Proteins by rrna. Medical search. Frequent questions

In eukaryotic cells, the processing of the long, polycistronic ribosomal RNA precursor (pre-rRNA) involves a series of events that begin co-transcriptionally and occur simultaneously with ribosome assembly to ensure timely and accurate formation of the ribosomes [ 1 , 2 ]. (biomedcentral.com)
The processing of pre-rRNA takes place mainly in the nucleolus, and nucleoplasm, and the final steps of maturation are carried out after the export of the pre-ribosomes to the cytoplasm [ 1 , 3 ]. (biomedcentral.com)
Assembly of mitochondrial ribosomes requires nuclear encoded proteins and mitochondriaUy encoded ribosomal RNA (rRNA) particles. (nih.gov)
Messenger RNA (mRNA) then travels to the ribosomes in the cell cytoplasm, where protein synthesis occurs (Figure 3). (britannica.com)
Ribosomes are made up of ribosomal proteins and ribosomal RNA (rRNA). (britannica.com)
In prokaryotes, ribosomes are roughly 40 percent protein and 60 percent rRNA . (britannica.com)
In eukaryotes , ribosomes are about half protein and half rRNA. (britannica.com)
Ribosomes are usually made up of three or four rRNA molecules and anywhere from about 40 to 80 different ribosomal proteins. (britannica.com)
In animal cells, proteins are manufactured in molecular factories called ribosomes . (scienceblogs.com)
Ribosomes themselves are partially built form a special type of RNA known as rRNA . (scienceblogs.com)
One plausible explanation is that the CCD bees have more broken ribosomes, and have problems with producing proteins on demand. (scienceblogs.com)
The next step for Johnson is to try and show that being infected with many viruses results in more rRNA fragments, malfunctioning ribosomes, fewer important proteins and poorer health. (scienceblogs.com)
It is the site for transcribing rDNA into rRNA and for assembling ribosomes, aka ribosome biogenesis. (umassmed.edu)
The mitochondrial ribosomes (mitoribosomes) synthesize, almost exclusively, membrane proteins that are subunits of oxidative phosphorylation complexes. (molbiolcell.org)
Just as you wouldn't go to play tennis without your racket and ball, so a cell couldn't translate an mRNA into a protein without two pieces of molecular gear: ribosomes and tRNAs. (khanacademy.org)
Translation takes place inside structures called ribosomes , which are made of RNA and protein. (khanacademy.org)
Ribosomes organize translation and catalyze the reaction that joins amino acids to make a protein chain. (khanacademy.org)
They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. (sigmaaldrich.com)
Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. (sigmaaldrich.com)
The rRNA is an essential component of ribosomes, the sites of protein biosynthesis. (mpi-bremen.de)
Messenger RNA (mRNA) carries the blueprint (protein building instructions) copied from the cell's original DNA to the ribosomes. (internews.org)
The first is called ribosomal RNA (rRNA) and is used to manufacture ribosomes. (cliffsnotes.com)
Ribosomes are ultramicroscopic particles of rRNA and protein where amino acids are linked to one another during the synthesis of proteins. (cliffsnotes.com)
A second important type of RNA is transfer RNA (tRNA) , which is used to carry amino acids to the ribosomes for protein synthesis. (cliffsnotes.com)
Ribosomes ( / ˈ r aɪ b ə ˌ s oʊ m , - b oʊ -/ ) are macromolecular machines , found within all cells , that perform biological protein synthesis (mRNA translation). (wikipedia.org)
Ribosomes assemble polymeric protein molecules whose sequence is controlled by the sequence of messenger RNA molecules. (wikipedia.org)
Ribosomes bind to messenger RNAs and use their sequences for determining the correct sequence of amino acids to generate a given protein. (wikipedia.org)

Previous studies suggested an important functional interaction of the terminal residue A76 of E-tRNA with the nucleobase of the universally conserved 23S rRNA residue C2394. (nih.gov)
Cumulatively our data emphasize the importance of E-site tRNA occupancy and in particular the intactness of the 23S rRNA base pair G2421-C2395 for productive protein biosynthesis. (nih.gov)
The base triplets of transfer RNA (tRNA) pair with those of mRNA and at the same time deposit their amino acids on the growing protein chain. (britannica.com)
Pentatricopeptide repeats of protein-only RNase P use a distinct mode to recognize conserved bases and structural elements of pre-tRNA. (nih.gov)
Anticodon -- A sequence of three adjacent nucleotides in tRNA that binds to a complementary codon in mRNA and designates a specific amino acid during protein synthesis. (nih.gov)
Transfer RNA (tRNA) brings amino acids (raw material for building proteins) to the ribosome. (internews.org)
Three types of RNA "mRMA" "tRNA" "rRNA" are involved in the synthesis of proteins in the body. (gigazine.net)
Next, it is "Carriers" TRNA (Transfer RNA) carries the mRNA that copied the information to the ribosome that is the "protein factory" and finally constitutes the ribosome RRNA (Ribosomal RNA), the information of mRNA is copied and the protein is synthesized. (gigazine.net)
When protein synthesis is taking place, enzymes link tRNA to amino acids in a highly specific manner. (cliffsnotes.com)
Gene prediction was performed using Prodigal version 2.6, whereas rRNA and tRNA were predicted using RNAmmer and tRNAscan SE version 1.21. (scielo.br)
16723) hypothetical protein BBZA01000003 tRNA ARMA_tRNA01 complement(16745. (go.jp)

Mutations in two human genes, ERCC8/CSA and ERCC6/CSB, are causative for CS and their protein products, CSA and CSB, while structurally unrelated, play roles in DNA repair and other aspects of DNA metabolism in human cells. (nih.gov)
Importantly, the absence of AtNOL12 alters the expression of many ribosomal protein and ribosome biogenesis genes. (biomedcentral.com)
In these strains, mutations in the 23S rRNA gene were associated with macrolide resistance, and mutations in ribosomal protein genes L4 and L22 were also found ( 5 ). (cdc.gov)
To monitor macrolide susceptibilities in clinical strains of M. genitalium in Japan, therefore, we examined M. genitalium DNA found in the urine of men with NGU for the presence of macrolide resistance-associated mutations in the 23S rRNA gene and the ribosomal protein genes L4 and L22. (cdc.gov)
The 23S rRNA gene and the ribosomal proteins genes L4 and L22 of M. genitalium were amplified from the purified DNA by PCR as reported previously and then sequenced ( 5 ). (cdc.gov)
Evidence for the frequent use of TTG as the translation initiation codon of mitochondrial protein genes in the nematodes, Ascaris suum and Caenorhabditis elegans. (nih.gov)
Phylogenetic analysis of 16S rRNA and mnxG genes revealed that while many of the deep-sea Mn(II)-oxidizing Bacillus species are very closely related to previously recognized isolates from coastal sediments, other organisms represent novel strains and clusters. (nih.gov)
Other than an abundance of rRNA, Johnson found that 65 genes that were activated differently among sick bees compared to healthy ones. (scienceblogs.com)
The proteins produced from the TCOF1 , POLR1C , and POLR1D genes all appear to play important roles in the early development of bones and other tissues of the face. (nih.gov)
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. (sigmaaldrich.com)
In the next step, the products from the PCR are sequenced and the resulting sequences of the rRNA genes are compared with the already known sequences from public databases. (mpi-bremen.de)
Gene-FISH combines the detection of specific genes and ribosomal RNA (rRNA) at the single cell level. (mpi-bremen.de)
Usually, we combine geneFISH with 16S rRNA FISH to identify a group of microorganisms and study the presence of key metabolic genes. (mpi-bremen.de)
54 protein-encoding genes. (kenyon.edu)

The most well-described yeast counterpart, Rrp17, is required for maturation of 5.8 and 25S rRNAs, whereas human hNOL12 is crucial for the separation of the large (LSU) and small (SSU) ribosome subunit rRNA precursors. (biomedcentral.com)
Our investigation reveals the involvement of AtNOL12 in the maturation of rRNA precursors, correlating this process to stress response in Arabidopsis. (biomedcentral.com)
maturation of 5.8S rRNA, maturation of LSU-rRNA. (joplink.net)
Recent data showed that AATF is essential for ribosome biogenesis and plays a role in rRNA maturation. (uni-koeln.de)
These findings are complemented by an in-depth analysis of the protein interactome of AATF containing a large set of proteins known to play a role in rRNA maturation with an emphasis on the protein-RNA-complexes known to be required for the generation of the small ribosomal subunit (SSU). (uni-koeln.de)

Exonucleolytic digestion of a pre-rRNA molecule to generate the mature 5'-end of a 5.8S rRNA molecule derived from an originally tricistronic pre-rRNA transcript that contained the Small Subunit (SSU) rRNA, the 5.8S rRNA, and the Large Subunit (LSU) rRNA in that order from 5' to 3' along the primary transcript. (yeastrc.org)

Arsenic exposure was associated with decreased expression of ERCC1 in isolated lymphocytes at the mRNA and protein levels. (nih.gov)
The ribosome moves forward on the mRNA, codon by codon, as it is read and translated into a polypeptide (protein chain). (khanacademy.org)
When failure occurs at the stage of copying mRNA information performed in this ribosome, the synthesized protein Defective protein It will become impossible to fulfill the original role. (gigazine.net)
The third form of RNA is messenger RNA (mRNA) , which receives the genetic code from DNA and carries it into the cytoplasm where protein synthesis takes place. (cliffsnotes.com)
LOCUS AF028833 1063 bp mRNA PLN 10-NOV-1997 DEFINITION Dunaliella salina 60S ribosomal protein (DSRP1) mRNA, complete cds. (bio.net)
In all species, more than one ribosome may move along a single mRNA chain at one time (as a polysome ), each "reading" a specific sequence and producing a corresponding protein molecule. (wikipedia.org)

We show that Nop9 recognizes sequence and structural features of the 20S pre-rRNA near the cleavage site of the nuclease, Nob1. (nih.gov)
Pre-rRNA processing intermediates resulting from the A3 cleavage, namely the P-A3 and 27S-A3 species, are subsequently subjected to further endonucleolytic processing. (biomedcentral.com)
These results suggest that stationary phase-specific cleavage of 16S rRNA within the 30S subunit is an efficient means to reduce global translation activities under non-proliferating growth conditions. (nih.gov)
In line with this finding, the binding sites of AATF within the 45S rRNA precursor localize in close proximity to the SSU cleavage sites. (uni-koeln.de)

Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. (sigmaaldrich.com)
From the above-described rRNA sequence information, we cannot derive the abundance of a particular species or genus in the environmental sample. (mpi-bremen.de)
How the nitrogenous base code is translated to an amino acid sequence in a protein is the basis for protein synthesis. (cliffsnotes.com)
is the process in which the genetic code will be "translated" to an amino acid sequence in a protein. (cliffsnotes.com)
LOCUS AB007370 1733 bp DNA PLN 03-OCT-1997 DEFINITION Chlamydomonas tetragama gene for 18S rRNA, partial sequence. (bio.net)
Download DNA or protein sequence, view genomic context and coordinates. (yeastgenome.org)
Basic sequence-derived (length, molecular weight, isoelectric point) and experimentally-determined (median abundance, median absolute deviation) protein information. (yeastgenome.org)
Click "Protein Details" for further information about the protein such as half-life, abundance, domains, domains shared with other proteins, protein sequence retrieval for various strains, physico-chemical properties, protein modification sites, and external identifiers for the protein. (yeastgenome.org)
The sequence of DNA that encodes the sequence of the amino acids in a protein is transcribed into a messenger RNA chain. (wikipedia.org)
They differ in their size, sequence, structure, and the ratio of protein to RNA. (wikipedia.org)

During the 1950s and 1960s it became apparent that DNA is essential in the synthesis of proteins. (cliffsnotes.com)
The synthesis of proteins from their building blocks takes place in four phases: initiation, elongation, termination, and recycling. (wikipedia.org)

The primary rRNA transcript (35S in budding yeast, 47S in humans) is synthesized by RNA polymerase I (Pol I) and contains 5.8S, 18S and 25S ribosomal RNAs (rRNAs), as well as external and internal transcribed spacers (5′ETS, 3′ETS, ITS1, ITS2), which are removed during processing in a coordinated manner. (biomedcentral.com)

Enzyme -- A protein molecule that catalyzes chemical reactions of other substances without itself being destroyed or altered by the reactions. (nih.gov)
These proteins are involved in the production of a molecule called ribosomal RNA (rRNA), a chemical cousin of DNA. (nih.gov)
Using single-molecule fluorescence methods, we can correlate the timing of transcription of specific sequences with binding of RNA-binding proteins to the nascent RNA in order to understand how assembly proceeds in real time. (nih.gov)
The key element of a protein molecule is how the amino acids are linked. (cliffsnotes.com)

16S rRNA (guanine527-N7)-methyltransferase (EC 2.1.1.170, ribosomal RNA small subunit methyltransferase G, 16S rRNA methyltransferase RsmG, GidB, rsmG (gene)) is an enzyme with systematic name S-adenosyl-L-methionine:16S rRNA (guanine527-N7)-methyltransferase. (wikipedia.org)

We report that Nucleolin (Ncl), a nucleolar protein that regulates rRNA synthesis and ribosome biogenesis, interacts with CSA and CSB. (nih.gov)
During assembly, the rRNA must also interact with many RNA-binding proteins, including assembly factors, RNA chaperones, modification enzymes, and small nucleolar RNPs (snoRNPs), which alter the way the rRNA folds and assembles during transcription. (nih.gov)
Alopecia, neurological defects, and endocrinopathy syndrome caused by decreased expression of RBM28, a nucleolar protein associated with ribosome biogenesis. (nih.gov)
Human RBM28 protein is a specific nucleolar component of the spliceosomal snRNPs. (nih.gov)

In stationary-phase Escherichia coli, we observed the appearance of a 16S rRNA fragmentation event at the tip of helix 6 within the small ribosomal subunit (30S). (nih.gov)
Here, by employing a systematic mass spectrometry-based approach, we discovered the previously uncharacterized membrane protein Mrx15 that interacts via a soluble C-terminal domain with the large ribosomal subunit. (molbiolcell.org)
The ribosomal RNA (rRNA) is well-conserved, highly structured, and must bind dozens of ribosomal proteins to successfully assemble a ribosomal subunit. (nih.gov)

Stationary-phase 30S subunits showed markedly reduced activities in protein biosynthesis. (nih.gov)
Introduction of the 16S rRNA cut in vitro at helix 6 of exponential phase 30S subunits renders them less efficient in protein biosynthesis. (nih.gov)

We found amino acid changes in L4 and L22 ribosomal proteins in M. genitalium in 9 specimens. (cdc.gov)
Of the amino acid changes in L22 of M. genitalium , the only Gly93Glu change found in M. genitalium harboring the A2059G ( E. coli numbering) mutation in the 23S rRNA gene was located within the region corresponding to Arg88-Ala93 in L22 of E. coli . (cdc.gov)
Homology -- Similarity of nucleotide or amino acid sequences in nucleic acids, peptides, or proteins. (nih.gov)
They also catalyze the reaction that links amino acids to make a new protein. (khanacademy.org)
Amino acids are emerging to form a protein chain. (khanacademy.org)
The green spot marks the active site, which catalyzes the reaction that links amino acids to make a protein. (khanacademy.org)
14 B23.1, the prevalent isoform in all tissues, 15 contains 294 amino acids, 16 whereas B23.2, a truncated protein, lacks the last 35 C-terminal amino acids of B23.1 and is expressed at very low levels. (haematologica.org)
The sequences of amino acids, determined by genetic codes in DNA, distinguish one protein from another. (cliffsnotes.com)
One is a supply of the 20 amino acids which make up most proteins. (cliffsnotes.com)

NOL12 5′-3′ exoribonucleases, conserved among eukaryotes, play important roles in pre-rRNA processing, ribosome assembly and export. (biomedcentral.com)

This enzyme catalyses the following chemical reaction S-adenosyl-L-methionine + guanine527 in 16S rRNA ⇌ {\displaystyle \rightleftharpoons } S-adenosyl-L-homocysteine + N7-methylguanine527 in 16S rRNA The enzyme specifically methylates guanine527 at N7 in 16S rRNA. (wikipedia.org)

to others, the microsomes consist of protein and lipid contaminated by particles. (wikipedia.org)

Moreover, exposure of the nol12 mutant to stress factors, including heat and pathogen Pseudomonas syringae , enhances the observed molecular phenotypes, linking pre-rRNA processing to stress response pathways. (biomedcentral.com)
While the ribosomal A- and P-sites have been functionally well characterized in the past, the contribution of the E-site to protein biosynthesis is still poorly understood in molecular terms. (nih.gov)
Lecture 2, 04/09/09, thu In this lecture we reviewed some general background in molecular biology, particularly the central genetic process (from DNA to Proteins). (ubc.ca)

In this study we demonstrate that plant AtNOL12 is also involved in rRNA biogenesis, specifically in the processing of the LSU rRNA precursor, 27S pre-rRNA. (biomedcentral.com)
These changes could potentially exacerbate rRNA biogenesis defects, or, conversely, they might stem from the disturbed ribosome assembly caused by delayed pre-rRNA processing. (biomedcentral.com)
Taken together, our data reveal how these ribosome receptors organize membrane protein biogenesis in mitochondria. (molbiolcell.org)
Consequently, our multilayer analysis of the protein-RNA interactome of AATF reveals this protein to be an important hub for protein and RNA interactions involved in ribosome biogenesis. (uni-koeln.de)

These factories assemble proteins by translating instructions encoded within molecules of RNA. (scienceblogs.com)

Comparison of rRNA gene sequences provides information about the relatedness of the organisms from which the rRNA sequences originated. (mpi-bremen.de)
At first, we have to identify signature sequences in the rRNA that a are specific to the targeted taxonomic group of microorganisms. (mpi-bremen.de)
The peroxidase enzymatically binds these dye molecules to surrounding proteinsThis way, we can also visualize microorganisms that contain particularly few rRNA sequences and which we were unable to detect using the conventional method. (mpi-bremen.de)

Woodson, Sarah A. / Slow formation of stable complexes during coincubation of minimal rRNA and ribosomal protein S4 . (johnshopkins.edu)
Gene expression is driven by RNA-protein complexes, or ribonucleoproteins (RNPs), like the ribosome and the spliceosome. (nih.gov)
A ribosome is made from complexes of RNAs and proteins and is therefore a ribonucleoprotein complex . (wikipedia.org)

Formation of a RNP is a complicated process that requires coordination of dozens to hundreds of cellular factors to ensure that the proper structure of the RNAs and proteins is formed within the RNP. (nih.gov)

Mutations of A2058, A2059, and other 23S rRNA residues within the macrolide-binding site can confer a high-level resistance to macrolides in several bacterial species, including M. genitalium ( 5 , 9 ). (cdc.gov)
We also found a T-to-G transition at nucleotide position 2199 in the 23S rRNA gene of M. genitalium , corresponding to position 2185 in E. coli , in 3 specimens, but this mutation has not been associated with macrolide resistance in other bacterial species ( 9 ). (cdc.gov)
rRNA is a central component of the protein manufacturing machinery of all living cells, and is often used to analyze bacterial communities. (nih.gov)
DEC-205 (CD205), a member of the macrophage mannose receptor protein family, is the prototypic endocytic receptor of dendritic cells, whose ligands include phosphorothioated cytosine-guanosine (CpG) oligonucleotides, a motif often seen in bacterial or viral DNA. (uci.edu)
Fecal bacterial were analyzed based on 16S rRNA sequencing. (frontiersin.org)

In addition, CSA induces ubiquitination of Ncl, enhances binding of CSB to Ncl, and CSA and CSB both stimulate the binding of Ncl to rDNA and subsequent rRNA synthesis. (nih.gov)
In addition, nucleoli are dynamic hubs through which numerous proteins shuttle and contact specific non-rDNA genomic loci. (umassmed.edu)

p53 protein regulates Hsp90 ATPase activity and thereby Wnt signaling by modulating Aha1 expression. (nih.gov)
FLIM-FRET analysis of protein-protein interactions showed that PLIN5 S155 phosphorylation regulates PLIN5 interaction with adipose triglyceride lipase at the lipid droplet, but not with α-β hydrolase domain-containing 5. (uci.edu)

Ribonucleoprotein (RNP) assembly often occurs concurrently with transcription (i.e. co-transcriptionally) meaning that proteins bind to a nascent RNA as it is synthesized by RNA polymerase. (nih.gov)
Cells have developed complex mechanisms to coordinate transcription, nascent RNA folding, and protein association in order to achieve rapid and efficient RNP assembly for survival and proliferation. (nih.gov)

Experiments with minimal rRNA fragments show that this structural change depends only on 16S residues within the S4 binding site. (johnshopkins.edu)
MARV assembles and buds from the host cell plasma where MARV matrix protein (mVP40) dimers associate with anionic lipids at the plasma membrane inner leaflet and undergo a dynamic and extensive self-oligomerization into the structural matrix layer. (uci.edu)
Proteins are used as structural materials in the cells and function as enzymes. (cliffsnotes.com)

The results of this study suggest that specific proteins in breast milk can influence the abundance of certain gut microbes in infants, playing an important role in early immune and metabolic development. (frontiersin.org)

RNA carries instructions from the nuclear DNA into the cytoplasm, where protein is synthesized. (cliffsnotes.com)

Therefore, M. genitalium strains that harbor the A2059G ( E. coli numbering) mutation in the 23S rRNA gene could be highly macrolide resistant. (cdc.gov)

For example, in bacteria, flagella and pili are composed of protein. (cliffsnotes.com)

This gene encodes a 28S subunit protein. (sigmaaldrich.com)

Nor is it clear what the presence of the rRNA fragments means for the bees. (scienceblogs.com)

In 1 specimen, we found an A-to-G transition at nucleotide position 2072 in the 23S rRNA gene of M. genitalium , corresponding to position 2059 in Escherichia coli ( Table ). (cdc.gov)

The serum protein binding of azithromycin is variable in the concentration range approximating human exposure, decreasing from 51% at 0.02 mcg/mL to 7% at 2 mcg/mL. (nih.gov)

During the elongation cycle of protein biosynthesis, tRNAs traverse through the ribosome by consecutive binding to the 3 ribosomal binding sites (A-, P-, and E- sites). (nih.gov)

The resulting 35S pre-rRNA is further matured in two alternative ways (see Supplementary Fig. S1 A). In the major processing pathway, the 35S is cleaved within ITS1 segment, which separates the pre-rRNAs destined to the SSU (P-A3 pre-rRNA) and LSU (27S-A3 pre-rRNA). (biomedcentral.com)

The gene NPM1 that encodes for nucleophosmin (NPMI) is translocated or mutated in various lymphomas and leukemias, forming fusion proteins (NPM-ALK, NPM-RARa, NPM-MLF1) or NPM mutant products. (haematologica.org)
AT7 genome contains 2.4 Mb and encodes 2388 proteins. (kenyon.edu)

Lipid-specific oligomerization of the Marburg virus matrix protein VP40 is regulated by two distinct interfaces for virion assembly. (uci.edu)
Perilipin 5 (PLIN5) is a lipid-droplet-associated protein that coordinates intracellular lipolysis in highly oxidative tissues and is thought to regulate lipid metabolism in response to phosphorylation by protein kinase A (PKA). (uci.edu)

The additional 5S rRNA is synthesized independently by the RNA polymerase III (Pol III) [ 3 ]. (biomedcentral.com)
The schematic workflow can be seen on the right: In the laboratory, the entire DNA is isolated from the environmental sample and the gene segments coding for the rRNA are amplified with specific primers using polymerase chain reaction (PCR). (mpi-bremen.de)

An A2059 ( E. coli numbering) residue in region V of the 23S rRNA gene is critical for the binding of macrolides ( 9 ). (cdc.gov)

4 Nucleophosmin is an essential protein, since inactivation of the gene encoding for nucleophosmin ( NPM1 ) in the mouse germ line leads to developmental defects that cause embryonic death in mid-gestation. (haematologica.org)

It also requires site-specific methylation of a small number of nucleotides within the rRNA, a process that utilizes Adomet. (nih.gov)

It is hoped that these analyses will provide a unique insight into the role of mitochondrial protein translation I the progression of ALD. (nih.gov)

Mycobacterium-specific primers based on 65-kDa heat shock protein (hsp) gene, and Pseudomonas-specific primers based on 16S rRNA gene were used. (cdc.gov)

This review focuses on experimental work investigating the interactions and functions of RNA and nucleic acid processing proteins with Fe 2+ under anoxic, early Earth conditions. (springer.com)

Once the protein is produced, it can then fold to produce a functional three-dimensional structure. (wikipedia.org)

9. Expression of the tumor-expressed protein MageB2 enhances rRNA transcription. (nih.gov)
10. Human MageB2 Protein Expression Enhances E2F Transcriptional Activity, Cell Proliferation, and Resistance to Ribotoxic Stress. (nih.gov)

These elements of the S4 binding site may require other 30S proteins to reach a stable conformation. (johnshopkins.edu)

Ribosomal protein S4 binds and stabilizes a five-helix junction or five-way junction (5WJ) in the 5′ domain of 16S ribosomal RNA (rRNA) and is one of two proteins responsible for nucleating 30S ribosome assembly. (johnshopkins.edu)

The RNA has a crucial job which is to carry DNA instructions, stored in its genetic code on how to build new proteins, from the nucleus to other parts of the cell where the proteins are manufactured. (internews.org)
In this way, a genetic code in the DNA can be used to synthesize a protein at a distant location at the ribosome. (cliffsnotes.com)

2022. Bipartite interaction sites differentially modulate RNA-binding affinity of a protein complex essential for germline stem cell self-renewal. (nih.gov)
AATF has been implicated to fulfil this role through direct interaction with rRNA and was identified in several RNA-interactome capture experiments. (uni-koeln.de)

This study aims to explore the correlation between functional proteins in breast milk and the infant gut microbiota. (frontiersin.org)
While the presence of a certain gene is indicative of a specific functional trait, the rRNA allows for the taxonomic affiliation of the microorganism. (mpi-bremen.de)

Under suitable experimental conditions, the probes bind to the rRNA of the target organisms only. (mpi-bremen.de)

Mrx15 contacts mitochondrial translation products during their synthesis and plays, together with the ribosome receptor Mba1, an overlapping role in cotranslational protein insertion. (molbiolcell.org)
Heat shock protein 90 inhibitors suppress aryl hydrocarbon receptor-mediated activation of CYP1A1 and CYP1B1 transcription and DNA adduct formation. (nih.gov)
Here we describe the 3.2 Å cryo-EM structure of human DEC-205, thereby illuminating the structure of the mannose receptor protein family. (uci.edu)

Anatomy12

Organisms65

Diseases4

Chemicals and Drugs73

Analytical, Diagnostic and Therapeutic Techniques and Equipment23

Phenomena and Processes64

Disciplines and Occupations5

Anthropology, Education, Sociology and Social Phenomena1

Technology, Industry, Agriculture1

Information Science5

Health Care20

Geographicals8

Ribosomes27

TRNA11

Genes14

Maturation5

Large subunit1

MRNA6

Cleavage4

Sequence10

Synthesis of proteins2

Transcript1

Molecule4

Methyltransferase1

Nucleolar4

Ribosomal subunit3

Subunits2

Amino9

Eukaryotes1

Enzyme1

Particles1

Molecular3

Biogenesis4

Assemble1

Sequences3

Complexes3

RNAs1

Bacterial5

RDNA2

Regulates2

Nascent2

Structural3

Abundance1

Cytoplasm1

A2059G1

Bacteria1

Subunit protein1

Fragments1

Nucleotide1

Azithromycin1

Biosynthesis1

ITS11

Encodes2

Lipid2

Polymerase2

Residue1

Defects1

Nucleotides1

Mitochondrial protein1

Primers1

Nucleic1

Fold1

Enhances2

Conformation1

Binds1

Genetic code2

Interaction2

Functional2

Bind1

Receptor3