
- There are no significant associated abnormalities in the pulmonary artery structure or function, therefore specific pulmonary artery vasodilatator therapy is not considered. (romanianjournalcardiology.ro)
- Reactive reversible Group 2 PH is defined by normalization of the TPG and PVR during vasodilator challenge, suggesting a predominance of functional over structural abnormalities of the pulmonary arteiral vessels. (romanianjournalcardiology.ro)
- Structural over functional abnormalities of the pulmonary arterial vascular bed are presumed to exist. (romanianjournalcardiology.ro)
Alveoli1
- The number of capillaries is drastically reduced, and existing capillaries are improperly positioned within the walls of the alveoli. (medlineplus.gov)
Oedema1
- This finding may be important, because under specific circumstances such Pcp increases may lead to fluid extravasation and pulmonary oedema. (e-journal.gr)
Vasodilators1
- Treatment is with pulmonary vasodilators and diuretics. (msdmanuals.com)
Disease4
- Suspect PPHN whenever the level of hypoxemia is out of proportion to the level of pulmonary disease. (medscape.com)
- He has a clinical interest in chronic obstructive pulmonary disease and end-of-life care. (drexel.edu)
- Idiopathic pulmonary fibrosis (IPF) is a disease of unknown aetiology. (ersjournals.com)
- Mesenchymal stromal cells: a novel therapy for the treatment of chronic obstructive pulmonary disease? (bmj.com)
Clinical1
- Overall, the multifunctional capillary sensor exhibits great potential in real- time blood gas analysis , and clinical application of multi-parameter biological detection . (bvsalud.org)