Tumor Suppressor Protein p53MutationTumor Suppressor ProteinsGenes, Tumor SuppressorMolecular Sequence DataAmino Acid SequenceProto-Oncogene Proteins c-mdm2Cell LineBase SequenceProtein BindingVon Hippel-Lindau Tumor Suppressor ProteinNuclear ProteinsCyclin-Dependent Kinase Inhibitor p21Cell Line, TumorGenes, p53ApoptosisTumor Suppressor Protein p14ARFTransfectionDNA-Binding ProteinsCyclinsProtein Structure, TertiaryRetinoblastoma ProteinTumor Cells, CulturedBinding SitesPoint MutationProto-Oncogene ProteinsTranscriptional ActivationDNA DamageCell CycleRecombinant Fusion ProteinsPromoter Regions, GeneticTranscription FactorsMutation, MissenseTranscription, GeneticCell Cycle ProteinsPhosphorylationGene Expression Regulation, NeoplasticUbiquitin-Protein LigasesCell NucleusSignal TransductionRecombinant ProteinsCell ProliferationOncogene Proteins, ViralBlotting, WesternRNA, MessengerDNACell DivisionAdenovirus E1B ProteinsDown-RegulationHeLa CellsFibroblastsUltraviolet RaysGene Expression RegulationMembrane ProteinsNeoplasmsUbiquitinsNeurofibromin 2Cells, CulturedDNA PrimersAdenomatous Polyposis Coli ProteinAntigens, Polyomavirus TransformingGenes, Suppressorbcl-2-Associated X ProteinPrecipitin TestsConsensus SequenceCyclin-Dependent Kinase Inhibitor p16Proteasome Endopeptidase ComplexTrans-ActivatorsCell Transformation, NeoplasticPTEN PhosphohydrolaseSpodopteraCloning, MolecularSequence Homology, Amino AcidNeoplasm ProteinsProteinsMice, KnockoutRepressor ProteinsModels, BiologicalProtein-Serine-Threonine KinasesCell SurvivalProto-Oncogene Proteins c-bcl-2AcetylationLigasesPapillomaviridaeE2F Transcription FactorsSuppression, GeneticCarrier ProteinsSerineRNA, Small InterferingAmino Acid MotifsFrameshift MutationPolymerase Chain ReactionGene DeletionTumor Markers, BiologicalModels, MolecularGerm-Line MutationRetinoblastoma-Like Protein p107Gene SilencingEscherichia coliReverse Transcriptase Polymerase Chain Reaction