Proteins that assemble. Medical search. Frequent questions

We have designed, synthesised and characterised a series of template-assembled de novo four-helix bundles, each differing in the linker length between the template and the peptides. (ubc.ca)
the creation of a large number of compounds (usually proteins or peptides) through technologies such as phage display . (genomicglossaries.com)
Peptides that self-assemble in ordered nanostructures are a particular case of supramolecular chemistry. (europa.eu)
Peptides possess the biocompatibility and chemical diversity found in proteins, being particularly interesting for regenerative medicine and nanomedicine. (europa.eu)
We use structure based modeling and computational protein design methods to optimize the protein sequence of proteins and peptides in order to control their assembly. (lu.se)

For example, self-assembly of lipid molecules and membrane proteins is crucial in defining cell architecture and enabling cell function 2 . (nature.com)
Later, the ordered protein chains can be labeled with fluorescent molecules and read under a microscope, allowing researchers to reconstruct the timing of the events. (311institute.com)
One way to study these functions is to image proteins, RNA, or other molecules inside the cells, which provide hints to what the cells are doing. (311institute.com)
This complex tags damaged and excess proteins with molecules called ubiquitin. (medlineplus.gov)
The cell membrane is a lipid bilayer that contains a wide variety of molecules mostly proteins and lipids. (protopage.com)
Through a nuanced balance of electrical and hydrophobic forces, biological molecules self-assemble into the large functional structures that maintain life's vital functions. (phys.org)
A synthetic, specially- designed oligonucleotide with the ability to recognize and bind a protein ligand molecule or molecules with high affinity and specificity. (genomicglossaries.com)
The basic format of the yeast-two hybrid system involves the creation of two hybrid molecules, one in which the " bait ' protein is fused with a transcription factor, and one in which the " prey " protein is fused with a related transcription factor . (genomicglossaries.com)
It does this by binding to a sequence of molecules called amino acids, which are then attached together to make a protein. (vetinfo.com)

In this work, we use single-molecule fluorescence microscopy to study the adsorption of α-lactalbumin protein on the glass substrate covered with a self-assembled monolayer (SAM) with varying surface concentrations. (aip.org)
A nanoscale modular design strategy was employed to synthesize six engineered, recombinant proteins intended to mimic aspects of the extracellular matrix proteins fibronectin, laminin, and elastin as well as the cell-cell adhesive protein neural cell adhesion molecule. (frontiersin.org)
A membrane protein is a protein molecule that is attached to, or associated with the membrane of a cell or an organelle. (phys.org)
RNA is the molecule that assembles proteins inside a cell. (vetinfo.com)
When a clindamycin molecule binds to a bacteria's RNA, that RNA molecule cannot bond to the proper sequence of amino acids, so it will not make the protein it was designed to for. (vetinfo.com)

Eisosomes are large protein complexes that are primarily composed of many subunits of two Bin-Amphiphysin-Rvs domain-containing proteins, Pil1 and Lsp1. (ox.ac.uk)
To achieve that, the research team came up with the idea of recording cellular events as a series of protein subunits that are continuously added to a chain. (311institute.com)
To create their chains, the researchers used engineered protein subunits, not normally found in living cells, that can self-assemble into long filaments. (311institute.com)
Each of these tags can bind to a different fluorescent antibody, making it easy to visualize the tags later on and determine the sequence of the protein subunits. (311institute.com)
The atomic interactions between subunits in protein assemblies are finely tuned to control affinity as well as quaternary structure. (lu.se)
Large protein assemblies are typically held together by weak interactions between individual components but the multiplicity of interactions among the large number of subunits can lead to exquisite specificity. (lu.se)
Linear POLYPEPTIDES that are synthesized on RIBOSOMES and may be further modified, crosslinked, cleaved, or assembled into complex proteins with several subunits. (bvsalud.org)

A research team at the University of Washington has harnessed complex computational methods to design customized proteins that can self-assemble into 120-subunit "icosahedral" structures inside living cells-the biggest, self-booting, intracellular protein nanocages ever made. (lifeboat.com)
icosahedral protein structures are commonly observed in natural biological systems for packaging and transport (e.g. viral capsids). (uw.edu)
In this paper, we show that these proteins self-assemble into higher-order structures and bind preferentially to phosphoinositide-containing membranes. (ox.ac.uk)
Guided by these structures, variants of the protein were designed to facilitate controlled assembly of protein nanostructures through the association of the toroids. (tue.nl)
Ubiquitin serves as a signal to specialized cell structures known as proteasomes, which attach (bind) to the tagged proteins and degrade them. (medlineplus.gov)
One of the potential strategies under development is to use virus-like-particles, which are protein-based structures that mimic viruses, to stimulate immune response. (laserfocusworld.com)
She has used code-breaking strategies to predict protein structures and applied computational techniques to drug discovery. (technologyreview.com)
We compared the S protein structures of MERS-CoV, SARS-CoV, and SARS-CoV-2 viruses and identified the residues like C526, C383, and N468 located in equivalent positions of these viruses have effects on S protein structure. (frontiersin.org)

Cells arrange their components-proteins, lipids, and nucleic acids-in organized and reproducible ways to optimize the activities of these components and, therefore, to improve cell efficiency and survival. (blogspot.com)
Separation of three lipidomes is exemplified: (i) Escherichia coli, (ii) SH‐SY5Y neuroblastoma cells, and (iii) lipids assembled in polymer nanodiscs. (researchgate.net)

However, subcellular organization is also important in prokaryotic cells, including rod-shaped bacteria such as E. coli , most of which lack such well-developed systems of organelles and motor proteins for transporting cellular cargoes. (blogspot.com)
As cells perform their everyday functions, they turn on a variety of genes and cellular pathways, and now in a new development in the field researchers from MIT have managed to coax cells to inscribing more of the history of these events in a long protein chain that can be imaged using a light microscope. (311institute.com)
With a typical cellular AND gate, the two necessary inputs activate proteins that together turn on expression of an output gene. (sciencedaily.com)
These regions, known as promoters, recruit the cellular proteins responsible for transcribing the GFP gene into messenger RNA, which then directs protein assembly. (sciencedaily.com)
Membrane proteins play a pivotal role in various cellular functions and are key targets for pharmaceutical interventions. (phys.org)
Currently, I work on topics such as protein folding in cellular environments, protein aggregation, and phase separation of biomolecular condensates. (lu.se)

The 1,384-amino acid protein, also designated p190 or CASPR for 'contactin-associated protein,' includes an extracellular domain with several putative protein-protein interaction domains, a putative transmembrane domain, and a 74-amino acid cytoplasmic domain. (nih.gov)
Gap junctions are composed of transmembrane connexin proteins. (jove.com)
[ 7 ] Connexins are a family of transmembrane proteins that assemble into hexameric hemichannels and form gated intercellular gap junction channels. (medscape.com)

The 2023 Photonics-Enabled Cloud Computing Summit assembled by Optica took an aggressive approach to calling out the limitations of today's current technologies. (laserfocusworld.com)

RNA 3 is required for the synthesis of the protein responsible for cell-to-cell movement. (wikipedia.org)
TRNT1 deficiency is caused by mutations in the TRNT1 gene, which provides instructions for making a protein involved in the production (synthesis) of other proteins. (medlineplus.gov)
Without the modification, tRNAs are thought to be less able to participate in protein synthesis. (medlineplus.gov)
We make use of a highly flexible multi-step cloning strategy in order to allow for the rapid synthesis of new recombinant proteins that can introduce many different biofunctionalities. (frontiersin.org)
Clindamycin is a lincosamide antibiotic, which means that it helps to remove an anaerobic bacterial infection by disrupting the synthesis of proteins that the bacteria need in order to continue to survive and grow. (vetinfo.com)
Clindamycin works by disrupting the synthesis of certain bacterial proteins, which are only created by specific kinds of anaerobic bacteria. (vetinfo.com)

Virions assemble. (wikipedia.org)
2021). Virus-like particles (VLP), self-assembled HPV L1+L2 protein capsids that resemble intact virions, are used as antigen in the assay. (cdc.gov)

The structural specificity of this two glycine variant is comparable to that of other known native-like de novo proteins. (ubc.ca)
Nipah virus has three structural proteins: a matrix protein that provides structure, and two envelope proteins that enable the virus to attach and fuse with host cells. (laserfocusworld.com)
Structural proteins are attached to microfilaments in the cytoskeleton which ensures stability of the cell. (phys.org)
An increase in intake of vitamin C will also aid the healing process, as one of the main components in the structural proteins that make up the ligament is collagen. (home-remedies-for-you.com)
The coiled coil is one of most recurring structural motifs in eucarytotic proteins, found in for example transcription factors, motor and skeletal proteins. (lu.se)

The TRNT1 protein modifies tRNAs, which allows the correct amino acid to be attached to each tRNA. (medlineplus.gov)
Most of these mutations substitute one protein building block (amino acid) for another amino acid in the cullin-7 protein or result in a cullin-7 protein that is abnormally short and nonfunctional. (medlineplus.gov)
This mutation replaces the amino acid glutamine with a premature stop signal in the instructions for making the cullin-7 protein (written as Gln1553Ter or Q1553X), leading to production of an abnormally short protein. (medlineplus.gov)
This protein is 1,353 amino acids in length, and the monomers assemble to form a homotrimer. (frontiersin.org)
Amino acids converted from proteins are important in assembling new tissue. (home-remedies-for-you.com)
The specific sequence of AMINO ACIDS determines the shape the polypeptide will take, during PROTEIN FOLDING, and the function of the protein. (bvsalud.org)

The work, funded by DARPA in a lead-up to the new INTERfering and Co-Evolving Prevention and Therapy (INTERCEPT) program, "opens the door to a new generation of genetically programmable protein-based molecular machines," the researchers report in this week's issue of the journal Science. (lifeboat.com)
Both experimental and molecular dynamics simulation results show that peptoids assemble into membranes through an anisotropic formation process. (nature.com)
Revealing how molecular interactions are optimized to control both oligomerization state and assembly pathway in protein assemblies is of vital importance for our understanding of biomedically important biological assemblies, as well as for efforts to manipulate them. (lu.se)
Our goal is to achieve molecular level control of protein self-assembly. (lu.se)
Our facilities provide the opportunity to study protein structure, molecular probes and drug design, system biology and molecular interactions in cells and tissues. (lu.se)
With the help of various forms of mass spectrometry, synchrotron radiation, protein production & labelling, and bioinformatics, our facilities provide the opportunity to study protein structure and dynamics, molecular probes and drug design. (lu.se)

It has been known that liquiritin from licorice forms complexation with aconitine and therefore reduces the amount of free aconitine [ 7 ], indicating that interactions between aconitine with other major amphiphilic compounds (i.e., protein) from licorice may facilitate the formation of aconitine complex of such kind, too. (springer.com)
Our studies suggest that controlling hydrophobicity and roughness, in addition to electrostatics, as independent parameters could provide a means to tune desirable or undesirable protein interactions with surfaces. (aip.org)
Random lateral protein diffusion and protein-protein interactions are probably sufficient to generate the observed complex, ordered patterns. (blogspot.com)
Moreover, the aromatic residue N 4-Cl pe was chosen because it is known to stabilize self-assembled materials by enhancing intermolecular packing through, for example, π - π interactions 16 . (nature.com)
Receptor-ligand and parasite protein-protein interactions in Plasmodium vivax: Analysing rhoptry neck proteins 2 and 4 por: Bermúdez M., et al. (ccb.org.co)
Therefore, this engineered protein adsorption approach allows for the facile preparation of tunable, quantifiable, and reproducible surfaces for in vitro studies of cell-ligand interactions and for potential application as coatings on neural implants. (frontiersin.org)
co-immunoprecipitation Used to determine protein- protein interactions . (genomicglossaries.com)
Repeat proteins feature prominently in biology and serves as a diverse scaffold for protein-protein interactions. (lu.se)

Cullin-7 helps assemble a complex known as an E3 ubiquitin ligase. (medlineplus.gov)

IPD researchers in the Baker group have published in Science a paper entitled "Computational design of self-assembling protein nanomaterials with atomic level accuracy. (uw.edu)
They describe a general computational method for designing proteins that self-assemble to a desired symmetric architecture. (uw.edu)
Such simulations take immense computational power, but they're worth it: knowing how a protein folds is key to understanding a number of ailments like mad cow disease and cystic fibrosis, which are believed to result when proteins misfold. (technologyreview.com)
We use computational protein design methods to change protein sequence in order to modify the oligomerization properties of coiled coils. (lu.se)
Rämisch S, Weiniger U, Martinsson J, Akke M and Andre I "Computational design of Leucine-Rich Repeat proteins with a defined geometry" Proc Natl Acad Sci, 2014, pii: 201413638. (lu.se)

Actually, thousands of home computers today are being tapped to do research, helping biologists process gigabytes of data on genes and proteins. (technologyreview.com)
Transcription and translation Genes are segments of deoxyribonucleic acid (DNA) that contain the code for a specific protein that functions in one or more types of cells in the body or the code for functional ribonucleic. (msdmanuals.com)
Its genome encodes three distinct cellulose synthases (CS), bcsAB1, bcsAB2, and bcsAB3, which together with genes for accessory proteins are organized in operons of different complexity. (bvsalud.org)
Below is a non-exhaustive list of in-house infrastructures that are categorized into three overarching themes: bio-imaging, proteins, genes & cells and other resources. (lu.se)
In addition to infrastructures for bioimaging, protein and genes & cells, we also provide other resources e.g., databases, networks and specialized labs. (lu.se)

The capsid protein remains attached to the coat protein binding site (CPB) at the 3'- end of the RNAs. (wikipedia.org)
Both are composed of type-specific HPV L1 protein, the major capsid protein of HPV. (cdc.gov)
and capsid protein VP2 (VP2) gene, partial cds. (cdc.gov)

The ephedrine alkaloid-containing colloidal nanoparticles discovered in another licorice containing Chinese medicinal decoction [ 12 ] imply that licorice root proteins would hypothetically interact with aconitine to form aggregates thereafter affecting the toxicity. (springer.com)
Surface morphology, in addition to hydrophobic and electrostatic effects, can alter how proteins interact with solid surfaces. (aip.org)
More than half of all proteins interact with membranes. (phys.org)
Cell recognition proteins allow cells to identify each other and interact. (phys.org)
If the bait and prey proteins indeed interact then the two factors fused to these two proteins are also brought into proximity with each other. (genomicglossaries.com)

1,2 In 2019, the National Academies of Sciences challenged researchers to design new surface materials as part of understanding protein adsorption and dynamics in realistic complex environments. (aip.org)
Researchers from the United States have discovered that bacterial proteins self-assemble stochastically (that is: randomly) and not directed by any centralized force of any sort. (blogspot.com)
In a proof-of-concept study, researchers have created self-assembled, protein-based circuits that can perform simple logic functions. (sflorg.com)
Chemistry professor Keng Chou and his team of researchers from UBC and Cornell University (Ithaca, NY) used a superresolution microscope patented by UBC to observe whether viruses actually assemble in the way scientists have hypothesized. (laserfocusworld.com)
Below you can see some examples of the infrastructure for proteins, available for researchers at Lund University. (lu.se)

citation needed] Beside encapsidation and its role in movement, the viral coat protein plays a role in the initiation of RNA replication. (wikipedia.org)
5th step: Plus- strand RNAs and viral proteins are synthesized. (wikipedia.org)
On the other hand, an increase in N (viral protein) was observed. (wikipedia.org)
Vaccines work by exposing a person to a small amount of modified virus or viral proteins, which rallies the body's natural defense. (laserfocusworld.com)
We investigated the effects of MERS-CoV S protein viral mutations on protein stability and binding affinity. (frontiersin.org)
Viral proteins are synthesized 2 to 14 days after the infection and self-assemble within the cytoplasm. (medscape.com)

These proteins target foreign invaders such as bacteria and viruses and mark them for destruction. (medlineplus.gov)
Biologists at the U.S. Department of Energy's Brookhaven National Laboratory and their collaborators have discovered an aberrant protein that's deadly to bacteria. (sflorg.com)
The newly discovered protein could serve as a model to help scientists unravel details of those drugs' lethal effects on bacteria-and potentially point the way to future antibiotics. (sflorg.com)
We've identified a single protein that mimics the effect of a complex mixture of aberrant proteins made when bacteria are treated with aminoglycosides. (sflorg.com)
Here we show that Escherichia coli bacteria expressing fibrous surface proteins, known as curli, assemble and activate factors of the human coagulation cascade at their surface. (lu.se)

In this study, a boiling-stable 31-kDa protein (namely GP) was purified from licorice and self-assembled into nanoparticles (206.2 ± 2.0 nm) at pH 5.0, 25 °C. The aconitine-encapsulated GP nanoparticles (238.2 ± 1.2 nm) were prepared following the same procedure and tested for its toxicity by intraperitoneal injection on ICR mouse ( n = 8). (springer.com)

Self-assembling functional pro. (ccb.org.co)
TRNT1 gene mutations lead to a shortage (deficiency) of functional TRNT1 protein. (medlineplus.gov)
Scientists have believed that matrix proteins recruit envelope proteins, sending out some sort of signal so they can all join together on the cell membrane and become a functional virus. (laserfocusworld.com)
This produces virus particles more quickly than previously envisioned, but many matrix proteins don't pick the envelope proteins up at all, and don't become functional viruses. (laserfocusworld.com)
In addition, we studied all DPP4 mutations and found the functional substitution R336T weakens both DPP4 protein stability and S-DPP4 binding affinity. (frontiersin.org)

Understanding the heterogeneous dynamics of protein adsorption on surfaces with varying roughness is experimentally challenging. (aip.org)
Physical adsorption isotherms were experimentally determined for these engineered proteins, allowing for direct calculation of the available ligand density present on coated surfaces. (frontiersin.org)
The redesigned proteins are then characterized experimentally. (lu.se)
The biophysical properties of the designed proteins are then experimentally tested in the lab. (lu.se)

A new paper is out in the June 5 issue of Nature entitled Accurate design of co-assembling multi-component protein nanomaterials. (uw.edu)
An ability to develop sequence-defined synthetic polymers that both mimic lipid amphiphilicity for self-assembly of highly stable membrane-mimetic 2D nanomaterials and exhibit protein-like functionality would revolutionize the development of biomimetic membranes. (nature.com)
Herein we report the first example of self-assembling highly stable and self-repairing membrane-mimetic 2D nanomaterials by designing lipid-like sequence-defined peptoids. (nature.com)

Spatial organization of membranes into domains of distinct protein and lipid composition is a fundamental feature of biological systems. (ox.ac.uk)
Biological membranes consist of a phospholipid bilayer and a variety of proteins that accomplish vital biological functions. (phys.org)

Ribosomes assemble proteins and polypeptides for cell division. (protopage.com)

The architecture of its extracellular domain is similar to that of neurexins, and this protein may be the signaling subunit of contactin, enabling recruitment and activation of intracellular signaling pathways in neurons. (nih.gov)
Scientists have found that extracellular calcium mediates the activation of a membrane protein that waves the flag signaling cell death. (phys.org)

Pande's group is folding an intestinal protein, which assembles in 10,000 nanoseconds. (technologyreview.com)

The immunodeficiency is characterized by low numbers of immune system cells called B cells, which normally help fight infections by producing immune proteins called antibodies (or immunoglobulins). (medlineplus.gov)
A key building block of life, actin is one of the most abundant and highly conserved proteins in eukaryotic cells. (phys.org)
This protein forms into filaments that help make up the skeleton of cells, giving them shape. (phys.org)
Bacterial pathogens like Salmonella, Shigella, Listeria and many others exploit the protein skeleton of the cells they infect in order to spread throughout the host. (phys.org)
If a vaccine contains a large percentage of virus-like particles that have only the matrix protein but not the envelope proteins, it won't trigger a strong immune response to the proteins that are most essential for helping a virus enter cells,' says Qian Liu, a postdoctoral fellow in UBC's chemistry department who was lead author of the study. (laserfocusworld.com)
As confirmation that ligand density in these engineered systems impacts neuronal cell behavior, we demonstrate that increasing the density of fibronectin-derived RGD ligands on coated surfaces while maintaining uniform protein surface coverage results in enhanced neurite extension of PC-12 cells. (frontiersin.org)
Folding@Home uses otherwise-idle CPU and GPU time on your computer(s) to solve protein-folding models via distributed computing: 'Folding refers to the way human protein folds in the cells that make up your body. (sjgames.com)
Gap junctions are specialized protein channels that connect the cytoplasms of adjacent cells. (jove.com)
In animal cells, gap junctions are formed when a set of six proteins called connexins arrange themselves to form a cylindrical structure within the plasma membrane. (jove.com)
And you instruct the cells to make the protein or proteins that you need. (medscape.com)

Mutations in the CUL7 gene, including the Gln1553Ter mutation, prevent the cullin-7 protein from bringing together the components of the E3 ubiquitin ligase complex, interfering with the process of tagging unneeded proteins for degradation. (medlineplus.gov)
The goal of the present investigation is to examine the effects of missense mutations in the MERS-CoV S protein on protein stability and binding affinity with DPP4 to provide insight that is useful in developing vaccines to prevent coronavirus infection. (frontiersin.org)
These findings provide further information on how mutations in coronavirus S proteins effect protein function. (frontiersin.org)
The finding of mutations in GJB3 , GJB4 , and GJA1 suggests that the clinical manifestations of EKVP are caused by impaired gap junctional intercellular communication or hemichannel function owing to a dominant effect of mutant gap junction proteins. (medscape.com)

The CUL7 gene provides instructions for making a protein called cullin-7. (medlineplus.gov)
The gene product was initially identified as a 190-kD protein associated with the contactin-PTPRZ1 complex. (nih.gov)

A key component in the virulence of MERS-CoV is the Spike (S) protein, which binds with the host membrane receptor dipeptidyl peptidase 4 (DPP4). (frontiersin.org)

Our data suggest that the mechanism of membrane organization by eisosomes is mediated by self-assembly of its core components into a membrane-bound protein scaffold with lipid-binding specificity. (ox.ac.uk)

The SNARE complex assembles from vesicular Synaptobrevin-2 as well as Syntaxin-1 and SNAP25 both anchored to the presynaptic membrane. (researchgate.net)
Even if a protein is very complex in structure, which could be a limitation in recombinant, because your body makes it, it knows how to do it. (medscape.com)
The C5b-C6 complex is the foundation upon which the lytic complex is assembled. (lu.se)

When exposed to biological medium or multiple composition dispersions like herbal decoction, protein corona formed on the nanoparticles (NPs) diversely alters the biological fate and pharmaceutical efficacy of particles [ 10 ]. (springer.com)
Expression of the L1 protein using recombinant DNA technology produces noninfectious virus-like particles (VLPs). (cdc.gov)

The proteins are synthesized using recombinant, genetic engineering techniques, allowing for the creation of biocompatible polymers with nanoscale precision that impart highly specific protein functionalities. (frontiersin.org)

New technologies for purifying membrane-bound protein complexes in combination with cryo-electron microscopy (EM) have recently allowed the exploration of such complexes under near-native conditions. (researchgate.net)
Rotor ATPases are large multisubunit membrane protein complexes found in all kingdoms of life. (jyu.fi)

In this study, OJPs extracted and fractionated from Ophiopogon japonicus were used to prepare OJPs/chitosan (CS)/whey protein (WP) co-assembled nanoparticles. (tmu.edu.tw)

Misfolding of proteins sometimes leads to the formation of certain type of aggregates, amyloids, which can cause diseases such as Alzheimer's, ParkinsonÕs, type II diabetes and Creutzfeldt-Jakob. (lu.se)

The intracellular protein extracts of a fungal strain Pycnoporus sanguineus was used as reducing and stabilizing agents to synthesize AuNPs with various shapes and dimensions, which present good catalyzing ability on the degradation of 4-nitroaniline [ 11 ]. (springer.com)

Inside the leading edge of a crawling cell, intricate networks of rod-like actin filaments extend toward the cell membrane at various angles, lengthening protein by protein. (phys.org)

Increasing or decreasing the linker length by one glycine residue had a significant effect on the structure and properties of the template-assembled synthetic proteins (TASPs). (ubc.ca)
Biopolymers, such as proteins, DNA, and polysaccharides, which are available in almost unlimited quantity in nature, as well as many synthetic polymers, which are industrially produced on a large scale, belong to this fascinating class of polymers. (mdpi.com)

In particular, cullin-7 is thought to help regulate proteins involved in the body's response to growth hormones, although its specific role in this process is unknown. (medlineplus.gov)

Stanford University chemist Vijay Pande has launched Folding@home , a program that simulates the way proteins self-assemble or "fold" into a three-dimensional shape. (technologyreview.com)
We rely on the proteins to keep us healthy and they assemble themselves by folding. (sjgames.com)

Peroxiredoxins (Prxs) are a protein family that shows an amazing array of supramolecular assemblies, making them attractive tectons. (tue.nl)

Due to the wide range of binding targets, their large interaction surfaces and biophysical properties, LRR proteins have been suggested as alternatives to antibodies as scaffolds for protein binding. (lu.se)

The Golgi Apparatus sorts, modifies, and packages proteins and other materials from the endoplasmic reticulum for storage in the cell or secretion outside the cell. (protopage.com)

Although transcription of bcsAB3 was observed, expression of the protein was below the detection limit of proteome analysis. (bvsalud.org)

RNA 1 and 2 encode proteins needed for replication. (wikipedia.org)

Such proteins are involved in immune response, for example. (phys.org)

The virion has a capsid (coat protein) but no envelope. (wikipedia.org)
However, Chou and his team observed that envelope proteins tend to be scattered randomly on the cell membrane. (laserfocusworld.com)

In a paper just published in the journal PLOS ONE , the scientists describe how this erroneously built protein mimics the action of aminoglycosides, a class of antibiotics. (sflorg.com)

Encapsulation of poisonous alkaloids into self-assembled herbal protein nanoparticles contributes to toxicity attenuation of combined use of herbs, implying a prototype nanostructure and a universal principle for the safer clinical applications of herbal medicines. (springer.com)

Organisms6

Technology, Industry, Agriculture3

Information Science1

Peptides5

Molecules9

Molecule5

Subunits7

Structures8

Lipids2

Cellular6

Transmembrane3

20231

Synthesis6

Virions2

Structural5

Amino6

Molecular6

Interactions8

Helps assemble1

Computational5

Genes5

Capsid protein3

Interact5

Researchers5

Viral6

Bacteria5

Boiling-stable1

Functional5

Experimentally4

Nanomaterials3

Membranes2

Ribosomes1

Extracellular2

Intestinal1

Cells10

Mutations4

Gene2

Binds1

Lipid1

Complex3

Particles2

Recombinant1

Complexes2

Whey protein1

Aggregates1

Intracellular1

Filaments1

Synthetic2

Body's1

Folding2

Assemblies1

Antibodies1

Modifies1

Transcription1

Encode1

Immune1

Envelope2

Scientists1

Nanoparticles1