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  • biosynthesis
  • Cell biological studies of the synthesis of yolk protein precursors by the insect's metabolic tissue and their accumulation by developing oocytes were followed by biochemical investigation of vitellogenin (Vg) biosynthesis, the major yolk protein precursor. (ucr.edu)
  • The precursor-product relationship and the major steps in biosynthesis of mosquito Vg, as well as the analysis of its protein sequence, have been pursued. (ucr.edu)
  • Dolichyl monophosphate is an essential glycosyl carrier lipid for C- and O-mannosylation and N-glycosylation of proteins and for biosynthesis of glycosylphosphatidylinositol anchors in endoplasmic reticulum (ER). (wikipedia.org)
  • membrane protein
  • Compared to other classes of proteins, the determination of membrane protein structures has remained a challenge in large part due to the difficulty in establishing experimental conditions where the correct conformation of the protein in isolation from its native environment is preserved. (wikipedia.org)
  • The TIM23 complex is made up of the subunits Tim17, Tim21 and Tim23, which are thought to contribute to the structural formation of the translocation channel that spans the inner membrane, and Tim44, which is a peripheral membrane protein. (wikipedia.org)
  • Interactions
  • The book presents various delivery systems (including nano-emulsions, solid lipid nanoparticles, and polymeric nano-particles), their properties and interactions with other food components, and fate in the human body. (wiley.com)
  • molecules
  • Two or more ions or molecules share the carrier. (brainscape.com)
  • Transport proteins move molecules and ions across the membrane. (wikipedia.org)
  • For example, in insects, the desaturase is critical in the formation of ceramide, and for complex signalling molecules (pheremones), while in fungi, the function of the enzyme, and concentration of unsaturated lipids is regulated in response to function of growth temperature by controlling membrane fluidity in cells. (wikipedia.org)
  • As such, many lipid signaling molecules cannot circulate freely in solution but, rather, exist bound to special carrier proteins in serum. (wikipedia.org)
  • hydrophobic
  • Fatty acid binding proteins are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. (wikipedia.org)
  • It is possible that this small Tim complex is able to stabilise precursor carrier proteins by acting as a chaperone and preventing the hydrophobic precursors from aggregating in the aqueous environment of the intermembrane space. (wikipedia.org)
  • ileal
  • The SLC10A2 (solute carrier family 10 member 2) gene in humans encodes the bile acid:sodium symporter known as the apical sodium-bile acid transporter (ASBT) or as the ileal bile acid transporter (IBAT). (wikipedia.org)
  • Fatty acid binding protein 6, ileal (gastrotropin), also known as FABP6, is a protein which in humans is encoded by the FABP6 gene. (wikipedia.org)
  • 1999). "Identification of a bile acid-responsive element in the human ileal bile acid-binding protein gene. (wikipedia.org)
  • Cellular
  • Lipid signaling, broadly defined, refers to any biological signaling event involving a lipid messenger that binds a protein target, such as a receptor, kinase or phosphatase, which in turn mediate the effects of these lipids on specific cellular responses. (wikipedia.org)
  • precursors
  • This was the first demonstration that subtilisin-like pro-protein convertases, which are serine proteases implicated in proteolytic processing of neurohormone precursors, are involved in the processing of a major secretory protein. (ucr.edu)
  • Polypeptide
  • Polypeptide toxins and many antibacterial peptides, such as colicins or hemolysins, and certain proteins involved in apoptosis, are sometimes considered a separate category. (wikipedia.org)
  • enzymes
  • These include enzymes called ceramide-activated Ser-Thr phosphatases (CAPPs), such as protein phosphatase 1 and 2A (PP1 and PP2A), which were found to interact with ceramide in studies done in a controlled environment outside of a living organism (in vitro). (wikipedia.org)
  • On the other hand, studies in cells have shown that ceramide-inducing agents such as tumor necrosis factor-alpha α (TNFα) and palmitate induce the ceramide-dependent removal of a phosphate group (dephosphorylation) of the retinoblastoma gene product RB and the enzymes, protein kinases B (AKT protein family) and C α (PKB and PKCα). (wikipedia.org)
  • cholesterol
  • Chylomicrons are in the class of lipids, which includes both triglycerides and cholesterol, and which are formed during the digestion of fats from food. (petmd.com)
  • You're probably concerned about your cholesterol level, but if you're like most, you find the language about cholesterol and other lipids - fatty substances in the body - confusing. (adclinic.com)
  • Cholesterol is transported through the blood stream by lipoproteins (lipid plus protein) carriers. (adclinic.com)
  • Low-fat, low-cholesterol eating benefits all your lipid levels. (adclinic.com)
  • apoptosis
  • This protein likely functions as a trigger for apoptosis through upregulation of genes necessary for cell death, such as Bim and PUMA, or downregulation of anti-apoptotic proteins such as FLIP. (wikipedia.org)
  • Vesicles
  • One consequence of this is that lipid messengers cannot be stored in vesicles prior to release and so are often biosynthesized "on demand" at their intended site of action. (wikipedia.org)