• Chromosomal alterations such as translocations, deletions and tandem duplications intersecting with insulated neighborhood anchor sites can activate oncogenes. (wikipedia.org)
  • Overexpression of the bcl-2 proto-oncogene in cultured sympathetic neurons has now been shown to prevent apoptosis normally induced by deprivation of nerve growth factor. (sciencemag.org)
  • In this investigation, we examined the role of the Axl proto-oncogene in renal cell carcinoma (RCC). (nih.gov)