• The highest score is taken to indicate the protein conformation. (programmableweb.com)
  • However, analytical monitoring of the protein conformation has been frequently omitted due to time constraints, the complexity of techniques commonly employed and the inherent lack of sensitivity to subtle changes shown by some biophysical methods. (com.bd)
  • Suppression of conformational heterogeneity at a protein-protein interface. (duke.edu)
  • Background Protein structures are flexible and often show conformational changes upon binding to other molecules to exert biological functions. (ebscohost.com)
  • By analyzing these properties, we can provide you with valuable information on secondary, tertiary and quaternary structures of protein molecules, such as monoclonal antibodies, and provide evidence that the molecule maintains conformational stability. (com.bd)
  • Other extended structures such as the polyproline helix and alpha sheet are rare in native state proteins but are often hypothesized as important protein folding intermediates. (wikipedia.org)
  • The statistical bias toward native secondary structure in helix (red), strand (green), turn (blue), and generalized turn (black) for all segments in Table 2 is parceled into bins, with statistical weights that range from 0.0 to 1.0 in increments of 0.1. (pnas.org)
  • Previous work by Hunter and States had applied a similar Bayesian classification method, AutoClass, to protein data with site position represented by 3 Cartesian co-ordinates for each of the α-Carbon, β-Carbon and Nitrogen, totalling 9 co-ordinates. (psu.edu)
  • Physical contacts between proteins have been revealed using experimental approaches that have solved the structures of protein complexes at atomic resolution. (ebscohost.com)
  • Experimental results show that DeepCNF can obtain ~84% Q3 accuracy, ~85% SOV score, and ~72% Q8 accuracy, respectively, on the CASP and CAMEO test proteins, greatly outperforming currently popular predictors. (arxiv.org)
  • Biomolecular NMR spectroscopy frequently employs estimates of protein secondary structure using secondary chemical shift (Δδ) values, measured as the difference between experimental and random coil chemical shifts (RCCS). (springer.com)
  • Two new RCCS sets are presented here, determined in dimethyl sulfoxide (DMSO) and chloroform:methanol:water (4:4:1 by volume) at 298 K. A web-based program, CS-CHEMeleon, has been implemented to determine the accuracy of secondary structure assessment by calculating and comparing Δδ values for various RCCS datasets. (springer.com)
  • Despite obvious RCCS variations between datasets, prediction of secondary structure was consistently similar. (springer.com)
  • 2003). Elimination of the Disulfide Bridge in the Rieske Iron?Sulfur Protein Allows Assembly of the [2Fe-2S] Cluster into the Rieske Protein but Damages the Ubiquinol Oxidation Site in the Cytochrome bc1 Complex. (olisweb.com)
  • 2013). Hydrophobic enhancement of Dopamediated adhesion in a mussel foot protein. (olisweb.com)
  • Electrostatic Energetics of Bacillus subtilis Ribonuclease P Protein Determined by Nuclear Magnetic Resonance-Based Histidine pKa Measurements. (duke.edu)
  • The inclusion of protein family information in this form increases the prediction accuracy by six to eight percentage points. (nih.gov)