Proteins principal component analysis. Medical search. Frequent questions

Comparing HESC controls with HESCs deficient in SRC-3, gene enrichment analysis of the differentially expressed gene set revealed an overrepresentation of genes involved in chromatin remodeling, cell proliferation/motility, and programmed cell death. (frontiersin.org)
Comparative analysis within each field revealed a total of 32 differentially expressed proteins between GM and non-GM samples, and their molecular functions were mainly assigned to carbohydrate and energy metabolism, genetic information processing and stress response. (biosafety-info.net)
To the best of our knowledge this study represents the first evidence of protein identities with differentially expressed isoforms in Brazilian MON810 genetic background hybrid grown under field conditions. (biosafety-info.net)
Our results show many differentially expressed proteins in diseased and control animals, some at early stages of disease. (biomedcentral.com)

A cocktail of five recombinant proteins optimized for conserved GI nematode targets was used immunize pigs and test for active antibody responses in both the serum and intestinal ileal fluid of immunized pigs. (frontiersin.org)

One approach tries to identify motifs recognized by the sorting proteins and receptors of the protein transport machinery to move protein products from the cytosol to other subcellular locations [ 6 ]. (biomedcentral.com)

This project presents an up-to-date collection of newly obtained ROA spectra of a large number of proteins across a range of structural class types. (gla.ac.uk)
For stage one, we trained multiple Support Vector Machines (SVMs) to score eukaryotic protein sequences for membership to each of three categories: nuclear, cytoplasmic and extracellular, plus extra category nucleocytoplasmic, accounting for the fact that a large number of proteins shuttles between those two locations. (biomedcentral.com)

This resource, combining a unique new dataset and novel application of analysis methods to multiple relevant datasets, identifies numerous potential drug targets for manipulating circuit function, reveals neuron subtype-specific roles for disease-linked genes, and is useful for understanding gene expression changes observed in human patient brains. (jneurosci.org)
The total of studied whey proteins (WPT) in dairy beverages based on Zonar milk serum varied between 1.42 g/L and 3.04 g/L. The results obtained were evaluated by principal component analysis (PCA) for correlation between the types of studied dairy beverages (natural and with additives added), the HPLC dataset of four whey proteins and WPT (active variables) to differentiate type of dairy beverages samples. (tubitak.gov.tr)
Using a principal component analysis to simplify the complexity of the data, the researchers found that three principal components accounted for one-third of the phenotypic variability in their dataset, emphasizing that despite the complexity of the data, informative clinical groups can be derived. (eurekalert.org)
In the first stage of the analysis, the main sources of variation in the dataset were identified by using Principal Components Analysis which correlated most of the variation to the different agroecosystems conditions. (biosafety-info.net)

These result in imbalances in the connectivity of neuronal circuitry, and also negatively impact the intracellular connectivity of neuronal proteins and protein pathways, contributing to cognitive decline associated with AD 6 . (nature.com)
When these coupled residues form pathways linking functionally important parts of a protein, they may participate in allosteric signaling. (wikipedia.org)
Then, the DEGs were analysed to identify biological pathways of dental pulp inflammation with Gene Ontology (GO) analysis, Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment analysis and Gene Set Enrichment Analysis (GSEA). (researchsquare.com)
GO analysis revealed that the DEGs were enriched in biological processes related to inflammation, and the enriched pathways in the KEGG pathway analysis were cytokine-cytokine receptor interaction, chemokine signalling pathway and NF-κB signalling pathway. (researchsquare.com)

Therefore computational prediction of protein features from their sequence is often used for designing strategies for experimental characterization of proteins and is also important for genome annotation and drug target identification [ 4 , 5 ]. (biomedcentral.com)
Extensive characterization including infrared and X-ray spectroscopy, thermogravimetric analysis, size, charge, surface area, and density captured the alteration in physicochemical properties as the material went through sequential purification. (cdc.gov)

Proteins that activated immunity are potential antigens for immunization and the multi-omics phylum-spanning prioritization database that was created is a valuable resource for identifying target proteins in a wide array of different parasitic nematodes. (frontiersin.org)
14-3-3 proteins are known to regulate diverse processes via binding phosphorylated target proteins in all eukaryotes [ 1 - 5 ]. (biomedcentral.com)
The most intensively characterized 14-3-3 target proteins are nitrate reductase and H + -ATPase. (biomedcentral.com)

CsrRS (or CovRS) is a two-component system implicated in the control of multiple virulence determinants in the important human pathogen, group A Streptococcus (GAS). (lu.se)

The cross-correlation matrix obtained from MD simulation trajectory provided important information regarding the anisotropy of backbone dynamics that leads to unfolding and was applied to give a new insight to protein dynamics. (typeset.io)
To identify the correlation in dynamics among various secondary structural fragments and also the individual contribution of different residues towards thermal unfolding, principal component analysis method was applied in order to give a new insight to protein dynamics by analyzing the contribution of coefficients of principal components. (typeset.io)
The development of the analysis of ROA spectra has largely been based upon the correlation of ROA spectra of proteins of known structure with structural information from alternative sources, chiefly X-ray crystallography and multidimensional nuclear magnetic resonance (NMR). (gla.ac.uk)
With a basis for the correlation between the ROA spectrum and the known crystal structure (or NMR structure) being well established, it is possible to interpret the ROA spectra of proteins that do not have (for whatever reason) well defined structures. (gla.ac.uk)
Correlation and principal component analysis consistently aggregate iPSCs and iPSC EVs but segregate PD-MSC and their EVs. (unlp.edu.ar)

This revealed which proteins had changed location, identifying these proteins as important for the cell's response to the growth factor. (elifesciences.org)
The cell's functional machinery - proteins - need to be present at specific cellular compartments so that cells can function properly. (biomedcentral.com)

We also apply our analysis to two other relevant datasets for comparison, and provide a searchable website for convenient access to the resource. (jneurosci.org)
Next, we compared both datasets and found that while iPSC EVs enclose proteins that modulate RNA and microRNA stability and protein sorting, PD-MSC EVs are rich in proteins that organize extracellular matrix, regulate locomotion, and influence cell-substrate adhesion. (unlp.edu.ar)

Subcellular localization critically influences protein function, and cells control protein localization to regulate biological processes. (elifesciences.org)
In order to regulate protein activity, many biological processes involve changes in protein subcellular localization. (elifesciences.org)

In plants, 14-3-3 proteins have major roles as regulators of nitrogen and carbon metabolism, conclusions based on the studies of a few specific 14-3-3 targets. (biomedcentral.com)
In this study, extensive novel roles of 14-3-3 proteins in plant metabolism were determined through combining the parallel analyses of metabolites and enzyme activities in 14-3-3 overexpression and knockout plants with studies of protein-protein interactions. (biomedcentral.com)
Plant 14-3-3 proteins are mainly thought to be regulators of carbon and nitrogen metabolism [ 2 ]. (biomedcentral.com)

Dynamic Organellar Maps enable the proteome-wide analysis of physiological protein movements, without requiring any reagents specific to the investigated process, and will thus be widely applicable in cell biology. (elifesciences.org)
These structures provide the backbone upon which proteome-wide connectivity, and in turn, protein networks become disturbed and ultimately dysfunctional. (nature.com)

Protein location can be predicted either from the sequence of a protein alone by identification of targeting peptide sequences and motifs, or by homology to proteins of known location. (biomedcentral.com)
A third approach, which is complementary, exploits the differences in amino acid composition of proteins associated to different cellular locations, and can be useful if motif and homology information are missing. (biomedcentral.com)
A ) Deletion of myosin tail homology domain of the CEP290 protein in rd16 mice compared to the wild-type (WT). (elifesciences.org)

As a first attempt to address this outstanding issue, we examine here the folding of ubiquitin, a 76-residue-long protein found in all eukaryotes that is known experimentally to fold on a millisecond timescale. (typeset.io)
14-3-3 proteins are considered master regulators of many signal transduction cascades in eukaryotes. (biomedcentral.com)

In this work, we used a label-free liquid chromatography tandem mass spectrometry proteomic approach to identify the most abundant proteins in EVs that are secreted from MSCs derived from PSCs (PD-MSCs) and from their parental induced PSCs (iPSCs). (unlp.edu.ar)
In the present study, we used two-dimensional gel electrophoresis combined with mass spectrometry to evaluate protein expression of Brazilian genetically modified maize hybrid grown under different agroecosystems conditions. (biosafety-info.net)
This "proof of concept" study, examines the use of differential protein expression profiling using surface enhanced laser desorption and ionisationtime of flight mass spectrometry (SELDI-TOF) for the diagnosis of TSE disease. (biomedcentral.com)

The researchers used a proteomic approach to evaluate protein expression of MON810 maize hybrids grown under different agroecosystem conditions in Brazil. (biosafety-info.net)

Proteins are generally thought to adopt unique structures determined by their amino acid sequences. (wikipedia.org)
Portions of protein structures often deviate from the equilibrium state. (wikipedia.org)
Many residues are in close spatial proximity in protein structures. (wikipedia.org)
Domain motions can be inferred by comparing different structures of a protein (as in Database of Molecular Motions), or they can be directly observed using spectra measured by neutron spin echo spectroscopy. (wikipedia.org)
This means that ROA spectroscopy can provide invaluable structural information for proteins that are precluded from analysis by other techniques, and also cast new light on the structures of proteins that have not been well defined. (gla.ac.uk)
Here, we present a comprehensive analysis of 15 isomorphous, high resolution crystal structures of the enzyme phosphoglucomutase from the bacterium Xanthomonas citri . (rcsb.org)
In addition, we use principal component analysis to examine various subsets of these structures with two goals: (1) identifying sites of conformational heterogeneity through a comparison of room temperature and cryogenic structures of the apo-enzyme and (2) a priori clustering of the enzyme-ligand complexes into functionally related groups, showing sensitivity of this method to structural features difficult to detect by traditional methods. (rcsb.org)
These structures also reveal the agonist-induced conformational changes propagated to the G-protein-coupling interface during activation. (bvsalud.org)

Current technical limitations curb our ability to explore global changes in protein level connectivity, restricting how to translate key network changes into AD therapies. (nature.com)
The authors conclude that while the detection of changes in protein profiles does not present a safety issue per se, further studies should be conducted in order to assess the biological relevance and implications of such changes. (biosafety-info.net)

Protein function is critically determined by subcellular localization, as organelles offer different chemical environments and interaction partners. (elifesciences.org)
In this study we explored the relationship between residue exposure and protein subcellular location. (biomedcentral.com)
In particular, the computational prediction of subcellular location from protein sequence information has been attempted mainly using three approaches. (biomedcentral.com)

We observed CsrS-dependent regulation of 72 of the 73 genes whose expression changed in response to elevated extracellular Mg(2+) in wild-type bacteria, a result that identifies CsrS as the principal, if not exclusive, sensor for extracellular Mg(2+) in GAS. (lu.se)

Currently, most protein sequences in databases are the result of translation of hypothetical transcripts derived from genomic sequencing data [ 3 ]. (biomedcentral.com)

We have performed molecular dynamics (MD) simulation of the thermal denaturation of one protein and one peptide-ubiquitin and melittin. (typeset.io)
Cortical circuit activity is shaped by the parvalbumin (PV) and somatostatin (SST) interneurons that inhibit principal excitatory (EXC) neurons and the vasoactive intestinal peptide (VIP) interneurons that suppress activation of other interneurons. (jneurosci.org)
ROA spectroscopy is able to probe the chiral peptide backbone of proteins, and as such the ROA spectrum of a protein contains a wealth of structural information from within the whole molecule, across the whole vibrational spectrum. (gla.ac.uk)

Domain motions are important for: ABC transporters catalysis cellular locomotion and motor proteins formation of protein complexes ion channels mechanoreceptors and mechanotransduction regulatory activity transport of metabolites across cell membranes[citation needed] One of the largest observed domain motions is the 'swivelling' mechanism in pyruvate phosphate dikinase. (wikipedia.org)

This approach has the advantage that it can be applied to any set of compartments and proteins, provided one has enough data. (biomedcentral.com)

2. The amino acid composition of the hen's egg protein was not significantly affected by variations in breed and diet. (cambridge.org)

Flexibility can also be observed in very high-resolution electron density maps produced by X-ray crystallography, particularly when diffraction data is collected at room temperature instead of the traditional cryogenic temperature (typically near 100 K). Information on the frequency distribution and dynamics of local protein flexibility can be obtained using Raman and optical Kerr-effect spectroscopy as well as anisotropic microspectroscopy in the terahertz frequency domain. (wikipedia.org)

HSP90 inhibition may also enhance synaptic protein expression via activation of heat shock factor 1 (HSF-1) transcriptional regulation 16 . (nature.com)
This is accomplished by increasing both the interaction strength and number of interactions among participant proteins, which is not necessarily accompanied by a change in expression levels. (nature.com)
Protein expression was investigated by ELISA and immunofluorescence, transcription factor-DNA binding by ELISA, gene expression by real-time PCR, prostaglandin E 2 (PGE 2 ) by radioimmunoassay, and matrix metalloproteinase (MMP) activity and nitric oxide (NO) production by fluorometry. (karger.com)
We used a genome-wide analysis which not only examined differential gene expression levels but could also detect differences in splice isoform usage. (jneurosci.org)
Protein Expression and Purification. (aston.ac.uk)
Differential protein expression between groups is thus highlighted and statistically significant protein "peaks" used to construct a panel of disease specific markers. (biomedcentral.com)
Differential protein expression profiling has the potential to be used for the detection of disease in TSE infected animals. (biomedcentral.com)
Differential expression analyses of the algivorous flagellate Orciraptor agilis (Viridiraptoridae, Cercozoa, Rhizaria) suggested the involvement of a highly expressed putative glycoside hydrolase of family GH5_5. (megazyme.com)
Whole genome analysis of lung, sampled 24 hours after challenge, showed expression changes of not only genes belonging to several Gene Ontology groups with up-regulation of inflammatory-associated genes and those associated with lung remodeling but also genes involved in downsizing these processes. (cdc.gov)

The location of many proteins in a cell is unclear or simply not known. (elifesciences.org)
Deletions in the stalk of the influenza neuraminidase (NA) surface protein are associated with increased virulence, but the mechanisms responsible for this enhanced virulence are unclear. (nih.gov)
The extent to which the conclusions drawn from the analysis of such proteins, which fold on the microsecond timescale, apply to the millisecond or slower folding of naturally occurring proteins is, however, unclear. (typeset.io)

Based on a comparative analysis of BPH and SBPH after transfer, the genes associated with sugar transporters and heat-shock proteins showed similar variation. (biomedcentral.com)

Nanoscale imaging enables the analysis of biological systems, such as cells and tissues, at the fundamental length scales of biomolecules and biomolecular interactions, but classically has required expensive equipment and advanced skillsets to perform, e . g ., via super-resolution microscopy [ 1 ]. (plos.org)
These types of tongues and noses are well suited for quality control of foodstuff, beverages, and biological species such as proteins or cells. (springer.com)
For biological systems, Q peaks were first observed in protein from different perspectives [3,7,9,13,15,21-23] , the detailed molec- powders and attributed to 1H-14N spin pairs [9], which were also ular mechanism of the ubiquitous 1H-14N Q peaks in biological sys- thought to be of critical importance for the background 1H relaxa- tems has not been established. (lu.se)

Here we use microsecond molecular dynamics simulations to explore the effect of stalk deletion on enzymatic activity, contrasting NA proteins from the A/swine/Shandong/N1/2009 strain both with and without a stalk deletion. (nih.gov)

This analysis reveals numerous examples of neuron subtype-specific isoform usage with functional importance, identifies potential drug targets, and provides insight into the neuron subtypes involved in psychiatric disease. (jneurosci.org)
The functional relevance of 14-3-3 proteins in the regulatory mechanism of their targets, however, is still not clear. (biomedcentral.com)
In this study, by combining metabolomics and genetical, enzymological, biochemical, and molecular approaches, we were able to draw a comprehensive map of the functional roles 14-3-3 proteins play in essential metabolic processes. (biomedcentral.com)
Although not statistically significant, compared to seropositive adults, infants have high serum levels of IgG and IgA -- the most common antibody found in blood and body fluids -- to SARS-CoV-2 spike protein with corresponding functional ability to block SARS-CoV-2 cellular entry. (indianweb2.com)

Kata Kunci : Near Infrared Spectroscopy (NIR), Principal Component Analysis (PCA), tepung. (ugm.ac.id)

Protein-protein interaction (PPI) networks and modules were constructed to identify hub genes with the Search Tool for the Retrieval of Interacting Genes/Proteins (STRING) and Cytoscape. (researchsquare.com)
For example, protein-truncating variants, which are genetic variants that shorten the coding sequence of genes, were associated with autism and behavioral abnormalities. (eurekalert.org)

The present data suggest that a family-centered point of view is necessary in the comparative analyses of cold- and warm-adapted enzymes, and enzymes belonging to the same family or superfamily have evolved similar structural and dynamic patterns to overcome the detrimental effects of low temperatures. (typeset.io)
Interestingly, the current data suggest that a family-centered point of view is necessary in the comparative analyses of cold- and warm-adapted enzymes. (typeset.io)
To this effect, leaf samples were subjected to comparative analysis using the near-isogenic non-GM hybrid as the comparator. (biosafety-info.net)
The comparative analysis of planthopper responses to different diets will improve our knowledge of host adaptation regarding herbivorous insects. (biomedcentral.com)
Comparative transcriptomic analysis of closely related taxa provides an ideal approach for revealing the distinctions in host adaptation across herbivorous species. (biomedcentral.com)

We initially used maps statically to generate a database with localization and absolute copy number information for over 8700 proteins from HeLa cells, approaching comprehensive coverage. (elifesciences.org)

Calibration of the method using predicted values of amino acid exposure allows classifying proteins without 3D-information with an accuracy of 62% and discerning proteins in different locations even if they shared high levels of identity. (biomedcentral.com)
Hampel M, Alonso E, Aparicio I, Santos JL & Leaver M (2015) Hepatic Proteome Analysis of Atlantic Salmon (Salmo salar) After Exposure to Environmental Concentrations of Human Pharmaceuticals. (stir.ac.uk)
Carbamazepine exposure resulted in 15 differently expressed proteins compared with the control, with 10 of them identified (seven up-regulated and three down-regulated). (stir.ac.uk)
We used hair analysis to evaluate the chronic internal exposure to three PCBs, seven organochlorine pesticides (OCs) and 18 non-persistent pesticides. (bvsalud.org)

The protein was captured in distinct states critical to function, including enzyme-substrate, enzyme-product, and enzyme-intermediate complexes. (rcsb.org)
Nitrate reductase is phosphorylated in the dark by the calcium-dependent protein kinase (CDPK) and the sucrose non-fermenting related kinase 1 (SnRK1) that initiates the interaction of the enzyme with the 14-3-3 proteins and its inactivation. (biomedcentral.com)
High purity dyed, soluble Azo-CM-Cellulose for the measurement of enzyme activity, for research, biochemical enzyme assays and in vitro diagnostic analysis. (megazyme.com)

A comparison of a normal mode analysis and principal component analysis of a 200-ps molecular dynamics trajectory of bovine pancreatic trypsin inhibitor in vacuum has been made in order to further elucidate the harmonic and anharmonic aspects in the dynamics of proteins. (uea.ac.uk)
Application of principal component analysis in protein unfolding: an all-atom molecular dynamics simulation study. (typeset.io)
Equilibrium molecular dynamics simulations, in which proteins spontaneously and repeatedly fold and unfold, have recently been used to help elucidate the mechanistic principles that underlie the folding of fast-folding proteins. (typeset.io)
The study of protein dynamics is most directly concerned with the transitions between these states, but can also involve the nature and equilibrium populations of the states themselves. (wikipedia.org)
The presence of multiple domains in proteins gives rise to a great deal of flexibility and mobility, leading to protein domain dynamics. (wikipedia.org)
They can also be suggested by sampling in extensive molecular dynamics trajectories and principal component analysis. (wikipedia.org)

Here we present a multifunctional anchor, an acrylate epoxide, that enables proteins and RNAs to be equipped with anchors in a single experimental step. (plos.org)
An antibody-protein array of putative immunogenic proteins was developed from a combined bioinformatic, experimental, and literature-based prioritization of homologous parasite proteins. (frontiersin.org)
The course covers the basics, principles and limitations for the most common methods for multivariate statistics (analysis of variance, principal component analysis and partial least squares regression), experimental design (super-saturated and factorial designs) and method validation with a focus on practical use. (lu.se)

Three proteins identified by SELDI-TOF analysis were verified by immunohistochemistry in brain tissue sections. (biomedcentral.com)
Definitive diagnosis has historically therefore, been restricted to post -mortem examination of brain tissue for the presence of pathological hallmarks of the disease such as spongiform changes and the deposition of an abnormal disease related form of the prion protein termed PrP d ( d denotes a disease associated form of the host encoded protein PrP c ) [ 5 ]. (biomedcentral.com)
Following an outbreak of BSE in cattle which was subsequently linked to the emergence of a new human form of the disease, vCJD, commercial testing for surveillance purposes has focused on detection of this protein (PrP d ) in brain tissue homogenates. (biomedcentral.com)
To contribute to the hazard identification of low molecular weight (LMW) respiratory allergens, respiratory allergy induced by trimellitic anhydride (TMA) was characterized by whole genome analysis of lung tissue and blood proteomics in Brown Norway rats. (cdc.gov)

As the database of ROA spectra of polypeptides and proteins has grown, it has been possible to tighten up the assignment of ROA spectral bands and band patterns to aspects of known structural content. (gla.ac.uk)

E7 from human papil omavirus type 16 cooperate to cancer: the European prospective investigation into doi:10.1093/carcin/bgp321 PMID:20047954 target the PDZ protein Na/H exchange regulatory cancer and nutrition study. (who.int)

Taken together, our findings indicate that 14-3-3 proteins play roles as crucial tuners of multiple primary metabolic processes including TCA cycle and the shikimate pathway. (biomedcentral.com)

We introduce the term protein connectivity-based dysfunction (PCBD) to define this mechanism. (nature.com)

Here, we used a genomics/proteomics approach (including immunoblot experiments from pigs infected with T. suis ) to prioritize putative immunogenic excretory/secretory (E/S) proteins conserved across and specific to several gastrointestinal (GI) parasitic nematode species. (frontiersin.org)
As well as containing detailed information from specific structural elements such as sections of secondary structure and motifs, the ability of ROA to see the molecule as a whole also enables the global fold of the protein to be deduced from the ROA spectrum. (gla.ac.uk)
In the principal components analysis (PCA), complex diet and multiple food groups are taking into account for pattern classification, instead of individual nutrients, specific foods or food groups. (biomedcentral.com)
Moreover, compared to their respective cells, iPSCs and iPSC EVs share a greater proportion of proteins, while the PD-MSC proteome appears to be more specific. (unlp.edu.ar)
Studies at both terminal stages of disease and throughout the time course of disease have shown a disease specific protein profile or "disease fingerprint" which could be used to distinguish between groups of TSE infected and uninfected animals at an early time point of disease. (biomedcentral.com)
To our knowledge, this study is the first to characterize global gene regulation by a GAS two-component system in response to a specific environmental stimulus. (lu.se)

On principal component analysis, infant immune responses appear distinct from their parents. (indianweb2.com)
The components of ERAS may be broadly divided into preadmission, preoperative, intraoperative, and postoperative phases, each of which includes various distinct components (see the image below). (medscape.com)

Principal Component Analysis (PCA) showed that females exhibited significantly higher levels of immune components than males did. (cdc.gov)

This added layer of analysis extracts the hidden information/patterns out of the data and allows visualization of the results. (springer.com)
Overall, results from principal component analysis showed that, among the three cultivars, Keumkang WWF was the most affected by the milling method. (hindawi.com)
The obtained results confirm that the studied dairy beverages constitute a valuable source of bioactive components with benefits in human healthy nutrition and medical purposes. (tubitak.gov.tr)
Results: Lung function, asthma control, and monocyte chemotactic protein-1 (MCP-1) were identified as the most important distinguisher and blood eosinophilia as second most important identifier in principal component analysis. (uzh.ch)

In this study, NIR technique was combined with Principal Component Analysis (PCA) to classify samples based on NIR spectra. (ugm.ac.id)
It is hoped that the result of this work will provide a basis for the future analysis of protein ROA spectra that is both mathematically rigorous and convenient. (gla.ac.uk)

We are proud to work together with the leading biotech company in Sweden for biomarker panel analyses in epidemiology, OLINK Proteomics AB, Uppsala, and its representatives! (lu.se)

Some of these conformational changes are induced by post-translational modifications in protein structure, such as phosphorylation and methylation. (wikipedia.org)

This work contributes to understanding structural characteristics responsible for taste and volatile profiles of protein hydrolysates. (ku.dk)

Combining spatial and abundance information yielded an unprecedented quantitative view of HeLa cell anatomy and organellar composition, at the protein level. (elifesciences.org)
A targeting signal prediction is, in principle, more reliable than a predicted location based on a close protein ortholog (or on a protein domain), which is itself better than location predicted on the basis of protein composition alone. (biomedcentral.com)
Les cycles hebdomadaires de menus du service de restauration des grands hôpitaux en Jordanie (n = 16) ont été analysés à l'aide du logiciel ESHA Food Processor pour obtenir des données sur la composition en macronutriments et en micronutriments ainsi que sur les groupes d'aliments représentés. (who.int)

These chapters include supervised and unsupervised methods, admixture analysis, an in-depth treatment of multivariate methods, and advice on how to handle GIS data. (routledge.com)

It should also include a disclaimer which credits any analyses, interpretations, or conclusions reached to the author (recipient of the tape) and not to NCHS, which is responsible only for the initial data. (cdc.gov)

Thesis: "Detection and Recognition of American Road Signs Via Principal Component Analysis. (uml.edu)
absence of detection of known motifs cannot be used to imply that a protein remains in the cytosol. (biomedcentral.com)
Current tests for the diagnosis of these diseases are based on the detection of an abnormal misfolded form of the host protein PrP which is found within the central nervous and lymphoreticular systems of affected animals. (biomedcentral.com)

Available online 25 January 2010 peaks have been linked to a dipolar flip-flop polarization transfer from 1H nuclei to rapidly relaxing amide 14N nuclei in rotationally immobilized proteins. (lu.se)

The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript. (plos.org)
The aim of this study was the determination of chromatographic profiles of major whey proteins (WP): α-lactalbumin (α-La), β-lactoglobulin A and B, (β-Lg A and B), bovine serum albumin (BSA) in dairy beverages based on Zonar milk serum. (tubitak.gov.tr)
The findings of this study demonstrated that 'High protein' pattern was positively associated with cognitive ability in Chinese children, while 'High fat' pattern exhibited a negative association. (biomedcentral.com)
Therefore, the study of protein function can be facilitated by predictions of protein location. (biomedcentral.com)
Our study further confirms that 14-3-3 proteins are important regulators of both nitrogen and carbon metabolic processes. (biomedcentral.com)
In contrast to other studies that used limited intra- and postoperative care elements, the authors maximized the use of ERAS care elements in the study population, including the preoperative components whenever feasible and most of the intraoperative and postoperative components. (medscape.com)

An anharmonicity factor is defined which measures the degree of anharmonicity in the modes, be they principal modes or normal modes, and it is shown that the principal mode system naturally divides into anharmonic modes with peak frequencies below 80 cm−1, and harmonic modes with frequencies above this value. (uea.ac.uk)

Anatomy6

Organisms3

Diseases1

Chemicals and Drugs4

Analytical, Diagnostic and Therapeutic Techniques and Equipment46

Psychiatry and Psychology3

Phenomena and Processes26

Disciplines and Occupations10

Anthropology, Education, Sociology and Social Phenomena1

Technology, Industry, Agriculture3

Humanities1

Information Science23

Named Groups1

Health Care22

Geographicals3

Differentially expressed4

Recombinant proteins1

Receptors1

Large number of proteins2

Dataset4

Pathways4

Characterization2

Target proteins3

Virulence Determinants1

Correlation5

Cell's2

Datasets2

Regulate2

Metabolism3

Proteome-wide2

Homology3

Eukaryotes2

Mass spectrometry3

Proteomic approach1

Structures8

Changes in protein2

Subcellular3

Extracellular1

Sequences1

Peptide3

Locomotion1

Compartments1

Amino acid composition1

Raman1

Expression9

Unclear3

Transporters1

Biological3

Deletion1

Functional4

Spectroscopy1

Genes2

Comparative5

Localization1

Exposure4

Enzyme3

Dynamics6

Experimental3

Tissue4

Grown1

Regulatory1

Roles1

Mechanism1

Specific6

Distinct2

Significantly1

Results4

Spectra2

Biomarker1

Phosphorylation1

Structural1

Composition3

Multivariate1

Conclusions1

Detection3

Peaks1

Study6

Naturally1