Virus was not detected in heart tissues of adolescent ts 1 survivors, but inoculation of these mice with CVB3(m) resulted in virus concentrations similar in titers to those found in CVB3(m)-inoculated normal adolescent mice. (nih.gov)
AB - The pneumotropism of Sendai virus in mice was studied in relation to the activation and replication of the virus in the lung. (nih.gov)
Inactive Sendai virus grown in LLC-MK(2) cells, which possessed an uncleaved precursor glycoprotein, F, and was noninfectious to tissue culture cells, neither grew nor caused pathological changes in the lung of mice. (nih.gov)
The overall results suggest that some activating mechanism for the progeny virus of wild-type Sendai virus exists in the lung of mice and the principle (activator) responsible for this phenomenon has a character similar to trypsin. (nih.gov)
And then we progressed, or moved, from there to studying indigenous viruses of mice, because we were beginning to use mice a lot for experimental purposes, and it became very clear that there were a lot of viruses already in the mice that weren't recognized, hadn't been classified, or tests worked out for their characterization. (nih.gov)
And when Sarah Stewart and Bernice Eddy isolated Polyoma virus, we got involved in seeing how it could be handled in the laboratory and began a whole series of experiments that had to do with studying the natural history of Polyoma virus infection in lab mice, and Bob Huebner's particular interest in mice in the wild. (nih.gov)
And Ludwig Gross's induction of leukemia in mice with AKR thymic lymphomas met the same sort of reaction. (nih.gov)
Mouse2
PMID- 6299951 TI - Pneumotropism of Sendai virus in relation to protease-mediated activation in mouse lungs. (nih.gov)
So, we got rather deeply into mouse viruses. (nih.gov)