Cell SurvivalSurvival RateDisease-Free SurvivalApoptosisSurvivalSurvival AnalysisGraft SurvivalSignal TransductionCell Line, TumorTime FactorsTreatment OutcomeCells, CulturedCell ProliferationCell DeathKaplan-Meier EstimateProto-Oncogene Proteins c-aktRetrospective StudiesPhosphorylationProto-Oncogene ProteinsPhosphatidylinositol 3-KinasesProtein-Serine-Threonine KinasesCell LineAntineoplastic AgentsNeoplasm StagingRNA, Small InterferingProportional Hazards ModelsMice, Inbred C57BLBlotting, WesternFollow-Up Studiesbcl-X ProteinMice, KnockoutProto-Oncogene Proteins c-bcl-2bcl-Associated Death ProteinAntineoplastic Combined Chemotherapy ProtocolsImmunohistochemistryEnzyme ActivationBreast NeoplasmsLung NeoplasmsCombined Modality TherapyGene Expression Regulation, NeoplasticCaspase 3MutationPrognosisAutophagyNeoplasmsTransfectionCell DivisionCaspasesReverse Transcriptase Polymerase Chain ReactionTumor Cells, CulturedNF-kappa BCell DifferentiationMice, TransgenicModels, BiologicalRNA InterferenceRNA, MessengerApoptosis Regulatory ProteinsAdenocarcinomaEnzyme InhibitorsUp-RegulationTumor Suppressor Protein p53Gene Expression RegulationNeoplasm MetastasisDose-Response Relationship, DrugNeoplasm Recurrence, LocalIn Situ Nick-End LabelingCisplatinTumor Markers, BiologicalMultivariate AnalysisDNA-Binding ProteinsCell CycleGene Knockdown TechniquesDown-RegulationRadiation ToleranceDisease ProgressionChromonesDNA DamageCytoprotectionDrug Resistance, NeoplasmBrain NeoplasmsDisease Models, AnimalCell HypoxiaMorpholinesNeuronsTranscription FactorsDoxorubicinInhibitor of Apoptosis ProteinsOxidative StressLiver NeoplasmsGene ExpressionMembrane ProteinsMitogen-Activated Protein KinasesB-Cell Activating FactorMice, NudeMitochondriaMice, Inbred BALB CDose-Response Relationship, RadiationNeoplasm ProteinsGene Expression ProfilingB-Cell Activation Factor Receptor