It forms a checkpoint protein complex with RAD1 and HUS1. (avivasysbio.com)
This complex is recruited by checkpoint protein RAD17 to the sites of DNA damage, which is thought to be important for triggering the checkpoint-signaling cascade. (avivasysbio.com)
Adaptor2
Conversely the dynamin-related protein 1 (Drp1/DNM1) is definitely a cytosolic protein recruitment of which to the OMM from the anchored fission 1 protein (Fis1p/FIS1) adaptor initiates and settings the fission and distribution of mitochondria in cells [19]. (tech-strategy.org)
The ABL1 protooncogene encodes a cytoplasmic and nuclear protein tyrosine kinase that has been implicated in processes of cell differentiation, cell division, cell adhesion, and stress response. (affbiotech.cn)
Activity of c-Abl protein is negatively regulated by its SH3 domain, and deletion of the SH3 domain turns ABL1 into an oncogene. (affbiotech.cn)
RefSeq1
Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. (avivasysbio.com)
Atrophy1
These proteins act together with the optic atrophy protein 1 (OPA1) and an inner mitochondrial membrane (IMM) located dynamin-like GTPase mutated in heritable optical atrophy [18]. (tech-strategy.org)
Genes up-regulated in comparison of dendritic cells (DC) stimulated with LPS (TLR4 agonist) at 16 h versus DC cells stimulated with Pam3Csk4 (TLR1/2 agonist) at 16 h. (gsea-msigdb.org)
Research with yeast resulted in the identification from the conserved mammalian "mitochondria-shaping" protein. (tech-strategy.org)
Search1
Previously NKP608 we recognized the Carboxy-Terminal Modulator Protein (CTMP) inside a two-hybrid search for PKB/Akt binding partners [20]. (tech-strategy.org)
Target1
XLS 97 kb) 12861_2017_153_MOESM8_ESM.xls (98K) GUID:?B2FE5241-0444-4D48-99D4-D5E55E4120EF Extra file 9: Desk S7: Target genes of the very best portrayed 18 miRNAs. (clinical-research-informatics.com)
Expression1
Chromatin modifier metastasis-associated protein 1 (MTA1), closely associated with tumor angiogenesis in breast cancer, plays an important role in gene expression and cancer cell behavior. (mcw.edu)
Wang G, Li Y, Wang T, Wang J, Yao J, Yan G, Zhang Y, Lu H. Multi-comparative Thermal Proteome Profiling Uncovers New O -GlcNAc Proteins in a System-wide Method. (mcw.edu)
Cell1
O-linked N -acetylglucosamine ( O -GlcNAc) is a prevalent protein modification that plays fundamental roles in both cell physiology and pathology. (mcw.edu)
Found1
This protein is found to possess 3' to 5' exonuclease activity, which may contribute to its role in sensing and repairing DNA damage. (avivasysbio.com)
The Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway evaluation suggested that furthermore to Wnt and changing growth aspect (TGF) signaling pathways, that have been reported in response to follicle formation broadly, another mixed band of signaling pathways that regulate lipid synthesis and fat burning capacity, like the phosphatidylinositol signaling program and glycerolipid signaling and fat burning capacity, are Gemzar biological activity in charge of follicle formation also. (clinical-research-informatics.com)
Profusion protein like the dynamin-related proteins mitofusins 1 and 2 (Mfn1 and Mfn2) are essential the different parts of the external mitochondrial membrane (OMM) essential to mitochondria tethering and fusion [16] [17]. (tech-strategy.org)
Among diverse protein post-translational modifications, O -GlcNAcylation, a simple but essential monosaccharide modification, plays crucial roles in cellular processes and is closely related to various diseases. (mcw.edu)
Alternative1
Use of alternative polyA sites has been noted for this gene. (avivasysbio.com)