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  • Binds
  • Fibulin-1 binds to a number of extracellular matrix constituents including fibronectin, nidogen-1, and the proteoglycan, versican. (wikipedia.org)
  • 5. The device of claim 1 wherein the reagent that specifically binds red blood cell surface antigens is selected from the group consisting of monoclonal antibody, polyclonal antibodies, and their F(ab') 2 , Fab' and Fab fragments. (google.com)
  • It is in this form that HS binds to a variety of protein ligands and regulates a wide variety of biological activities, including developmental processes, angiogenesis, blood coagulation, and tumour metastasis. (wikipedia.org)
  • Integrin
  • 2) Different from any other hematopoietic cells, ATL cells express a characteristic heparan sulfate capable of immobilizing heparin-binding chemokine macrophage inflammatory protein (MIP) -1beta, a potent T cell-integrin-trigger, produced by the cells themselves. (nii.ac.jp)
  • secretory
  • Proteoglycans stored in the secretory granules of many hematopoietic cells also contain a protease-resistant peptide core, which may be important for neutralizing hydrolytic enzymes. (genecards.org)
  • Full-length CYR61 protein contains 381 amino acids with an N-terminal secretory signal peptide followed by four structurally distinct domains. (wikipedia.org)
  • syndecans
  • The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. (wikipedia.org)
  • receptors
  • In general, FGFs stimulate a variety of cellular functions by binding to cell surface FGF-receptors in the presence of heparin proteoglycans. (wikipedia.org)
  • PSGAG inhibits the synthesis of prostaglandin E2, which is released upon joint injury and causes inflammation, increases the loss of proteoglycan, and reduces the threshold of pain receptors. (wikipedia.org)
  • filtration
  • As of 2017 many other roles for basement membrane have been found that include blood filtration and muscle homeostasis. (wikipedia.org)
  • metalloproteinases
  • Rempe RG, Hartz AM, Bauer B. Matrix metalloproteinases in the brain and blood-brain barrier: versatile breakers and makers. (springermedizin.de)
  • They also activate the skin's system (called metalloproteinases) that removes damaged proteins such as scars and sun damage marks. (anagen.net)
  • glycoproteins
  • The pregnancy-specific glycoproteins (PSGs) are the most abundant trophoblastic proteins in maternal blood during human pregnancy. (reactome.org)
  • Monosaccharides commonly found in eukaryotic glycoproteins include: The sugar group(s) can assist in protein folding or improve proteins' stability. (wikipedia.org)
  • Glycoproteins are important for white blood cell recognition, especially in mammals. (wikipedia.org)
  • Soluble glycoproteins often show a high viscosity, for example, in egg white and blood plasma. (wikipedia.org)
  • Metastasis
  • Our finding would warrant further studies that different proteoglycan and cytokine might bring enormous flexibility to the process of leukemic cell infiltration and tumor metastasis and would introduce new pharmacological approaches to control them. (nii.ac.jp)
  • novel
  • In this study, we investigated the effects of IL-1RA and a novel protein (IL-1RA-PEP) that was fused to IL-1RA with a cell penetrating peptide, on blood-brain barrier integrity, in male rats subjected to transient middle cerebral artery occlusion. (springermedizin.de)
  • molecules
  • The easiest answer to give is that each cell type, whether it is a skin cell or a white blood cell has a set of molecules on its outer surface which are found only on that cell. (madsci.org)