Tumor Suppressor Protein p53Tumor Suppressor ProteinsGenes, Tumor SuppressorVon Hippel-Lindau Tumor Suppressor ProteinProtein BindingMolecular Sequence DataTumor Suppressor Protein p14ARFRetinoblastoma ProteinProtein Interaction MappingAmino Acid SequenceTranscription FactorsCell Line, TumorProto-Oncogene Proteins c-mdm2Two-Hybrid System TechniquesProtein Structure, TertiaryBinding SitesCell LineBase SequenceGenes, p53MutationNuclear ProteinsNeurofibromin 2Gene Expression Regulation, NeoplasticApoptosisAdenomatous Polyposis Coli ProteinDNA-Binding ProteinsTransfectionCell CycleModels, MolecularCyclin-Dependent Kinase Inhibitor p16Ubiquitin-Protein LigasesGenes, SuppressorTumor Cells, CulturedPTEN PhosphohydrolaseProto-Oncogene ProteinsCyclin-Dependent Kinase Inhibitor p21Cell Cycle ProteinsPromoter Regions, GeneticCell Transformation, NeoplasticSignal TransductionProtein ConformationCell ProliferationDNA DamagePhosphorylationNeoplasmsCell DivisionLigasesNeoplasm ProteinsCyclinsE2F Transcription FactorsTranscription, GeneticRepressor ProteinsTranscriptional ActivationDown-RegulationProteinsRNA, MessengerBlotting, WesternTumor Markers, BiologicalGene SilencingE2F1 Transcription FactorSuppressor of Cytokine Signaling ProteinsProtein-Serine-Threonine KinasesTranscription Factor DP1Carrier ProteinsDNA MethylationLoss of HeterozygositySuppression, GeneticKidney NeoplasmsRNA InterferenceFibroblastsHeLa CellsOncogene Proteins, ViralReverse Transcriptase Polymerase Chain ReactionPapillomavirus E7 ProteinsRecombinant Fusion ProteinsRNA, Small InterferingWT1 ProteinsGene Expression RegulationCells, CulturedRetinoblastoma-Binding Protein 1Gene DeletionTumor BurdenCell NucleusTrans-ActivatorsRetinoblastoma-Like Protein p107Tumor Necrosis Factor-alphaWilms TumorDNA PrimersBreast NeoplasmsProteasome Endopeptidase ComplexImmunohistochemistryDNA, NeoplasmG1 PhaseHypoxia-Inducible Factor 1, alpha SubunitCell AgingMice, NudeMembrane ProteinsGenes, RetinoblastomaMice, KnockoutOsteosarcoma