• Protriptyline, sold under the brand name Vivactil among others, is a tricyclic antidepressant (TCA), specifically a secondary amine, indicated for the treatment of depression and attention-deficit hyperactivity disorder (ADHD). (wikipedia.org)
  • Another class of tricyclics, called secondary amine tricyclic antidepressants, include nortriptyline (Aventyl, Pamelor) and protriptyline (Vivactil). (brighthub.com)
  • The application (3) shows the enrichment of various polar pharmaceutical drugs (e.g. the antiretroviral drug AZT, the tricyclic antidepressants doxepin and protriptyline as well as the blood pressure regulator propranolol) on a CHROMABOND 3 mL HLB SPE cartridge filled with 200 mg of 60 µm N -vinylpyrrolidone - divinylbenzene copolymer resin (REF 730924 ). (mn-net.com)
  • Protriptyline has been found in some studies to have a more rapid onset of action than imipramine or amitriptyline. (nih.gov)
  • Protriptyline: The tricyclic antidepressant, protriptyline , increases the sympathomimetic effect of orciprenaline . (pediatriconcall.com)
  • Protriptyline hydrochloride tablets are indicated for the treatment of symptoms of mental depression in patients who are under close medical supervision. (nih.gov)
  • Protriptyline hydrochloride tablets are contraindicated in patients who have shown prior hypersensitivity to it. (nih.gov)
  • Protriptyline is available as 5 mg and 10 mg tablets. (wikipedia.org)
  • Protriptyline HCl is supplied as 5 mg or 10 mg film-coated tablets. (nih.gov)
  • Before starting treatment, people should discuss the relative risks and benefits of treatment with their doctors to help determine if protriptyline is the right antidepressant for them. (wikipedia.org)
  • Anyone considering the use of protriptyline hydrochloride or any other antidepressant in a child, adolescent, or young adult must balance this risk with the clinical need. (nih.gov)
  • Protriptyline hydrochloride is an antidepressant agent. (nih.gov)
  • Like all TCAs, protriptyline should be used cautiously and with close physician supervision. (wikipedia.org)
  • Protriptyline should then be initiated cautiously with gradual increase in dosage until optimum response is achieved. (nih.gov)
  • Uniquely among most of the TCAs, protriptyline tends to be energizing instead of sedating, and is sometimes used for narcolepsy to achieve a wakefulness-promoting effect. (wikipedia.org)
  • TCAs including protriptyline are also used to reduce the incidence of recurring headaches such as migraine, and for other types of chronic pain. (wikipedia.org)
  • Protriptyline shares side effects common to all TCAs. (wikipedia.org)
  • A common problem with TCAs is sedation (drowsiness, lack of physical and mental alertness), but protriptyline is considered the least sedating agent among this class of agents. (wikipedia.org)
  • In rare cases in which patients with cardiovascular disease must take protriptyline, they should be monitored closely for cardiac rhythm disturbances and signs of cardiac stress or damage. (wikipedia.org)
  • Protriptyline is contraindicated in patients taking cisapride because of the possibility of adverse cardiac interactions including prolongation of the QT interval, cardiac arrhythmias and conduction system disturbances. (nih.gov)
  • It is contraindicated to prescribe protriptyline in patient who is consuming cisaprideà QT prolongation, cardiac arrhythmias, and conduction system disturbances. (essentialsofmedicine.com)
  • Protriptyline is used primarily to treat depression and to treat the combination of symptoms of anxiety and depression. (wikipedia.org)
  • Protriptyline HCl, dibenzocycloheptene derivative, has a molecular weight of 299.84. (nih.gov)
  • When protriptyline is used to treat the depressive component of schizophrenia, psychotic symptoms may be aggravated. (wikipedia.org)
  • 5. Be cautious in administration of protriptyline and electro-convulsive shock therapy (ECT) simultaneously. (essentialsofmedicine.com)
  • Protriptyline may increase heart rate and stress on the heart. (wikipedia.org)
  • Like most antidepressants of this chemical and pharmacological class, protriptyline has also been used in limited numbers of patients to treat panic disorder, obsessive-compulsive disorder, attention-deficit/hyperactivity disorder, enuresis, eating disorders such as bulimia nervosa, cocaine dependency, and the depressive phase of bipolar disorder (manic-depressive) disorder. (wikipedia.org)
  • Protriptyline hydrochloride is not approved for use in pediatric patients. (nih.gov)
  • Do not stop taking protriptyline without talking to your doctor. (medlineplus.gov)
  • If you suddenly stop taking protriptyline, you may experience withdrawal symptoms such as nausea, headache, and lack of energy. (medlineplus.gov)
  • In rare cases in which patients with cardiovascular disease must take protriptyline, they should be monitored closely for cardiac rhythm disturbances and signs of cardiac stress or damage. (wikipedia.org)
  • Men with prostate enlargement who take protriptyline may be especially likely to have problems with urinary retention. (wikipedia.org)
  • Children younger than 18 years of age should not normally take protriptyline, but in some cases, a doctor may decide that protriptyline is the best medication to treat a child's condition. (medlineplus.gov)
  • You should know that your mental health may change in unexpected ways when you take protriptyline or other antidepressants even if you are an adult over age 24. (medlineplus.gov)
  • Take protriptyline at around the same times every day. (medlineplus.gov)
  • Take protriptyline exactly as directed. (medlineplus.gov)
  • Continue to take protriptyline even if you feel well. (medlineplus.gov)
  • How should I take protriptyline? (cigna.com)
  • Serious, life-threatening side effects can occur if you take protriptyline before the MAO inhibitor has cleared from your body. (healthyplace.com)
  • Protriptyline has been found in some studies to have a more rapid onset of action than imipramine or amitriptyline. (nih.gov)
  • In any of these circumstances, it may be advisable to reduce the dose of protriptyline or to use an antipsychotic drug concurrently. (wikipedia.org)
  • Your doctor will probably start you on a low dose of protriptyline and gradually increase your dose. (medlineplus.gov)
  • The doctor or pharmacist will give you the manufacturer's patient information sheet (Medication Guide) when you begin treatment with protriptyline. (medlineplus.gov)
  • Talk with your doctor if your symptoms do not improve during treatment with protriptyline. (healthyplace.com)
  • Anyone considering the use of protriptyline hydrochloride or any other antidepressant in a child, adolescent, or young adult must balance this risk with the clinical need. (nih.gov)
  • Protriptyline hydrochloride is not approved for use in pediatric patients. (nih.gov)
  • Protriptyline HCl is N -methyl-5H dibenzo[ a,d ]-cycloheptene-5-propanamine hydrochloride. (nih.gov)
  • Protriptyline hydrochloride, a dibenzocycloheptene derivative, has a molecular weight of 299.84. (nih.gov)
  • Protriptyline Hydrochloride Tablets USP are available for oral administration containing either 5 mg or 10 mg of protriptyline hydrochloride USP. (nih.gov)
  • Protriptyline hydrochloride is an antidepressant agent. (nih.gov)
  • Protriptyline hydrochloride is indicated for the treatment of symptoms of mental depression in patients who are under close medical supervision. (nih.gov)
  • Protriptyline hydrochloride is contraindicated in patients who have shown prior hypersensitivity to it. (nih.gov)
  • Protriptyline hydrochloride is contraindicated in patients taking cisapride because of the possibility of adverse cardiac interactions including prolongation of the QT interval, cardiac arrhythmias and conduction system disturbances. (nih.gov)
  • Protriptyline is a tricyclic antidepressant that is used to treat symptoms of depression. (cigna.com)
  • Protriptyline is a tricyclic antidepressant that was previously widely used in the therapy of major depression. (nih.gov)
  • Protriptyline is in a class of medications called tricyclic antidepressants. (medlineplus.gov)
  • Protriptyline may also be used for purposes not listed in this medication guide. (cigna.com)
  • Do not use this medication if you are allergic to protriptyline, or if you have recently had a heart attack. (healthyplace.com)
  • Read the Medication Guide provided by your pharmacist before you start taking protriptyline and each time you get a refill. (blinkhealth.com)
  • Protriptyline is used primarily to treat depression and to treat the combination of symptoms of anxiety and depression. (wikipedia.org)
  • Protriptyline is used to treat depression. (medlineplus.gov)
  • Protriptyline controls depression but does not cure it. (medlineplus.gov)
  • Like most antidepressants of this chemical and pharmacological class, protriptyline has also been used in limited numbers of patients to treat panic disorder, obsessive-compulsive disorder, attention-deficit/hyperactivity disorder, enuresis, eating disorders such as bulimia nervosa, cocaine dependency, and the depressive phase of bipolar disorder (manic-depressive) disorder. (wikipedia.org)
  • A small number of children, teenagers, and young adults (up to 24 years of age) who took antidepressants ('mood elevators') such as protriptyline during clinical studies became suicidal (thinking about harming or killing oneself or planning or trying to do so). (medlineplus.gov)
  • Protriptyline is in a group of drugs called tricyclic antidepressants. (healthyplace.com)
  • When it is desired to substitute protriptyline for a monoamine oxidase inhibitor, a minimum of 14 days should be allowed to elapse after the latter is discontinued. (nih.gov)
  • Do not use protriptyline if you have used an MAO inhibitor in the past 14 days. (cigna.com)
  • Do not use protriptyline if you have recently had a heart attack, or if you have taken cisapride (Propulsid) or used an MAO inhibitor such as isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam), or tranylcypromine (Parnate) within the past 14 days. (healthyplace.com)
  • TCAs including protriptyline are also used to reduce the incidence of recurring headaches such as migraine, and for other types of chronic pain. (wikipedia.org)
  • You may have withdrawal symptoms if you stop using protriptyline suddenly. (cigna.com)
  • Protriptyline, chronic tension-type headaches, and weight loss in women. (medscape.com)
  • Protriptyline affects chemicals in the brain that may become unbalanced. (healthyplace.com)
  • 19. The mechanism of protriptyline-induced Ca2+ movement and non-Ca2+-triggered cell death in PC3 human prostate cancer cells. (nih.gov)
  • Protriptyline shares side effects common to all TCAs. (wikipedia.org)
  • What are the possible side effects of protriptyline? (cigna.com)
  • If you have any of these conditions, you may not be able to use protriptyline, or you may need a dosage adjustment or special tests during treatment. (healthyplace.com)
  • Uniquely among most of the TCAs, protriptyline tends to be energizing instead of sedating, and is sometimes used for narcolepsy to achieve a wakefulness-promoting effect. (wikipedia.org)
  • If you need to have any type of surgery, tell the surgeon ahead of time that you are taking protriptyline. (healthyplace.com)
  • Store protriptyline at room temperature away from moisture and heat. (healthyplace.com)
  • A common problem with TCAs is sedation (drowsiness, lack of physical and mental alertness), but protriptyline is considered the least sedating agent among this class of agents. (wikipedia.org)